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Volumn 10, Issue 1, 2008, Pages 24-39

Chronic exposure to dietary sterol glucosides is neurotoxic to motor neurons and induces an ALS-PDC phenotype

Author keywords

ALS; ALS PDC; BSSG; Environmental toxicity; Etiology; Guam; Parkinsonism

Indexed keywords

GLUCOSIDE; PHYTOSTEROL; SITOSTEROL;

EID: 49249093264     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12017-007-8020-z     Document Type: Article
Times cited : (64)

References (81)
  • 1
    • 0033779559 scopus 로고    scopus 로고
    • Astrocyte glutamate transport: Review of properties, regulation, and physiological functions
    • C. M. Anderson R. A. Swanson 2000 Astrocyte glutamate transport: Review of properties, regulation, and physiological functions Glia 32 1 14
    • (2000) Glia , vol.32 , pp. 1-14
    • Anderson, C.M.1    Swanson, R.A.2
  • 2
    • 0031753142 scopus 로고    scopus 로고
    • A loss of functional spinal alpha motor neurons in amyotrophic lateral sclerosis
    • K. Arasaki M. Tamaki 1998 A loss of functional spinal alpha motor neurons in amyotrophic lateral sclerosis Neurology 51 603 605
    • (1998) Neurology , vol.51 , pp. 603-605
    • Arasaki, K.1    Tamaki, M.2
  • 4
    • 0344609220 scopus 로고    scopus 로고
    • Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis
    • P. Barneoud O. Curet 1999 Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis Experimental Neurology 155 243 251
    • (1999) Experimental Neurology , vol.155 , pp. 243-251
    • Barneoud, P.1    Curet, O.2
  • 6
    • 33751096969 scopus 로고    scopus 로고
    • Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain
    • I. Bjorkhem 2006 Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain Journal of Internal Medicine 260 493 508
    • (2006) Journal of Internal Medicine , vol.260 , pp. 493-508
    • Bjorkhem, I.1
  • 8
    • 34249696967 scopus 로고    scopus 로고
    • Beta-methylamino-alanine (BMAA) injures hippocampal neurons in vivo
    • E. J Buenz C. L. Howe 2007 Beta-methylamino-alanine (BMAA) injures hippocampal neurons in vivo Neurotoxicology 28 702 704
    • (2007) Neurotoxicology , vol.28 , pp. 702-704
    • Buenz, E.J.1    Howe, C.L.2
  • 9
    • 10744227580 scopus 로고    scopus 로고
    • In situ hybridization for detection of nocardial 16S rRNA: Reactivity within intracellular inclusions in experimentally infected cynomolgus monkeys-and in Lewy body-containing human brain specimens
    • G. Chapman B. L. Beaman D. A. Loeffler D. M. Camp E. F. Domino D. W. Dickson W. G. Ellis I. Chen S. E. Bachus P. A. LeWitt 2003 In situ hybridization for detection of nocardial 16S rRNA: Reactivity within intracellular inclusions in experimentally infected cynomolgus monkeys-and in Lewy body-containing human brain specimens Experimental Neurology 184 715 725
    • (2003) Experimental Neurology , vol.184 , pp. 715-725
    • Chapman, G.1    Beaman, B.L.2    Loeffler, D.A.3    Camp, D.M.4    Domino, E.F.5    Dickson, D.W.6    Ellis, W.G.7    Chen, I.8    Bachus, S.E.9    Lewitt, P.A.10
  • 10
    • 33746309821 scopus 로고    scopus 로고
    • Lack of behavioral and neuropathological effects of dietary b-methylaminoalanine (BMAA) in mice
    • R. Cruz-Aguado D. Winkler C. A. Shaw 2006 Lack of behavioral and neuropathological effects of dietary b-methylaminoalanine (BMAA) in mice Pharmacology, Biochemistry, and Behavior 84 294 299
