Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons

Journal of Neuroscience Research

Volumn 86, Issue 10, 2008, Pages 2339-2352

  Parihar, Mordhwaj S ^a   Kunz, Elizabeth A ^a   Brewer, Gregory J ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Excitotoxicity; Mitochondria; Neurodegenerative disease; Redox potential

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTAMIC ACID; GLUTATHIONE; IONOMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ROTENONE;

AGING; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; BRAIN HOMOGENATE; CELL SIZE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEGENERATIVE DISEASE; EMBRYO; EXCITOTOXICITY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ADENOSINE TRIPHOSPHATE; AGING; ANIMALS; CALCIUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTRON TRANSPORT COMPLEX I; FLAVIN-ADENINE DINUCLEOTIDE; GLUTAMIC ACID; GLUTATHIONE; HIPPOCAMPUS; MITOCHONDRIA; NADP; NEURONS; OXIDATION-REDUCTION; RATS; RATS, INBRED F344;

EID: 48249155387     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21679     Document Type: Article

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