메뉴 건너뛰기




Volumn 12, Issue 4, 2008, Pages 1347-1359

Introducing a single-cell-derived human mesenchymal stem cell line expressing hTERT after lentiviral gene transfer

Author keywords

Gene transfer techniques; Lentivirus; Mesenchymal stem cells; Telomerase reverse transcriptase

Indexed keywords

TELOMERASE; TERT PROTEIN, HUMAN;

EID: 49549114293     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00299.x     Document Type: Article
Times cited : (176)

References (57)
  • 2
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science. 1997 276 : 71 4.
    • (1997) Science. , vol.276 , pp. 71-4
    • Prockop, D.J.1
  • 3
    • 0347627149 scopus 로고    scopus 로고
    • Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells
    • Stenderup K, Justesen J, Clausen C, Kassem M. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone. 2003 33 : 919 26.
    • (2003) Bone. , vol.33 , pp. 919-26
    • Stenderup, K.1    Justesen, J.2    Clausen, C.3    Kassem, M.4
  • 4
    • 0034047440 scopus 로고    scopus 로고
    • Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: Implications for their use in cell therapy
    • Banfi A, Muraglia A, Dozin B, Mastrogiacomo M, Cancedda R, Quarto R. Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: implications for their use in cell therapy. Exp Hematol. 2000 28 : 707 15.
    • (2000) Exp Hematol. , vol.28 , pp. 707-15
    • Banfi, A.1    Muraglia, A.2    Dozin, B.3    Mastrogiacomo, M.4    Cancedda, R.5    Quarto, R.6
  • 5
    • 0031012465 scopus 로고    scopus 로고
    • Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreserva-tion
    • Bruder SP, Jaiswal N, Haynesworth SE. Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreserva-tion. J Cell Biochem. 1997 64 : 278 94.
    • (1997) J Cell Biochem. , vol.64 , pp. 278-94
    • Bruder, S.P.1    Jaiswal, N.2    Haynesworth, S.E.3
  • 6
    • 0032748173 scopus 로고    scopus 로고
    • Propagation and senescence of human marrow stromal cells in culture: A simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate
    • DiGirolamo CM, Stokes D, Colter D, Phinney DG, Class R, Prockop DJ. Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br J Haematol. 1999 107 : 275 81.
    • (1999) Br J Haematol. , vol.107 , pp. 275-81
    • Digirolamo, C.M.1    Stokes, D.2    Colter, D.3    Phinney, D.G.4    Class, R.5    Prockop, D.J.6
  • 7
    • 4444273090 scopus 로고    scopus 로고
    • Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion
    • Baxter MA, Wynn RF, Jowitt SN, Wraith JE, Fairbairn LJ, Bellantuono I. Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion. Stem Cells. 2004 22 : 675 82.
    • (2004) Stem Cells. , vol.22 , pp. 675-82
    • Baxter, M.A.1    Wynn, R.F.2    Jowitt, S.N.3    Wraith, J.E.4    Fairbairn, L.J.5    Bellantuono, I.6
  • 9
    • 0842330317 scopus 로고    scopus 로고
    • Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondro-cytes
    • Parsch D, Fellenberg J, Brummendorf TH, Eschlbeck AM, Richter W. Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondro-cytes. J Mol Med. 2004 82 : 49 55.
    • (2004) J Mol Med. , vol.82 , pp. 49-55
    • Parsch, D.1    Fellenberg, J.2    Brummendorf, T.H.3    Eschlbeck, A.M.4    Richter, W.5
  • 12
    • 4444325936 scopus 로고    scopus 로고
    • Expression of telomerase extends longevity and enhances differentiation in human adipose tissue-derived stromal cells
    • Jun ES, Lee TH, Cho HH, Suh SY, Jung JS. Expression of telomerase extends longevity and enhances differentiation in human adipose tissue-derived stromal cells. Cell Physiol Biochem. 2004 14 : 261 8.
    • (2004) Cell Physiol Biochem. , vol.14 , pp. 261-8
