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Volumn 180, Issue 5, 2008, Pages 3375-3382

Antigen-specific CD4+ T cells produce sufficient IFN-γ to mediate robust protective immunity against genital Chlamydia muridarum infection

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEINASE; BACTERIAL VACCINE; BETA 2 MICROGLOBULIN; CPA FACTOR; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; EPITOPE; OLIGODEOXYRIBONUCLEOTIDE;

EID: 49149088390     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.5.3375     Document Type: Article
Times cited : (82)

References (43)
  • 1
    • 13444301093 scopus 로고    scopus 로고
    • Immunology of Chlamydia infection: Implications for a Chlamydia trachomatis vaccine
    • Brunham, R. C., and J. Rey-Ladino. 2005. Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine. Nat. Rev. Immunol. 5: 149-161.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 149-161
    • Brunham, R.C.1    Rey-Ladino, J.2
  • 2
    • 0036263421 scopus 로고    scopus 로고
    • Immunity to murine chlamydial genital infection
    • Morrison, R. P., and H. D. Caldwell. 2002. Immunity to murine chlamydial genital infection. Infect. Immun. 70: 2741-2751.
    • (2002) Infect. Immun , vol.70 , pp. 2741-2751
    • Morrison, R.P.1    Caldwell, H.D.2
  • 3
    • 27744587346 scopus 로고    scopus 로고
    • The unexpected impact of a Chlamydia trachomatis infection control program on susceptibility to reinfection
    • Brunham, R. C., B. Pourbohloul, S. Mak, R. White, and M. L. Rekart. 2005. The unexpected impact of a Chlamydia trachomatis infection control program on susceptibility to reinfection. J. Infect. Dis. 192: 1836-1844.
    • (2005) J. Infect. Dis , vol.192 , pp. 1836-1844
    • Brunham, R.C.1    Pourbohloul, B.2    Mak, S.3    White, R.4    Rekart, M.L.5
  • 4
    • 0026047282 scopus 로고
    • Role of L3T4-bearing T-cell populations in experimental murine chlamydial salpingitis
    • Landers, D. V., K. Erlich, M. Sung, and J. Schachter. 1991. Role of L3T4-bearing T-cell populations in experimental murine chlamydial salpingitis. Infect. Immun. 59: 3774-3777.
    • (1991) Infect. Immun , vol.59 , pp. 3774-3777
    • Landers, D.V.1    Erlich, K.2    Sung, M.3    Schachter, J.4
  • 5
    • 0029162732 scopus 로고
    • + T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract
    • + T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract. Infect. Immun. 63: 3302-3308.
    • (1995) Infect. Immun , vol.63 , pp. 3302-3308
    • Su, H.1    Caldwell, H.D.2
  • 7
    • 0027884892 scopus 로고
    • Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, Th1 lymphocyte clone
    • Igietseme, J. U., K. H. Ramsey, D. M. Magee, D. M. Williams, T. J. Kincy, and R. G. Rank. 1993. Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, Th1 lymphocyte clone. Reg. Immunol. 5: 317-324.
    • (1993) Reg. Immunol , vol.5 , pp. 317-324
    • Igietseme, J.U.1    Ramsey, K.H.2    Magee, D.M.3    Williams, D.M.4    Kincy, T.J.5    Rank, R.G.6
  • 8
    • 0026011410 scopus 로고
    • Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines
    • Ramsey, K. H., and R. G. Rank. 1991. Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines. Infect. Immun. 59: 925-931.
    • (1991) Infect. Immun , vol.59 , pp. 925-931
    • Ramsey, K.H.1    Rank, R.G.2
  • 9
    • 0034114441 scopus 로고    scopus 로고
    • In situ analysis of the evolution of the primary immune response in murine Chlamydia trachomatis genital tract infection
    • Morrison, S. G., and R. P. Morrison. 2000. In situ analysis of the evolution of the primary immune response in murine Chlamydia trachomatis genital tract infection. Infect. Immun. 68: 2870-2879.
