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Volumn 35, Issue 7, 2004, Pages 817-824

Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status

Author keywords

cdk; cyclin D dependent kinase; GAPDH; labeling index; LI; p14ARF; p16; p53; pRb; retinoblastoma protein; reverse transcription polymerase chain reaction; RT PCR; TATA binding protein; TBP; UCs; urothelial carcinomas

Indexed keywords

GENE PRODUCT; PROTEIN P14ARF; PROTEIN P16; PROTEIN P53;

EID: 3142606708     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2004.01.019     Document Type: Article
Times cited : (25)

References (33)
  • 1
    • 0029839086 scopus 로고    scopus 로고
    • A molecular genetic model of human bladder cancer pathogenesis
    • Reznikoff C.A., Belair C.D., Yeager T.R., et al. A molecular genetic model of human bladder cancer pathogenesis. Semin Oncol. 23:1996;571-584
    • (1996) Semin Oncol , vol.23 , pp. 571-584
    • Reznikoff, C.A.1    Belair, C.D.2    Yeager, T.R.3
  • 2
    • 0028982932 scopus 로고
    • A novel p16INK4A transcript
    • Mao L., Merlo A., Bedi G., et al. A novel p16INK4A transcript. Cancer Res. 55:1995;2995-2997
    • (1995) Cancer Res , vol.55 , pp. 2995-2997
    • Mao, L.1    Merlo, A.2    Bedi, G.3
  • 3
    • 0029587551 scopus 로고
    • Alternative reading frames of theINK4 tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle D.E., Zindy F., Ashmun R.A., et al. Alternative reading frames of theINK4 tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell. 83:1995;993-1000
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3
  • 4
    • 0029060657 scopus 로고
    • Complex structure and regulation of the p16 (MTS1) locus
    • Stone S., Jiang P., Dayananth P., et al. Complex structure and regulation of the p16 (MTS1) locus. Cancer Res. 55:1995;2988-2994
    • (1995) Cancer Res , vol.55 , pp. 2988-2994
    • Stone, S.1    Jiang, P.2    Dayananth, P.3
  • 5
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M., Hannon G.J., Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature. 366:1993;704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 6
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 8
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • Zhang Y., Xiong Y., Yarbrough W.G. ARF promotes MDM2 degradation and stabilizes p53 ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell. 92:1998;725-734
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 10
    • 0030893707 scopus 로고    scopus 로고
    • Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors
    • Cordon-Cardo C., Zhang Z.F., Dalbagni G., et al. Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors. Cancer Res. 57:1997;1217-1221
    • (1997) Cancer Res , vol.57 , pp. 1217-1221
    • Cordon-Cardo, C.1    Zhang, Z.F.2    Dalbagni, G.3
  • 12
    • 0004233768 scopus 로고
    • Geneva, Switzerland: World Health Organization
    • World Health Organization. Histological Typing of Urinary Bladder Tumours. 1973;World Health Organization, Geneva, Switzerland
    • (1973) Histological Typing of Urinary Bladder Tumours
  • 13
    • 0001317018 scopus 로고    scopus 로고
    • Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas
    • Gil Diez de Medina S., Chopin D., El Marjou A., et al. Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas. Oncogene. 14:1997;323-330
    • (1997) Oncogene , vol.14 , pp. 323-330
    • Gil Diez De Medina, S.1    Chopin, D.2    El Marjou, A.3
  • 15
    • 0030826329 scopus 로고    scopus 로고
    • The prognostic value of p53 nuclear overexpression and MIB-1 as a proliferative marker in transitional cell carcinoma of the bladder
    • Popov Z., Hoznek A., Colombel M., et al. The prognostic value of p53 nuclear overexpression and MIB-1 as a proliferative marker in transitional cell carcinoma of the bladder. Cancer. 80:1997;1472-1481
    • (1997) Cancer , vol.80 , pp. 1472-1481
    • Popov, Z.1    Hoznek, A.2    Colombel, M.3
  • 16
    • 0029095473 scopus 로고
    • A microwave method that enhances detection of aberrant p53 expression in formalin-fixed, paraffin-embedded tissues
    • Resnick J.M., Cherwitz D., Knapp D., et al. A microwave method that enhances detection of aberrant p53 expression in formalin-fixed, paraffin-embedded tissues. Arch Pathol Lab Med. 119:1995;360-366
    • (1995) Arch Pathol Lab Med , vol.119 , pp. 360-366
    • Resnick, J.M.1    Cherwitz, D.2    Knapp, D.3
  • 17
    • 0033037541 scopus 로고    scopus 로고
    • The INK4A/ARF locus and its two gene products
    • Sharpless N.E., DePinho R.A. The INK4A/ARF locus and its two gene products. Curr Opin Genet Dev. 9:1999;22-30
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 22-30
    • Sharpless, N.E.1    Depinho, R.A.2
  • 18
    • 0032191393 scopus 로고    scopus 로고
    • Tumor surveillance via the ARF-p53 pathway
