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Volumn 35, Issue SUPPL. 8, 2008, Pages 87-105

Biological mediators and periodontal regeneration: A review of enamel matrix proteins at the cellular and molecular levels

Author keywords

Cell biology; Enamel matrix derivative; Enamel matrix proteins; Periodontal regeneration

Indexed keywords

BIOLOGICAL FACTOR; ENAMEL MATRIX PROTEINS; ENAMEL PROTEIN;

EID: 50249129693     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2008.01264.x     Document Type: Conference Paper
Times cited : (209)

References (163)
  • 1
    • 0036885603 scopus 로고    scopus 로고
    • Antibacterial effect of an enamel matrix protein derivative on in vivo dental plaque biofilm vitality
    • Arweiler, N. B., Auschill, T. M., Donos, N. Sculean, A. (2002) Antibacterial effect of an enamel matrix protein derivative on in vivo dental plaque biofilm vitality. Clinical Oral Investigations 6, 205 209.
    • (2002) Clinical Oral Investigations , vol.6 , pp. 205-209
    • Arweiler, N.B.1    Auschill, T.M.2    Donos, N.3    Sculean, A.4
  • 2
    • 33645030546 scopus 로고    scopus 로고
    • In vitro clonogenic capacity of periodontal ligament fibroblasts cultured with Emdogain
    • Ashkenazi, M. Shaked, I. (2006) In vitro clonogenic capacity of periodontal ligament fibroblasts cultured with Emdogain. Dental Traumatology 22, 25 29.
    • (2006) Dental Traumatology , vol.22 , pp. 25-29
    • Ashkenazi, M.1    Shaked, I.2
  • 5
    • 0032185624 scopus 로고    scopus 로고
    • Dentin sialoprotein, dentin phosphoprotein, enamelysin and ameloblastin: Tooth-specific molecules that are distinctively expressed during murine dental differentiation
    • Bègue-Kirn, C., Krebsbach, P. H., Bartlett, J. D. Butler, W. T. (1998) Dentin sialoprotein, dentin phosphoprotein, enamelysin and ameloblastin: tooth-specific molecules that are distinctively expressed during murine dental differentiation. European Journal of Oral Sciences 106, 963 970.
    • (1998) European Journal of Oral Sciences , vol.106 , pp. 963-970
    • Bègue-Kirn, C.1    Krebsbach, P.H.2    Bartlett, J.D.3    Butler, W.T.4
  • 7
    • 21744444470 scopus 로고    scopus 로고
    • Are cementoblasts a subpopulation of osteoblasts or a unique phenotype?
    • Bosshardt, D. D. (2005) Are cementoblasts a subpopulation of osteoblasts or a unique phenotype? Journal of Dental Research 84, 390 406.
    • (2005) Journal of Dental Research , vol.84 , pp. 390-406
    • Bosshardt, D.D.1
  • 8
    • 0030899567 scopus 로고    scopus 로고
    • Immunodetection of enamel- and cementum-related (bone) proteins at the enamel-free area and cervical portion of the tooth in rat molars
    • Bosshardt, D. D. Nanci, A. (1997) Immunodetection of enamel- and cementum-related (bone) proteins at the enamel-free area and cervical portion of the tooth in rat molars. Journal of Bone and Mineral Research 12, 367 379.
    • (1997) Journal of Bone and Mineral Research , vol.12 , pp. 367-379
    • Bosshardt, D.D.1    Nanci, A.2
  • 9
    • 0031912555 scopus 로고    scopus 로고
    • Immunolocalization of epithelial and mesenchymal matrix constituents in association with inner enamel epithelial cells
    • Bosshardt, D. D. Nanci, A. (1998) Immunolocalization of epithelial and mesenchymal matrix constituents in association with inner enamel epithelial cells. The Journal of Histochemistry and Cytochemistry 46, 135 142.
    • (1998) The Journal of Histochemistry and Cytochemistry , vol.46 , pp. 135-142
    • Bosshardt, D.D.1    Nanci, A.2
  • 10
    • 0012879301 scopus 로고    scopus 로고
    • The pattern of expression of collagen determines the concentration and distribution of noncollagenous proeins along the forming root
    • In: (eds). pp. Rosemont: American Academy of Orthopaedic Surgeons.
    • Bosshardt, D. D. Nanci, A. (2000) The pattern of expression of collagen determines the concentration and distribution of noncollagenous proeins along the forming root. In : Goldberg, M. Boskey, A. Robinson, C. (eds). Chemistry and Biology of Mineralized Tissues. Proceedings of the Sixth International Conference, pp. 129 136. Rosemont : American Academy of Orthopaedic Surgeons.
    • (2000) Chemistry and Biology of Mineralized Tissues. Proceedings of the Sixth International Conference , pp. 129-136
    • Bosshardt, D.D.1    Nanci, A.2    Goldberg, M.3    Boskey, A.4    Robinson, C.5
  • 11
    • 1842851968 scopus 로고    scopus 로고
    • Hertwig's root sheath, enamel matrix proteins, and initiation of cementogenesis in porcine teeth
    • Bosshardt, D. D. Nanci, A. (2004) Hertwig's root sheath, enamel matrix proteins, and initiation of cementogenesis in porcine teeth. Journal of Clinical Periodontology 31, 184 192.
    • (2004) Journal of Clinical Periodontology , vol.31 , pp. 184-192
    • Bosshardt, D.D.1    Nanci, A.2
  • 12
    • 0030014724 scopus 로고    scopus 로고
    • Cementogenesis reviewed: A comparision between human premolars and rodent molars
    • Bosshardt, D. D. Schroeder, H. E. (1996) Cementogenesis reviewed: a comparision between human premolars and rodent molars. Anatomical Record 245, 267 292.
    • (1996) Anatomical Record , vol.245 , pp. 267-292
    • Bosshardt, D.D.1    Schroeder, H.E.2
  • 13
    • 0031964582 scopus 로고    scopus 로고
    • Developmental appearance and distribution of bone sialoprotein and osteopontin in human and rat cementum
    • Bosshardt, D. D., Zalzal, S., McKee, M. D. Nanci, A. (1998) Developmental appearance and distribution of bone sialoprotein and osteopontin in human and rat cementum. The Anatomical Record 250, 13 33.
    • (1998) The Anatomical Record , vol.250 , pp. 13-33
    • Bosshardt, D.D.1    Zalzal, S.2    McKee, M.D.3    Nanci, A.4
  • 15
    • 0036828071 scopus 로고    scopus 로고
    • Expression profiling of periodontal ligament cells stimulated with enamel matrix proteins in vitro: A model for tissue regeneration
    • Brett, P. M., Parkar, M., Olsen, I. Tonetti, M. (2002) Expression profiling of periodontal ligament cells stimulated with enamel matrix proteins in vitro: a model for tissue regeneration. Journal of Dental Research 81, 776 783.