    • Jun, E.S.1    Lee, T.H.2    Cho, H.H.3    Suh, S.Y.4    Jung, J.S.5
  • 13
    • 0037335705 scopus 로고    scopus 로고
    • Development and functional characterization of human bone marrow mesenchy-mal cells immortalized by enforced expression of telomerase
    • Mihara K, Imai C, Coustan-Smith E, Dome JS, Dominici M, Vanin E, Campana D. Development and functional characterization of human bone marrow mesenchy-mal cells immortalized by enforced expression of telomerase. Br J Haematol. 2003 120 : 846 9.
    • (2003) Br J Haematol. , vol.120 , pp. 846-9
    • Mihara, K.1    Imai, C.2    Coustan-Smith, E.3    Dome, J.S.4    Dominici, M.5    Vanin, E.6    Campana, D.7
  • 14
    • 0035984715 scopus 로고    scopus 로고
    • Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression
    • Shi S, Gronthos S, Chen S, Reddi A, Counter CM, Robey PG, Wang CY. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nat Biotechnol. 2002 20 : 587 91.
    • (2002) Nat Biotechnol. , vol.20 , pp. 587-91
    • Shi, S.1    Gronthos, S.2    Chen, S.3    Reddi, A.4    Counter, C.M.5    Robey, P.G.6    Wang, C.Y.7
  • 15
    • 17144384449 scopus 로고    scopus 로고
    • Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mes-enchymal stem cells
    • Burns JS, Abdallah BM, Guldberg P, Rygaard J, Schroder HD, Kassem M. Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mes-enchymal stem cells. Cancer Res. 2005 65 : 3126 35.
    • (2005) Cancer Res. , vol.65 , pp. 3126-35
    • Burns, J.S.1    Abdallah, B.M.2    Guldberg, P.3    Rygaard, J.4    Schroder, H.D.5    Kassem, M.6
  • 17
    • 0037148328 scopus 로고    scopus 로고
    • Telomerase is not an onco-gene
    • Harley CB. Telomerase is not an onco-gene. Oncogene. 2002 21 : 494 502.
    • (2002) Oncogene. , vol.21 , pp. 494-502
    • Harley, C.B.1
  • 18
    • 34447563815 scopus 로고    scopus 로고
    • Quantitative polymerase chain reaction as a reliable method to determine functional lentiviral titer after ex vivo gene transfer in human mesenchymal stem cells
    • Böker W, Rossmann O, Docheva D, Malterer G, Mutschler W, Schieker M. Quantitative polymerase chain reaction as a reliable method to determine functional lentiviral titer after ex vivo gene transfer in human mesenchymal stem cells. J Gene Med. 2007 9 : 585 95.
    • (2007) J Gene Med. , vol.9 , pp. 585-95
    • Böker, W.1    Rossmann, O.2    Docheva, D.3    Malterer, G.4    Mutschler, W.5    Schieker, M.6
  • 20
    • 2942538291 scopus 로고    scopus 로고
    • Sensitivity and reproducibility of standardized-competitive RT-PCR for transcript quantification and its comparison with real time RT-PCR
    • Pagliarulo V, George B, Beil SJ, Groshen S, Laird PW, Cai J, Willey J, Cote RJ, Datar RH. Sensitivity and reproducibility of standardized-competitive RT-PCR for transcript quantification and its comparison with real time RT-PCR. Mol Cancer. 2004 3 : 5.
    • (2004) Mol Cancer. , vol.3 , pp. 5
    • Pagliarulo, V.1    George, B.2    Beil, S.J.3    Groshen, S.4    Laird, P.W.5    Cai, J.6    Willey, J.7    Cote, R.J.8    Datar, R.H.9
  • 21
    • 27144473412 scopus 로고    scopus 로고
    • Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellu-lar carcinoma cells
    • Gan L, Yang XL, Liu Q, Xu HB. Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellu-lar carcinoma cells. J Cell Biochem. 2005 96 : 653 64.
    • (2005) J Cell Biochem. , vol.96 , pp. 653-64
    • Gan, L.1    Yang, X.L.2    Liu, Q.3    Xu, H.B.4
  • 22
    • 0034855827 scopus 로고    scopus 로고
    • Expression of multiple genes regulating cell cycle and apoptosis in differentiating hematopoietic cells is dependent on iron
