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Volumn 295, Issue 1, 2008, Pages

Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit

Author keywords

Pelvic nerve; Rats; Spinal cord; Urethra

Indexed keywords

1 (6,8 DIFLUORO 2 METHYL 4 QUINOLINYL) 3 (4 DIMETHYLAMINOPHENYL)UREA; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; OREXIN A; UNCLASSIFIED DRUG; 4 (3 PHOSPHONOALLYL) 2 PIPERAZINECARBOXYLIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; NEUROPEPTIDE; NR2B NMDA RECEPTOR; OREXINS; PD 174494; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; SIGNAL PEPTIDE;

EID: 50349087573     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90243.2008     Document Type: Article
Times cited : (22)

References (83)
  • 2
    • 0038094511 scopus 로고    scopus 로고
    • Orexin-A (hypocretin-1) impairs Morris water maze performance and CA1-Schaffer collateral long-term potentiation in rats
    • Aou S, Li XL, Li AJ, Oomura Y, Shiraishi T, Sasaki K, Imamura T, Wayner MJ. Orexin-A (hypocretin-1) impairs Morris water maze performance and CA1-Schaffer collateral long-term potentiation in rats. Neuroscience 119: 1221-1228, 2003.
    • (2003) Neuroscience , vol.119 , pp. 1221-1228
    • Aou, S.1    Li, X.L.2    Li, A.J.3    Oomura, Y.4    Shiraishi, T.5    Sasaki, K.6    Imamura, T.7    Wayner, M.J.8
  • 3
    • 2442558400 scopus 로고    scopus 로고
    • Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area
    • Bartsch T, Levy MJ, Knight YE, Goadsby PJ. Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area. Pain 109: 367-378, 2004.
    • (2004) Pain , vol.109 , pp. 367-378
    • Bartsch, T.1    Levy, M.J.2    Knight, Y.E.3    Goadsby, P.J.4
  • 4
    • 0012284221 scopus 로고
    • Presynaptic mechanism for long-term potentiation in the hippocampus
    • Bekkers JM, Stevens CF. Presynaptic mechanism for long-term potentiation in the hippocampus. Nature 349: 156-158, 1990.
    • (1990) Nature , vol.349 , pp. 156-158
    • Bekkers, J.M.1    Stevens, C.F.2
  • 6
    • 22544450154 scopus 로고    scopus 로고
    • Berberich S, Punnakkal P, Jensen V, Pawlak V, Seeburg PH, Hvalby O, Köhr G. Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J Neurosci 25: 6907-6910, 2005.
    • Berberich S, Punnakkal P, Jensen V, Pawlak V, Seeburg PH, Hvalby O, Köhr G. Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J Neurosci 25: 6907-6910, 2005.
  • 7
    • 0027280380 scopus 로고
    • The lateral hypothalamic area revisited: Neuroanatomy, body weight regulation, neuroendocrinology, and metabolism
    • Bernardis LL, Bellinger LL. The lateral hypothalamic area revisited: neuroanatomy, body weight regulation, neuroendocrinology, and metabolism. Neurosci Biobehav Rev 17: 141-193, 1993.
    • (1993) Neurosci Biobehav Rev , vol.17 , pp. 141-193
    • Bernardis, L.L.1    Bellinger, L.L.2
  • 8
    • 0029759523 scopus 로고    scopus 로고
    • The lateral hypothalamic area revisited: Ingestive behavior
    • Bernardis LL, Bellinger LL. The lateral hypothalamic area revisited: ingestive behavior. Neurosci Biobehav Rev 20: 189-287, 1996.
    • (1996) Neurosci Biobehav Rev , vol.20 , pp. 189-287
    • Bernardis, L.L.1    Bellinger, L.L.2
  • 10
    • 32344446144 scopus 로고    scopus 로고
    • Orexin A in the VTA is critical for the induction of synaptic plasticity, and behavioral sensitization to cocaine
    • Borgland SL, Taha SA, Sarti F, Fields HL, Bonci A. Orexin A in the VTA is critical for the induction of synaptic plasticity, and behavioral sensitization to cocaine. Neuron 49: 589-601, 2006.
    • (2006) Neuron , vol.49 , pp. 589-601
    • Borgland, S.L.1    Taha, S.A.2    Sarti, F.3    Fields, H.L.4    Bonci, A.5
  • 11
    • 0032987252 scopus 로고    scopus 로고
    • Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: Correlation with restricted localisation of NR2B subunit in dorsal horn
    • Boyce S, Wyatt A, Webb JK, O'Donnell R, Mason G, Rigby M, Sirinathsinghji D, Hill RG, Rupniak NM. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology 38: 611-623, 1999.
