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Volumn 28, Issue 4, 2008, Pages 413-428

TGF-β1/Smad7 signaling stimulates renal tubulointerstitial fibrosis induced by AAI

Author keywords

Aristolochic acid I; Renal tubular epithelial cells; Smad7; Transforming growth factor 1

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ALPHA SMOOTH MUSCLE ACTIN; ARISTOLOCHIC ACID; CYTOKERATIN 18; MESSENGER RNA; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; 1,3 DIOXOLANE DERIVATIVE; 4 (5 BENZO(1,3)DIOXOL 5 YL 4 PYRIDIN 2 YL 1H IMIDAZOL 2 YL)BENZAMIDE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; ACTIN; ARISTOLOCHIC ACID I; BENZAMIDE DERIVATIVE; SMAD7 PROTEIN, MOUSE; UNCLASSIFIED DRUG; VIMENTIN;

EID: 49649127999     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1080/10799890802176741     Document Type: Article
Times cited : (24)

References (37)
  • 2
    • 37849189626 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for the development of renal tubulointerstitial fibrosis
    • Rastaldi MP. Epithelial-mesenchymal transition and its implications for the development of renal tubulointerstitial fibrosis. J Nephrol 2006, 19, 407-412.
    • (2006) J Nephrol , vol.19 , pp. 407-412
    • Rastaldi, M.P.1
  • 3
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massague J. The transforming growth factor-β family. Annu Rev Cell Biol 1990, 6, 597-641.
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 597-641
    • Massague, J.1
  • 4
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J, Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am. J. Pathol 2001, 159, 1465-1475.
    • (2001) Am. J. Pathol , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 5
    • 0036088906 scopus 로고    scopus 로고
    • Renal fibrosis: Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells
    • Zeisberg M, Maeshima Y, Mosterman B, Kalluri R. Renal fibrosis: Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am J Pathol 2002, 160, 2001-2008.
    • (2002) Am J Pathol , vol.160 , pp. 2001-2008
    • Zeisberg, M.1    Maeshima, Y.2    Mosterman, B.3    Kalluri, R.4
  • 8
    • 11144324910 scopus 로고    scopus 로고
    • Both SP1 and Smad participate in mediating TGF-β1-induced HGF receptor expression in renal epithelial cells
    • Zhang X, Yang J, Li Y, Liu Y. Both SP1 and Smad participate in mediating TGF-β1-induced HGF receptor expression in renal epithelial cells. Am J Physiol Renal Physiol 2005, 288, 16-26.
    • (2005) Am J Physiol Renal Physiol , vol.288 , pp. 16-26
    • Zhang, X.1    Yang, J.2    Li, Y.3    Liu, Y.4
  • 9
    • 2442672575 scopus 로고    scopus 로고
    • Augmented cytoplasmic Smad4 induces acceleration of TGF-β1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation
    • Goto Y, Manabe N, Uchio-Yamada, K, Yamaguchi-Yamada M, Inoue N, Yamamoto Y, Ogura A, Nagano N, Miyamoto H. Augmented cytoplasmic Smad4 induces acceleration of TGF-β1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation. Cell Tissue Res 2004, 315, 209-221.
    • (2004) Cell Tissue Res , vol.315 , pp. 209-221
    • Goto, Y.1    Manabe, N.2    Uchio-Yamada, K.3    Yamaguchi-Yamada, M.4    Inoue, N.5    Yamamoto, Y.6    Ogura, A.7    Nagano, N.8    Miyamoto, H.9
  • 12
    • 0034612231 scopus 로고    scopus 로고
    • Transforming growth factor β-inducible independent binding of SMAD to the Smad7 promoter
    • Denissova NG, Pouponnot C, Long J, He D, Liu F. Transforming growth factor β-inducible independent binding of SMAD to the Smad7 promoter. PNAS 2000, 97, 6397-6402.
    • (2000) PNAS , vol.97 , pp. 6397-6402
    • Denissova, N.G.1    Pouponnot, C.2    Long, J.3    He, D.4    Liu, F.5
  • 16
    • 0031059573 scopus 로고    scopus 로고
    • Polarity of stimulation and secretion of transforming growth factor-β1 by cultured proximal tubular cells
    • Phillips AO, Steadman R, Morrisey, K, Williams JD. Polarity of stimulation and secretion of transforming growth factor-β1 by cultured proximal tubular cells. Am J Pathol 1997, 150, 1101-1111.
    • (1997) Am J Pathol , vol.150 , pp. 1101-1111
    • Phillips, A.O.1    Steadman, R.2    Morrisey, K.3    Williams, J.D.4
  • 18
    • 0034085245 scopus 로고    scopus 로고
    • Aristolochic acid Iinduced apoptosis in LLC-PK1 cells and amelioration of the apoptotic damage by calcium antagonist
    • Gao RT, Zheng FL, Liu YX, Zheng DX, Li XM, Bo YH, Liu Y. Aristolochic acid Iinduced apoptosis in LLC-PK1 cells and amelioration of the apoptotic damage by calcium antagonist. Chinese Med J 2000, 113, 418-424.
