메뉴 건너뛰기




Volumn 14, Issue 16, 2008, Pages 1620-1624

Cytokine transport across the injured blood-spinal cord barrier

Author keywords

Blood brain barrier; Cytokines; LIF; Neurotrophins; Spinal cord injury; TNF

Indexed keywords

CYTOKINE; INTERLEUKIN 15; LEUKEMIA INHIBITORY FACTOR; LEUKEMIA INHIBITORY FACTOR RECEPTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 48949117574     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161208784705450     Document Type: Review
Times cited : (43)

References (53)
  • 1
    • 0014757558 scopus 로고
    • The blood-brain barrier to proteins under normal and pathological conditions
    • Brightman MW, Klatzo I, Olsson Y, Reese TS. The blood-brain barrier to proteins under normal and pathological conditions. J Neurol Sci 1970; 10: 215-39.
    • (1970) J Neurol Sci , vol.10 , pp. 215-239
    • Brightman, M.W.1    Klatzo, I.2    Olsson, Y.3    Reese, T.S.4
  • 3
    • 0036562894 scopus 로고    scopus 로고
    • In vivo assessment of blood-spinal cord barrier permeability: Serial dynamic contrast enhanced MRI of spinal cord injury
    • Bilgen M, Dogan B, Narayana PA. In vivo assessment of blood-spinal cord barrier permeability: Serial dynamic contrast enhanced MRI of spinal cord injury. Magn Reson Imaging 2002; 20: 337-41.
    • (2002) Magn Reson Imaging , vol.20 , pp. 337-341
    • Bilgen, M.1    Dogan, B.2    Narayana, P.A.3
  • 4
    • 0024515595 scopus 로고
    • Distribution and time course of protein extravasation in the rat spinal cord after contusive injury
    • Noble LJ, Wrathall JR. Distribution and time course of protein extravasation in the rat spinal cord after contusive injury. Brain Res 1989; 482: 57-66.
    • (1989) Brain Res , vol.482 , pp. 57-66
    • Noble, L.J.1    Wrathall, J.R.2
  • 5
    • 17844370509 scopus 로고    scopus 로고
    • Neural plasticity after spinal cord injury
    • Ding Y, Kastin AJ, Pan W. Neural plasticity after spinal cord injury. Curr Pharm Des 2005; 11: 1441-50.
    • (2005) Curr Pharm Des , vol.11 , pp. 1441-1450
    • Ding, Y.1    Kastin, A.J.2    Pan, W.3
  • 6
    • 16244395514 scopus 로고    scopus 로고
    • Strategies to create a regenerating environment for the injured spinal cord
    • Xiang S, Pan W, Kastin AJ. Strategies to create a regenerating environment for the injured spinal cord. Curr Pharm Des 2005; 11: 1267-77.
    • (2005) Curr Pharm Des , vol.11 , pp. 1267-1277
    • Xiang, S.1    Pan, W.2    Kastin, A.J.3
  • 7
    • 16244419079 scopus 로고    scopus 로고
    • Targeting neurite growth inhibitors to induce CNS regeneration
    • Kastin AJ, Pan W. Targeting neurite growth inhibitors to induce CNS regeneration. Curr Pharm Des 2005; 11: 1247-53.
    • (2005) Curr Pharm Des , vol.11 , pp. 1247-1253
    • Kastin, A.J.1    Pan, W.2
  • 8
    • 0030249926 scopus 로고    scopus 로고
    • Production of tumor necrosis factor in spinal cord following traumatic injury in rats
    • Wang CX, Nuttin B, Heremans H, Dom R, Gybels J. Production of tumor necrosis factor in spinal cord following traumatic injury in rats. J Neuroimmunol 1996; 69: 151-6.
    • (1996) J Neuroimmunol , vol.69 , pp. 151-156
    • Wang, C.X.1    Nuttin, B.2    Heremans, H.3    Dom, R.4    Gybels, J.5
  • 9
    • 0027517309 scopus 로고
    • Murine tumor necrosis factor alpha is transported from blood to brain in the mouse
    • Gutierrez EG, Banks WA, Kastin AJ. Murine tumor necrosis factor alpha is transported from blood to brain in the mouse. J Neuroimmunol 1993; 47: 169-76.
    • (1993) J Neuroimmunol , vol.47 , pp. 169-176
    • Gutierrez, E.G.1    Banks, W.A.2    Kastin, A.J.3
  • 10
    • 0030992694 scopus 로고    scopus 로고