    • (2006) Pharmacology, Biochemistry, and Behavior , vol.84 , pp. 294-299
    • Cruz-Aguado, R.1    Winkler, D.2    Shaw, C.A.3
  • 11
    • 0031712390 scopus 로고    scopus 로고
    • Evaluation of neuronal loss, astrocytosis and abnormalities of cytoskeletal components of large motor neurons in the human anterior horn in aging
    • F. F. Cruz-Sanchez A. Moral E. Tolosa J. de Belleroche M. L. Rossi 1998 Evaluation of neuronal loss, astrocytosis and abnormalities of cytoskeletal components of large motor neurons in the human anterior horn in aging Journal of Neural Transmission 105 689 701
    • (1998) Journal of Neural Transmission , vol.105 , pp. 689-701
    • Cruz-Sanchez, F.F.1    Moral, A.2    Tolosa, E.3    De Belleroche, J.4    Rossi, M.L.5
  • 12
    • 0034254336 scopus 로고    scopus 로고
    • Link between Helicobacter pylori infection and idiopathic parkinsonism
    • S. M. Dobbs R. J. Dobbs C. Weller A. Charlett 2000 Link between Helicobacter pylori infection and idiopathic parkinsonism Medical Hypotheses 55 93 98
    • (2000) Medical Hypotheses , vol.55 , pp. 93-98
    • Dobbs, S.M.1    Dobbs, R.J.2    Weller, C.3    Charlett, A.4
  • 14
  • 18
    • 0030237082 scopus 로고    scopus 로고
    • Spatial and nonspatial learning in mice: Effects of S100 beta overexpression and age
    • R. Gerlai J. Roder 1996 Spatial and nonspatial learning in mice: Effects of S100 beta overexpression and age Neurobiology of Learning and Memory 66 143 154
    • (1996) Neurobiology of Learning and Memory , vol.66 , pp. 143-154
    • Gerlai, R.1    Roder, J.2
  • 19
    • 0000862813 scopus 로고
    • Steroids
    • New series. Secondary plant products
    • Grunwald, C. (1980) Steroids. In Encyclopedia of plant physiology. New series. Secondary plant products, Vol. 8, p. 221.
    • (1980) Encyclopedia of Plant Physiology , vol.8 , pp. 221
    • Grunwald, C.1
  • 20
    • 0032125587 scopus 로고    scopus 로고
    • Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
    • E. D. Hall J. A. Oostveen M. E. Gurney 1998 Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS Glia 23 249 256
    • (1998) Glia , vol.23 , pp. 249-256
    • Hall, E.D.1    Oostveen, J.A.2    Gurney, M.E.3
  • 22
    • 0029148371 scopus 로고
    • Unique cholesteryl glucosides in Helicobacter pylori: Composition and structural analysis
    • Y. Hirai M. Haque T. Yoshida K. Yokota T. Yasuda K. Oguma 1995 Unique cholesteryl glucosides in Helicobacter pylori: Composition and structural analysis Journal of Bacteriology 177 5327 5333
    • (1995) Journal of Bacteriology , vol.177 , pp. 5327-5333
    • Hirai, Y.1    Haque, M.2    Yoshida, T.3    Yokota, K.4    Yasuda, T.5    Oguma, K.6
  • 23
    • 27844492824 scopus 로고    scopus 로고
    • Species and strain differences in the expression of a novel glutamate-modulating cannabinoid receptor in the rodent hippocampus
    • A. F. Hoffman A. M. Macgill D. Smith M. Oz C. R. Lupica 2005 Species and strain differences in the expression of a novel glutamate-modulating cannabinoid receptor in the rodent hippocampus The European Journal of Neuroscience 22 2387 2391
    • (2005) The European Journal of Neuroscience , vol.22 , pp. 2387-2391
    • Hoffman, A.F.1    MacGill, A.M.2    Smith, D.3    Oz, M.4    Lupica, C.R.5
  • 24
    • 0028801536 scopus 로고
