TNF controls the infiltration of dendritic cells into the site of Leishmania major infection

Medical Microbiology and Immunology

Volumn 197, Issue 1, 2008, Pages 29-37

  Ritter, Uwe ^a,b,c   Lechner, Anja ^c   Scharl, Katja ^a   Kiafard, Ziba ^d   Zwirner, Jörg ^d   Körner, Heinrich ^e  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e JAMES COOK UNIVERSITY   (Australia)

Author keywords

Chemokines; Dendritic cells; Leishmania; Leishmania parasites; Lymph node; Skin; TNF

Indexed keywords

GAMMA INTERFERON; PARASITE ANTIGEN; RECOMBINANT TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; C57BL 6 MOUSE; CELL INFILTRATION; DENDRITIC CELL; ENVIRONMENT; FOOT PAD; IMMUNITY; INFLAMMATION; LEISHMANIA MAJOR; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTOZOAL INFECTION; SKIN; SURVIVAL; TH1 CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD11C; ANTIGENS, CD45; CELL MOVEMENT; CHEMOKINE CCL21; DENDRITIC CELLS; FLOW CYTOMETRY; FOOT; IMMUNITY, CELLULAR; INFLAMMATION; INTERFERON TYPE II; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LEUKOCYTES; LYMPH NODES; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; SKIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 36348929384     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00430-007-0056-z     Document Type: Article

References (34)

1. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K (2000) Immunobiology of dendritic cells. Annu Rev Immunol 18:767-811
2. Kelsall BL, Biron CA, Sharma O, Kaye PM (2002) Dendritic cells at the host-pathogen interface. Nat Immunol 3:699-702
3. Serbina NV, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer EG (2003) TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19:59-70
4. Martin-Fontecha A, Sebastiani S, Hopken UE, Uguccioni M, Lipp M, Lanzavecchia A, Sallusto F (2003) Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med 198:615-621
5. Ritter U, Mattner J, Rocha JS, Bogdan C, Korner H (2004) The control of Leishmania (Leishmania) major by TNF in vivo is dependent on the parasite strain. Microbes Infect 6:559-565
6. Ritter U, Meissner A, Ott J, Korner H (2003) Analysis of the maturation process of dendritic cells deficient for TNF and lymphotoxin-alpha reveals an essential role for TNF. J Leukoc Biol 74:216-222
7. Ohl L, Mohaupt M, Czeloth N, Hintzen G, Kiafard Z, Zwirner J, Blankenstein T, Henning G, Forster R (2004) CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21:279-288
8. Sacks D, Noben-Trauth N (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2:845-858
9. Solbach W, Laskay T (2000) The host response to Leishmania infection. Adv Immunol 74:275-317
10. Diefenbach A, Schindler H, Donhauser N, Lorenz E, Laskay T, MacMicking J, Röllinghoff M, Gresser I, Bogdan C (1998) Type 1 interferon (IFN-α/β) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite. Immunity 8:77-87
11. Scharton-Kersten T, Afonso LC, Wysocka M, Trinchieri G, Scott P (1995) IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J Immunol 154:5320-5330
12. Malherbe L, Filippi C, Julia V, Foucras G, Moro M, Appel H, Wucherpfennig K, Guery JC, Glaichenhaus N (2000) Selective activation and expansion of high-affinity CD4+ T cells in resistant mice upon infection with Leishmania major. Immunity 13:771-782
13. Himmelrich H, Launois P, Maillard I, Biedermann T, Tacchini-Cottier F, Locksley RM, Rocken M, Louis JA (2000) In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J Immunol 164:4819-4825
14. Wilhelm P, Ritter U, Labbow S, Donhauser N, Rollinghoff M, Bogdan C, Korner H (2001) Rapidly fatal leishmaniasis in resistant C57BL/6 mice lacking TNF. J Immunol 166:4012-4019
15. Leon B, Lopez-Bravo M, Ardavin C (2007) Monocyte-derived dendritic cells formed at the infection site control the induction of protective T Helper 1 responses against Leishmania. Immunity 26:519-531
16. Körner H, Cook M, Riminton DS, Lemckert FA, Hoek R, Ledermann B, Köntgen F, Fazekas de St Groth B, Sedgwick JD (1997) Distinct roles for lymphotoxin-α and tumour necrosis factor in lymphoid tissue organogenesis and spatial organisation defined in gene targeted C57BL/6 Mice. Eur J Immunol 27:2600-2609
17. Wilhelm P, Riminton DS, Ritter U, Lemckert FA, Scheidig C, Hoek R, Sedgwick JD, Korner H (2002) Membrane lymphotoxin contributes to anti-leishmanial immunity by controlling structural integrity of lymphoid organs. Eur J Immunol 32:1993-2003
18. Solbach W, Forberg K, Kammerer E, Bogdan C, Röllinghoff M (1986) Suppressive effect of cyclosporin A on the development of Leishmania tropica-induced lesions in genetically susceptible BALB/c mice. J Immunol 137:702-711
19. Wilhelm P, Ritter U, Labbow S, Donhauser N, Röllinghoff M, Bogdan C, Körner H (2001) Rapidly fatal Leishmaniasis in resistant C57BL/6 mice lacking TNF. J Immunol 166:4012-4019
20. Ritter U, Mattner J, Rocha JS, Bogdan C, Körner H (2004) The control of Leishmania (Leishmania) major by TNF in vivo is dependent on the parasite strain. Microbes Infect 6:559-565
21. Higuchi R, Fockler C, Dollinger G, Watson R (1993) Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y) 11:1026-1030
22. Ponchel F, Toomes C, Bransfield K, Leong FT, Douglas SH, Field SL, Bell SM, Combaret V, Puisieux A, Mighell AJ, Robinson PA, Inglehearn CF, Isaacs JD, Markham AF (2003) Real-time PCR based on SYBR-Green I fluorescence: an alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions. BMC Biotechnol 3:18
23. Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, Romani N, Schuler G (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 223:77-92
24. Anderson CF, Oukka M, Kuchroo VJ, Sacks D (2007) CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med 204:285-297
25. Jankovic D, Kullberg MC, Feng CG, Goldszmid RS, Collazo CM, Wilson M, Wynn TA, Kamanaka M, Flavell RA, Sher A (2007) Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med 204:273-283
26. Misslitz AC, Bonhagen K, Harbecke D, Lippuner C, Kamradt T, Aebischer T (2004) Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection. Eur J Immunol 34:715-725
27. Bazzoni F, Beutler B (1996) The tumour necrosis factor ligand and receptor families. N Engl J Med 334:1717-1725
28. Neumann B, Machleidt T, Lifka A, Pfeffer K, Vestweber D, Mak TW, Holzmann B, Krönke M (1996) Crucial Role of 55-kilodalton TNF receptor in TNF-induced adhesion molecule expression and leukocyte organ infiltration. J Immunol 156:1587-1593
29. Ngo VN, Körner H, Gunn MD, Schmidt KN, Riminton DS, Cooper MD, Browning JL, Sedgwick JD, Cyster JG (1999) Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J Exp Med 189:403-412
30. Janatpour MJ, Hudak S, Sathe M, Sedgwick JD, McEvoy LM (2001) Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment. J Exp Med 194:1375-1384
31. von Stebut E, Metz M, Milon G, Knop J, Maurer M (2003) Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha /beta released from neutrophils recruited by mast cell-derived TNFalpha. Blood 101:210-215
32. Steinman RM, Pack M, Inaba K (1997) Dendritic cells in the T-cell areas of lymphoid organs. Immunol Rev 156:25-37
33. Ritter U, Korner H (2002) Divergent expression of inflammatory dermal chemokines in cutaneous leishmaniasis. Parasite Immunol 24:295-301
34. Ritter U, and Osterloh A (2006) A new view on cutaneous dendritic cell subsets in experimental leishmaniasis. Med Microbiol Immunol (Berl)