Transcriptome and proteome analysis of antibody-producing mouse myeloma NS0 cells cultivated at different cell densities in perfusion culture

Biotechnology and Applied Biochemistry

Volumn 50, Issue 3, 2008, Pages 133-141

  Krampe, Britta ^a   Swiderek, Halina ^a   Al Rubeai, Mohamed ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Apoptosis; Genomics; Monoclonal antibody; NS0 cell culture; Proteomics; Transcriptome

Indexed keywords

APOPTOSIS; APOPTOTIC PROTEINS; CELL DENSITIES; CELL LINES; CELLULAR ENERGY; CELLULAR RESPONSES; COMPLEXING; CYCLIN-DEPENDENT KINASE INHIBITOR; DILUTION RATES; DOWN-REGULATION; ENERGY METABOLISM; EXPRESSION LEVELS; EXTERNAL STRESSES; FAMILY MEMBERS; GENE CODING; GENOMICS; HEAT-SHOCK PROTEINS; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HIGH CELL DENSITIES; IN-CELL; INTERFERON REGULATORY FACTOR; ISOMERASE; METABOLIC ACTIVITIES; MICRO ARRAYS; MONOCLONAL ANTIBODY; MOUSE MYELOMA; NS0 CELL CULTURE; NS0 CELLS; NUCLEAR FACTOR; OVER-EXPRESSION; PERFUSION CULTURES; PRODUCTION RATES; PROTEASOME; PROTEIN EXPRESSIONS; PROTEOME ANALYSIS; PROTEOMICS; RESPONSE PROCESS; RETINOBLASTOMA; TRANSCRIPTION-PCR; TRANSCRIPTOME; TUMOUR NECROSIS FACTOR; UP-REGULATION;

BIOCHEMISTRY; CELL DEATH; CELL GROWTH; CELLS; CHLORINE COMPOUNDS; CONTINUOUS CELL CULTURE; CYTOLOGY; GLYCOPROTEINS; LAWS AND LEGISLATION; METABOLISM; NUCLEAR FUEL REPROCESSING; PROGRAMMING THEORY; PROTEIN FOLDING; PROTEINS; TECHNOLOGY; TRANSCRIPTION; TRANSCRIPTION FACTORS; TUMORS;

CELL CULTURE;

HEAT SHOCK PROTEIN 60; I KAPPA B; IMMUNOGLOBULIN G; INTERFERON REGULATORY FACTOR 4; PROTEIN BAK; PROTEIN BAX; PROTEIN DISULFIDE ISOMERASE; PROTEIN SUBUNIT; RIBONUCLEOPROTEIN;

ANIMAL CELL; ANTIBODY PRODUCING CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL DENSITY; CELL ENERGY; CELL GROWTH; CELL METABOLISM; CELL STRESS; CELL VIABILITY; CYCLIN DEPENDENT KINASE INHIBITOR IB GENE; DILUTION; DOWN REGULATION; ENERGY METABOLISM; ENERGY YIELD; GENE EXPRESSION; GENE OVEREXPRESSION; GENOME; GROWTH RATE; HEAVY CHAIN; MOUSE; MYELOMA CELL; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MICROARRAY; PROTEOMICS; RETINOBLASTOMA I GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY GENE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL COUNT; CELL CULTURE TECHNIQUES; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; MICE; MULTIPLE MYELOMA; PROTEIN ENGINEERING; PROTEOME; TRANSCRIPTION FACTORS;

EID: 49249100804     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20070195     Document Type: Article

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