    • Cholesterol for synthesis of myelin is made locally, not imported into brain
    • H. Jurevics P. Morell 1995 Cholesterol for synthesis of myelin is made locally, not imported into brain Journal of Neurochemistry 64 895 901
    • (1995) Journal of Neurochemistry , vol.64 , pp. 895-901
    • Jurevics, H.1    Morell, P.2
  • 25
  • 27
    • 0026605961 scopus 로고
    • Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue
    • T. Kawamata H. Akiyama T. Yamada P. L. McGeer 1992 Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue American Journal of Pathology 140 691 707
    • (1992) American Journal of Pathology , vol.140 , pp. 691-707
    • Kawamata, T.1    Akiyama, H.2    Yamada, T.3    McGeer, P.L.4
  • 28
  • 32
    • 0015402167 scopus 로고
    • An appraisal of the neurotoxicity of cycad and the etiology of amyotrophic lateral sclerosis on Guam
    • L. T. Kurland 1972 An appraisal of the neurotoxicity of cycad and the etiology of amyotrophic lateral sclerosis on Guam Federation Proceedings 31 1540 1542
    • (1972) Federation Proceedings , vol.31 , pp. 1540-1542
    • Kurland, L.T.1
  • 34
    • 0023946960 scopus 로고
    • Amyotrophic lateral sclerosis and Parkinson's disease complex on Guam linked to an environmental neurotoxin
    • L. T. Kurland 1988 Amyotrophic lateral sclerosis and Parkinson's disease complex on Guam linked to an environmental neurotoxin Trends in Neuroscience 11 51 54
    • (1988) Trends in Neuroscience , vol.11 , pp. 51-54
    • Kurland, L.T.1
  • 35
    • 49249124407 scopus 로고    scopus 로고
    • Characterization of gait analysis, memory, and neuromuscular junction integrity in a mouse model of ALS-PDC
    • San Diego, CA: Society for Neuroscience.
    • Lee, G., Cruz-Aguado, R., Banjo, O. C., & Shaw, C. A. (2007). Characterization of gait analysis, memory, and neuromuscular junction integrity in a mouse model of ALS-PDC. In Neuroscience meeting planner. San Diego, CA: Society for Neuroscience.
    • (2007) Neuroscience Meeting Planner
    • Lee, G.1    Cruz-Aguado, R.2    Banjo, O.C.3    Shaw, C.A.4
  • 38
    • 33846869461 scopus 로고    scopus 로고
    • Novel environmental toxins: Steryl glycosides as a potential etiological factor for age-related neurodegenerative diseases
    • P. T. Ly S. Singh C. A. Shaw 2007 Novel environmental toxins: Steryl glycosides as a potential etiological factor for age-related neurodegenerative diseases Journal of Neuroscience Research 85 231 237
    • (2007) Journal of Neuroscience Research , vol.85 , pp. 231-237
    • Ly, P.T.1    Singh, S.2    Shaw, C.A.3
  • 39
    • 0028877220 scopus 로고
    • Effects of orally administered liposomes with soybean-derived sterols and their glucosides on rat body weight
    • Y. Maitani M. Hazama H. Tojo X. R. Qi T. Nagai 1995 Effects of orally administered liposomes with soybean-derived sterols and their glucosides on rat body weight Biological and Pharmaceutical Bulletin 18 1551 1555
    • (1995) Biological and Pharmaceutical Bulletin , vol.18 , pp. 1551-1555
    • Maitani, Y.1    Hazama, M.2    Tojo, H.3    Qi, X.R.4    Nagai, T.5
  • 40
    • 24944554895 scopus 로고    scopus 로고
    • Cycad toxins and neurological diseases in Guam: Defining theoretical experimental standards for correlating human disease with environmental toxins
