Does inhibition of tumor necrosis factor alpha affect chlamydial genital tract infection in mice and guinea pigs?

Infection and Immunity

Volumn 68, Issue 9, 2000, Pages 5299-5305

  Darville, T ^a   Andrews C W , Jr ^a   Rank, R G ^a  

^a ARKANSAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PSITTACI; GENITAL TRACT INFECTION; GUINEA PIG; HOST RESISTANCE; INFLAMMATORY CELL; MACROPHAGE; MONOCYTE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; UTERINE ENDOCERVIX;

ANIMALS; CHLAMYDIA INFECTIONS; FEMALE; GENITAL DISEASES, FEMALE; INTERFERON TYPE II; MICE; MICE, INBRED C57BL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033856173     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.9.5299-5305.2000     Document Type: Article

References (40)

1. Macrophage inflammatory proteins MIP-1 and MIP-2 are involved in T cell-mediated neutrophil recruitment
2. Inhibition of tumor necrosis factor-alpha alters resistance to Mycobacterium avium complex infection in mice
3. Target tissues associated with genital infection of female guinea pigs by the chlamydial agent of guinea pig inclusion conjunctivitis
4. Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection
5. Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain
6. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
7. Hierarchical control of lymphocyte survival
8. Neutrophils and tumor necrosis factor-alpha are important for controlling early gastrointestinal stages of experimental murine listeriosis
9. Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice
10. Mouse strain-dependent variation in the course and outcome of chlamydial genital tract infection is associated with differences in host response
11. Tumor necrosis factor-alpha activity in genital tract secretions of guinea pigs infected with chlamydiae
12. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
13. Cell death mechanisms and the immune system
14. Involvement of two types of TNF receptor in TNF-alpha induced neutrophil apoptosis
15. Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level
16. Initial route of antigen administration alters the T-cell cytokine profile produced in response to the mouse pneumonitis biovar of Chlamydia trachomatis following genital infection
17. Inhibition of Chlamydia trachomatis replication in HEp-2 cells by human monocyte-derived macrophages
18. Complement activation and stimulation of chemotaxis by Chlamydia trachomatis
19. Tumor necrosis factor-alpha: Central regulatory cytokine in the induction of macrophage antimicrobial activities
20. Effects of various doses of estradiol on chlamydial genital infection in ovari-ectomized guinea pigs
21. A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
22. Effect of Chlamydia trachomatis infection and subsequent TNFα secretion on apoptosis in the murine genital tract
23. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways
24. Neither interleukin-6 nor inducible nitric oxide synthase is required for clearance of Chlamydia trachomatis from the murine genital tract epithelium
25. Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-γ-mediated inhibition
26. Differential nitric oxide production by macrophages from mice and guinea pigs infected with virulent and avirulent Legionella pneumophila serogroup 1
27. Animal models for urogenital infections
28. Specific effect of estradiol on the genital mucosal antibody response in chlamydial ocular and genital infections
29. Susceptibility to reinfection after a primary chlamydial genital infection
30. Ascending genital tract infection as a common consequence of vaginal inoculation with the guinea pig inclusion conjunctivitis agent in normal guinea pigs
31. Pathogenesis of endometritis and salpingitis in a guinea pig model of chlamydial genital infection
32. Influence of the estrous cycle on the development of upper genital tract pathology as a result of chlamydial infection in the guinea pig model of pelvic inflammatory, disease
33. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis
34. Inhibition of Chlamydia trachomatis growth by recombinant tumor necrosis factor
35. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages
36. Role and effect of TNF-alpha in experimental visceral leishmaniasis
37. A role for interleukin 6 in host defense against Chlamydia trachomatis
38. Humoral and cellular immunity in secondary infection due to murine Chlamydia trachomatis
39. A role in vivo for tumor necrosis factor alpha in host defense against Chlamydia trachomatis
40. Caspases mediate tumor necrosis factor-alpha-induced neutrophil apoptosis and downregulation of reactive oxygen production