    • (2002) Journal of Dental Research , vol.81 , pp. 776-783
    • Brett, P.M.1    Parkar, M.2    Olsen, I.3    Tonetti, M.4
  • 16
    • 0027545352 scopus 로고
    • Polypeptide growth factors and attachment proteins in periodontal wound healing and regeneration
    • Caffesse, R. G. Quinones, C. R. (1993) Polypeptide growth factors and attachment proteins in periodontal wound healing and regeneration. Periodontology 2000 1, 69 79.
    • (1993) Periodontology 2000 , vol.1 , pp. 69-79
    • Caffesse, R.G.1    Quinones, C.R.2
  • 18
    • 0345166875 scopus 로고    scopus 로고
    • Effect of enamel matrix derivative on human periodontal fibroblasts: Proliferation, morphology and root surface colonization. An in vitro study
    • Cattaneo, V., Rota, C., Silvestri, M., Piacentini, C., Forlino, A., Gallanti, A., Rasperini, G. Cetta, G. (2003) Effect of enamel matrix derivative on human periodontal fibroblasts: proliferation, morphology and root surface colonization. An in vitro study. Journal of Periodontal Research 38, 568 574.
    • (2003) Journal of Periodontal Research , vol.38 , pp. 568-574
    • Cattaneo, V.1    Rota, C.2    Silvestri, M.3    Piacentini, C.4    Forlino, A.5    Gallanti, A.6    Rasperini, G.7    Cetta, G.8
  • 19
    • 33748537400 scopus 로고    scopus 로고
    • Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB
    • Chong, C. H., Carnes, D. L., Moritz, A. J., Oates, T., Ryu, O. H., Simmer, J. Cochran, D. L. (2006) Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB. Journal of Periodontology 77, 1242 1252.
    • (2006) Journal of Periodontology , vol.77 , pp. 1242-1252
    • Chong, C.H.1    Carnes, D.L.2    Moritz, A.J.3    Oates, T.4    Ryu, O.H.5    Simmer, J.6    Cochran, D.L.7
  • 20
    • 0033069584 scopus 로고    scopus 로고
    • Biological mediators for periodontal regeneration
    • Cochran, D. L. Wozney, J. M. (1999) Biological mediators for periodontal regeneration. Periodontology 2000 19, 40 58.
    • (1999) Periodontology 2000 , vol.19 , pp. 40-58
    • Cochran, D.L.1    Wozney, J.M.2
  • 22
    • 35348846363 scopus 로고    scopus 로고
    • Effects of periodontal cell grafts and enamel matrix proteins on the implant-connective tissue interface: A pilot study in the minipig
    • Craig, R. G., Kamer, A. R., Kallur, S. P., Inoue, M. Tarnow, D. T. (2006) Effects of periodontal cell grafts and enamel matrix proteins on the implant-connective tissue interface: a pilot study in the minipig. Journal of Oral Implantology 32, 228 236.
    • (2006) Journal of Oral Implantology , vol.32 , pp. 228-236
    • Craig, R.G.1    Kamer, A.R.2    Kallur, S.P.3    Inoue, M.4    Tarnow, D.T.5
  • 24
    • 0037977871 scopus 로고    scopus 로고
    • Effects of enamel matrix protein application on the viability, proliferation, and attachment of human periodontal ligament fibroblasts to diseased root surfaces in vitro
    • Davenport, D. R., Mailhot, J. M., Wataha, J. C., Billman, M. A., Sharawy, M. M. Shrout, M. K. (2003) Effects of enamel matrix protein application on the viability, proliferation, and attachment of human periodontal ligament fibroblasts to diseased root surfaces in vitro. Journal of Clinical Periodontology 30, 125 131.
    • (2003) Journal of Clinical Periodontology , vol.30 , pp. 125-131
    • Davenport, D.R.1    Mailhot, J.M.2    Wataha, J.C.3    Billman, M.A.4    Sharawy, M.M.5    Shrout, M.K.6
  • 25
    • 0036020382 scopus 로고    scopus 로고
    • Effect of porcine fetal enamel matrix derivative on chondrocyte proliferation, differentiation, and local factor production is dependent on cell maturation state
    • Dean, D. D., Lohmann, C. H., Sylvia, V. L., Cochran, D. L., Liu, Y., Boyan, B. D. Schwartz, Z. (2002) Effect of porcine fetal enamel matrix derivative on chondrocyte proliferation, differentiation, and local factor production is dependent on cell maturation state. Cells Tissues Organs 171, 117 127.
    • (2002) Cells Tissues Organs , vol.171 , pp. 117-127
    • Dean, D.D.1    Lohmann, C.H.2    Sylvia, V.L.3    Cochran, D.L.4    Liu, Y.5    Boyan, B.D.6    Schwartz, Z.7
  • 28
    • 2142712500 scopus 로고    scopus 로고
    • Effect of GBR in combination with deproteinized bovine bone mineral and/or enamel matrix proteins on the healing of critical-size defects
    • Donos, N., Lang, N. P., Karoussis, I. K., Bosshardt, D., Tonetti, M. Kostopoulos, L. (2004) Effect of GBR in combination with deproteinized bovine bone mineral and/or enamel matrix proteins on the healing of critical-size defects. Clinical Oral Implants Research 15, 101 111.
    • (2004) Clinical Oral Implants Research , vol.15 , pp. 101-111
    • Donos, N.1    Lang, N.P.2    Karoussis, I.K.3    Bosshardt, D.4    Tonetti, M.5    Kostopoulos, L.6
  • 31
    • 0031612172 scopus 로고    scopus 로고
    • Sequential expression of an amelin gene in mesenchymal and epithelial cells during odontogenesis in rats
    • Fong, C. D., Cerny, R., Hammarström, L. Slaby, I. (1998) Sequential expression of an amelin gene in mesenchymal and epithelial cells during odontogenesis in rats. European Journal of Oral Sciences 106 (Suppl. 1), 324 330.
    • (1998) European Journal of Oral Sciences , vol.106 , Issue.SUPPL. 1 , pp. 324-330
    • Fong, C.D.1    Cerny, R.2    Hammarström, L.3    Slaby, I.4
  • 32
    • 0034241545 scopus 로고    scopus 로고
    • Expression of amelin and amelogenin in epithelial root sheath remnants of fully formed rat molars
    • Fong, C. D. Hammarström, L. (2000) Expression of amelin and amelogenin in epithelial root sheath remnants of fully formed rat molars. Oral Surgery Oral Medicine Oral Pathology 90, 218 223.
