메뉴 건너뛰기




Volumn 40, Issue 10, 2008, Pages 708-712

Adiponectin and leptin are independently associated with insulin sensitivity, but not with insulin secretion or beta-cell function in overweight hispanic adolescents

Author keywords

Adiponectin; Beta cell function; Insulin sensitivity; Leptin

Indexed keywords

ADIPONECTIN; LEPTIN;

EID: 50649115441     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1077097     Document Type: Article
Times cited : (26)

References (43)
  • 1
    • 33745244801 scopus 로고    scopus 로고
    • Development of type 2 diabetes in children and adolescents
    • Weiss R, Taksali SE, Caprio S. Development of type 2 diabetes in children and adolescents. Cutr Diab Rep 2006; 6: 182-187
    • (2006) Cutr Diab Rep , vol.6 , pp. 182-187
    • Weiss, R.1    Taksali, S.E.2    Caprio, S.3
  • 2
    • 0037956818 scopus 로고    scopus 로고
    • Insulin resistance and associated compensatory responses in African-American and Hispanic children
    • Goran MI, Bergman RN, Cruz ML, Watanabe R. Insulin resistance and associated compensatory responses in African-American and Hispanic children. Diabetes Care 2002; 25: 2184-2190
    • (2002) Diabetes Care , vol.25 , pp. 2184-2190
    • Goran, M.I.1    Bergman, R.N.2    Cruz, M.L.3    Watanabe, R.4
  • 3
    • 0842269769 scopus 로고    scopus 로고
    • Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes
    • Goran MI, Bergman RN, Avila Q et al. Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes. J Clin Endocrinol Metab 2004; 89: 207-212
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 207-212
    • Goran, M.I.1    Bergman, R.N.2    Avila, Q.3
  • 4
    • 25644435715 scopus 로고    scopus 로고
    • Decreased beta-cell function in overweight Latino children with impaired fasting glucose
    • Weigensberg MJ, Ball GD, Shaibi GQ, Cruz ML, Goran MI. Decreased beta-cell function in overweight Latino children with impaired fasting glucose. Diabetes Care 2005; 28: 2519-2524
    • (2005) Diabetes Care , vol.28 , pp. 2519-2524
    • Weigensberg, M.J.1    Ball, G.D.2    Shaibi, G.Q.3    Cruz, M.L.4    Goran, M.I.5
  • 5
    • 0022652051 scopus 로고
    • Impaired insulin action in puberty. A contributing factor to poor glycemic control in adolescents with diabetes
    • Amiel SA, Sherwin RS, Simonson DC, Lauritano AA, Tamborlane WV. Impaired insulin action in puberty. A contributing factor to poor glycemic control in adolescents with diabetes. N Engl J Med 1986; 315: 215-219
    • (1986) N Engl J Med , vol.315 , pp. 215-219
    • Amiel, S.A.1    Sherwin, R.S.2    Simonson, D.C.3    Lauritano, A.A.4    Tamborlane, W.V.5
  • 6
    • 0035512070 scopus 로고    scopus 로고
    • Longitudinal study on pubertal insulin resistance
    • Goran MI, Gower BA. Longitudinal study on pubertal insulin resistance. Diabetes 2001; 50: 2444-2450
    • (2001) Diabetes , vol.50 , pp. 2444-2450
    • Goran, M.I.1    Gower, B.A.2
  • 7
    • 30744448677 scopus 로고    scopus 로고
    • Longitudinal changes in insulin sensitivity, insulin secretion, and beta-cell function during puberty
    • Ball GD, Huang TT, Gower BA et al. Longitudinal changes in insulin sensitivity, insulin secretion, and beta-cell function during puberty. J Pediatr 2006; 148: 16-22
    • (2006) J Pediatr , vol.148 , pp. 16-22
    • Ball, G.D.1    Huang, T.T.2    Gower, B.A.3
  • 8
    • 27744539430 scopus 로고    scopus 로고
    • Insulin sensitivity, insulin secretion and beta-cell function during puberty in overweight Hispanic children with a family history of type 2 diabetes
    • Ball CD, Weigensberg MJ, Cruz ML et al. Insulin sensitivity, insulin secretion and beta-cell function during puberty in overweight Hispanic children with a family history of type 2 diabetes. Int J Obes (Lond) 2005; 29: 1471-1477
    • (2005) Int J Obes (Lond) , vol.29 , pp. 1471-1477
    • Ball, C.D.1    Weigensberg, M.J.2    Cruz, M.L.3
  • 9
    • 34147145174 scopus 로고    scopus 로고
    • Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: A longitudinal assessment
    • Goran MI, Shaibi GQ, Weigensberg MJ, Davis JN, Cruz ML. Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: A longitudinal assessment. Int J Pediatr Obes 2006; 1: 139-145
    • (2006) Int J Pediatr Obes , vol.1 , pp. 139-145
    • Goran, M.I.1    Shaibi, G.Q.2    Weigensberg, M.J.3    Davis, J.N.4    Cruz, M.L.5