    • T. Marler V. Lee C. A. Shaw 2005 Cycad toxins and neurological diseases in Guam: Defining theoretical experimental standards for correlating human disease with environmental toxins Horticultural Science 40 1607 1611
    • (2005) Horticultural Science , vol.40 , pp. 1607-1611
    • Marler, T.1    Lee, V.2    Shaw, C.A.3
  • 41
    • 33748454298 scopus 로고    scopus 로고
    • Steryl glucoside concentration declines with Cycas micronesica seed age
    • T. E. Marler V. Lee J. Chung C. A. Shaw 2006 Steryl glucoside concentration declines with Cycas micronesica seed age Functional Plant Biology 33 857 862
    • (2006) Functional Plant Biology , vol.33 , pp. 857-862
    • Marler, T.E.1    Lee, V.2    Chung, J.3    Shaw, C.A.4
  • 44
    • 0031026232 scopus 로고    scopus 로고
    • Heat stress induces a glycosylation of membrane sterol in myxoamoebae of a true slime mold, Physarum polycephalum
    • K. Murakami-Murofushi K. Nishikawa E. Hirakawa H. Murofushi 1997 Heat stress induces a glycosylation of membrane sterol in myxoamoebae of a true slime mold, Physarum polycephalum Journal of Biological Chemistry 272 486 489
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 486-489
    • Murakami-Murofushi, K.1    Nishikawa, K.2    Hirakawa, E.3    Murofushi, H.4
  • 46
    • 0025753813 scopus 로고
    • Influence of psychogenetics in opiate tolerance and abstinence in mice
    • M. Navarro J. C. Leza I. Lizasoain P. Lorenzo 1991 Influence of psychogenetics in opiate tolerance and abstinence in mice General Pharmacology 22 713 716
    • (1991) General Pharmacology , vol.22 , pp. 713-716
    • Navarro, M.1    Leza, J.C.2    Lizasoain, I.3    Lorenzo, P.4
  • 47
    • 34248570330 scopus 로고    scopus 로고
    • The digitalis-like steroid hormones: New mechanisms of action and biological significance
    • M. Nesher U. Shpolansky H. Rosen D. Lichtstein 2007 The digitalis-like steroid hormones: New mechanisms of action and biological significance Life Science 80 2093 2107
    • (2007) Life Science , vol.80 , pp. 2093-2107
    • Nesher, M.1    Shpolansky, U.2    Rosen, H.3    Lichtstein, D.4
  • 48
    • 0036746151 scopus 로고    scopus 로고
    • High frequency of systemic mycoplasmal infections in Gulf War veterans and civilians with amyotrophic lateral sclerosis (ALS)
    • G. L. Nicolson M. Y. Nasralla J. Haier J. Pomfret 2002 High frequency of systemic mycoplasmal infections in Gulf War veterans and civilians with amyotrophic lateral sclerosis (ALS) Journal of Clinical Neuroscience 9 525 529
    • (2002) Journal of Clinical Neuroscience , vol.9 , pp. 525-529
    • Nicolson, G.L.1    Nasralla, M.Y.2    Haier, J.3    Pomfret, J.4
  • 50
    • 0030724509 scopus 로고    scopus 로고
    • The importance of sitosterol and sitosterolin in human and animal nutrition
    • K. H. Pegel 1997 The importance of sitosterol and sitosterolin in human and animal nutrition South African Journal of Science 93 263 268
    • (1997) South African Journal of Science , vol.93 , pp. 263-268
    • Pegel, K.H.1
  • 51
    • 0024834716 scopus 로고
    • Beta-N-methylamino-l-alanine. Chronic oral administration is not neurotoxic to mice
    • T. L. Perry C. Bergeron A. J. Biro S. Hansen 1989 Beta-N-methylamino-l- alanine. Chronic oral administration is not neurotoxic to mice Journal of Neurological Science 94 173 180
    • (1989) Journal of Neurological Science , vol.94 , pp. 173-180