    • (2000) Oral Surgery Oral Medicine Oral Pathology , vol.90 , pp. 218-223
    • Fong, C.D.1    Hammarström, L.2
  • 33
    • 0242441731 scopus 로고    scopus 로고
    • Amelin: An enamel-related protein, transcribed in cells of epithelial root sheath
    • Fong, C. D., Slaby, I. Hammarström, L. (1996) Amelin: an enamel-related protein, transcribed in cells of epithelial root sheath. Journal of Bone and Mineral Research 11, 892 898.
    • (1996) Journal of Bone and Mineral Research , vol.11 , pp. 892-898
    • Fong, C.D.1    Slaby, I.2    Hammarström, L.3
  • 34
    • 0037812466 scopus 로고    scopus 로고
    • Enamel matrix derivative and titanium implants. An experimental pilot study in the rabbit
    • Franke-Stenport, V. Johansson, C. B. (2003) Enamel matrix derivative and titanium implants. An experimental pilot study in the rabbit. Journal of Clinical Periodontology 30, 359 363.
    • (2003) Journal of Clinical Periodontology , vol.30 , pp. 359-363
    • Franke-Stenport, V.1    Johansson, C.B.2
  • 36
    • 33748544282 scopus 로고    scopus 로고
    • Osteoprotegerin and receptor activator of nuclear factor-kappa B ligand modulation by enamel matrix derivative in human alveolar osteoblasts
    • Galli, C., Macaluso, G. M., Guizzardi, S., Vescovini, R., Passeri, M. Passeri, G. (2006) Osteoprotegerin and receptor activator of nuclear factor-kappa B ligand modulation by enamel matrix derivative in human alveolar osteoblasts. Journal of Periodontology 77, 1223 1228.
    • (2006) Journal of Periodontology , vol.77 , pp. 1223-1228
    • Galli, C.1    MacAluso, G.M.2    Guizzardi, S.3    Vescovini, R.4    Passeri, M.5    Passeri, G.6
  • 38
    • 1442351840 scopus 로고    scopus 로고
    • Growth and amelogenin-like factors in periodontal wound healing. a systematic review
    • Giannobile, W. V. Somerman, M. J. (2003) Growth and amelogenin-like factors in periodontal wound healing. A systematic review. Annals in Periodontology 8, 193 204.
    • (2003) Annals in Periodontology , vol.8 , pp. 193-204
    • Giannobile, W.V.1    Somerman, M.J.2
  • 39
    • 32144445748 scopus 로고    scopus 로고
    • The effect of the amelogenin fraction of enamel matrix proteins on fibroblast-mediated collagen matrix reorganization
    • Grayson, R. E., Yamakoshi, Y., Wood, E. J. Ågren, M. S. (2006) The effect of the amelogenin fraction of enamel matrix proteins on fibroblast-mediated collagen matrix reorganization. Biomaterials 27, 2926 2933.
    • (2006) Biomaterials , vol.27 , pp. 2926-2933
    • Grayson, R.E.1    Yamakoshi, Y.2    Wood, E.J.3    Ågren, M.S.4
  • 42
    • 0037713413 scopus 로고    scopus 로고
    • Effect of enamel matrix derivative on mouse fibroblasts and marrow stromal osteoblasts
    • Gurpinar, A., Onur, A., Cehreli, Z. C. Tasman, F. (2003) Effect of enamel matrix derivative on mouse fibroblasts and marrow stromal osteoblasts. Journal of Biomaterials Applications 18, 25 33.
    • (2003) Journal of Biomaterials Applications , vol.18 , pp. 25-33
    • Gurpinar, A.1    Onur, A.2    Cehreli, Z.C.3    Tasman, F.4
  • 43
    • 0035287175 scopus 로고    scopus 로고
    • Enamel matrix derivative induces matrix synthesis by cultured human periodontal fibroblast cells
    • Haase, H. R. Bartold, P. M. (2001) Enamel matrix derivative induces matrix synthesis by cultured human periodontal fibroblast cells. Journal of Periodontology 72, 341 348.
    • (2001) Journal of Periodontology , vol.72 , pp. 341-348
    • Haase, H.R.1    Bartold, P.M.2
  • 45
    • 0035345207 scopus 로고    scopus 로고
    • The effect of enamel matrix protein derivative on follicle cells in vitro
    • Hakki, S. S., Berry, J. E. Somerman, M. J. (2001) The effect of enamel matrix protein derivative on follicle cells in vitro. Journal of Periodontology 72, 679 687.
    • (2001) Journal of Periodontology , vol.72 , pp. 679-687
    • Hakki, S.S.1    Berry, J.E.2    Somerman, M.J.3
  • 46
    • 0031229903 scopus 로고    scopus 로고
    • Enamel matrix, cementum development and regeneration
    • Hammarström, L. (1997) Enamel matrix, cementum development and regeneration. Journal of Clinical Periodontology 24, 669 677.
    • (1997) Journal of Clinical Periodontology , vol.24 , pp. 669-677
    • Hammarström, L.1
  • 47
    • 0031230219 scopus 로고    scopus 로고
    • Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins
    • Hammarström, L., Heijl, L. Gestrelius, S. (1997) Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins. Journal of Clinical Periodontology 24, 669 677.
    • (1997) Journal of Clinical Periodontology , vol.24 , pp. 669-677
    • Hammarström, L.1    Heijl, L.2    Gestrelius, S.3
  • 56
    • 0034241456 scopus 로고    scopus 로고
    • In vitro wound healing responses to enamel matrix derivative
    • Hoang, A. M., Oates, T. W. Cochran, D. L. (2000) In vitro wound healing responses to enamel matrix derivative. Journal of Periodontology 71, 1270 1277.
    • (2000) Journal of Periodontology , vol.71 , pp. 1270-1277
    • Hoang, A.M.1    Oates, T.W.2    Cochran, D.L.3
  • 57
    • 3543034683 scopus 로고    scopus 로고
    • Effect of enamel matrix derivative on periodontal ligament cells in vitro is diminished by Porphyromonas gingivalis
    • Inaba, H., Kawai, S., Nakayama, K., Okahashi, N. Amano, A. (2004) Effect of enamel matrix derivative on periodontal ligament cells in vitro is diminished by Porphyromonas gingivalis. Journal of Periodontology 75, 858 865.
    • (2004) Journal of Periodontology , vol.75 , pp. 858-865
    • Inaba, H.1    Kawai, S.2    Nakayama, K.3    Okahashi, N.4    Amano, A.5
  • 64
    • 0036867430 scopus 로고    scopus 로고
    • Treatment of intrabony periodontal defects with enamel matrix derivative: A literature review
    • Kalpidis, C. D. R. Ruben, M. P. (2002) Treatment of intrabony periodontal defects with enamel matrix derivative: a literature review. Journal of Periodontology 73, 1360 1376.
