The scaffold MyD88 acts to couple protein kinase Cε to toll-like receptors

Journal of Biological Chemistry

Volumn 283, Issue 27, 2008, Pages 18591-18600

  Faisal, Amir ^a   Saurin, Adrian ^a   Gregory, Bernard ^b   Foxwell, Brian ^b   Parker, Peter J ^a,c,d  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELL CULTURE; CHEMICAL REACTIONS; EMPLOYMENT; MACROPHAGES; POLYSACCHARIDES; SCAFFOLDS;

293 CELLS; BACTERIAL INFECTIONS; HUMAN MACROPHAGES; KNOCK OUTS; LIPOPOLYSACCHARIDE; MICE LACKING; MOUSE EMBRYO FIBROBLASTS; OVEREXPRESSION; PATHOGEN DETECTIONS; PROTEIN KINASES; RAW CELLS; SCAFFOLD PROTEINS; TLR SIGNALING; WILD TYPES;

PHOSPHORYLATION;

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN 14 3 3; PROTEIN KINASE C EPSILON; SERINE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; MYD88 PROTEIN, HUMAN; MYD88 PROTEIN, MOUSE; TLR2 PROTEIN, HUMAN; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE; YWHAB PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BACTERIAL INFECTION; CELL LINE; DRUG EFFECT; EMBRYO (ANATOMY); ENZYME INDUCTION; FIBROBLAST; GENETICS; GRAM NEGATIVE INFECTION; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING;

BACTERIA (MICROORGANISMS); MUS; NEGIBACTERIA; POSIBACTERIA;

14-3-3 PROTEINS; ANIMALS; CELL LINE; EMBRYO, MAMMALIAN; ENZYME INDUCTION; FIBROBLASTS; GRAM-NEGATIVE BACTERIAL INFECTIONS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C-EPSILON; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 49649123335     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710330200     Document Type: Article

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