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We noted that the bromides darkened after about half an hour from recovery. It is however known that (halomethyl) phenols are chemically unstable and irritant compounds. Chauhan, M. S.; Dean, F. M.; McDonald, S.; Robinson, M. S. J. Chem. Soc., Perkin Trans. 1 1973, 35, 9-363.
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72
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0033063092
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4 in THF according to literature in 80% yield. However, the regenerated resin is less efficient than the original and the yields are lowered. Sieber, F.; Wentworth Jr., P.; Toker, J. D.; Wentworth, A. D.; Metz, W. A.; Reed, N. N.; Janda, K. D. J. Org. Chem. 1999, 64, 5188-5192.
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4 in THF according to literature in 80% yield. However, the regenerated resin is less efficient than the original and the yields are lowered. Sieber, F.; Wentworth Jr., P.; Toker, J. D.; Wentworth, A. D.; Metz, W. A.; Reed, N. N.; Janda, K. D. J. Org. Chem. 1999, 64, 5188-5192.
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Carpino, L. A.; Beyermann, M.; Wenschub, H.; Bienert, M. Acc. Chem. Res. 1996, 29, 268-274.
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