The FOXP3+ subset of human CD4+CD8+ thymocytes is immature and subject to intrathymic selection

Immunology and Cell Biology

Volumn 86, Issue 6, 2008, Pages 523-529

  Tuovinen, Heli ^a   Pekkarinen, Pirkka T ^a   Rossi, Laura H ^a,b   Mattila, Ilkka ^b   Arstila, T Petteri ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Suppressor T cell; T cell receptor; Thymic selection; Tolerance

Indexed keywords

RAG2 PROTEIN; T LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CELL MATURATION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFANT; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE;

CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD, PRESCHOOL; DNA-BINDING PROTEINS; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOMAGNETIC SEPARATION; INFANT; INFANT, NEWBORN; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 49649097399     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2008.36     Document Type: Article

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