메뉴 건너뛰기




Volumn 62, Issue 3, 1998, Pages 195-207

A comparison of intensive cell culture bioreactors operating with Hybridomas modified for inhibited apoptotic response

Author keywords

Apoptosis; Bcl 2; Hybridoma; Perfusion culture; Spin filter; Ultrasonic filter

Indexed keywords

ANIMAL CELL CULTURE; CYTOLOGY; GROWTH KINETICS; PROTEINS; ULTRASONIC APPLICATIONS;

EID: 0032537765     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(98)00064-9     Document Type: Article
Times cited : (37)

References (12)
  • 1
    • 0029256479 scopus 로고
    • Death mechanisms of animal cells in conditions of intensive agitation
    • Al-Rubeai M., Singh R.P., Goldman M.H., Emery A.N. Death mechanisms of animal cells in conditions of intensive agitation. Biotechnol. Bioeng. 45:1995;463-472.
    • (1995) Biotechnol. Bioeng. , vol.45 , pp. 463-472
    • Al-Rubeai, M.1    Singh, R.P.2    Goldman, M.H.3    Emery, A.N.4
  • 2
    • 0025616789 scopus 로고
    • Perfusion systems for cell culture technology
    • In: Lubiniecki, A.S. (Ed.) Marcel Dekker, New York
    • Griffith, B., 1990. Perfusion systems for cell culture technology. In: Lubiniecki, A.S. (Ed.), Large-Scale Mammalian Cell Culture Technology. Marcel Dekker, New York, pp. 217-250.
    • (1990) Large-Scale Mammalian Cell Culture Technology , pp. 217-250
    • Griffith, B.1
  • 3
    • 0029048389 scopus 로고
    • Overexpression of bcl-2, apoptosis suppressing gene: Prolonged viable culture period of hybridoma and enhanced antibody production
    • Itoh Y., Ueda H., Suzuki E. Overexpression of bcl-2, apoptosis suppressing gene: prolonged viable culture period of hybridoma and enhanced antibody production. Biotechnol. Bioeng. 48:1995;118-122.
    • (1995) Biotechnol. Bioeng. , vol.48 , pp. 118-122
    • Itoh, Y.1    Ueda, H.2    Suzuki, E.3
  • 4
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
    • Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
    • (1972) Br. J. Cancer. , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 5
    • 0029257216 scopus 로고
    • Batch and semicontinuous aggregation and sedimentation of hybridoma cells by acoustic resonance fields
    • Phylis W.S., Trampler F., Sonderhoff S., Groeschl M., Kilburn D.G., Piret J.M. Batch and semicontinuous aggregation and sedimentation of hybridoma cells by acoustic resonance fields. Biotechnol. Prog. 11:1995;146-152.
    • (1995) Biotechnol. Prog. , vol.11 , pp. 146-152
    • Phylis, W.S.1    Trampler, F.2    Sonderhoff, S.3    Groeschl, M.4    Kilburn, D.G.5    Piret, J.M.6
  • 6
    • 0031554004 scopus 로고    scopus 로고
    • Prevention of hybridoma cell death by bcl-2 during sub optimal culture conditions
    • Simpson N.H., Milner A.E., Al-Rubeai M. Prevention of hybridoma cell death by bcl-2 during sub optimal culture conditions. Biotechnol. Bioeng. 54:1997;1-16.
    • (1997) Biotechnol. Bioeng. , vol.54 , pp. 1-16
    • Simpson, N.H.1    Milner, A.E.2    Al-Rubeai, M.3
  • 8
    • 0030571210 scopus 로고
    • Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2
    • Singh R.P., Emery A.N., Al-Rubeai M. Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2. Biotechnol. Bioeng. 52:1995;166-175.
    • (1995) Biotechnol. Bioeng. , vol.52 , pp. 166-175
    • Singh, R.P.1    Emery, A.N.2    Al-Rubeai, M.3
  • 10
    • 0000662215 scopus 로고    scopus 로고
    • Apoptosis: Exploiting novel pathways to the improvement of cell culture processes
    • Singh R.P., Al-Rubeai M., Emery A.N. Apoptosis: exploiting novel pathways to the improvement of cell culture processes. Genet. Eng. Biotechnol. 16:1996;227-251.
    • (1996) Genet. Eng. Biotechnol. , vol.16 , pp. 227-251
    • Singh, R.P.1    Al-Rubeai, M.2    Emery, A.N.3
  • 11
    • 14744298163 scopus 로고
    • Acoustic cell filter for high cell density perfusion culture of hybridoma cells
    • Trampler F., Sonderhoff S., Phylis W.S., Kilburn D.G., Piret J.M. Acoustic cell filter for high cell density perfusion culture of hybridoma cells. Bio/Technol. 12:1994;281-284.
    • (1994) Bio/Technol. , vol.12 , pp. 281-284
    • Trampler, F.1    Sonderhoff, S.2    Phylis, W.S.3    Kilburn, D.G.4    Piret, J.M.5
  • 12
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene inhuman follicular lymphoma
    • Tsujimoto Y., Cossmann J., Jaff E., Cruce C.M. Involvement of the bcl-2 gene inhuman follicular lymphoma. Science. 228:1985;1440-1443.
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossmann, J.2    Jaff, E.3    Cruce, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.