    • (1999) Neuropharmacology , vol.38 , pp. 611-623
    • Boyce, S.1    Wyatt, A.2    Webb, J.K.3    O'Donnell, R.4    Mason, G.5    Rigby, M.6    Sirinathsinghji, D.7    Hill, R.G.8    Rupniak, N.M.9
  • 12
    • 30844462124 scopus 로고    scopus 로고
    • Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation
    • Caudle RM, Perez FM, Del Valle-Pinero AY, Iadarola MJ. Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation. Mol Pain 2: 1-25, 2005.
    • (2005) Mol Pain , vol.2 , pp. 1-25
    • Caudle, R.M.1    Perez, F.M.2    Del Valle-Pinero, A.Y.3    Iadarola, M.J.4
  • 15
    • 32344441882 scopus 로고    scopus 로고
    • Effects of a calcineurin inhibitor, tacrolimus (FK-506), on glutamate dependent potentiation in pelvic-urethral reflex in anesthetized rats
    • Chen KJ, Chen LW, Liao JM, Chen CH, Ho YC, Ho YC, Cheng CL, Lin JJ, Huang PC, Lin TB. Effects of a calcineurin inhibitor, tacrolimus (FK-506), on glutamate dependent potentiation in pelvic-urethral reflex in anesthetized rats. Neuroscience 138: 69-76, 2006.
    • (2006) Neuroscience , vol.138 , pp. 69-76
    • Chen, K.J.1    Chen, L.W.2    Liao, J.M.3    Chen, C.H.4    Ho, Y.C.5    Ho, Y.C.6    Cheng, C.L.7    Lin, J.J.8    Huang, P.C.9    Lin, T.B.10
  • 16
    • 33847770774 scopus 로고    scopus 로고
    • Acute unilateral ureter distension inhibits glutamate-dependent spinal pelvic-urethra reflex potentiation via GABAergic neurotransmission in anesthetized rats
    • Chen KJ, Peng HY, Cheng CL, Chen CH, Liao JM, Ho YC, Liou JD, Tung KC, Hsu TH, Lin TB. Acute unilateral ureter distension inhibits glutamate-dependent spinal pelvic-urethra reflex potentiation via GABAergic neurotransmission in anesthetized rats. Am J Physiol Renal Physiol 292: F1007-F1015, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Chen, K.J.1    Peng, H.Y.2    Cheng, C.L.3    Chen, C.H.4    Liao, J.M.5    Ho, Y.C.6    Liou, J.D.7    Tung, K.C.8    Hsu, T.H.9    Lin, T.B.10
  • 17
    • 0344304799 scopus 로고    scopus 로고
    • Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain
    • Cheng JK, Chou RCC, Hwang LL, Chiou LC. Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain. J Pharmacol Exp Ther 307: 1065-1071, 2003.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 1065-1071
    • Cheng, J.K.1    Chou, R.C.C.2    Hwang, L.L.3    Chiou, L.C.4
  • 18
    • 0037086842 scopus 로고    scopus 로고
    • Protein distribution of the orexin-2 receptor in the rat central nervous system
    • Cluderay JE, Harrison DC, Hervieu GJ. Protein distribution of the orexin-2 receptor in the rat central nervous system. Regul Pept 104: 131-144, 2002.
    • (2002) Regul Pept , vol.104 , pp. 131-144
    • Cluderay, J.E.1    Harrison, D.C.2    Hervieu, G.J.3
  • 19
    • 0025338354 scopus 로고
    • Excitatory amino acid receptors and synaptic plasticity
    • Collingridge GL, Singer W. Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol Sci 11: 290-296, 1990.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 290-296
    • Collingridge, G.L.1    Singer, W.2
  • 20
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy S, Brickley S, Farrant M. NMDA receptor subunits: diversity, development and disease. Curr Opin Neurobiol 11: 327-335, 2001.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 24
    • 0032863991 scopus 로고    scopus 로고
    • Food intake elicited by central administration of orexins/hypocretins: Identification of hypothalamic sites of action
    • Dube MG, Kalra SP, Kalra PS. Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action. Brain Res 842: 473-477, 1999.