    • (2000) Infect. Immun , vol.68 , pp. 2870-2879
    • Morrison, S.G.1    Morrison, R.P.2
  • 10
    • 0030773745 scopus 로고    scopus 로고
    • + T cells to the genital tract following intravaginal infection with Chlamydia trachomatis
    • + T cells to the genital tract following intravaginal infection with Chlamydia trachomatis. Infect. Immun. 65: 5198-5208.
    • (1997) Infect. Immun , vol.65 , pp. 5198-5208
    • Kelly, K.A.1    Rank, R.G.2
  • 11
    • 0028967628 scopus 로고
    • Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis
    • Cain, T. K., and R. G. Rank. 1995. Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect. Immun. 63: 1784-1789.
    • (1995) Infect. Immun , vol.63 , pp. 1784-1789
    • Cain, T.K.1    Rank, R.G.2
  • 12
    • 0031112653 scopus 로고    scopus 로고
    • Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways
    • Perry, L. L., K. Feilzer, and H. D. Caldwell. 1997. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways. J. Immunol. 158: 3344-3352.
    • (1997) J. Immunol , vol.158 , pp. 3344-3352
    • Perry, L.L.1    Feilzer, K.2    Caldwell, H.D.3
  • 13
    • 0032521028 scopus 로고    scopus 로고
    • Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice
    • Perry, L. L., K. Feilzer, J. L. Portis, and H. D. Caldwell. 1998. Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice. J. Immunol. 160: 2905-2914.
    • (1998) J. Immunol , vol.160 , pp. 2905-2914
    • Perry, L.L.1    Feilzer, K.2    Portis, J.L.3    Caldwell, H.D.4
  • 14
    • 0033559566 scopus 로고    scopus 로고
    • Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-γ-mediated inhibition
    • Perry, L. L., H. Su, K. Feilzer, R. Messer, S. Hughes, W. Whitmire, and H. D. Caldwell. 1999. Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-γ-mediated inhibition. J. Immunol. 162: 3541-3548.
    • (1999) J. Immunol , vol.162 , pp. 3541-3548
    • Perry, L.L.1    Su, H.2    Feilzer, K.3    Messer, R.4    Hughes, S.5    Whitmire, W.6    Caldwell, H.D.7
  • 16
    • 0033015703 scopus 로고    scopus 로고
    • Clearance of Chlamydia trachomatis from the murine genital mucosa does not require perforin-mediated cytolysis or Fas-mediated apoptosis
    • Perry, L. L., K. Feilzer, S. Hughes, and H. D. Caldwell. 1999. Clearance of Chlamydia trachomatis from the murine genital mucosa does not require perforin-mediated cytolysis or Fas-mediated apoptosis. Infect. Immun. 67: 1379-1385.
    • (1999) Infect. Immun , vol.67 , pp. 1379-1385
    • Perry, L.L.1    Feilzer, K.2    Hughes, S.3    Caldwell, H.D.4
  • 17
    • 33846849093 scopus 로고    scopus 로고
    • Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous γ interferon production
    • Murthy, A. K., J. P. Chambers, P. A. Meier, G. Zhong, and B. P. Arulanandam. 2007. Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous γ interferon production. Infect. Immun. 75: 666-676.
    • (2007) Infect. Immun , vol.75 , pp. 666-676
    • Murthy, A.K.1    Chambers, J.P.2    Meier, P.A.3    Zhong, G.4    Arulanandam, B.P.5
  • 18
    • 0030988438 scopus 로고    scopus 로고
    • Dissemination of Chlamydia trachomatis chronic genital tract infection in γ interferon gene knockout mice
    • Cotter, T. W., K. H. Ramsey, G. S. Miranpuri, C. E. Poulsen, and G. I. Byrne. 1997. Dissemination of Chlamydia trachomatis chronic genital tract infection in γ interferon gene knockout mice. Infect. Immun. 65: 2145-2152.