  • 10
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001; 414: 799-806
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 11
    • 33745197808 scopus 로고    scopus 로고
    • The role of leptin in leptin resistance and obesity
    • Zhang Y, Scarpace PJ. The role of leptin in leptin resistance and obesity. Physiol Behav 2006; 88: 249-256
    • (2006) Physiol Behav , vol.88 , pp. 249-256
    • Zhang, Y.1    Scarpace, P.J.2
  • 12
    • 0036790520 scopus 로고    scopus 로고
    • The function of leptin in nutrition, weight, and physiology
    • discussion S68-S84, S85-S87
    • Friedman JM. The function of leptin in nutrition, weight, and physiology. Nutr Rev 2002; 60: S1-S14; discussion S68-S84, S85-S87
    • (2002) Nutr Rev , vol.60
    • JM, F.1
  • 13
    • 1542390736 scopus 로고    scopus 로고
    • Relation of leptin to insulin resistance syndrome in children
    • Steinberger J, Steffen L, Jacobs Jr DR et al. Relation of leptin to insulin resistance syndrome in children. Obes Res 2003; 11: 1124-1130
    • (2003) Obes Res , vol.11 , pp. 1124-1130
    • Steinberger, J.1    Steffen, L.2    Jacobs Jr, D.R.3
  • 14
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8: 1288-1295
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3
  • 15
    • 0036678916 scopus 로고    scopus 로고
    • Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women
    • Matsubara M, Maruoka S, Katayose S. Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. Eur J Endocrinol 2002; 147: 173-180
    • (2002) Eur J Endocrinol , vol.147 , pp. 173-180
    • Matsubara, M.1    Maruoka, S.2    Katayose, S.3
  • 16
    • 33748610249 scopus 로고    scopus 로고
    • Adiponectin expression is paradoxically increased in gold-thioglucose-induced obesity
    • Huypens P, Quartier E. Adiponectin expression is paradoxically increased in gold-thioglucose-induced obesity. Horm Metab Res 2006; 38: 486-490
    • (2006) Horm Metab Res , vol.38 , pp. 486-490
    • Huypens, P.1    Quartier, E.2
  • 17
    • 33646267470 scopus 로고    scopus 로고
    • Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes
    • Thamer C, Haap M, Heller E et al. Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes. Horm Metab Res 2006; 38: 178-182
    • (2006) Horm Metab Res , vol.38 , pp. 178-182
    • Thamer, C.1    Haap, M.2    Heller, E.3
  • 18
    • 0030965884 scopus 로고    scopus 로고
    • Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
    • Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 1997; 46: 313-316
    • (1997) Diabetes , vol.46 , pp. 313-316
    • Emilsson, V.1    Liu, Y.L.2    Cawthorne, M.A.3    Morton, N.M.4    Davenport, M.5
  • 19
    • 0035125097 scopus 로고    scopus 로고
    • Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo
    • Cases JA, Gabriely I, Ma XH et al. Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes 2001; 50: 348-352
    • (2001) Diabetes , vol.50 , pp. 348-352
    • Cases, J.A.1    Gabriely, I.2    Ma, X.H.3
  • 20
    • 0842333086 scopus 로고    scopus 로고
    • Adiponectin in youth: Relationship to visceral adiposity, insulin sensitivity, and beta-cell function
    • Bacha F, Saad R, Gungor N, Arslanian SA. Adiponectin in youth: relationship to visceral adiposity, insulin sensitivity, and beta-cell function. Diabetes Care 2004; 27: 547-552
    • (2004) Diabetes Care , vol.27 , pp. 547-552
    • Bacha, F.1    Saad, R.2    Gungor, N.3    Arslanian, S.A.4
  • 21
    • 28744439955 scopus 로고    scopus 로고
    • Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis
    • Staiger K, Stefan N, Staiger H et al. Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis. J Clin Endocrinol Metab 2005; 90: 6707-6713
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6707-6713
    • Staiger, K.1    Stefan, N.2    Staiger, H.3
  • 22
    • 0032566008 scopus 로고    scopus 로고
    • Failure of human and mouse leptin to affect insulin, glucagon and somatostatin secretion by the perfused rat pancreas at physiological glucose concentration
    • Leclercq-Meyer V, Malaisse WJ. Failure of human and mouse leptin to affect insulin, glucagon and somatostatin secretion by the perfused rat pancreas at physiological glucose concentration. Mol Cell Endocrinol 1998; 141: 111-118
    • (1998) Mol Cell Endocrinol , vol.141 , pp. 111-118
    • Leclercq-Meyer, V.1    Malaisse, W.J.2
  • 23