    • (2002) Journal of Periodontology , vol.73 , pp. 1360-1376
    • Kalpidis, C.D.R.1    Ruben, M.P.2
  • 66
    • 0035576368 scopus 로고    scopus 로고
    • Porcine enamel matrix derivative enhances trabecular bone regeneration during wound healing of injured rat femur
    • Kawana, F., Sawae, Y., Sahara, T., Tanaka, S., Debari, K., Shimizu, M. Sasaki, T. (2001) Porcine enamel matrix derivative enhances trabecular bone regeneration during wound healing of injured rat femur. The Anatomical Record 264, 438 446.
    • (2001) The Anatomical Record , vol.264 , pp. 438-446
    • Kawana, F.1    Sawae, Y.2    Sahara, T.3    Tanaka, S.4    Debari, K.5    Shimizu, M.6    Sasaki, T.7
  • 67
    • 0035656437 scopus 로고    scopus 로고
    • ®) rapidly stimulates phosphorylation of the MAP kinase family and nuclear accumulation of smad2 in both oral epithelial and fibroblastic human cells
    • ®) rapidly stimulates phosphorylation of the MAP kinase family and nuclear accumulation of smad2 in both oral epithelial and fibroblastic human cells. Journal of Periodontal Research 36, 367 376.
    • (2001) Journal of Periodontal Research , vol.36 , pp. 367-376
    • Kawase, T.1    Okuda, K.2    Momose, M.3    Kato, Y.4    Yoshie, H.5    Burns, D.M.6
  • 69
    • 0036690146 scopus 로고    scopus 로고
    • Anti-TGF-β antibody blocks enamel matrix derivative-induced upregulation of p21WAF1/cip1 and prevents its inhibition of human oral epithelial cell proliferation
    • Kawase, T., Okuda, K., Yoshie, H. Burns, D. M. (2002) Anti-TGF-β antibody blocks enamel matrix derivative-induced upregulation of p21WAF1/cip1 and prevents its inhibition of human oral epithelial cell proliferation. Journal of Periodontal Research 37, 255 262.
    • (2002) Journal of Periodontal Research , vol.37 , pp. 255-262
    • Kawase, T.1    Okuda, K.2    Yoshie, H.3    Burns, D.M.4
  • 70
    • 4143123164 scopus 로고    scopus 로고
    • In vitro effects of enamel matrix proteins on rat bone marrow cells and gingival fibroblasts
    • Keila, S., Nemcovsky, C. E., Moses, O., Artzi, Z. Weinreb, M. (2004) In vitro effects of enamel matrix proteins on rat bone marrow cells and gingival fibroblasts. Journal of Dental Research 82, 134 138.
    • (2004) Journal of Dental Research , vol.82 , pp. 134-138
    • Keila, S.1    Nemcovsky, C.E.2    Moses, O.3    Artzi, Z.4    Weinreb, M.5
  • 72
    • 28644444913 scopus 로고    scopus 로고
    • Analysis of eosiniphilic round bodies formed after injection of enamel matrix derivative into the backs of rats
    • Kim, N. H., Tominaga, K. Tanaka, A. (2005) Analysis of eosiniphilic round bodies formed after injection of enamel matrix derivative into the backs of rats. Journal of Periodontology 76, 1934 1941.
    • (2005) Journal of Periodontology , vol.76 , pp. 1934-1941
    • Kim, N.H.1    Tominaga, K.2    Tanaka, A.3
  • 73
    • 0036668593 scopus 로고    scopus 로고
    • Factors that modulate the effects of bone morphogenetic protein-induced periodontal regeneration: A critical review
    • King, G. Cochran, D. L. (2002) Factors that modulate the effects of bone morphogenetic protein-induced periodontal regeneration: a critical review. Journal of Periodontology 73, 925 936.
    • (2002) Journal of Periodontology , vol.73 , pp. 925-936
    • King, G.1    Cochran, D.L.2
  • 74
    • 33846222329 scopus 로고    scopus 로고
    • In vitro assessment of motility and proliferation of human osteogenic cells on different isolated extracellular matrix components compared with enamel matrix derivative by continuous single-cell observation
    • Klein, M. O., Reichert, C., Koch, D., Horn, S. Al-Nawas, B. (2007) In vitro assessment of motility and proliferation of human osteogenic cells on different isolated extracellular matrix components compared with enamel matrix derivative by continuous single-cell observation. Clinical Oral Implants Research 18, 40 45.
    • (2007) Clinical Oral Implants Research , vol.18 , pp. 40-45
    • Klein, M.O.1    Reichert, C.2    Koch, D.3    Horn, S.4    Al-Nawas, B.5
  • 76
    • 33845486937 scopus 로고    scopus 로고
    • Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to an osteo-chondrogenic lineage
    • Lacerda-Pinheiro, S., Septier, D., Tompkins, K., Veis, A., Goldberg, M. Chardin, H. (2006) Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to an osteo-chondrogenic lineage. Journal of Biomedical Materials Research 79A, 1015 1022.
    • (2006) Journal of Biomedical Materials Research , vol.79 , pp. 1015-1022
    • Lacerda-Pinheiro, S.1    Septier, D.2    Tompkins, K.3    Veis, A.4    Goldberg, M.5    Chardin, H.6
  • 77
    • 36549077834 scopus 로고    scopus 로고
    • The effect of LRAP on enamel organ epithelial cell differentiation
    • Le, T. Q., Zhang, Y., Li, W. DenBesten, P. K. (2007) The effect of LRAP on enamel organ epithelial cell differentiation. Journal of Dental Research 86, 1095 1099.
    • (2007) Journal of Dental Research , vol.86 , pp. 1095-1099
    • Le, T.Q.1    Zhang, Y.2    Li, W.3    Denbesten, P.K.4
  • 78
    • 35348889630 scopus 로고    scopus 로고
    • Enamel matrix derivative promotes human periodontal ligament cell differentiation and osteoprotegerin production in vitro
    • Lossdörfer, S., Sun, M., Götz, W., Dard, M. Jäger, A. (2007) Enamel matrix derivative promotes human periodontal ligament cell differentiation and osteoprotegerin production in vitro. Journal of Dental Research 86, 980 985.
    • (2007) Journal of Dental Research , vol.86 , pp. 980-985
    • Lossdörfer, S.1    Sun, M.2    Götz, W.3    Dard, M.4    Jäger, A.5
  • 81
    • 0033071186 scopus 로고    scopus 로고
    • Development and regeneration of the periodontium: Parallels and contrasts
    • MacNeil, R. Somerman, M. J. (1999) Development and regeneration of the periodontium: parallels and contrasts. Periodontology 2000 19, 8 20.