    • (1999) Brain Res , vol.842 , pp. 473-477
    • Dube, M.G.1    Kalra, S.P.2    Kalra, P.S.3
  • 25
    • 0036139881 scopus 로고    scopus 로고
    • LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1
    • Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5: 27-33, 2002.
    • (2002) Nat Neurosci , vol.5 , pp. 27-33
    • Grosshans, D.R.1    Clayton, D.A.2    Coultrap, S.J.3    Browning, M.D.4
  • 26
    • 0036554701 scopus 로고    scopus 로고
    • Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn
    • Grudt TJ, Perl ER. Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. J Physiol 540: 189-207, 2002.
    • (2002) J Physiol , vol.540 , pp. 189-207
    • Grudt, T.J.1    Perl, E.R.2
  • 27
    • 0037082239 scopus 로고    scopus 로고
    • Hypocretin-2 (orexin-B) modulation of superficial dorsal horn activity in rat
    • Grudt TJ, van der Pol AN, Perl ER. Hypocretin-2 (orexin-B) modulation of superficial dorsal horn activity in rat. J Physiol 538: 517-525, 2002.
    • (2002) J Physiol , vol.538 , pp. 517-525
    • Grudt, T.J.1    van der Pol, A.N.2    Perl, E.R.3
  • 28
    • 0022483393 scopus 로고
    • Hippocampal long-lasting potentiation produced by pairing single volleys and brief conditioning tetani evoked in separated afferents
    • Gustafsson B, Wigström H. Hippocampal long-lasting potentiation produced by pairing single volleys and brief conditioning tetani evoked in separated afferents. J Neurosci 6: 1575-1582, 1986.
    • (1986) J Neurosci , vol.6 , pp. 1575-1582
    • Gustafsson, B.1    Wigström, H.2
  • 29
    • 33748806552 scopus 로고    scopus 로고
    • Arousal and reward: A dichotomy in orexin function
    • Harris GC, Aston-Jones G. Arousal and reward: a dichotomy in orexin function. Trends Neurosci 29: 571-577, 2006.
    • (2006) Trends Neurosci , vol.29 , pp. 571-577
    • Harris, G.C.1    Aston-Jones, G.2
  • 30
    • 0035925698 scopus 로고    scopus 로고
    • Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord
    • Hervieu GJ, Cluderay JE, Harrison DC, Roberts JC, Leslie RA. Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord. Neuroscience 103: 777-797, 2001.
    • (2001) Neuroscience , vol.103 , pp. 777-797
    • Hervieu, G.J.1    Cluderay, J.E.2    Harrison, D.C.3    Roberts, J.C.4    Leslie, R.A.5
  • 31
    • 27744547515 scopus 로고    scopus 로고
    • Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception
    • Holland PR, Akerman S, Goadsby PJ. Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception. J Pharmacol Exp Ther 315: 1380-1385, 2005.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1380-1385
    • Holland, P.R.1    Akerman, S.2    Goadsby, P.J.3
  • 32
    • 35148843318 scopus 로고    scopus 로고
    • Responses of hypothalamic orexin-containing neurons to cyclophosphamide, EHF irradiation of the skin, and their combination in rats
    • Holland P, Goadsby PJ. Responses of hypothalamic orexin-containing neurons to cyclophosphamide, EHF irradiation of the skin, and their combination in rats. Pathophysiology 14: 79-85, 2007.
    • (2007) Pathophysiology , vol.14 , pp. 79-85
    • Holland, P.1    Goadsby, P.J.2
  • 33
    • 0033490464 scopus 로고    scopus 로고
    • Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity
    • Ji RR, Baba H, Brenner GJ, Woolf CJ. Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2: 1114-1119, 1999.
    • (1999) Nat Neurosci , vol.2 , pp. 1114-1119
    • Ji, R.R.1    Baba, H.2    Brenner, G.J.3    Woolf, C.J.4
  • 34
    • 0037080003 scopus 로고    scopus 로고
    • ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity
    • Ji RR, Befort K, Brenner GJ, Woolf CJ. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J Neurosci 22: 478-485, 2002.
    • (2002) J Neurosci , vol.22 , pp. 478-485
    • Ji, R.R.1    Befort, K.2    Brenner, G.J.3    Woolf, C.J.4
  • 35
    • 0242475309 scopus 로고    scopus 로고
    • Central sensitization and long-term potentiation-do pain and memory share similar mechanisms?
