Molecular genetics of complex I-deficient Chinese hamster cell lines

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1659, Issue 2-3, 2004, Pages 160-171

  Scheffler, Immo E ^a   Yadava, Nagendra ^a   Potluri, Prasanth ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Complex I; Mitochondria; Respiration deficient mammalian cell

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; EPITOPE; PROTEIN DERIVATIVE; PROTEIN SUBUNIT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL CELL; CELL MUTANT; CHINESE HAMSTER; COMPLEX FORMATION; CONFERENCE PAPER; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENETIC CODE; GENETIC LINKAGE; HEART MITOCHONDRION; KINETICS; MITOCHONDRIAL RESPIRATION; MOLECULAR GENETICS; MOLECULAR MECHANICS; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RING OPENING; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; X CHROMOSOME LINKAGE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CRICETINAE; CRICETULUS; CROSS-LINKING REAGENTS; ELECTRON TRANSPORT COMPLEX I; MAMMALS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN SUBUNITS; PROTEIN TRANSPORT;

BOVINAE; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 9644268262     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2004.08.002     Document Type: Conference Paper

References (67)

1. H. Antonicka, I. Ogilvie, T. Taivassalo, R.P. Anitori, R.G. Haller, J. Vissing, N.G. Kennaway, and E.A. Shoubridge Identification and characterization of a common set of Complex I assembly intermediates in mitochondria from patients with complex I deficiency J. Biol. Chem. 278 2003 43081 43088
2. H.C. Au, and I.E. Scheffler A respiration-deficient Chinese hamster cell line with a defect in mitochondrial protein synthesis: rapid turnover of some mitochondrial transcripts Somat. Cell Mol. Genet. 23 1997 27 35
3. H.C. Au, B.B. Seo, A. Matsuno-Yagi, T. Yagi, and I.E. Scheffler The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria Proc. Natl. Acad. Sci. U. S. A. 96 1999 4354 4359
4. Y. Bai, and G. Attardi The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme EMBO J. 17 2001 4848 4858
5. Yidong Bai, Petr Hajek, Anne Chomyn, Elisa Chan, Byuong Boo Seo, Akemi Matsuno-Yagi, Takao Yagi, and Giuseppe Attardi Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene J. Biol. Chem. 276 2001 38808 38813
6. A. Barrientos, L. Kenyon, and C.T. Moraes Human xenomitochondrial cybrids-cellular models of mitochondrial complex I deficiency J. Biol. Chem. 273 1998 14210 14217
7. F. Baumann, W. Neupert, and J.M. Herrmann Insertion of bitopic membrane proteins into the inner membrane of mitochondria involves an export step from the matrix J. Biol. Chem. 277 2002 21405 21413
8. J. Betts, R.N. Lightowlers, and D.M. Turnbull Neuropathological aspects of mitochondrial DNA disease Neurochem. Res. 29 2004 505 511
9. K.G. Burnett, and I.E. Scheffler Integrity of mitochondria in a mammalian cell mutant defective in mitochondrial protein synthesis J. Cell Biol. 90 1981 108 115
10. J. Carroll, I.M. Fearnley, R.J. Shannon, J. Hirst, and J.E. Walker Analysis of the subunit composition of complex I from bovine heart mitochondria Mol. Cell Proteomics 2 2003 117 126
11. J. Carroll, R.J. Shannon, I.M. Fearnley, J.E. Walker, and J. Hirst Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I: identification of two new subunits J. Biol. Chem. 277 2002 50311 50317
