Isolation of various forms of sterol β-D-glucoside from the seed of Cycas circinalis: Neurotoxicity and implications for ALS-parkinsonism dementia complex

Journal of Neurochemistry

Volumn 82, Issue 3, 2002, Pages 516-528

  Khabazian, I ^a   Bains, J S ^a   Williams, D E ^a   Cheung, J ^a   Wilson, J M B ^a   Pasqualotto, B A ^a   Pelech, S L ^a,c   Andersen, R J ^a   Wang, Y T ^a   Liu, L ^a   Nagai, A ^a   Kim, S U ^a   Craig, U K ^b   Shaw, C A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF GUAM   (Guam)

^c Kinexus Bioinformatics Corporation   (Canada)

Author keywords

ALS parkinsonism dementia complex; Cycad; Glutamate release; Neurotoxicity; NMDA receptor; Sterol D glucoside

Indexed keywords

CASPASE 3; CYCAS CIRCINALIS EXTRACT; EXCITOTOXIN; GLUCOSIDE; GLUTAMIC ACID; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTOXIN; PLANT EXTRACT; PROTEIN KINASE; STEROL BETA DEXTRO GLUCOSIDE; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BIOASSAY; BRAIN SLICE; CELL DEATH; CONTROLLED STUDY; CYCAS CIRCINALIS; DEPOLARIZATION; ENZYME ACTIVITY; FLOUR; GUAM; HYPOTHESIS; MALE; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROTOXICITY; NICK END LABELING; NONHUMAN; OUTCOMES RESEARCH; PARKINSON DISEASE; PLANT SEED; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; TREE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; BIOLOGICAL ASSAY; CELLS, CULTURED; CEREBRAL CORTEX; CHOLESTEROL; CYCAS; DEMENTIA; GLUCOSE; GLUCOSIDES; GUAM; HUMANS; MALE; MICE; NEURONS; NEUROTOXINS; PARKINSONIAN DISORDERS; PATCH-CLAMP TECHNIQUES; PHYTOSTEROLS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SEEDS; SITOSTEROLS; STIGMASTEROL;

ANIMALIA; CYCAS; CYCAS CIRCINALIS;

EID: 0036326421     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00976.x     Document Type: Article

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