    • Ji RR, Kohno T, Moore KA, Woolf CJ. Central sensitization and long-term potentiation-do pain and memory share similar mechanisms? Trends Neurosci 26: 696-705, 2003.
    • (2003) Trends Neurosci , vol.26 , pp. 696-705
    • Ji, R.R.1    Kohno, T.2    Moore, K.A.3    Woolf, C.J.4
  • 36
    • 0037705314 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • Jin SX, Zhuang ZY, Woolf CJ, Ji RR. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci 23: 4017-4022, 2003.
    • (2003) J Neurosci , vol.23 , pp. 4017-4022
    • Jin, S.X.1    Zhuang, Z.Y.2    Woolf, C.J.3    Ji, R.R.4
  • 37
    • 18144427915 scopus 로고    scopus 로고
    • Spinal orexin-1 receptors mediate anti-hyperalgesic effects of intrathecally-administered orexins in diabetic neuropathic pain model rats
    • Kajiyama S, Kawamoto M, Shiraishi S, Gaus S, Matsunaga A, Suyama H, Yuge O. Spinal orexin-1 receptors mediate anti-hyperalgesic effects of intrathecally-administered orexins in diabetic neuropathic pain model rats. Brain Res 1044: 76-86, 2005.
    • (2005) Brain Res , vol.1044 , pp. 76-86
    • Kajiyama, S.1    Kawamoto, M.2    Shiraishi, S.3    Gaus, S.4    Matsunaga, A.5    Suyama, H.6    Yuge, O.7
  • 38
    • 0023677162 scopus 로고
    • NMDA application potentiates synaptic transmission in the hippocampus
    • Kauer JA, Malenka RC, Nicoll RA. NMDA application potentiates synaptic transmission in the hippocampus. Nature 334: 250-252, 1988.
    • (1988) Nature , vol.334 , pp. 250-252
    • Kauer, J.A.1    Malenka, R.C.2    Nicoll, R.A.3
  • 39
    • 4644312225 scopus 로고    scopus 로고
    • Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization
    • Kawasaki K, Kohno T, Zhuang ZY, Brenner GJ, Wang H, Van Der Meer C, Befort K, Woolf CJ, Ji RR. Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. J Neurosci 24: 8310-8321, 2004.
    • (2004) J Neurosci , vol.24 , pp. 8310-8321
    • Kawasaki, K.1    Kohno, T.2    Zhuang, Z.Y.3    Brenner, G.J.4    Wang, H.5    Van Der Meer, C.6    Befort, K.7    Woolf, C.J.8    Ji, R.R.9
  • 40
    • 4444360964 scopus 로고    scopus 로고
    • NR2B receptors are involved in the mediation of spinal segmental reflex potentials but not in the cumulative motoneuronal depolarization in vitro
    • Kocsis P, Kovacs G, Farkas S, Horvath C, Szombathelyi Z, Tarnawa I. NR2B receptors are involved in the mediation of spinal segmental reflex potentials but not in the cumulative motoneuronal depolarization in vitro. Brain Res Bull 64: 133-138, 2004.
    • (2004) Brain Res Bull , vol.64 , pp. 133-138
    • Kocsis, P.1    Kovacs, G.2    Farkas, S.3    Horvath, C.4    Szombathelyi, Z.5    Tarnawa, I.6
  • 41
    • 34547147059 scopus 로고    scopus 로고
    • Experience-dependent changes in NMDA receptor composition at mature central synapses
    • Kopp C, Longordo F, Luthi A. Experience-dependent changes in NMDA receptor composition at mature central synapses. Neuropharmacology 53: 1-9, 2007.
    • (2007) Neuropharmacology , vol.53 , pp. 1-9
    • Kopp, C.1    Longordo, F.2    Luthi, A.3
  • 45
    • 0037079062 scopus 로고    scopus 로고
    • Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD
    • Lee SH, Liu L, Wang YT, Sheng M. Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD. Neuron 36: 661-674, 2002.
    • (2002) Neuron , vol.36 , pp. 661-674
    • Lee, S.H.1    Liu, L.2    Wang, Y.T.3    Sheng, M.4
  • 46
    • 13244276921 scopus 로고    scopus 로고
    • Spastic long-lasting reflexes of the chronic spinal rat studied in vitro
    • Li Y, Harvey PJ, Li X, Bennett DJ. Spastic long-lasting reflexes of the chronic spinal rat studied in vitro. J Neurophysiol 91: 2236-2246, 2004.
