Subunit dependencies of N-Methyl-D-aspartate (NMDA) receptor-induced α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization

Molecular Pharmacology

Volumn 69, Issue 4, 2006, Pages 1251-1259

  Tigaret, C M ^a   Thalhammer, A ^a   Rast, G F ^a   Specht, C G ^a,d   Auberson, Y P ^b   Stewart, M G ^c   Schoepfer, R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NOVARTIS PHARMA AG   (Switzerland)

^c OPEN UNIVERSITY   (United Kingdom)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; CALCIUM; GLUTAMATE RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CALCIUM BLOOD LEVEL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOCYTOSIS; HIPPOCAMPUS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; ENDOCYTOSIS; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; MICE; NEURONS; PHENOTYPE; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 33645105536     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.018580     Document Type: Article

References (40)

1. Auberson YP, Allgeier H, Bischoff S, Lingenhoehl K, Moretti R, and Schmutz M (2002) 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett 12:1099-1102.
2. Augustine GJ, Santamaria F, and Tanaka K (2003) Local calcium signaling in neurons. Neuron 40:331-346.
3. Beattie EC, Carroll RC, Yu X, Morishita W, Yasuda H, von Zastrow M, and Malenka RC (2000) Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nat Neurosci 3:1291-1300.
4. Berberich S, Punnakkal P, Jensen V, Pawlak V, Seeburg PH, Hvalby O, and Kohr G (2005) Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J Neurosci 25:6907-6910.
5. Burnashev N, Zhou Z, Neher E, and Sakmann B (1995) Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J Physiol 485 (Pt 2):403-418.
6. Collingridge GL, Isaac JT, and Wang YT (2004) Receptor trafficking and synaptic plasticity. Nat Rev Neurosci 5:952-962.
7. Dingledine R, Borges K, Bowie D, and Traynelis SF (1999) The glutamate receptor ion channels. Pharmacol Rev 51:7-61.
8. Fischer G, Mutel V, Trube G, Malherbe P, Kew JN, Mohacsi E, Heitz MP, and Kemp JA (1997) Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. J Pharmacol Exp Ther 283:1285-1292.
9. Hayashi Y, Shi SH, Esteban JA, Piccini A, Poncer JC, and Malinow R (2000) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science (Wash DC) 287:2262-2267.
10. Husi H, Ward MA, Choudhary JS, Blackstock WP, and Grant SG (2000) Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat Neurosci 3:661-669.
11. Jia Z, Agopyan N, Miu P, Xiong Z, Henderson J, Gerlai R, Taverna FA, Velumian A, MacDonald J, Carlen P, et al. (1996) Enhanced LTP in mice deficient in the AMPA receptor GluR2. Neuron 17:945-956.
12. Keinanen K, Wisden W, Sommer B, Werner P, Herb A, Verdoorn TA, Sakmann B, and Seeburg PH (1990) A family of AMPA-selective glutamate receptors. Science (Wash DC) 249:556-560.
13. Kew JN, Richards JG, Mutel V, and Kemp JA (1998) Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons. J Neurosci 18:1935-1943.
14. Kim J, Dittgen T, Nimmerjahn A, Waters J, Pawlak V, Helmchen F, Schlesinger S, Seeburg PH, and Osten P (2004) Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons. J Neurosci Methods 133:81-90.
15. Kim MJ, Dunah AW, Wang YT, and Sheng M (2005) differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking. Neuron 46:745-760.
16. Kohler M, Kornau HC, and Seeburg PH (1994) The organization of the gene for the functionally dominant α-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor subunit GluR-B. J Biol Chem 269:17367-17370.
17. Kolleker A, Zhu JJ, Schupp BJ, Qin Y, Mack V, Borchardt T, Kohr G, Malinow R, Seeburg PH, and Osten P (2003) Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors. Neuron 40:1199-1212.
18. Lee SH, Simonetta A, and Sheng M (2004) Subunit rules governing the sorting of internalized AMPA receptors in hippocampal neurons. Neuron 43:221-236.
19. Li B, Chen N, Luo T, Otsu Y, Murphy TH, and Raymond LA (2002) Differential regulation of synaptic and extra-synaptic NMDA receptors. Nat Neurosci 5:833-834.
20. Li JH, Wang YH, Wolfe BB, Krueger KE, Corsi L, Stocca G, and Vicini S (1998) Developmental changes in localization of NMDA receptor subunits in primary cultures of cortical neurons. Eur J Neurosci 10:1704-1715.
21. Lisman J (1989) A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc Natl Acad Sci USA 86:9574-9578.
22. Liu L, Wong TP, Pozza MF, Lingenhoehl K, Wang Y, Sheng M, Auberson YP, and Wang YT (2004) Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science (Wash DC) 304:1021-1024.
23. Luo J, Wang Y, Yasuda RP, Dunah AW, and Wolfe BB (1997) The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B). Mol Pharmacol 51:79-86.
24. Malenka RC and Bear MF (2004) LTP and LTD: an embarrassment of riches. Neuron 44:5-21.
25. Massey PV, Johnson BE, Moult PR, Auberson YP, Brown MW, Molnar E, Collingridge GL, and Bashir ZI (2004) Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. J Neurosci 24:7821-7828.
26. Monyer H, Burnashev N, Laurie DJ, Sakmann B, and Seeburg PH (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12:529-540.
27. Rudhard Y, Kneussel M, Nassar MA, Rast GF, Annala AJ, Chen PE, Tigaret CM, Dean I, Roes J, Gibb AJ, et al. (2003) Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling. J Neurosci 23:2323-2332.
28. Sheng M and Kim MJ (2002) Postsynaptic signaling and plasticity mechanisms. Science (Wash DC) 298:776-780.
29. Shi S, Hayashi Y, Esteban JA, and Malinow R (2001) Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell 105:331-343.
30. Shi SH, Hayashi Y, Petralia RS, Zaman SH, Wenthold RJ, Svoboda K, and Malinow R (1999) Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science (Wash DC) 284:1811-1816.
31. Specht CG, Tigaret CM, Rast GF, Thalhammer A, Rudhard Y, and Schoepfer R (2005) Subcellular localisation of recombinant alpha- and gamma-synuclein. Mol Cell Neurosci 28:326-334.
32. Tovar KR and Westbrook GL (1999) The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J Neurosci 19:4180-4188.
33. Turrigiano GG and Nelson SB (2004) Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci 5:97-107.
34. Weitlauf C, Honse Y, Auberson YP, Mishina M, Lovinger DM, and Winder DG (2005) Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation. J Neurosci 25:8386-8390.
35. Wenthold RJ, Petralia RS, Blahos J 2nd, and Niedzielski AS (1996) Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons. J Neurosci 16:1982-1989.
36. Wenthold RJ, Prybylowski K, Standley S, Sans N, and Petralia RS (2003) Trafficking of NMDA receptors. Annu Rev Pharmacol Toxicol 43:335-358.
37. Williams K (1993) Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44:851-859.
38. Williams K, Russell SL, Shen YM, and Molinoff PB (1993) Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro. Neuron 10:267-278.
39. Zhu JJ, Esteban JA, Hayashi Y, and Malinow R (2000) Postnatal synaptic potentiation: delivery of GluR4-containing AMPA receptors by spontaneous activity. Nat Neurosci 3:1098-1106.
40. Zhu Y, Pak D, Qin Y, McCormack SG, Kim MJ, Baumgart JP, Velamoor V, Auberson YP, Osten P, van Aelst L, et al. (2005) Rap2-JNK removes synaptic AMPA receptors during depotentiation. Neuron 46:905-916.