    • Perry, T.L.1    Bergeron, C.2    Biro, A.J.3    Hansen, S.4
  • 53
  • 54
    • 0346156083 scopus 로고    scopus 로고
    • Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis
    • S. D. Rao J. H. Weiss 2004 Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis Trends in Neuroscience 27 17 23
    • (2004) Trends in Neuroscience , vol.27 , pp. 17-23
    • Rao, S.D.1    Weiss, J.H.2
  • 55
    • 0036562876 scopus 로고    scopus 로고
    • Distribution of two splice variants of the glutamate transporter GLT-1 in rat brain and pituitary
    • P. Reye R. Sullivan H. Scott D. V. Pow 2002 Distribution of two splice variants of the glutamate transporter GLT-1 in rat brain and pituitary Glia 38 246 255
    • (2002) Glia , vol.38 , pp. 246-255
    • Reye, P.1    Sullivan, R.2    Scott, H.3    Pow, D.V.4
  • 56
    • 0024344673 scopus 로고
    • Beta-N-oxalylamino-L-alanine action on glutamate receptors
    • S. M. Ross D. N. Roy P. S. Spencer 1989 Beta-N-oxalylamino-L-alanine action on glutamate receptors Journal of Neurochemistry 53 710 715
    • (1989) Journal of Neurochemistry , vol.53 , pp. 710-715
    • Ross, S.M.1    Roy, D.N.2    Spencer, P.S.3
  • 57
    • 0034073227 scopus 로고    scopus 로고
    • The safety evaluation of phytosterol esters. Part 6. the comparative absorption and tissue distribution of phytosterols in the rat
    • D. J. Sanders H. J. Minter D. Howes P. A. Hepburn 2000 The safety evaluation of phytosterol esters. Part 6. The comparative absorption and tissue distribution of phytosterols in the rat Food and Chemical Toxicology 38 485 491
    • (2000) Food and Chemical Toxicology , vol.38 , pp. 485-491
    • Sanders, D.J.1    Minter, H.J.2    Howes, D.3    Hepburn, P.A.4
  • 58
    • 25444522220 scopus 로고    scopus 로고
    • Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis
    • S. A. Sargsyan P. N. Monk P. J. Shaw 2005 Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis Glia 51 241 253
    • (2005) Glia , vol.51 , pp. 241-253
    • Sargsyan, S.A.1    Monk, P.N.2    Shaw, P.J.3
  • 59
    • 0032941952 scopus 로고    scopus 로고
    • Immunoreactivity of beta-amyloid precursor protein in amyotrophic lateral sclerosis
    • S. Sasaki M. Iwata 1999 Immunoreactivity of beta-amyloid precursor protein in amyotrophic lateral sclerosis Acta Neuropathology (Berl) 97 463 468
    • (1999) Acta Neuropathology (Berl) , vol.97 , pp. 463-468
    • Sasaki, S.1    Iwata, M.2
  • 61
    • 0030761292 scopus 로고    scopus 로고
    • Formulation of liposomes with a soybean-derived sterylglucoside mixture and cholesterol for liver targeting
    • K. Shimizu Y. Maitani K. Takayama T. Nagai 1997 Formulation of liposomes with a soybean-derived sterylglucoside mixture and cholesterol for liver targeting Biological and Pharmaceutical Bulletin 20 881 886
    • (1997) Biological and Pharmaceutical Bulletin , vol.20 , pp. 881-886
    • Shimizu, K.1    Maitani, Y.2    Takayama, K.3    Nagai, T.4
  • 63
    • 34347375050 scopus 로고    scopus 로고
    • Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by BMP-7 and advanced glycation end-product inhibitors
    • Sugimoto, H., Grahovac, G., Zeisberg, M., & Kalluri, R. (2007). Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by BMP-7 and advanced glycation end-product inhibitors. Diabetes, 56(7), 1825-1833.