    • (1999) Periodontology 2000 , vol.19 , pp. 8-20
    • MacNeil, R.1    Somerman, M.J.2
  • 82
    • 33748794760 scopus 로고    scopus 로고
    • Role of macromolecular assembly of enamel matrix proteins in enamel formation
    • Margolis, H. C., Beniash, E. Fowler, C. E. (2006) Role of macromolecular assembly of enamel matrix proteins in enamel formation. Journal of Dental Resarch 85, 775 793.
    • (2006) Journal of Dental Resarch , vol.85 , pp. 775-793
    • Margolis, H.C.1    Beniash, E.2    Fowler, C.E.3
  • 83
    • 0036886088 scopus 로고    scopus 로고
    • Possible involvement of extracellular signal-regulated kinases 1/2 in mitogenic response of periodontal ligament cells to enamel matrix derivative
    • Matsuda, N., Horikawa, M., Watanabe, M., Kudo, Y. Takata, T. (2002) Possible involvement of extracellular signal-regulated kinases 1/2 in mitogenic response of periodontal ligament cells to enamel matrix derivative. European Journal of Oral Sciences 110, 439 444.
    • (2002) European Journal of Oral Sciences , vol.110 , pp. 439-444
    • Matsuda, N.1    Horikawa, M.2    Watanabe, M.3    Kudo, Y.4    Takata, T.5
  • 88
    • 3242808032 scopus 로고    scopus 로고
    • Effect of heat treatment on bioactivities of enamel matrix derivatives in human periodontal ligament (HPDL) cells
    • Nagano, T., Iwata, T., Ogata, Y., Tanabe, T., Gomi, K., Fukae, M., Arai, T. Oida, S. (2004) Effect of heat treatment on bioactivities of enamel matrix derivatives in human periodontal ligament (HPDL) cells. Journal of Periodontal Research 39, 249 256.
    • (2004) Journal of Periodontal Research , vol.39 , pp. 249-256
    • Nagano, T.1    Iwata, T.2    Ogata, Y.3    Tanabe, T.4    Gomi, K.5    Fukae, M.6    Arai, T.7    Oida, S.8
  • 90
    • 0042360393 scopus 로고    scopus 로고
    • The application of bone morphogenetic proteins to dental tissue engineering
    • Nakashima, M. Reddi, A. H. (2003) The application of bone morphogenetic proteins to dental tissue engineering. Nature Biotechnology 21, 1025 1032.
    • (2003) Nature Biotechnology , vol.21 , pp. 1025-1032
    • Nakashima, M.1    Reddi, A.H.2
  • 92
    • 34547864992 scopus 로고    scopus 로고
    • Enamel matrix proteins bind to wound matrix proteins and regulate their cell-adhesive properties
    • Narani, N. N., Owen, G. R., Häkkinen, L., Putnins, E. Larjava, H. (2007) Enamel matrix proteins bind to wound matrix proteins and regulate their cell-adhesive properties. European Journal of Oral Sciences 115, 288 295.
    • (2007) European Journal of Oral Sciences , vol.115 , pp. 288-295
    • Narani, N.N.1    Owen, G.R.2    Häkkinen, L.3    Putnins, E.4    Larjava, H.5
  • 94
    • 33846295910 scopus 로고    scopus 로고
    • Enamel matrix derivative stimulates osteogenesis- and chondrogenesis-related transcription factors in C3H10T1/2 cells
    • Narukawa, M., Suzuki, N., Takayama, T., Yamashita, Y., Otsuka, K. Ito, K. (2007b) Enamel matrix derivative stimulates osteogenesis- and chondrogenesis-related transcription factors in C3H10T1/2 cells. Acta Biochimica et Biophysica Sinica 39, 1 7.
    • (2007) Acta Biochimica et Biophysica Sinica , vol.39 , pp. 1-7
    • Narukawa, M.1    Suzuki, N.2    Takayama, T.3    Yamashita, Y.4    Otsuka, K.5    Ito, K.6
  • 95
    • 0033278141 scopus 로고    scopus 로고
    • Identification of the chondrogenic-inducing activity from bovine denin (bCIA) as a low-molecular-mass amelogenin polypeptide
    • Nebgen, D. R., Inoue, H., Sabsay, B., Wei, K., Ho, C. S. Veis, A. (1999) Identification of the chondrogenic-inducing activity from bovine denin (bCIA) as a low-molecular-mass amelogenin polypeptide. Journal of Dental Research 78, 1484 1494.
    • (1999) Journal of Dental Research , vol.78 , pp. 1484-1494
    • Nebgen, D.R.1    Inoue, H.2    Sabsay, B.3    Wei, K.4    Ho, C.S.5    Veis, A.6
  • 100
    • 0037608966 scopus 로고    scopus 로고
    • Participation of endogenous IGF-1 and TGF-β1 with enamel matrix derivative-stimulated cell growth in human periodontal ligament cells
    • Okubo, K., Kobayashi, M., Takiguchi, T., Takata, T., Ohazama, A., Okamatsu, Y. Hasegawa, K. (2003) Participation of endogenous IGF-1 and TGF-β1 with enamel matrix derivative-stimulated cell growth in human periodontal ligament cells. Journal of Periodontal Research 38, 1 9.
    • (2003) Journal of Periodontal Research , vol.38 , pp. 1-9
    • Okubo, K.1    Kobayashi, M.2    Takiguchi, T.3    Takata, T.4    Ohazama, A.5    Okamatsu, Y.6    Hasegawa, K.7
  • 101
    • 0013782461 scopus 로고
    • Antimicrobial properties of a propylene glycol based topical therapeutic agent
    • Olitzky, I. (1965) Antimicrobial properties of a propylene glycol based topical therapeutic agent. Journal of Pharmacological Science 54, 787 788.
    • (1965) Journal of Pharmacological Science , vol.54 , pp. 787-788
    • Olitzky, I.1
  • 102
    • 26044482423 scopus 로고    scopus 로고
    • Enamel matrix derivative promotes osteoclast cell formation by RANKL production in mouse marrow cultures
    • Otsuka, T., Kasai, H., Yamaguchi, K. Nishihara, T. (2005) Enamel matrix derivative promotes osteoclast cell formation by RANKL production in mouse marrow cultures. Journal of Dentistry 33, 749 755.
    • (2005) Journal of Dentistry , vol.33 , pp. 749-755
    • Otsuka, T.1    Kasai, H.2    Yamaguchi, K.3    Nishihara, T.4
  • 103
    • 0017893469 scopus 로고
    • Ultrastructure of Hertwig's epithelial root sheath during early root development in premolar teeth in dogs
    • Owens, P. D. A. (1978) Ultrastructure of Hertwig's epithelial root sheath during early root development in premolar teeth in dogs. Archives of Oral Biology 23, 91 104.