    • (1997) Infect. Immun , vol.65 , pp. 2145-2152
    • Cotter, T.W.1    Ramsey, K.H.2    Miranpuri, G.S.3    Poulsen, C.E.4    Byrne, G.I.5
  • 19
    • 0032830635 scopus 로고    scopus 로고
    • Role of γ interferon in controlling murine chlamydial genital tract infection
    • Ito, J. I., and J. M. Lyons. 1999. Role of γ interferon in controlling murine chlamydial genital tract infection. Infect. Immun. 67: 5518-5521.
    • (1999) Infect. Immun , vol.67 , pp. 5518-5521
    • Ito, J.I.1    Lyons, J.M.2
  • 20
    • 0031020913 scopus 로고    scopus 로고
    • Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in γ interferon receptor-deficient mice despite a strong local immunoglobulin A response
    • Johansson, M., K. Schon, M. Ward, and N. Lycke. 1997. Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in γ interferon receptor-deficient mice despite a strong local immunoglobulin A response. Infect. Immun. 65: 1032-1044.
    • (1997) Infect. Immun , vol.65 , pp. 1032-1044
    • Johansson, M.1    Schon, K.2    Ward, M.3    Lycke, N.4
  • 21
    • 0026660316 scopus 로고
    • Effect of γ interferon on resolution of murine chlamydial genital infection
    • Rank, R. G., K. H. Ramsey, E. A. Pack, and D. M. Williams. 1992. Effect of γ interferon on resolution of murine chlamydial genital infection. Infect. Immun. 60: 4427-4429.
    • (1992) Infect. Immun , vol.60 , pp. 4427-4429
    • Rank, R.G.1    Ramsey, K.H.2    Pack, E.A.3    Williams, D.M.4
  • 22
    • 0032751041 scopus 로고    scopus 로고
    • IFN-γ knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection
    • Wang, S., Y. Fan, R. C. Brunham, and X. Yang. 1999. IFN-γ knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection. Eur. J. Immunol. 29: 3782-3792.
    • (1999) Eur. J. Immunol , vol.29 , pp. 3782-3792
    • Wang, S.1    Fan, Y.2    Brunham, R.C.3    Yang, X.4
  • 23
    • 0035896736 scopus 로고    scopus 로고
    • Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors
    • Zhong, G., P. Fan, H. Ji, F. Dong, and Y. Huang. 2001. Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors. J. Exp. Med. 193: 935-942.
    • (2001) J. Exp. Med , vol.193 , pp. 935-942
    • Zhong, G.1    Fan, P.2    Ji, H.3    Dong, F.4    Huang, Y.5
  • 24
    • 3042546262 scopus 로고    scopus 로고
    • Cleavage of host keratin 8 by a Chlamydia-secreted protease
    • Dong, F., H. Su, Y. Huang, Y. Zhong, and G. Zhong. 2004. Cleavage of host keratin 8 by a Chlamydia-secreted protease. Infect. Immun. 72: 3863-3868.
    • (2004) Infect. Immun , vol.72 , pp. 3863-3868
    • Dong, F.1    Su, H.2    Huang, Y.3    Zhong, Y.4    Zhong, G.5
  • 25
    • 15544378836 scopus 로고    scopus 로고
    • Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species
    • Dong, F., Y. Zhong, B. Arulanandam, and G. Zhong. 2005. Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species. Infect. Immun. 73: 1868-1872.
    • (2005) Infect. Immun , vol.73 , pp. 1868-1872
    • Dong, F.1    Zhong, Y.2    Arulanandam, B.3    Zhong, G.4
  • 26
    • 2942598439 scopus 로고    scopus 로고
    • Cleavage-dependent activation of a Chlamydia-secreted protease
    • Dong, F., M. Pirbhai, Y. Zhong, and G. Zhong. 2004. Cleavage-dependent activation of a Chlamydia-secreted protease. Mol. Microbiol. 52: 1487-1494.
