Insulin resistance and associated compensatory responses in African-American and hispanic children

Diabetes Care

Volumn 25, Issue 12, 2002, Pages 2184-2190

  Goran, Michael I ^a   Bergman, Richard N ^a   Cruz, Martha L ^a   Watanabe, Richard ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN; FATTY ACID;

AFRICAN AMERICAN; ARTICLE; BODY FAT; CONTROLLED STUDY; ETHNIC DIFFERENCE; HISPANIC; HUMAN; INSULIN CLEARANCE; INSULIN RELEASE; INSULIN RESISTANCE; INTRAVENOUS GLUCOSE TOLERANCE TEST; NORMAL HUMAN; ADIPOSE TISSUE; BLOOD; CAUCASIAN; CHILD; COMPARATIVE STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HISTOLOGY; METABOLISM; PHYSIOLOGY; RADIODENSITOMETRY; REGRESSION ANALYSIS;

ADIPOSE TISSUE; AFRICAN AMERICANS; BLOOD GLUCOSE; C-PEPTIDE; CHILD; DENSITOMETRY, X-RAY; EUROPEAN CONTINENTAL ANCESTRY GROUP; FATTY ACIDS, NONESTERIFIED; GLUCOSE TOLERANCE TEST; HISPANIC AMERICANS; HUMANS; INSULIN; INSULIN RESISTANCE; LEAST-SQUARES ANALYSIS;

EID: 0037956818     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.25.12.2184     Document Type: Article

References (25)

1. National Diabetes Data Group: Diabetes in America. Washington, DC, National Institutes of Health, 1995
2. American Diabetes Association: Type 2 diabetes in children and adolescents. Pediatrics 105:671-680, 2000
3. Boyko EJ, Fujimoto WY, Leonetti DL, Newell-Morris LL: Visceral adiposity and risk of type 2 diabetes. Diabetes Care 23:465-472, 2000
4. Kahn SE: The importance of B-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 86:4047-4058, 2001
5. Goran MI, Gower BA: Longitudinal study of pubertal insulin resistance. Diabetes 50:2444-2450, 2001
6. Caprio S, Plewe G, Diamond MP, Simonson DC, Boulward SD, Sherwin RS, Tambolane V: Increased insulin secretion in puberty: a compensatory response to reductions in insulin sensitivity. J Pediatr 114:963-967, 1989
7. Freedman DS, Srinivasan SR, Burke GL, Shear CL, Smoak CG, Harsha DW, Webber LS, Berenson GS: Relation of body fat distribution to hyperinsulinemia in children and adolescents: the Bogalusa Heart Study. Am J Clin Nutr 46:403-410, 1987
8. Burke GL, Webber LS, Srinivasan SR, Radhakrishnamurthy B, Freedman DS, Berenson GS: Fasting plasma glucose and insulin levels and their relationship to cardiovascular risk factors in children: Bogalusa Heart Study. Metabolism 35:441-446, 1986
9. Gower BA, Nagy TR, Goran MI: Visceral fat, insulin sensitivity, and lipids in prepubertal children. Diabetes 48:1515-1521, 1999
10. Arslanian S, Suprasongsin C, Janosky JE: Insulin secretion and sensitivity in black versus white prepubertal healthy children. J Clin Endocrinol Metab 82:1923-1927, 1997
11. Goran MI: Metabolic precursors and effects of obesity in children: a decade of progress, 1990-1999. Am J Clin Nutr 73:158-171, 2001
12. Gower BA, Granger WM, Franklin F, Shewchuk RM, Goran MI: Contribution of insulin secretion and clearance to the greater acute insulin response to glucose in African-American vs Caucasian children and adolescents. J Clin Endocrinol Metab 87:2224, 2002
13. Haffner SM, D'Agostino RJ, Saad MF, Rewers M, Mykkanen L, Selby J: Increased insulin resistance and insulin secretion in non-diabetic African-Americans, and Hispanics compared to non-Hispanic whites: the Insulin Resistance Atherosclerosis Study. Diabetes 45:742-748, 1996
14. Haffner SM, Stern MP, Mitchell BD, Hazuda HP, Patterson JK: Incidence of type II diabetes in Mexican Americans predicted by fasting insulin and glucose levels, obesity and body-fat distribution. Diabetes 39:283-288, 1990
15. Haffner SM, Miettinen H, Gaskill SP, Stern MP: Decreased insulin secretion and increased insulin resistance are independently related to the 7-year risk of NIDDM in Mexican-Americans. Diabetes 44:1386-1391, 1995
16. Batey LS, Goff DC Jr, Tortolero SR, Nichaman MZ, Chan W, Chan FA, Grunbaum J, Hanis CL, Labarthe DR: Summary measures of the insulin resistance syndrome are adverse among Mexican-American versus non-Hispanic white children: the Corpus Christi Child Heart Study. Circulation 96:4319-4325, 1997
17. Watanabe RM, Steil GM, Bergman RN: Critical evaluation of the combined model approach for estimation of pre-hepatic insulin secretion. Am J Physiol 274:E172-E183, 1998
18. Van Cauter E, Mestrez F, Sturis J, Polonsky KS: Estimation of insulin secretion rates from C-peptide levels: comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41:368-377, 1992
19. Chiu KC, Cohan P, Lee NP, Chuang LM: Insulin sensitivity differs among ethnic groups with a compensatory response in B-cell function. Diabetes Care 23:1353-1358, 2000
20. Osei, K, Schuster, DP: Ethinic differences in secretion, sensivity, and hepatic extraction of insulin in black and white Americans. Diabet Med 11:755-762, 1994
21. Sinnett-Smith PA, Waddington D: Size distribution of adiposytes and variation in adiposyte number in lines of mice selected for high or low body fat. Comp Biochem Physiol B 102a:573-578, 1992
22. Mittelman SD, Citters AN, Gwim SP, Davis DA, Dea MK, Hamilton-Wessler M, Bergman RN: Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced B-cell response. Diabetes 49:2116-2125, 2000
23. Bergman RN: Toward physiological understanding of glucose tolerance. Diabetes 38:1512-1527, 1989
24. Arslanian S, Suprasongsin C: Difference in the in vivo secretion and sensitivity of healthy black versus white adolescents. J Pediatr 129:440-443, 1996
25. Gower BA, Herd SL, Goran MI: Anti-lipolytic effects of insulin in African American and white prepubertal boys. Obes Res 9:224-228, 2001