Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice

Journal of Immunology

Volumn 160, Issue 6, 1998, Pages 2905-2914

  Perry, Linda L ^a,b   Feilzer, Karen ^a   Portis, John L ^a   Caldwell, Harlan D ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; FEMALE; FEMALE GENITAL TRACT INFECTION; IMMUNE RESPONSE; INTESTINE MUCOSA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEXUALLY TRANSMITTED DISEASE; T LYMPHOCYTE ACTIVATION; VAGINA MUCOSA;

ANIMALS; CELL ADHESION MOLECULES; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; FEMALE; GENITALIA, FEMALE; IMMUNOGLOBULINS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTEGRINS; INTERCELLULAR ADHESION MOLECULE-1; INTESTINAL MUCOSA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUCOPROTEINS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0032521028     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Schachter, J. 1989. Pathogenesis of chlamydial infections. Pathol. Immunopathol. Res. 8:206.
2. Barteneva, N., I. Theodor, E. M. Peterson, and L. M. de la Maza. 1996. Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection. Infect. Immun. 64:4830.
3. Morrison, R. P., K. Feilzer, and D. B. Tumas. 1995. Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection. Infect. Immun. 63:4661.
4. Perry, L. L., K. Feilzer, and H. D. Caldwell. 1997. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways. J. Immunol. 158:3344.
5. Ramsey, K. H., L. S. F. Soderberg, and R. G. Rank. 1988. Resolution of chlamydial genital infection in B-cell-deficient mice and immunity to reinfection. Infect. Immun. 56:1320.
6. Su, H., K. Feilzer, H. D. Caldwell, and R. P. Morrison. 1997. Chlamydia trachomatis genital tract infection of antibody-deficient gene knockout mice. Infect. Immun. 65:1993.
7. Cain, T. K., and R. G. Rank. 1995. Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect. Immun. 63:1784.
8. 1 lymphocyte clone. Reg. Immunol. 5:317.
9. Tamraz, S., T. Arrhenius, A. Chiem, M. J. Forrest, F. C. A. Gaeta, Y.-B. He, J. Lei, A. Maewal, M. L. Phillips, L. W. Vollger, and M. J. Elices. 1995. Treatment of delayed-type hypersensitivity with inhibitors of the VLA-4 integrin. Springer Semin. Immunopathol. 16:437.
10. Silber, A., W. Newman, V. G. Sasseville, D. Pauley, D. Beall, D. G. Walsh, and D. J. Ringler. 1994. Recruitment of lymphocytes during cutaneous delayed hypersensitivity in nonhuman primates is dependent on E-selectin and vascular cell adhesion molecule 1. J. Clin. Invest. 93:1554.
11. Engelhardt, B., F. K. Conley, and E. C. Butcher. 1994. Cell adhesion molecules on vessels during inflammation in the mouse central nervous system. J. Neuroimmunol. 51:199.
12. 7 integrins and memory differentiation. J. Immunol. 156:3727.
13. Parr, M. B., and E. L. Parr. 1991. Langerhans cells and T lymphocyte subsets in the murine vagina and cervix. Biol. Reprod. 44:491.
14. Nandi, D., and J. P. Allison. 1993. Characterization of neutrophils and T lymphocytes associated with the murine vaginal epithelium. Reg. Immunol. 5:332.
15. McGhee, J. R., J. Mestecky, M. T. Dertzbaugh, J. H. Eldridge, M. Hirasawa, and H. Kiyono. 1992. The mucosal immune system: from fundamental concepts to vaccine development. Vaccine 10:75.
16. Guy-Grand, D., and P. Vassalli. 1993. Gut intraepithelial T lymphocytes. Curr. Opin. Immunol. 5:247.
17. Caldwell, H. D., J. Kromhout, and J. Schachter. 1981. Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis. Infect. Immun. 31:1161.
18. Lefrancois, L., and N. Lycke. 1996. Isolation of mouse small intestinal intraepithelial lymphocytes. In Current Protocols in Immunology, Vol. 1. J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach and W. Strober, Eds. John Wiley and Sons, New York, p. 3.19.1.