    • (2004) J Neurophysiol , vol.91 , pp. 2236-2246
    • Li, Y.1    Harvey, P.J.2    Li, X.3    Bennett, D.J.4
  • 50
    • 0037292991 scopus 로고    scopus 로고
    • Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats
    • Lin TB. Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats. Neuropharmacology 44: 163-170, 2003.
    • (2003) Neuropharmacology , vol.44 , pp. 163-170
    • Lin, T.B.1
  • 51
    • 3242704206 scopus 로고    scopus 로고
    • Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rat
    • Lin TB. Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rat. Am J Physiol Renal Physiol 287: F245-F251, 2004.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Lin, T.B.1
  • 53
    • 1842372050 scopus 로고    scopus 로고
    • Characterization of long-term potentiation of C-fiber-evoked potentials in spinal dorsal horn of adult rat: Essential role of NK1 and NK2 receptors
    • Liu XG, Sandkuhler J. Characterization of long-term potentiation of C-fiber-evoked potentials in spinal dorsal horn of adult rat: essential role of NK1 and NK2 receptors. J Neurophysiol 78: 1973-1982, 1997.
    • (1997) J Neurophysiol , vol.78 , pp. 1973-1982
    • Liu, X.G.1    Sandkuhler, J.2
  • 54
    • 0029040001 scopus 로고
    • Long-term potentiation of C-fiber-evoked potentials in the rat spinal dorsal horn is prevented by spinal N-methyl-D-aspartic acid receptor blockage
    • Liu XG, Sandkuhler J. Long-term potentiation of C-fiber-evoked potentials in the rat spinal dorsal horn is prevented by spinal N-methyl-D-aspartic acid receptor blockage. Neurosci Lett 191: 43-46, 1995.
    • (1995) Neurosci Lett , vol.191 , pp. 43-46
    • Liu, X.G.1    Sandkuhler, J.2
  • 55
    • 33846904031 scopus 로고    scopus 로고
    • Spatic tail muscles recover from myofiber atrophy and myosin heavy chan transformations in chronic spinal rat
    • Luke R, Harris W, Putman CT, Rank M, Sanelli L, Bennett DJ. Spatic tail muscles recover from myofiber atrophy and myosin heavy chan transformations in chronic spinal rat. J Neurophysiol 97: 1040-1051, 2007.
    • (2007) J Neurophysiol , vol.97 , pp. 1040-1051
    • Luke, R.1    Harris, W.2    Putman, C.T.3    Rank, M.4    Sanelli, L.5    Bennett, D.J.6
  • 56
    • 0028143759 scopus 로고
    • Alternatively spliced isoforms of the N-methyl-D-aspartate receptor subunit 1 are differentially distributed within the rat spinal cord
    • Luque JM, Bleuel Z, Malherbe P, Richards JG. Alternatively spliced isoforms of the N-methyl-D-aspartate receptor subunit 1 are differentially distributed within the rat spinal cord. Neuroscience 63: 629-635, 1994.
    • (1994) Neuroscience , vol.63 , pp. 629-635
    • Luque, J.M.1    Bleuel, Z.2    Malherbe, P.3    Richards, J.G.4
  • 59
    • 33845872541 scopus 로고    scopus 로고
    • Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression
    • Morishita W, Lu W, Smith GB, Nicoll RA, Bear MF, Malenka RC. Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Neuropharmacology 52: 71-76, 2007.
    • (2007) Neuropharmacology , vol.52 , pp. 71-76
    • Morishita, W.1    Lu, W.2    Smith, G.B.3    Nicoll, R.A.4    Bear, M.F.5    Malenka, R.C.6
  • 61
    • 0037509894 scopus 로고    scopus 로고
    • Excitatory effects of hypocretin-1 (orexin-A) in the trigeminal motor nucleus are reversed by NMDA antagonism
    • Peever JH, Lai YY, Siegel JM. Excitatory effects of hypocretin-1 (orexin-A) in the trigeminal motor nucleus are reversed by NMDA antagonism. J Neurophysiol 89: 2591-2600, 2003.
    • (2003) J Neurophysiol , vol.89 , pp. 2591-2600
    • Peever, J.H.1    Lai, Y.Y.2    Siegel, J.M.3
  • 63
    • 0028087773 scopus 로고
    • The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
    • Petralia RS, Wang YX, Wenthold RJ. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J Neurosci 14: 6102-6120, 1994.