12. R. Chen, I.M. Fearnley, S.Y. Peak_Chew, and J.E. Walker The phosphorylation of subunits of complex I from bovine heart mitochondria J. Biol. Chem. 279 2004 26036 26045
13. A. Chomyn Mitochondrial genetic control of assembly and function of complex I in mammalian cells J. Bioenerg. Biomembranes 33 2001 251 257
14. A. Chomyn, and G. Attardi MtDNA mutations in aging and apoptosis Biochem. Biophys. Res. Commun. 304 2003 519 529
15. C. Day, and I.E. Scheffler Mapping of the genes for some components of complex I of the electron transport chain on the X chromosome of mammals Somat. Cell Genet. 8 1982 691 707
16. R. Dey, A. Barrientos, and C.T. Moraes Functional constraints of nuclear-mitochondrial DNA interactions in xenomitochondrial rodent cell lines J. Biol. Chem. 275 2000 31520 31527
17. G.S. Ditta, K. Soderberg, and I.E. Scheffler Chinese hamster cell mutant with defective mitochondrial protein synthesis Nature 268 1977 64 67
18. P.L. Dutton, C.C. Moser, V.D. Sled, F. Daldal, and T. Ohnishi A reductant-induced oxidation mechanism for complex I Biochim. Biophys. Acta 1364 1998 245 257
19. T. Friedrich, and B. Bottcher The gross structure of the respiratory complex I: a Lego System Biochim. Biophys. Acta 1608 2004 (1-30) 1 9
20. T. Friedrich, and D. Scheide The respiratory complex I of bacteria, archea, and eucharya and its module common with membrane bound multisubunit hydrogenases FEBS Lett. 479 2000 1 5
21. A.C. Gemperli, P. Dimroth, and J. Steuber The respiratory complex I (NDH I) from Klebsiella pneumoniae, a sodium pump J. Biol. Chem. 277 2002 33811 33817
22. A.C. Gemperli, P. Dimroth, and J. Steuber Sodium ion cycling mediates energy coupling between complex I and ATP synthase Proc. Natl. Acad. Sci. U. S. A. 100 2003 839 844
23. X. Gong, T. Xie, L. Yu, M. Hesterberg, D. Scheide, T. Friedrich, and C.A. Yu The ubiquinone-binding site in NADH: ubiquinone oxidoreductase from Escherichia coli J. Biol. Chem. 278 2003 25731 25737
24. N.S. Green-Willms, C.A. Butler, H.M. Dunstan, and T.D. Fox Pet111p, an inner membrane-bound translational activator that limits expression of the Saccharomyces cerevisiae mitochondrial gene COX2 J. Biol. Chem. 276 2001 6392 6397
25. J.F. Hare, and R. Hodges Turnover of mitochondrial inner membrane proteins in hepatoma monolayer cultures J. Biol. Chem. 257 1982 3575 3580
26. K. Hell, W. Neupert, and R.A. Stuart Oxa1p acts as a general membrane insertion machinery for proteins encoded by mitochondrial DNA EMBO J. 20 2001 1281 1288
27. J. Hirst, J. Carroll, I.M. Fearnley, R.J. Shannon, and J.E. Walker The nuclear encoded subunits of complex I from bovine heart mitochondria Biochim. Biophys. Acta 1604 2003 (7-10) 135 150
28. R. Kuffner, A. Rohr, A. Schmiede, C. KrÅll, and U. Schulte Involvement of two novel chaperones in the assembly of mitochondrial NADH:ubiquinone oxidoreductase (complex I) J. Mol. Biol. 283 1998 409 417
29. M.C. Maj, S. Raha, T. Myint, and B.H. Robinson Regulation of NADH/CoQ oxidoreductase: do phosphorylation events affect activity? Protein J. 23 2004 25 32
30. I. Marques, M. Duarte, and A. Videira The 9.8 kDa subunit of complex I, related to bacterial Na(+)-translocating NADH dehydrogenases, is required for enzyme assembly and function in neurospora crassa J. Mol. Biol. 329 2003 283 290
31. A. Matsuno-Yagi, and T. Yagi Introduction: complex I-an L-shaped black box J. Bioenerg. Biomembranes 33 2001 155 157