    • (2000) Chinese Med J , vol.113 , pp. 418-424
    • Gao, R.T.1    Zheng, F.L.2    Liu, Y.X.3    Zheng, D.X.4    Li, X.M.5    Bo, Y.H.6    Liu, Y.7
  • 19
    • 0038364209 scopus 로고    scopus 로고
    • Localization and phenotypical characterization of collagen-producing cells in TGF-β1-induced renal interstitial fibrosis
    • Chai Q, Krag S, Chai S. Localization and phenotypical characterization of collagen-producing cells in TGF-β1-induced renal interstitial fibrosis. Histochem Cell Biol 2003, 119, 267-280.
    • (2003) Histochem Cell Biol , vol.119 , pp. 267-280
    • Chai, Q.1    Krag, S.2    Chai, S.3
  • 20
    • 0037229290 scopus 로고    scopus 로고
    • Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells
    • Lan HY. Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells. Curr Opin Nephrol Hypertens 2003, 12, 25-29.
    • (2003) Curr Opin Nephrol Hypertens , vol.12 , pp. 25-29
    • Lan, H.Y.1
  • 21
    • 0030975645 scopus 로고    scopus 로고
    • TGF-beta in kidney fibrosis: A target for gene therapy
    • Border WA, Noble NA. TGF-beta in kidney fibrosis: A target for gene therapy. Kidney Int 1997, 51, 1388-1396.
    • (1997) Kidney Int , vol.51 , pp. 1388-1396
    • Border, W.A.1    Noble, N.A.2
  • 22
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • Heldin, CH, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997, 390, 465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    ten Dijke, P.3
  • 23
    • 33846011104 scopus 로고    scopus 로고
    • Regulation of Smad activity
    • Lan X. Regulation of Smad activity. Biochim Biophys Acta 2006, 1759, 503-513.
    • (2006) Biochim Biophys Acta , vol.1759 , pp. 503-513
    • Lan, X.1
  • 24
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • Massague J. How cells read TGF-beta signals. Nat Rev Mol Cell Biol 2000, 1, 169-178.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 169-178
    • Massague, J.1
  • 25
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-beta superfamily
    • Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science 2002, 296, 1646-1647.
    • (2002) Science , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 26
    • 0034646674 scopus 로고    scopus 로고
    • Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta
    • Gersdorff G, Susztak K, Rezvani F, Bitzer M, Liang D, Böttinger EP. Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta. J Biol Chem 2000, 275, 11320-11326.
    • (2000) J Biol Chem , vol.275 , pp. 11320-11326
    • Gersdorff, G.1    Susztak, K.2    Rezvani, F.3    Bitzer, M.4    Liang, D.5    Böttinger, E.P.6
  • 27
    • 2542609844 scopus 로고    scopus 로고
    • Flanders KC. Smad3 as a mediator of the fibrotic response. Int J Exp Pathol 2004, 85, 47-64.
    • Flanders KC. Smad3 as a mediator of the fibrotic response. Int J Exp Pathol 2004, 85, 47-64.
  • 30
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, Reith AD, Laping NJ, Hill CS.SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol 2002, 62, 65-74.
    • (2002) Mol. Pharmacol , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolas, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6    Laping, N.J.7    Hill, C.S.8
  • 34
  • 35
    • 0031964859 scopus 로고    scopus 로고
    • Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
    • Hata A, Lagna G, Massagué J, Hemmati-Brivanlou A. Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev 1998, 12, 186-197.
    • (1998) Genes Dev , vol.12 , pp. 186-197
    • Hata, A.1    Lagna, G.2    Massagué, J.3    Hemmati-Brivanlou, A.4
  • 36
    • 0036014928 scopus 로고    scopus 로고
    • Smad7 Inhibits Fibrotic Effect of TGF-β on Renal Tubular Epithelial Cells by Blocking Smad2 Activation
    • Li JH, Zhu HJ, Huang XR, Lai KN, Johnson RJ, Lan HY. Smad7 Inhibits Fibrotic Effect of TGF-β on Renal Tubular Epithelial Cells by Blocking Smad2 Activation. J Am Soc Nephrol 2002, 13, 1464-1472.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1464-1472
    • Li, J.H.1    Zhu, H.J.2    Huang, X.R.3    Lai, K.N.4    Johnson, R.J.5    Lan, H.Y.6
  • 37
    • 14844286953 scopus 로고    scopus 로고
    • Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts
    • Quan TH, He TY, Voorhees JJ, Fisher GJ. Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts. J Biol Chem 2005, 9, 8079-8085.
    • (2005) J Biol Chem , vol.9 , pp. 8079-8085
    • Quan, T.H.1    He, T.Y.2    Voorhees, J.J.3    Fisher, G.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.