    • (1978) Archives of Oral Biology , vol.23 , pp. 91-104
    • Owens, P.D.A.1
  • 104
    • 0018563094 scopus 로고
    • A light and electron microscopic study of the early stages of root surface formation in molar teeth in the rat
    • Owens, P. D. A. (1980) A light and electron microscopic study of the early stages of root surface formation in molar teeth in the rat. Archives of Oral Biology 24, 901 907.
    • (1980) Archives of Oral Biology , vol.24 , pp. 901-907
    • Owens, P.D.A.1
  • 105
    • 2442430383 scopus 로고    scopus 로고
    • The influence of enamel matrix derivative associated with insulin-like growth factor-1 on periodontal ligament fibroblasts
    • Palioto, D. B., Coletta, R. D., Graner, E., Joly, J. C. de Lima, A. F. M. (2004) The influence of enamel matrix derivative associated with insulin-like growth factor-1 on periodontal ligament fibroblasts. Journal of Periodontology 75, 498 504.
    • (2004) Journal of Periodontology , vol.75 , pp. 498-504
    • Palioto, D.B.1    Coletta, R.D.2    Graner, E.3    Joly, J.C.4    De Lima, A.F.M.5
  • 107
    • 10944243836 scopus 로고    scopus 로고
    • Gene expression profiles of periodontal ligament cells treated with enamel matrix proteins in vitro: Analysis using cDNA arrays
    • Parkar, M. H. Tonetti, M. (2004) Gene expression profiles of periodontal ligament cells treated with enamel matrix proteins in vitro: analysis using cDNA arrays. Journal of Periodontology 75, 1539 1546.
    • (2004) Journal of Periodontology , vol.75 , pp. 1539-1546
    • Parkar, M.H.1    Tonetti, M.2
  • 110
    • 0028391188 scopus 로고
    • Cellular origins and differentiation control mechanisms during periodontal development and wound healing
    • Pitaru, S., McCulloch, C. A. G. Narayanan, S. A. (1994) Cellular origins and differentiation control mechanisms during periodontal development and wound healing. Journal of Periodontal Research 29, 81 94.
    • (1994) Journal of Periodontal Research , vol.29 , pp. 81-94
    • Pitaru, S.1    McCulloch, C.A.G.2    Narayanan, S.A.3
  • 113
    • 27644453409 scopus 로고    scopus 로고
    • Enhanced proliferation, attachment and osteopontin expression by porcine periodontal cells exposed to Emdogain
    • Rincon, J. C., Xiao, Y., Young, W. G. Bartold, P. M. (2005) Enhanced proliferation, attachment and osteopontin expression by porcine periodontal cells exposed to Emdogain. Archives or Oral Biology 50, 1047 1054.
    • (2005) Archives or Oral Biology , vol.50 , pp. 1047-1054
    • Rincon, J.C.1    Xiao, Y.2    Young, W.G.3    Bartold, P.M.4
  • 114
    • 0031009749 scopus 로고    scopus 로고
    • Tissue engineering, morphogenesis, and regeneration of the periodontal tissues by bone morphogenetic proteins
    • Ripamonti, U. Reddi, A. H. (1997) Tissue engineering, morphogenesis, and regeneration of the periodontal tissues by bone morphogenetic proteins. Critical Reviews in Oral Biology and Medicine 8, 154 163.
    • (1997) Critical Reviews in Oral Biology and Medicine , vol.8 , pp. 154-163
    • Ripamonti, U.1    Reddi, A.H.2
  • 115
    • 33745326425 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and the induction of periodontal tissue regeneration
    • Ripamonti, U. Renton, L. (2006) bone morphogenetic proteins and the induction of periodontal tissue regeneration. Periodontology 2000 41, 73 87.
    • (2006) Periodontology 2000 , vol.41 , pp. 73-87
    • Ripamonti, U.1    Renton, L.2
  • 117
    • 0036999169 scopus 로고    scopus 로고
    • Effects of enamel matrix derivative on mineralized tissue formation during bone wound healing in rat parietal bone defects
    • Sawae, Y., Sahara, T., Kawana, F. Sasaki, T. (2002) Effects of enamel matrix derivative on mineralized tissue formation during bone wound healing in rat parietal bone defects. Journal of Electron Microscopy 51, 413 423.
    • (2002) Journal of Electron Microscopy , vol.51 , pp. 413-423
    • Sawae, Y.1    Sahara, T.2    Kawana, F.3    Sasaki, T.4
  • 118
  • 119
    • 0027073316 scopus 로고
    • Biological problems of regenerative cementogenesis: Synthesis and attachment of collagenous matrices on growing and established root surfaces
    • Schroeder, H. E. (1992) Biological problems of regenerative cementogenesis: synthesis and attachment of collagenous matrices on growing and established root surfaces. International Review of Cytology 42, 1 59.
    • (1992) International Review of Cytology , vol.42 , pp. 1-59
    • Schroeder, H.E.1
  • 120
    • 0034243492 scopus 로고    scopus 로고
    • Porcine fetal enamel matrix derivative stimulates proliferation but not differentiation of pre-osteoblastic 2T9 cells, inhibits proliferation and stimulates differentiation of osteoblast-like MG63 cells, and increases proliferation and differentiation of normal human osteoblast NHOst cells
    • Schwartz, Z., Carnes, D. L., Pulliam, R., Lohmann, C. H., Sylvia, V. L., Liu, Y., Dean, D. D., Cochran, D. L. Boyan, B. D. (2000) Porcine fetal enamel matrix derivative stimulates proliferation but not differentiation of pre-osteoblastic 2T9 cells, inhibits proliferation and stimulates differentiation of osteoblast-like MG63 cells, and increases proliferation and differentiation of normal human osteoblast NHOst cells. Journal of Periodontology 71, 1287 1296.
    • (2000) Journal of Periodontology , vol.71 , pp. 1287-1296
    • Schwartz, Z.1    Carnes, D.L.2    Pulliam, R.3    Lohmann, C.H.4    Sylvia, V.L.5    Liu, Y.6    Dean, D.D.7    Cochran, D.L.8    Boyan, B.D.9
  • 125
    • 26944437840 scopus 로고    scopus 로고
    • Amelogenin stimulates bone sialoprotein (BSP) expression through fibroblast growth factor 2 response element and transforming growth factor-β1 activation element in the promoter of the BSP gene
    • Shimizu, E., Saito, R., Nakayama, Y., Nakajima, Y., Kato, N., Takai, H., Kim, D. S., Arai, M., Simmer, J. Ogata, Y. (2005) Amelogenin stimulates bone sialoprotein (BSP) expression through fibroblast growth factor 2 response element and transforming growth factor-β1 activation element in the promoter of the BSP gene. Journal of Periodontal Research 76, 1482 1489.