    • (2004) Mol. Microbiol , vol.52 , pp. 1487-1494
    • Dong, F.1    Pirbhai, M.2    Zhong, Y.3    Zhong, G.4
  • 27
    • 33644764765 scopus 로고    scopus 로고
    • Profiling of human antibody responses to Chlamydia trachomatis urogenital tract infection using microplates arrayed with 156 chlamydial fusion proteins
    • Sharma, J., Y. Zhong, F. Dong, J. M. Piper, G. Wang, and G. Zhong. 2006. Profiling of human antibody responses to Chlamydia trachomatis urogenital tract infection using microplates arrayed with 156 chlamydial fusion proteins. Infect. Immun. 74: 1490-1499.
    • (2006) Infect. Immun , vol.74 , pp. 1490-1499
    • Sharma, J.1    Zhong, Y.2    Dong, F.3    Piper, J.M.4    Wang, G.5    Zhong, G.6
  • 28
    • 21544450829 scopus 로고    scopus 로고
    • Inhibition of proteolytic activity of a chlamydial proteasome/protease-like activity factor by antibodies from humans infected with Chlamydia trachomatis
    • Sharma, J., F. Dong, M. Pirbhai, and G. Zhong. 2005. Inhibition of proteolytic activity of a chlamydial proteasome/protease-like activity factor by antibodies from humans infected with Chlamydia trachomatis. Infect. Immun. 73: 4414-4419.
    • (2005) Infect. Immun , vol.73 , pp. 4414-4419
    • Sharma, J.1    Dong, F.2    Pirbhai, M.3    Zhong, G.4
  • 29
    • 9244258599 scopus 로고    scopus 로고
    • Human antibody responses to a Chlamydia-secreted protease factor
    • Sharma, J., A. M. Bosnic, J. M. Piper, and G. Zhong. 2004. Human antibody responses to a Chlamydia-secreted protease factor. Infect. Immun. 72: 7164-7171.
    • (2004) Infect. Immun , vol.72 , pp. 7164-7171
    • Sharma, J.1    Bosnic, A.M.2    Piper, J.M.3    Zhong, G.4
  • 31
    • 34247163593 scopus 로고    scopus 로고
    • Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection
    • Cong, Y., M. Jupelli, M. N. Guentzel, G. Zhong, A. K. Murthy, and B. P. Arulanandam. 2007. Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection. Vaccine 25: 3773-3780.
    • (2007) Vaccine , vol.25 , pp. 3773-3780
    • Cong, Y.1    Jupelli, M.2    Guentzel, M.N.3    Zhong, G.4    Murthy, A.K.5    Arulanandam, B.P.6
  • 32
    • 33845482256 scopus 로고    scopus 로고
    • Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele
    • Murthy, A. K., Y. Cong, C. Murphey, M. N. Guentzel, T. G. Forsthuber, G. Zhong, and B. P. Arulanandam. 2006. Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect. Immun. 74: 6722-6729.
    • (2006) Infect. Immun , vol.74 , pp. 6722-6729
    • Murthy, A.K.1    Cong, Y.2    Murphey, C.3    Guentzel, M.N.4    Forsthuber, T.G.5    Zhong, G.6    Arulanandam, B.P.7
  • 33
    • 8344235864 scopus 로고    scopus 로고
    • Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice
    • Murthy, A. K., J. Sharma, J. J. Coalson, G. Zhong, and B. P. Arulanandam. 2004. Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice. Cell Immunol. 230: 56-64.