    • (1994) J Neurosci , vol.14 , pp. 6102-6120
    • Petralia, R.S.1    Wang, Y.X.2    Wenthold, R.J.3
  • 65
    • 1642398017 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptors: Subunit assembly and trafficking to the synapse
    • Prybylowski K, Wenthold RJ. N-methyl-D-aspartate receptors: subunit assembly and trafficking to the synapse. J Biol Chem 279: 9673-9676, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 9673-9676
    • Prybylowski, K.1    Wenthold, R.J.2
  • 67
    • 3242738450 scopus 로고    scopus 로고
    • Orexins/hypocretins cause sharp wave and -related synaptic plasticity in the hippocampus via glutamatergic, GABAergic, noradrenergic, and cholinergic signaling
    • Selbach O, Doreulee N, Bohla C, Eriksson KS, Sergeeva OA, Poelchen W, Brown RE, Haas HL. Orexins/hypocretins cause sharp wave and -related synaptic plasticity in the hippocampus via glutamatergic, GABAergic, noradrenergic, and cholinergic signaling. Neuroscience 127: 519-528, 2004.
    • (2004) Neuroscience , vol.127 , pp. 519-528
    • Selbach, O.1    Doreulee, N.2    Bohla, C.3    Eriksson, K.S.4    Sergeeva, O.A.5    Poelchen, W.6    Brown, R.E.7    Haas, H.L.8
  • 68
    • 0034851590 scopus 로고    scopus 로고
    • Subunit characterization of NMDA receptors
    • Stephenson FA. Subunit characterization of NMDA receptors. Curr Drug Targets 2: 233-239, 2001.
    • (2001) Curr Drug Targets , vol.2 , pp. 233-239
    • Stephenson, F.A.1
  • 69
    • 33645105536 scopus 로고    scopus 로고
    • Subunit dependencies of N-methyl-D-aspartate (NMDA) receptor-induced alpha-amino-3-hydroxy-5-methyl-4-isox-azolepropionic acid (AMPA) receptor internalization
    • Tigaret CM, Thalhammer A, Rast GF, Specht CG, Auberson YP, Stewart MG, Schoepfer R. Subunit dependencies of N-methyl-D-aspartate (NMDA) receptor-induced alpha-amino-3-hydroxy-5-methyl-4-isox-azolepropionic acid (AMPA) receptor internalization. Mol Pharmacol 69: 1251-1259, 2006.
    • (2006) Mol Pharmacol , vol.69 , pp. 1251-1259
    • Tigaret, C.M.1    Thalhammer, A.2    Rast, G.F.3    Specht, C.G.4    Auberson, Y.P.5    Stewart, M.G.6    Schoepfer, R.7
  • 70
    • 0027141312 scopus 로고
    • The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray
    • Tolle TR, Berthele A, Zieglgansberger W, Seeburg PH, Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J Neurosci 13: 5009-5028, 1993.
    • (1993) J Neurosci , vol.13 , pp. 5009-5028
    • Tolle, T.R.1    Berthele, A.2    Zieglgansberger, W.3    Seeburg, P.H.4    Wisden, W.5
  • 71
    • 33645640329 scopus 로고    scopus 로고
    • Uterine cervical afferents in thoracolumbar dorsal root ganglia express transient receptor potential vanilloid type 1 channel and calcitonin gene-related peptide but not P2X3 receptor and somatostatin
    • Tong C, Conklin D, Clyne BB, Stanislaus JK, Eisenach JC. Uterine cervical afferents in thoracolumbar dorsal root ganglia express transient receptor potential vanilloid type 1 channel and calcitonin gene-related peptide but not P2X3 receptor and somatostatin. Anesthesiology 104: 651-657, 2006.
    • (2006) Anesthesiology , vol.104 , pp. 651-657
    • Tong, C.1    Conklin, D.2    Clyne, B.B.3    Stanislaus, J.K.4    Eisenach, J.C.5
  • 73
    • 33646087668 scopus 로고    scopus 로고
    • Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat
    • Ultenius C, Linderoth B, Meyerson BA, Wallin J. Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat. Neurosci Lett 399: 85-90, 2006.
    • (2006) Neurosci Lett , vol.399 , pp. 85-90
    • Ultenius, C.1    Linderoth, B.2    Meyerson, B.A.3    Wallin, J.4
  • 74
    • 0033561178 scopus 로고    scopus 로고
    • Hypothalamic hypocretin (orexin): Robust innervation of the spinal cord
    • van den Pol AN. Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J Neurosci 19: 3171-3182, 1999.