    • (2007) Diabetes , vol.56 , Issue.7 , pp. 1825-1833
    • Sugimoto, H.1    Grahovac, G.2    Zeisberg, M.3    Kalluri, R.4
  • 64
    • 0026295040 scopus 로고
    • In vivo application of lipoproteins as drug carriers: Pharmacological evaluation of sterylglucoside-lipoprotein complexes
    • M. Sugiyama J. Seki 1991 In vivo application of lipoproteins as drug carriers: Pharmacological evaluation of sterylglucoside-lipoprotein complexes Targeted Diagnosis and Therapy 5 315 350
    • (1991) Targeted Diagnosis and Therapy , vol.5 , pp. 315-350
    • Sugiyama, M.1    Seki, J.2
  • 65
    • 0017698204 scopus 로고
    • The numbers of limb motor neurons in the human lumbosacral cord throughout life
    • B. E. Tomlinson D. Irving 1977 The numbers of limb motor neurons in the human lumbosacral cord throughout life Journal of Neurological Sciences 34 213 219
    • (1977) Journal of Neurological Sciences , vol.34 , pp. 213-219
    • Tomlinson, B.E.1    Irving, D.2
  • 68
    • 34247893743 scopus 로고    scopus 로고
    • Cerebral angiogenic factors, angiogenesis, and physiological response to chronic hypoxia differ among four commonly used mouse strains
    • N. L. Ward E. Moore K. Noon N. Spassil E. Keenan T. L. Ivanco J. C. LaManna 2007 Cerebral angiogenic factors, angiogenesis, and physiological response to chronic hypoxia differ among four commonly used mouse strains Journal of Applied Physiology 102 1927 1935
    • (2007) Journal of Applied Physiology , vol.102 , pp. 1927-1935
    • Ward, N.L.1    Moore, E.2    Noon, K.3    Spassil, N.4    Keenan, E.5    Ivanco, T.L.6    Lamanna, J.C.7
  • 69
    • 0031282642 scopus 로고    scopus 로고
    • UDP-glucose: Sterol glucosyltransferase: Cloning and functional expression in Escherichia coli
    • D. C. Warnecke M. Baltrusch F. Buck F. P. Wolter E. Heinz 1997 UDP-glucose: Sterol glucosyltransferase: Cloning and functional expression in Escherichia coli Plant Molecular Biology 35 597 603
    • (1997) Plant Molecular Biology , vol.35 , pp. 597-603
    • Warnecke, D.C.1    Baltrusch, M.2    Buck, F.3    Wolter, F.P.4    Heinz, E.5
  • 72
    • 51849178119 scopus 로고
    • Toxicity of cycads
    • M. G. Whiting 1963 Toxicity of cycads Economic Botany 17 271 302
    • (1963) Economic Botany , vol.17 , pp. 271-302
    • Whiting, M.G.1
  • 73
    • 0041475740 scopus 로고    scopus 로고
    • Decrease in glial glutamate transporter variants and excitatory amino acid receptor down-regulation in a murine model of ALS-PDC
    • J. M. Wilson I. Khabazian D. V. Pow U. K. Craig C. A. Shaw 2003 Decrease in glial glutamate transporter variants and excitatory amino acid receptor down-regulation in a murine model of ALS-PDC Neuromolecular Medicine 3 105 118
    • (2003) Neuromolecular Medicine , vol.3 , pp. 105-118
    • Wilson, J.M.1    Khabazian, I.2    Pow, D.V.3    Craig, U.K.4    Shaw, C.A.5
  • 76
    • 4344652091 scopus 로고    scopus 로고
    • Quantitative measurement of neurodegeneration in an ALS-PDC model using MR microscopy
    • J. M. Wilson M. S. Petrik S. C. Grant S. J. Blackband J. Lai C. A. Shaw 2004 Quantitative measurement of neurodegeneration in an ALS-PDC model using MR microscopy Neuroimage 23 336 343
    • (2004) Neuroimage , vol.23 , pp. 336-343
    • Wilson, J.M.1    Petrik, M.S.2    Grant, S.C.3    Blackband, S.J.4    Lai, J.5    Shaw, C.A.6
  • 81
    • 34250727443 scopus 로고    scopus 로고
    • Late appearance of glutamate transporter defects in a murine model of ALS-parkinsonism dementia complex
    • Wilson, J. M., & Shaw, C. A. (2006). Late appearance of glutamate transporter defects in a murine model of ALS-parkinsonism dementia complex. Neurochemsitry International, 50, 1067-1077.
    • (2006) Neurochemsitry International , vol.50 , pp. 1067-1077
    • Wilson, J.M.1    Shaw, C.A.2


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