    • (2005) Journal of Periodontal Research , vol.76 , pp. 1482-1489
    • Shimizu, E.1    Saito, R.2    Nakayama, Y.3    Nakajima, Y.4    Kato, N.5    Takai, H.6    Kim, D.S.7    Arai, M.8    Simmer, J.9    Ogata, Y.10
  • 129
    • 0016959601 scopus 로고
    • Towards a cellular and molecular understanding of periodontics: Cementogenesis revisited
    • Slavkin, H. C. (1976) Towards a cellular and molecular understanding of periodontics: cementogenesis revisited. Journal of Periodontology 47, 249 255.
    • (1976) Journal of Periodontology , vol.47 , pp. 249-255
    • Slavkin, H.C.1
  • 130
    • 0024540576 scopus 로고
    • Hertwig's epithelial root sheath differentiation and initial cementum and bone formation during long-term organ culture of mouse mandibular first molars using serumless, chemically-defined medium
    • Slavkin, H. C., Bringas, P., Bessem, C., Santos, V., Nakamura, M., Hsu, M. Y., Snead, M. L., Zeichner-David, M. Fincham, A. M. (1988) Hertwig's epithelial root sheath differentiation and initial cementum and bone formation during long-term organ culture of mouse mandibular first molars using serumless, chemically-defined medium. Journal of Periodontal Research 23, 28 40.
    • (1988) Journal of Periodontal Research , vol.23 , pp. 28-40
    • Slavkin, H.C.1    Bringas, P.2    Bessem, C.3    Santos, V.4    Nakamura, M.5    Hsu, M.Y.6    Snead, M.L.7    Zeichner-David, M.8    Fincham, A.M.9
  • 131
    • 0024540576 scopus 로고
    • Hertwig's epithelial root sheath differentiation and initial cementum and bone formation during long-term organ culture of mouse mandibular first molars using serumless, chemically-defined medium
    • Slavkin, H. C., Bringas, P., Bessem, C., Santos, V., Nakamura, M., Hsu, M. Y., Snead, M. L., Zeichner-David, M. Fincham, A. M. (1989) Hertwig's epithelial root sheath differentiation and initial cementum and bone formation during long-term organ culture of mouse mandibular first molars using serumless, chemically-defined medium. Journal of Periodontal Research 23, 28 40.
    • (1989) Journal of Periodontal Research , vol.23 , pp. 28-40
    • Slavkin, H.C.1    Bringas, P.2    Bessem, C.3    Santos, V.4    Nakamura, M.5    Hsu, M.Y.6    Snead, M.L.7    Zeichner-David, M.8    Fincham, A.M.9
  • 132
    • 34249103855 scopus 로고    scopus 로고
    • A study of enamel matrix proteins on differentiation of porcine bone marrow stromal cells into cementoblasts
    • Song, A. M., Shu, R., Xie, Y. F., Song, Z. C., Li, H. Y., Liu, X. F. Zhang, X. L. (2007) A study of enamel matrix proteins on differentiation of porcine bone marrow stromal cells into cementoblasts. Cell Proliferation 40, 381 396.
    • (2007) Cell Proliferation , vol.40 , pp. 381-396
    • Song, A.M.1    Shu, R.2    Xie, Y.F.3    Song, Z.C.4    Li, H.Y.5    Liu, X.F.6    Zhang, X.L.7
  • 135
    • 0035203629 scopus 로고    scopus 로고
    • Attachment of human periodontal ligament cells to enamel matrix-derived protein is mediated via ineraction between BSP-like molecules and integrin αvβ3
    • Suzuki, N., Ohyama, M., Maeno, M., Ito, K. Otsuka, K. (2001) Attachment of human periodontal ligament cells to enamel matrix-derived protein is mediated via ineraction between BSP-like molecules and integrin αvβ3. Journal of Periodontal Research 72, 1520 1526.
    • (2001) Journal of Periodontal Research , vol.72 , pp. 1520-1526
    • Suzuki, N.1    Ohyama, M.2    Maeno, M.3    Ito, K.4    Otsuka, K.5
  • 139
    • 17444417863 scopus 로고    scopus 로고
    • Enamel matrix derivative stimulates core binding factor α1/Runt-related transcription factor-2 expression via activation of Smad1 in C2C12 cells
    • Takayama, T., Suzuki, N., Narukawa, M., Tokunaga, T., Otsuka, K. Ito, K. (2005) Enamel matrix derivative stimulates core binding factor α1/Runt-related transcription factor-2 expression via activation of Smad1 in C2C12 cells. Journal of Periodontology 76, 244 249.
    • (2005) Journal of Periodontology , vol.76 , pp. 244-249
    • Takayama, T.1    Suzuki, N.2    Narukawa, M.3    Tokunaga, T.4    Otsuka, K.5    Ito, K.6
  • 140
    • 33746025298 scopus 로고    scopus 로고
    • Effects of enamel matrix derivative on bone-related mRNA expression in human periodontal ligament cells in vitro
    • Takayanagi, K., Osawa, G., Nakaya, H., Cochran, D. L., Kamoi, K. Oates, T. W. (2006) Effects of enamel matrix derivative on bone-related mRNA expression in human periodontal ligament cells in vitro. Journal of Periodontology 77, 891 898.
    • (2006) Journal of Periodontology , vol.77 , pp. 891-898
    • Takayanagi, K.1    Osawa, G.2    Nakaya, H.3    Cochran, D.L.4    Kamoi, K.5    Oates, T.W.6
  • 143
    • 12544250599 scopus 로고    scopus 로고
    • Two related low molecular mass polypeptide isoforms of amelogenin have distinct activities in mouse tooth germ differentiation in vitro
    • Tompkins, K., Alvares, K., George, A. Veis, A. (2005) Two related low molecular mass polypeptide isoforms of amelogenin have distinct activities in mouse tooth germ differentiation in vitro. Journal of Bone and Mineral Research 20, 341 349.
    • (2005) Journal of Bone and Mineral Research , vol.20 , pp. 341-349
    • Tompkins, K.1    Alvares, K.2    George, A.3    Veis, A.4
  • 144
    • 0035996484 scopus 로고    scopus 로고
    • Polypeptides translated from alternatively spliced transcripts of the amelogenin gene, devoid of the exon 6a,b,c region, have specific effects on tooth germ development in culture
    • Tompkins, K. Veis, A. (2002) Polypeptides translated from alternatively spliced transcripts of the amelogenin gene, devoid of the exon 6a,b,c region, have specific effects on tooth germ development in culture. Connective Tissue Research 43, 224 231.