    • Sherr C.J. Tumor surveillance via the ARF-p53 pathway. Genes Dev. 12:1998;2984-2991
    • (1998) Genes Dev , vol.12 , pp. 2984-2991
    • Sherr, C.J.1
  • 19
    • 0028911406 scopus 로고
    • Increased p16 levels correlate with pRb alterations in human urothelial cells
    • Yeager T., Stadler W., Belair C., et al. Increased p16 levels correlate with pRb alterations in human urothelial cells. Cancer Res. 55:1995;493-497
    • (1995) Cancer Res , vol.55 , pp. 493-497
    • Yeager, T.1    Stadler, W.2    Belair, C.3
  • 20
    • 0029791633 scopus 로고    scopus 로고
    • The 9p21 region in bladder cancer cell lines: Large homozygous deletions inactivate the CDKN2, CDKN2B and MTAP genes
    • Stadler W.M., Olopade O.I. The 9p21 region in bladder cancer cell lines Large homozygous deletions inactivate the CDKN2, CDKN2B and MTAP genes. Urol Res. 24:1996;239-244
    • (1996) Urol Res , vol.24 , pp. 239-244
    • Stadler, W.M.1    Olopade, O.I.2
  • 21
    • 0033521887 scopus 로고    scopus 로고
    • Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer
    • Benedict W.F., Lerner S.P., Zhou J., et al. Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer. Oncogene. 18:1999;1197-1203
    • (1999) Oncogene , vol.18 , pp. 1197-1203
    • Benedict, W.F.1    Lerner, S.P.2    Zhou, J.3
  • 22
    • 0033031043 scopus 로고    scopus 로고
    • Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence
    • Orlow I., LaRue H., Osman I., et al. Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence. Am J Pathol. 155:1999;105-113
    • (1999) Am J Pathol , vol.155 , pp. 105-113
    • Orlow, I.1    Larue, H.2    Osman, I.3
  • 23
    • 0035730650 scopus 로고    scopus 로고
    • Frequent p16/MTS1 inactivation in early stages of urothelial carcinoma of the bladder is not associated with tumor recurrence
    • Friedrich M.G., Blind C., Milde-Langosch K., et al. Frequent p16/MTS1 inactivation in early stages of urothelial carcinoma of the bladder is not associated with tumor recurrence. Eur Urol. 40:2001;518-524
    • (2001) Eur Urol , vol.40 , pp. 518-524
    • Friedrich, M.G.1    Blind, C.2    Milde-Langosch, K.3
  • 24
    • 0033969408 scopus 로고    scopus 로고
    • Genetic alterations of the p16 gene in urothelial carcinoma in Taiwanese patients
    • Wu W.J., Kakehi Y., Chang S.F., et al. Genetic alterations of the p16 gene in urothelial carcinoma in Taiwanese patients. BJU Int. 85:2000;143-149
    • (2000) BJU Int , vol.85 , pp. 143-149
    • Wu, W.J.1    Kakehi, Y.2    Chang, S.F.3
  • 26
    • 0032403183 scopus 로고    scopus 로고
    • Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer
    • Markl I.D.C., Jones P.A. Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer. Cancer Res. 58:1998;5348-5353
    • (1998) Cancer Res , vol.58 , pp. 5348-5353
    • Markl, I.D.C.1    Jones, P.A.2
  • 28
    • 0033592584 scopus 로고    scopus 로고
    • Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer
    • Sanchez-Cespedes M., Reed A.L., Buta M., et al. Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer. Oncogene. 18:1999;5843-5849
    • (1999) Oncogene , vol.18 , pp. 5843-5849
    • Sanchez-Cespedes, M.1    Reed, A.L.2    Buta, M.3
  • 29
    • 0034660870 scopus 로고    scopus 로고
    • Different combinations of genetic/epigenetic alterations inactivate the p53 and pRb pathways in invasive human bladder cancers
    • Sarkar S., Jülicher K.P., Burger M.S., et al. Different combinations of genetic/epigenetic alterations inactivate the p53 and pRb pathways in invasive human bladder cancers. Cancer Res. 60:2000;3862-3871
    • (2000) Cancer Res , vol.60 , pp. 3862-3871
    • Sarkar, S.1    Jülicher, K.P.2    Burger, M.S.3
  • 30
    • 0032169516 scopus 로고    scopus 로고
    • The alternative product from the CDKN2A locus, p14 (ARF), participates in a regulatory feedback loop with p53 and MDM2
    • Stott F.J., Bates S., James M.C., et al. The alternative product from the CDKN2A locus, p14 (ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17:1998;5001-5014
    • (1998) EMBO J , vol.17 , pp. 5001-5014
    • Stott, F.J.1    Bates, S.2    James, M.C.3
  • 32
    • 0028865984 scopus 로고
    • INK4A in archival human solid tumors: Correlation with retinoblastoma protein expression
    • INK4A in archival human solid tumors Correlation with retinoblastoma protein expression. Cancer Res. 55:1995;6006-6011
    • (1995) Cancer Res , vol.55 , pp. 6006-6011
    • Geradts, J.1    Kratzke, R.A.2    Niehans, G.A.3
  • 33
    • 0032521376 scopus 로고    scopus 로고
    • Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53
    • Cote R.J., Dunn M.D., Chatterjee S.J., et al. Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53. Cancer Res. 58:1998;1090-1094
    • (1998) Cancer Res , vol.58 , pp. 1090-1094
    • Cote, R.J.1    Dunn, M.D.2    Chatterjee, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.