19. + intraepithelial lymphocytes. Nature 333:855.
20. + lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J. Exp. Med. 173:471.
21. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
22. Steinhoff, G., M. Behrend, B. Schrader, A. M. Duijvestijn, and K. Wonigeit. 1993. Expression patterns of leukocyte adhesion ligand molecules on human liver endothelia. Am. J. Pathol. 142:481.
23. 7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined. Immunity 3:99.
24. Streeter, P. R., E. L. Berg, B. T. N. Rouse, R. F. Bargatze, and E. C. Butcher. 1988. A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331:41.
25. 7 integrin. Nature 372:190.
26. + T cells in vivo. J. Immunol. 154:5684.
27. Bilsland, C. A. G., M. S. Diamond, and T. A. Springer. 1994. The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b: activation by a heterologous β subunit and localization of a ligand recognition site to the I domain. J. Immunol. 152:4582.
28. 7 integrins on thymocytes, intestinal epithelial lymphocytes and peripheral lymphocytes. Eur. J. Immunol. 26:897.
29. Sprent, J. 1994. T and B memory cells. Cell 76:315.
30. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
31. - (naive) T cells roll efficiently on E- and P-selectin and vascular cell adhesion molecule-1 under flow. J. Immunol. 158:3640.
32. + T cells. J. Immunol. 155:1873.
33. Engelhardt, B., F. K. Conley, P. J. Kilshaw, and E. C. Butcher. 1995. Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1. Int. Immunol. 7:481.
34. Kuhn, R., J. Lohler, D. Rennick, K. Rajewsky, and W. Muller. 1994. IL-10 deficient mice develop chronic enterocolitis. Cell 75:263.
35. + T cell down-regulation in human intestinal mucosa: evidence for intestinal tolerance to luminal bacterial antigens. J. Immunol. 158:3626.
36. Picker, L. J., R. J. Martin, A. Trumble, L. S. Newman, P. A. Collins, P. R. Bergstresser, and D. Y. Leung. 1994. Differential expression of lymphocyte homing receptors by human memory/effector T cells in pulmonary versus cutaneous immune effector sites. Eur. J. Immunol. 24:1269.
37. Holmgren, J., C. Czerkinsky, N. Lycke, and A.-M. Svennerholm. 1992. Mucosal immunity: implications for vaccine development. Immunobiology 184:157.
38. McDermott, M. R., and J. Bienenstock. 1979. Evidence for a common mucosal immunologic system. I. Migration of B immunoblasts into intestinal, respiratory, and genital tissues. J. Immunol. 122:1892.
39. Cui, Z.-D., L. J. LaScolea, Jr., J. Fisher, and P. L. Ogra. 1989. Immunoprophylaxis of Chlamydia trachomatis lymphogranuloma venereum pneumonitis in mice by oral immunization. Infect. Immun. 57:739.
40. Picker, L. J., and E. C. Butcher. 1992. Physiological and molecular mechanisms of lymphocyte homing. Annu. Rev. Immunol. 10:561.
41. Kantele, A., J. M. Kantele, E. Savilahti, M. Westerholm, H. Arvilommi, A. Lazarovits, E. C. Butcher, and P. H. Makela. 1997. Homing potentials of circulating lymphocytes in humans depend on the site of activation: oral, but not parenteral, typhoid vaccination induces circulating antibody-secreting cells that all bear homing receptors directing them to the gut. J. Immunol. 158:574.
42. Tuffrey, M., F. Alexander, W. Conlan, C. Woods, and M. Ward. 1992. Heterotypic protection of mice against chlamydial salpingitis and colonization of the lower genital tract with a human serovar F isolate of Chlamydia trachomatis by prior immunization with recombinant serovar L1 major outer-membrane protein. J. Gen. Microbiol. 138:1707.