    • (1999) J Neurosci , vol.19 , pp. 3171-3182
    • van den Pol, A.N.1
  • 75
    • 0030916208 scopus 로고    scopus 로고
    • Lateral hypothalamic stimulation inhibits dentate granule cell LTP: Direct connections
    • Wayner MJ, Phelix CF, Armstrong DL. Lateral hypothalamic stimulation inhibits dentate granule cell LTP: direct connections. Brain Res Bull 43: 5-15, 1997.
    • (1997) Brain Res Bull , vol.43 , pp. 5-15
    • Wayner, M.J.1    Phelix, C.F.2    Armstrong, D.L.3
  • 76
    • 0021014399 scopus 로고
    • Evidence for a central component of post-injury pain hypersensitivity
    • Woolf CJ. Evidence for a central component of post-injury pain hypersensitivity. Nature 306: 686-688, 1983.
    • (1983) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 77
    • 0025819935 scopus 로고
    • Generation of acute pain: Central mechanisms
    • Woolf CJ. Generation of acute pain: central mechanisms. Br Med Bull 47: 523-533, 1991.
    • (1991) Br Med Bull , vol.47 , pp. 523-533
    • Woolf, C.J.1
  • 78
    • 34248211147 scopus 로고    scopus 로고
    • Central sensitization: Uncovering the relation between pain and plasticity
    • Woolf CJ. Central sensitization: uncovering the relation between pain and plasticity. Anesthesiology 106: 864-867, 2007.
    • (2007) Anesthesiology , vol.106 , pp. 864-867
    • Woolf, C.J.1
  • 79
    • 0025974775 scopus 로고
    • The induction and maintainance of central sensitization is dependent on N-methyl-D-aspartatic acid receptor activation: Implications for the treatment of post-injury pain hypersensitivity states
    • Woolf CJ, Thompson SW. The induction and maintainance of central sensitization is dependent on N-methyl-D-aspartatic acid receptor activation: implications for the treatment of post-injury pain hypersensitivity states. Pain 44: 293-299, 1991.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.2
  • 80
    • 0036740492 scopus 로고    scopus 로고
    • Analgesic effect of intrathecally administered orexin-A in the rat formalin test and in the rat hot plate test
    • Yamamoto T, Nozaki-Taguchi N, Chiba T. Analgesic effect of intrathecally administered orexin-A in the rat formalin test and in the rat hot plate test. Br J Pharmacol 137: 170-176, 2002.
    • (2002) Br J Pharmacol , vol.137 , pp. 170-176
    • Yamamoto, T.1    Nozaki-Taguchi, N.2    Chiba, T.3
  • 81
    • 0043091918 scopus 로고    scopus 로고
    • Anti-mechanical allodynic effect of intrathecal and intracerebroventricular injection of orexin-A in the rat neuropathic pain model
    • Yamamoto T, Saito O, Shono K, Aoe T, Chiba T. Anti-mechanical allodynic effect of intrathecal and intracerebroventricular injection of orexin-A in the rat neuropathic pain model. Neurosci Lett 347: 183-186, 2003.
    • (2003) Neurosci Lett , vol.347 , pp. 183-186
    • Yamamoto, T.1    Saito, O.2    Shono, K.3    Aoe, T.4    Chiba, T.5
  • 82
    • 34247550637 scopus 로고    scopus 로고
    • Estrogen amplifies pain response to uterine cervical distension in rats by altering transient receptor potential-1 function
    • Yan T, Liu B, Du D, Eisenach JC, Tong C. Estrogen amplifies pain response to uterine cervical distension in rats by altering transient receptor potential-1 function. Anesth Analg 104: 1246-1250, 2007.
    • (2007) Anesth Analg , vol.104 , pp. 1246-1250
    • Yan, T.1    Liu, B.2    Du, D.3    Eisenach, J.C.4    Tong, C.5
  • 83
    • 0032507588 scopus 로고    scopus 로고
    • Localization of glutamate receptors in dorsal horn of rat spinal cord
    • Yung KK. Localization of glutamate receptors in dorsal horn of rat spinal cord. Neuroreport 9: 1639-1644, 1998.
    • (1998) Neuroreport , vol.9 , pp. 1639-1644
    • Yung, K.K.1


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