    • (2002) Connective Tissue Research , vol.43 , pp. 224-231
    • Tompkins, K.1    Veis, A.2
  • 145
    • 0015010607 scopus 로고
    • Bone histogenesis and morphogenesis in implants of demineralized enamel and dentin
    • Urist, M. R. (1971) Bone histogenesis and morphogenesis in implants of demineralized enamel and dentin. Journal of Oral Surgery 29, 88 102.
    • (1971) Journal of Oral Surgery , vol.29 , pp. 88-102
    • Urist, M.R.1
  • 146
    • 33748367451 scopus 로고    scopus 로고
    • The effect of Emdogain on the growth and differentiation of rat bone marrow cells
    • Van den Dolder, J., Vloon, A. P. G. Jansen, J. A. (2006) The effect of Emdogain on the growth and differentiation of rat bone marrow cells. Journal of Periodontal Research 41, 471 476.
    • (2006) Journal of Periodontal Research , vol.41 , pp. 471-476
    • Van Den Dolder, J.1    Vloon, A.P.G.2    Jansen, J.A.3
  • 148
    • 0036777080 scopus 로고    scopus 로고
    • Expression of integrins by human periodontal ligament and gingival fibroblasts and their involvement in fibroblast adhesion to enamel matrix-derived proteins
    • Van der Pauw, M. T. M., Everts, V. Beertsen, W. (2002) Expression of integrins by human periodontal ligament and gingival fibroblasts and their involvement in fibroblast adhesion to enamel matrix-derived proteins. Journal of Periodontal Research 37, 317 323.
    • (2002) Journal of Periodontal Research , vol.37 , pp. 317-323
    • Van Der Pauw, M.T.M.1    Everts, V.2    Beertsen, W.3
  • 149
    • 0037280016 scopus 로고    scopus 로고
    • Amelogenin gene splice products: Potential signaling molecules
    • Veis, A. (2003) Amelogenin gene splice products: potential signaling molecules. Cellular and Molecular Life Sciences 60, 38 55.
    • (2003) Cellular and Molecular Life Sciences , vol.60 , pp. 38-55
    • Veis, A.1
  • 151
    • 17444365971 scopus 로고    scopus 로고
    • The use of enamel matrix derivative in the treatment of periodontal defects: A literature review and meta-analysis
    • Venezia, E., Goldstein, M., Boyan, B. D. Schwartz, Z. (2004) The use of enamel matrix derivative in the treatment of periodontal defects: a literature review and meta-analysis. Critical Reviews in Oral Biology and Medicine 15, 382 402.
    • (2004) Critical Reviews in Oral Biology and Medicine , vol.15 , pp. 382-402
    • Venezia, E.1    Goldstein, M.2    Boyan, B.D.3    Schwartz, Z.4
  • 155
    • 0027697096 scopus 로고
    • Ectopic bone induction by human fetal enamel proteins
    • Wang, W. (1993) Ectopic bone induction by human fetal enamel proteins. Zhonghua kouqiang yixue zazhi 28, 362 364.
    • (1993) Zhonghua Kouqiang Yixue Zazhi , vol.28 , pp. 362-364
    • Wang, W.1
  • 157
    • 0033071187 scopus 로고    scopus 로고
    • Periodontal wound healing and regeneration
    • Wikesjö, U. M. Selvig, K. A. (1999) Periodontal wound healing and regeneration. Periodontology 2000 19, 21 39.
    • (1999) Periodontology 2000 , vol.19 , pp. 21-39
    • Wikesjö, U.M.1    Selvig, K.A.2
  • 158
    • 0042760453 scopus 로고    scopus 로고
    • The effects of enamel matrix derivative (EMD) on osteoblastic cells in culture and bone regeneration in a rat skull defect
    • Yoneda, S., Itoh, D., Kuroda, S., Kondo, H., Umezawa, A., Ohya, K., Ohyama, T. Kasugai, S. (2003) The effects of enamel matrix derivative (EMD) on osteoblastic cells in culture and bone regeneration in a rat skull defect. Journal of Periodontal Research 38, 333 342.
    • (2003) Journal of Periodontal Research , vol.38 , pp. 333-342
    • Yoneda, S.1    Itoh, D.2    Kuroda, S.3    Kondo, H.4    Umezawa, A.5    Ohya, K.6    Ohyama, T.7    Kasugai, S.8
  • 159
    • 0142029670 scopus 로고    scopus 로고
    • Enamel matrix derivative exhibits angiogenic effect in vitro and in a murine model
    • Yuan, K., Chen, C. L. Lin, M. T. (2003) Enamel matrix derivative exhibits angiogenic effect in vitro and in a murine model. Journal of Clinical Periodontology 30, 732 738.
    • (2003) Journal of Clinical Periodontology , vol.30 , pp. 732-738
    • Yuan, K.1    Chen, C.L.2    Lin, M.T.3
  • 160
    • 33748581011 scopus 로고    scopus 로고
    • The induction and possible subsequent effect of human antibodies against porcine enamel matrix derivative
    • Yuan, K., Hsu, C.-W. Tsai, W.-H. (2006) The induction and possible subsequent effect of human antibodies against porcine enamel matrix derivative. Journal of Periodontology 75, 1355 1361.
    • (2006) Journal of Periodontology , vol.75 , pp. 1355-1361
    • Yuan, K.1    Hsu, C.-W.2    Tsai, W.-H.3
  • 161
  • 162
    • 35848961233 scopus 로고    scopus 로고
    • Enamel matrix derivative protects human gingival fibroblasts from TNF-induced apoptosis by inhibiting caspase activation
    • Zeldich, E., Koren, R., Dard, M., Nemcovsky, C. Weinreb, M. (2007b) Enamel matrix derivative protects human gingival fibroblasts from TNF-induced apoptosis by inhibiting caspase activation. Journal of Cellular Physiology 213, 750 758.
    • (2007) Journal of Cellular Physiology , vol.213 , pp. 750-758
    • Zeldich, E.1    Koren, R.2    Dard, M.3    Nemcovsky, C.4    Weinreb, M.5
  • 163
    • 33846552935 scopus 로고    scopus 로고
    • Enamel matrix derivative stimulates human gingival fibroblast proliferation via ERK
    • Zeldich, E., Koren, R., Nemcovsky, C. Weinreb, M. (2007a) Enamel matrix derivative stimulates human gingival fibroblast proliferation via ERK. Journal of Dental Research 86, 41 46.
    • (2007) Journal of Dental Research , vol.86 , pp. 41-46
    • Zeldich, E.1    Koren, R.2    Nemcovsky, C.3    Weinreb, M.4


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