    • 0034950377 scopus 로고    scopus 로고
    • Long-term leptin treatment of ob/ob mice improves glucose-induced insulin secretion
    • Khan A, Narangoda S, Ahren B et al. Long-term leptin treatment of ob/ob mice improves glucose-induced insulin secretion. Int J Obes Relat Metab Disord 2001; 25: 816-821
    • (2001) Int J Obes Relat Metab Disord , vol.25 , pp. 816-821
    • Khan, A.1    Narangoda, S.2    Ahren, B.3
  • 24
    • 0038583808 scopus 로고    scopus 로고
    • Leptin levels in type 2 diabetes: Associations with measutes of insulin resistance and insulin secretion
    • Wauters M, Considine RV, Yudkin JS et al. Leptin levels in type 2 diabetes: associations with measutes of insulin resistance and insulin secretion. Horm Metab Res 2003; 35: 92-96
    • (2003) Horm Metab Res , vol.35 , pp. 92-96
    • Wauters, M.1    Considine, R.V.2    Yudkin, J.S.3
  • 25
    • 0031732754 scopus 로고    scopus 로고
    • Leptin levels, beta-cell function, and insulin sensitivity in families with congenital and acquired generalized lipoatropic diabetes
    • Pardini VC, Victoria IM, Rocha SM et al. Leptin levels, beta-cell function, and insulin sensitivity in families with congenital and acquired generalized lipoatropic diabetes. J Clin Endocrinol Metab 1998; 83: 503-508
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 503-508
    • Pardini, V.C.1    Victoria, I.M.2    Rocha, S.M.3
  • 26
    • 0842269788 scopus 로고    scopus 로고
    • The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity
    • Cruz ML, Weigensberg MJ, Huang TT et al. The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity. J Clin Endocrinol Metab 2004; 89: 108-113
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 108-113
    • Cruz, M.L.1    Weigensberg, M.J.2    Huang, T.T.3
  • 27
    • 54049086023 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. CDC growth Charts. In: U.S. Department of Health and Human Services CfDCaP ed. National Center for Health Statistics 2000
    • Centers for Disease Control and Prevention. CDC growth Charts. In: U.S. Department of Health and Human Services CfDCaP ed. National Center for Health Statistics 2000
  • 28
    • 0342980364 scopus 로고    scopus 로고
    • Type 2 diabetes in children and adolescents
    • American Diabetes Association
    • American Diabetes Association. Type 2 diabetes in children and adolescents. Pediatrics 2000; 105: 671-680
    • (2000) Pediatrics , vol.105 , pp. 671-680
  • 29
    • 0014242502 scopus 로고
    • Growth and physiological development during adolescence
    • Marshall WA, Tanner JM. Growth and physiological development during adolescence. Annu Rev Med 1968; 19: 283-300
    • (1968) Annu Rev Med , vol.19 , pp. 283-300
    • Marshall, W.A.1    Tanner, J.M.2
  • 30
    • 4043099245 scopus 로고    scopus 로고
    • Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels
    • Bonner A, Kratzsch J, Muller G et al. Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels. J Clin Endocrinol Metab 2004; 89: 4053-4061
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4053-4061
    • Bonner, A.1    Kratzsch, J.2    Muller, G.3
  • 31
    • 33645014132 scopus 로고    scopus 로고
    • Physiological and pathophysiological regulation of regional adipose tissue in the development of insulin resistance and type 2 diabetes
    • Rattarasarn C. Physiological and pathophysiological regulation of regional adipose tissue in the development of insulin resistance and type 2 diabetes. Acta Physiol (Oxf) 2006; 186: 87-101
    • (2006) Acta Physiol (Oxf) , vol.186 , pp. 87-101
    • Rattarasarn, C.1
  • 32
    • 4544263054 scopus 로고    scopus 로고
    • Adiponectin, insulin resistance, and C-reactive protein in postpubertal Asian Indian adolescents
    • Vikram NK, Misra A, Pandey RM, Dwivedi M, Luthra K. Adiponectin, insulin resistance, and C-reactive protein in postpubertal Asian Indian adolescents. Metabolism 2004; 53: 1336-1341
    • (2004) Metabolism , vol.53 , pp. 1336-1341
    • Vikram, N.K.1    Misra, A.2    Pandey, R.M.3    Dwivedi, M.4    Luthra, K.5
  • 33
    • 0031887701 scopus 로고    scopus 로고
    • Plasma leptin in children: Relationship to puberty, gender, body composition, insulin sensitivity, and energy expenditure
    • Arslanian S, Suprasongsin C, Kalhan SC et al. Plasma leptin in children: relationship to puberty, gender, body composition, insulin sensitivity, and energy expenditure. Metabolism 1998; 47: 309-312