32. J. Murray, B. Zhang, S.W. Taylor, D. Oglesbee, E. Fahy, M.F. Marusich, S.S. Ghosh, and R.A. Capaldi The subunit composition of the human NADH dehydrogenase obtained by a rapid one-step immunopurification J. Biol. Chem. 278 2003 13619 13622
33. F.E. Nargang, M. Preuss, W. Neupert, and J.M. Herrmann The Oxa1 protein forms a homooligomeric complex and is an essential part of the mitochondrial export translocase in Neurospora crassa J. Biol. Chem. 277 2002 12846 12853
34. T. Ohnishi Iron-sulfur clusters semiquinones in Complex I Biochim. Biophys. Acta, Bioenerg. 1364 1998 186 206
35. S. Papa The NDUFS4 nuclear gene of complex I of mitochondria and the cAMP cascade Biochim. Biophys. Acta 1555 2002 147 153
36. S. Papa, A.M. Sardanelli, S. Scacco, V. Petruzzella, Z. Technikova-Dobrova, R. Vergari, and A. Signorile The NADH: ubiquinone oxidoreductase (complex I) of the mammalian respiratory chain and the cAMP cascade J. Bioenerg. Biomembranes 34 2002 1 10
37. S. Papa, S. Scacco, A.M. Sardanelli, V. Petruzzella, R. Vergari, A. Signorile, and Z. Technikova-Dobrova Complex I and the cAMP cascade in human physiopathology Biosci. Rep. 22 2002 3 16
38. S. Papa, S. Scacco, A.M. Sardanelli, R. Vergari, F. Papa, S. Budde, Huevel L. van den, and J. Smeitink Mutation in the NDUFS4 gene of complex I abolishes cAMP-dependent activation of the complex in a child with fatal neurological syndrome FEBS Lett. 489 2001 259 262
39. P. Pasdois, C. Deveaud, P. Voisin, V. Bouchaud, M. Rigoulet, and B. Beauvoit Contribution of the phosphorylable complex I in the growth phase-dependent respiration of C6 glioma cells in vitro J. Bioenerg. Biomembranes 35 2003 439 450
40. P. Potluri, N. Yadava, and I.E. Scheffler The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) Eur. J. Biochem. 271 2004 3265 3273
41. S. Raha, A.T. Myint, L. Johnstone, and B.H. Robinson Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase Free Radic. Biol. Med. 32 2002 421 430
42. E.E. Rojo, B. Guiard, W. Neupert, and R.A. Stuart N-terminal tail export from the mitochondrial matrix. Adherence to the prokaryotic "positive inside" rule of membrane protein topology J. Biol. Chem. 274 1999 19617 19622
43. M.J. Runswick, I.M. Fearnley, J.M. Skehel, and J.E. Walker Presence of an acyl carrier protein in NADH:ubiquinone oxidoreductase from bovine heart mitochondria FEBS Lett. 286 1991 121 124
44. Scott A. Saracco, and Thomas D. Fox Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-Tail and interacts with Pnt1p and Mss2p in the inner membrane Mol. Biol. Cell 13 2002 1122 1131
45. I.E. Scheffler Mitochondria 1999 John Wiley & Sons New York
46. I.E. Scheffler Mitochondria make a come back Adv. Drug Deliv. Rev. 49 2001 3 26
47. I.E. Scheffler, and N. Yadava Molecular genetics of the mammalian NADH-ubiquinone oxidoreductase J. Bioenerg. Biomembranes 33 2001 243 250
48. R. Schneider, M. Massow, T. Lisowsky, and H. Weiss Different respiratory-defective phenotypes of Neurospora crassa and Saccharomyces cerevisiae after inactivation of the gene encoding the mitochondrial acyl carrier protein Curr. Genet. 29 1995 10 17
49. U. Schulte Biogenesis of respiratory complex I J. Bioenerg. Biomembranes 33 2001 205 212
50. J.A. Smeitink Mitochondrial disorders: clinical presentation and diagnostic dilemmas J. Inherit. Metab. Dis. 26 2003 199 207