    • (2004) Cell Immunol , vol.230 , pp. 56-64
    • Murthy, A.K.1    Sharma, J.2    Coalson, J.J.3    Zhong, G.4    Arulanandam, B.P.5
  • 34
    • 34548264628 scopus 로고    scopus 로고
    • Quantifying lymphocyte kinetics in vivo using carboxy-fluorescein diacetate succinimidyl ester (CFSE)
    • Asquith, B., C. Debacq, A. Florins, N. Gillet, T. Sanchez-Alcaraz, A. Mosley, and L. Willems. 2006. Quantifying lymphocyte kinetics in vivo using carboxy-fluorescein diacetate succinimidyl ester (CFSE). Proc. Biol. Sci. 273: 1165-1171.
    • (2006) Proc. Biol. Sci , vol.273 , pp. 1165-1171
    • Asquith, B.1    Debacq, C.2    Florins, A.3    Gillet, N.4    Sanchez-Alcaraz, T.5    Mosley, A.6    Willems, L.7
  • 35
    • 0034699367 scopus 로고    scopus 로고
    • Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons, A. B. 2000. Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J. Immunol. Methods 243: 147-154.
    • (2000) J. Immunol. Methods , vol.243 , pp. 147-154
    • Lyons, A.B.1
  • 36
    • 34250863792 scopus 로고    scopus 로고
    • Tumor necrosis factor-α antagonism by the murine tumor necrosis factor-α receptor 2-Fc fusion protein exacerbates histoplasmosis in mice
    • Deepe, G. S. 2007. Tumor necrosis factor-α antagonism by the murine tumor necrosis factor-α receptor 2-Fc fusion protein exacerbates histoplasmosis in mice. J. Interferon Cytokine Res. 27: 471-480.
    • (2007) J. Interferon Cytokine Res , vol.27 , pp. 471-480
    • Deepe, G.S.1
  • 37
    • 36348929384 scopus 로고    scopus 로고
    • TNF controls the infiltration of dendritic cells into the site of Leishmania major infection
    • Ritter, U., A. Lechner, K. Scharl, Z. Kiafard, J. Zwirner, and H. Korner. 2008. TNF controls the infiltration of dendritic cells into the site of Leishmania major infection. Med. Microbiol. Immunol. 197: 29-37.
    • (2008) Med. Microbiol. Immunol , vol.197 , pp. 29-37
    • Ritter, U.1    Lechner, A.2    Scharl, K.3    Kiafard, Z.4    Zwirner, J.5    Korner, H.6
  • 39
    • 0031935085 scopus 로고    scopus 로고
    • Neither interleukin-6 nor inducible nitric oxide synthase is required for clearance of Chlamydia trachomatis from the murine genital tract epithelium
    • Perry, L. L., K. Feilzer, and H. D. Caldwell. 1998. Neither interleukin-6 nor inducible nitric oxide synthase is required for clearance of Chlamydia trachomatis from the murine genital tract epithelium. Infect. Immun. 66: 1265-1269.
    • (1998) Infect. Immun , vol.66 , pp. 1265-1269
    • Perry, L.L.1    Feilzer, K.2    Caldwell, H.D.3
  • 40
    • 0033856173 scopus 로고    scopus 로고
    • Does inhibition of tumor necrosis factor α affect chlamydial genital tract infection in mice and guinea pigs?
    • Darville, T., C. W. Andrews, Jr., and R. G. Rank. 2000. Does inhibition of tumor necrosis factor α affect chlamydial genital tract infection in mice and guinea pigs? Infect. Immun. 68: 5299-5305.
    • (2000) Infect. Immun , vol.68 , pp. 5299-5305
    • Darville, T.1    Andrews Jr., C.W.2    Rank, R.G.3
  • 43
    • 0038669151 scopus 로고    scopus 로고
    • Cross-presentation of antigens by dendritic cells
    • Belz, G. T., F. R. Carbone, and W. R. Heath. 2002. Cross-presentation of antigens by dendritic cells. Crit. Rev. Immunol. 22: 439-448.
    • (2002) Crit. Rev. Immunol , vol.22 , pp. 439-448
    • Belz, G.T.1    Carbone, F.R.2    Heath, W.R.3


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