    • (1998) Metabolism , vol.47 , pp. 309-312
    • Arslanian, S.1    Suprasongsin, C.2    Kalhan, S.C.3
  • 34
    • 1842856003 scopus 로고    scopus 로고
    • Plasma leptin is associated with insulin resistance independent of age, body mass index, fat mass, lipids, and pubertal development in nondiabetic adolescents
    • Huang KC, Lin RC, Kormas N et al. Plasma leptin is associated with insulin resistance independent of age, body mass index, fat mass, lipids, and pubertal development in nondiabetic adolescents. Int J Obes Relat Metab Disord 2004; 28: 470-475
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 470-475
    • Huang, K.C.1    Lin, R.C.2    Kormas, N.3
  • 35
    • 0036266897 scopus 로고    scopus 로고
    • Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans
    • Stefan N, Vozarova B, Funahashi T et al. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes 2002; 51: 1884-1888
    • (2002) Diabetes , vol.51 , pp. 1884-1888
    • Stefan, N.1    Vozarova, B.2    Funahashi, T.3
  • 36
    • 30044448374 scopus 로고    scopus 로고
    • Direct metabolic regulation in skeletal muscle and fat tissue by leptin: Implications for glucose and fatty acids homeostasis
    • Ceddia RB. Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis. Int J Obes (Lond) 2005; 29: 1175-1183
    • (2005) Int J Obes (Lond) , vol.29 , pp. 1175-1183
    • RB, C.1
  • 37
    • 0842331606 scopus 로고    scopus 로고
    • Leptin impairs insulin signaling in rat adipocytes
    • Perez C, Fernandez-Galaz C, Fernandez-Agullo T et al. Leptin impairs insulin signaling in rat adipocytes. Diabetes 2004; 53: 347-353
    • (2004) Diabetes , vol.53 , pp. 347-353
    • Perez, C.1    Fernandez-Galaz, C.2    Fernandez-Agullo, T.3
  • 38
    • 0033044994 scopus 로고    scopus 로고
    • Leptin suppression of insulin secretion and gene expression in human pancreatic islets: Implications for the development of adipogenic diabetes mellitus
    • Seufert J, Kieffer TJ, Leech CA et al. Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus. J Clin Endocrinol Metab 1999; 84: 670-676
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 670-676
    • Seufert, J.1    Kieffer, T.J.2    Leech, C.A.3
  • 39
    • 0842284789 scopus 로고    scopus 로고
    • Leptin effects on pancreatic beta-cell gene expression and function
    • Seufert J. Leptin effects on pancreatic beta-cell gene expression and function. Diabetes 2004; 53 (Suppl 1): S152-S158
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Seufert, J.1
  • 40
    • 0033974348 scopus 로고    scopus 로고
    • The adipoinsular axis: Effects of leptin on pancreatic beta-cells
    • Kieffer TJ, Habener JF. The adipoinsular axis: effects of leptin on pancreatic beta-cells. Am J Physiol Endocrinol Metab 2000; 278: E1-E14
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Kieffer, T.J.1    Habener, J.F.2
  • 41
    • 0036774234 scopus 로고    scopus 로고
    • Circulating soluble leptin receptor and free leptin index during childhood, puberty, and adolescence
    • Kratzsch J, Lammert A, Bottner A et al. Circulating soluble leptin receptor and free leptin index during childhood, puberty, and adolescence. J Clin Endocrinol Metab 2002; 87: 4587-4594
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4587-4594
    • Kratzsch, J.1    Lammert, A.2    Bottner, A.3
  • 42
    • 0030936047 scopus 로고    scopus 로고
    • The metabolic significance of leptin in humans: Gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure
    • Kennedy A, Gettys TW, Watson P et al. The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure. J Clin Endocrinol Metab 1997; 82: 1293-1300
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1293-1300
    • Kennedy, A.1    Gettys, T.W.2    Watson, P.3
  • 43
    • 0030754054 scopus 로고    scopus 로고
    • Effects of gender, ethnicity, body composition, and fat distribution on serum leptin concentrations in children
    • Nagy TR, Gower BA, Trowbridge CA et al. Effects of gender, ethnicity, body composition, and fat distribution on serum leptin concentrations in children. J Clin Endocrinol Metab 1997; 82: 2148-2152
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2148-2152
    • Nagy, T.R.1    Gower, B.A.2    Trowbridge, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.