    • Alcantara O, Kalidas M, Baltathakis I, Boldt DH. Expression of multiple genes regulating cell cycle and apoptosis in differentiating hematopoietic cells is dependent on iron. Exp Hematol. 2001 29 : 1060 9.
    • (2001) Exp Hematol. , vol.29 , pp. 1060-9
    • Alcantara, O.1    Kalidas, M.2    Baltathakis, I.3    Boldt, D.H.4
  • 25
    • 0034934262 scopus 로고    scopus 로고
    • Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells
    • Colter DC, Sekiya I, Prockop DJ. Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci USA. 2001 98 : 7841 5.
    • (2001) Proc Natl Acad Sci USA. , vol.98 , pp. 7841-5
    • Colter, D.C.1    Sekiya, I.2    Prockop, D.J.3
  • 26
    • 42349085049 scopus 로고    scopus 로고
    • Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy
    • Docheva D, Padula D, Popov C, Mutschler W, Clausen-Schaumann H, Schieker M. Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy. J Cell Mol Med. 2007 12 : 537 52.
    • (2007) J Cell Mol Med. , vol.12 , pp. 537-52
    • Docheva, D.1    Padula, D.2    Popov, C.3    Mutschler, W.4    Clausen-Schaumann, H.5    Schieker, M.6
  • 27
    • 85047689866 scopus 로고    scopus 로고
    • Telomeres, stem cells, senescence, and cancer
    • Sharpless NE, DePinho RA. Telomeres, stem cells, senescence, and cancer. J Clin Invest. 2004 113 : 160 8.
    • (2004) J Clin Invest. , vol.113 , pp. 160-8
    • Sharpless, N.E.1    Depinho, R.A.2
  • 28
    • 0016269155 scopus 로고
    • Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo
    • Friedenstein AJ, Chailakhyan RK, Latsinik NV, Panasyuk AF, Keiliss-Borok IV. Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation. 1974 17 : 331 40.
    • (1974) Transplantation. , vol.17 , pp. 331-40
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Latsinik, N.V.3    Panasyuk, A.F.4    Keiliss-Borok, I.V.5
  • 29
    • 0031012465 scopus 로고    scopus 로고
    • Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryop-reservation
    • Bruder SP, Jaiswal N, Haynesworth SE. Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryop-reservation. J Cell Biochem. 1997 64 : 278 94.
    • (1997) J Cell Biochem. , vol.64 , pp. 278-94
    • Bruder, S.P.1    Jaiswal, N.2    Haynesworth, S.E.3
  • 30
    • 5444247905 scopus 로고    scopus 로고
    • Does the reservoir for self-renewal stem from the ends?
    • Harrington L. Does the reservoir for self-renewal stem from the ends? Oncogene. 2004 23 : 7283 9.
    • (2004) Oncogene. , vol.23 , pp. 7283-9
    • Harrington, L.1
  • 32
    • 13644249950 scopus 로고    scopus 로고
    • Telomerase activity and telomere length of human mesenchymal stem cells. Changes during osteogenic differentiation
    • Schieker M, Gulkan H, Austrup B, Neth P, Mutschler W. Telomerase activity and telomere length of human mesenchymal stem cells. Changes during osteogenic differentiation. Orthopäe. 2004 33 : 1373 7.
    • (2004) Orthopäe. , vol.33 , pp. 1373-7
    • Schieker, M.1    Gulkan, H.2    Austrup, B.3    Neth, P.4    Mutschler, W.5
  • 33
    • 8644254420 scopus 로고    scopus 로고
    • Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth
    • Xu C, Jiang J, Sottile V, McWhir J, Lebkowski J, Carpenter MK. Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth. Stem Cells. 2004 22 : 972 80.
    • (2004) Stem Cells. , vol.22 , pp. 972-80
    • Xu, C.1    Jiang, J.2    Sottile, V.3    McWhir, J.4    Lebkowski, J.5    Carpenter, M.K.6
  • 36
    • 10444258868 scopus 로고    scopus 로고
    • Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation
    • Abdallah BM, Haack-Sorensen M, Burns JS, Elsnab B, Jakob F, Hokland P, Kassem M. Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation. Biochem Biophys Res Commun. 2005 326 : 527 38.
    • (2005) Biochem Biophys Res Commun. , vol.326 , pp. 527-38
    • Abdallah, B.M.1    Haack-Sorensen, M.2    Burns, J.S.3    Elsnab, B.4    Jakob, F.5    Hokland, P.6    Kassem, M.7
  • 39
    • 4544256099 scopus 로고    scopus 로고
    • Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells
    • Ferron S, Mira H, Franco S, Cano-Jaimez M, Bellmunt E, Ramirez C, Farinas I, Blasco MA. Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells. Development. 2004 131 : 4059 70.
    • (2004) Development. , vol.131 , pp. 4059-70
    • Ferron, S.1    Mira, H.2    Franco, S.3    Cano-Jaimez, M.4    Bellmunt, E.5    Ramirez, C.6    Farinas, I.7    Blasco, M.A.8
  • 41
    • 23844540299 scopus 로고    scopus 로고
    • Effects of telomerase and telomere length on epidermal stem cell behavior
    • Flores I, Cayuela ML, Blasco MA. Effects of telomerase and telomere length on epidermal stem cell behavior. Science. 2005 309 : 1253 6.
    • (2005) Science. , vol.309 , pp. 1253-6
    • Flores, I.1    Cayuela, M.L.2    Blasco, M.A.3
  • 43
    • 0019492389 scopus 로고
    • In vitro aging of human bone marrow derived stromal cells
    • Mets T, Verdonk G. In vitro aging of human bone marrow derived stromal cells. Mech Ageing Dev. 1981 16 : 81 9.
    • (1981) Mech Ageing Dev. , vol.16 , pp. 81-9
    • Mets, T.1    Verdonk, G.2
  • 45
    • 21044459196 scopus 로고    scopus 로고
    • Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cells
    • Hoelters J, Ciccarella M, Drechsel M, Geissler C, Gulkan H, Bocker W, Schieker M, Jochum M, Neth P. Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cells. J Gene Med. 2005 7 : 718 28.
    • (2005) J Gene Med. , vol.7 , pp. 718-28
    • Hoelters, J.1    Ciccarella, M.2    Drechsel, M.3    Geissler, C.4    Gulkan, H.5    Bocker, W.6    Schieker, M.7    Jochum, M.8    Neth, P.9
  • 51
    • 33746459740 scopus 로고    scopus 로고
    • Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of protooncogenes and tumor suppressors
    • Pardal R, Molofsky AV, He S, Morrison SJ. Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of protooncogenes and tumor suppressors. Cold Spring Harb Symp Quant Biol. 2005 70 : 177 85.
    • (2005) Cold Spring Harb Symp Quant Biol. , vol.70 , pp. 177-85
    • Pardal, R.1    Molofsky, A.V.2    He, S.3    Morrison, S.J.4
  • 53
    • 33747358598 scopus 로고    scopus 로고
    • Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway
    • Chapman EJ, Hurst CD, Pitt E, Chambers P, Aveyard JS, Knowles MA. Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway. Oncogene. 2006 25 : 5037 45.
    • (2006) Oncogene. , vol.25 , pp. 5037-45
    • Chapman, E.J.1    Hurst, C.D.2    Pitt, E.3    Chambers, P.4    Aveyard, J.S.5    Knowles, M.A.6
  • 54
    • 14844301705 scopus 로고    scopus 로고
    • Immortalization of human fetal cells: The life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway
    • Terai M, Uyama T, Sugiki T, Li XK, Umezawa A, Kiyono T. Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway. Mol Biol Cell. 2005 16 : 1491 9.
    • (2005) Mol Biol Cell. , vol.16 , pp. 1491-9
    • Terai, M.1    Uyama, T.2    Sugiki, T.3    Li, X.K.4    Umezawa, A.5    Kiyono, T.6
  • 56
    • 0034793590 scopus 로고    scopus 로고
    • The role of selection in progressive neoplastic transformation
    • Rubin H. The role of selection in progressive neoplastic transformation. Adv Cancer Res. 2001 83 : 159 207.
    • (2001) Adv Cancer Res. , vol.83 , pp. 159-207
    • Rubin, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.