51. K. Soderberg, J.T. Mascarello, G.A.M. Breen, and I.E. Scheffler Respiration-deficient Chinese hamster cell mutants: genetic characterization Somat. Cell Genet. 5 1979 225 240
52. R. Triepels, and A. Smeitink The human nuclear-encoded acyl carrier subunit (NDUFAB1) of the mitochondrial complex I in human pathology J. Inherit. Metab. Dis. 22 1999 163 173
53. C. Ugalde, R. Janssen, L.P. van den Heuvel, J.A. Smeitink, and L.G. Nijtmans Differences in assembly or stability of complex I and other mitochondrial OXPHOS complexes in inherited complex I deficiency Hum. Mol. Genet. 2004 (1-28)
54. C. Ugalde, R.H. Triepels, M.J. Coenen, L.P. van den Heuvel, R. Smeets, J. Uusimaa, P. Briones, J. Campistol, K. Majamaa, J.A. Smeitink, and L.G. Nijtmans Impaired complex I assembly in a Leigh syndrome patient with a novel missense mutation in the ND6 gene Ann. Neurol. 54 2003 665 669
55. E.M. Valente, P.M. Abou-Sleiman, V. Caputo, M.M. Muqit, K. Harvey, S. Gispert, Z. Ali, D. Del Turco, A.R. Bentivoglio, D.G. Healy, A. Albanese, R. Nussbaum, R. Gonzalez-Maldonado, T. Deller, S. Salvi, P. Cortelli, W.P. Gilks, D.S. Latchman, R.J. Harvey, B. Dallapiccola, G. Auburger, and N.W. Wood Hereditary early-onset Parkinson's disease caused by mutations in PINK1 Science 304 2004 1158 1160
56. L. Van den Heuvel, and J. Smeitink The oxidative phosphorylation (OXPHOS) system: nuclear genes and human genetic diseases BioEssays 23 2001 518 525
57. A. Videira, and M. Duarte On complex I and other NADH:ubiquinone reductases of Neurospora crassa mitochondria J. Bioenerg. Biomembranes 33 2001 197 203
58. A. Videira, and M. Duarte From NADH to ubiquinone in Neurospora mitochondria Biochim. Biophys. Acta 1555 2002 187 191
59. D.C. Wallace, and J.M. Eisenstadt Expression of cytoplasmically inherited genes for chloramphenicol resistance in interspecific somatic cell hybrids and cybrids Somat. Cell Genet. 5 1979 373 396
60. N. Yadava, T. Houchens, P. Potluri, and I.E. Scheffler Development and characterization of a conditional mitochondrial complex I assembly system J. Biol. Chem. 279 2004 12406 12413
61. N. Yadava, P. Potluri, E. Smith, A. Bisevac, and I.E. Scheffler Species-specific and mutant MWFE proteins. Their effect on the assembly of a functional mammalian mitochondrial complex I J. Biol. Chem. 277 2002 21221 21230
62. N. Yadava, and I.E. Scheffler Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase Mitochondrion 4 2004 1 12
63. T. Yagi, and A. Matsuno-Yagi The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: the secret unlocked Biochemistry 42 2003 2266 2274
64. M. Yamaoka, K. Isobe, H. Shitara, H. Yonekawa, S. Miyabayashi, and J.I. Hayashi Complete repopulation of mouse mitochondrial DNA-less cells with rat mitochondrial DNA restores mitochondrial translation but not mitochondrial respiratory function Genetics 155 2000 301 307
65. M. Yamaoka, T. Mikami, T. Ono, K. Nakada, and J.I. Hayashi Mice with only rat mtDNA are required as models of mitochondrial diseases Biochem. Biophys. Res. Commun. 282 2001 (4-6) 707 711
66. T. Yano, S. Magnitsky, and T. Ohnishi Characterization of the complex I-associated ubisemiquinone species: toward the understanding of their functional roles in the electron/proton transfer reaction Biochim. Biophys. Acta 1459 2000 299 304
67. T. Yano, and T. Yagi H+-translocating NADH-quinone oxidoreductase (NDH-1) of Paracoccus denitrificans J. Biol. Chem. 274 1999 28606 28611