Conformational stability of human frataxin and effect of Friedreich's ataxia-related mutations on protein folding

Biochemical Journal

Volumn 398, Issue 3, 2006, Pages 605-611

  Correia, Ana R ^a   Adinolfi, Salvatore ^b   Pastore, Annalisa ^b   Gomes, Cláudio M ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Frataxin; Friedreich's ataxia (FRDA); Iron binding protein; Protein folding; Trinucleotide expansion

Indexed keywords

BINDING ENERGY; GENETIC ENGINEERING; MUTAGENESIS; PATHOLOGY; PROTEINS; THERMODYNAMIC STABILITY;

FRATAXIN; FRIEDREICH'S ATAXIA (FRDA); IRON BINDING PROTEIN; PROTEIN FOLDING; TRINUCLEOTIDE EXPANSION;

NEUROLOGY;

FRATAXIN; IRON BINDING PROTEIN;

ARTICLE; FRIEDREICH ATAXIA; IRON BINDING CAPACITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN STRUCTURE; THERMODYNAMICS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN CONFORMATION;

ATAXIA;

ENZYME STABILITY; FRIEDREICH ATAXIA; HUMANS; IRON-BINDING PROTEINS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; THERMODYNAMICS;

EID: 33748745306     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060345     Document Type: Article

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