    • Permeability of the blood-brain and blood-spinal cord barriers to interferons
    • Pan W, Banks WA, Kastin AJ. Permeability of the blood-brain and blood-spinal cord barriers to interferons. J Neuroimmunol 1997; 76: 105-11.
    • (1997) J Neuroimmunol , vol.76 , pp. 105-111
    • Pan, W.1    Banks, W.A.2    Kastin, A.J.3
  • 11
    • 0036009924 scopus 로고    scopus 로고
    • TNFα transport across the blood-brain barrier is abolished in receptor knockout mice
    • Pan W, Kastin AJ. TNFα transport across the blood-brain barrier is abolished in receptor knockout mice. Exp Neurol 2002; 174: 193-200.
    • (2002) Exp Neurol , vol.174 , pp. 193-200
    • Pan, W.1    Kastin, A.J.2
  • 12
    • 0242469194 scopus 로고    scopus 로고
    • Upregulation of p55 and p75 receptors mediating TNF alpha transport across the injured blood-spinal cord barrier
    • Pan W, Csernus B, Kastin AJ. Upregulation of p55 and p75 receptors mediating TNF alpha transport across the injured blood-spinal cord barrier. J Mol Neurosci 2003; 21: 173-84.
    • (2003) J Mol Neurosci , vol.21 , pp. 173-184
    • Pan, W.1    Csernus, B.2    Kastin, A.J.3
  • 16
    • 0025754376 scopus 로고
    • Tumor necrosis factor facilitates regeneration of injured central nervous system axons
    • Schwartz M, Solomon A, Lavie V, Ben-Bassat S, Belkin M, Cohen A. Tumor necrosis factor facilitates regeneration of injured central nervous system axons. Brain Res 1991; 545: 334-8.
    • (1991) Brain Res , vol.545 , pp. 334-338
    • Schwartz, M.1    Solomon, A.2    Lavie, V.3    Ben-Bassat, S.4    Belkin, M.5    Cohen, A.6
  • 17
    • 0028567790 scopus 로고
    • Cytokines and cytokine-related substances regulating glial cell response to injury of the central nervous system
    • Schwartz M, Sivron T, Eitan S, Hirschberg DL, Lotan M, Elman-Faber A. Cytokines and cytokine-related substances regulating glial cell response to injury of the central nervous system. Prog Brain Res 1994; 103: 331-41.
    • (1994) Prog Brain Res , vol.103 , pp. 331-341
    • Schwartz, M.1    Sivron, T.2    Eitan, S.3    Hirschberg, D.L.4    Lotan, M.5    Elman-Faber, A.6
  • 18
    • 0028006363 scopus 로고
    • Inflammation after axonal injury has conflicting consequences for recovery of function: Rescue of spared axons impaired but regeneration is supported
    • Hirschberg DL, Yoles E, Belkin M, Schwartz M. Inflammation after axonal injury has conflicting consequences for recovery of function: Rescue of spared axons impaired but regeneration is supported. J Neuroimmunol 1994; 50: 9-16.
    • (1994) J Neuroimmunol , vol.50 , pp. 9-16
    • Hirschberg, D.L.1    Yoles, E.2    Belkin, M.3    Schwartz, M.4
  • 19
    • 0030746939 scopus 로고    scopus 로고
    • Effects of pro-inflammatory cytokines in experimental spinal cord injury
    • Klusman I, Schwab ME. Effects of pro-inflammatory cytokines in experimental spinal cord injury. Brain Res 1997; 762: 173-84.
    • (1997) Brain Res , vol.762 , pp. 173-184
    • Klusman, I.1    Schwab, M.E.2
  • 20
    • 0029852805 scopus 로고    scopus 로고
    • Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat
    • Kim DH, Gutin PH, Noble LJ. Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat. Neuroreport 1996; 7: 2221-5.
    • (1996) Neuroreport , vol.7 , pp. 2221-2225
    • Kim, D.H.1    Gutin, P.H.2    Noble, L.J.3
  • 21
    • 0031214872 scopus 로고    scopus 로고
    • Blood-brain barrier permeability to ebiratide and TNF in acute spinal cord injury
    • Pan W, Banks WA, Kastin AJ. Blood-brain barrier permeability to ebiratide and TNF in acute spinal cord injury. Exp Neurol 1997; 146: 367-73.
    • (1997) Exp Neurol , vol.146 , pp. 367-373
    • Pan, W.1    Banks, W.A.2    Kastin, A.J.3
  • 22
    • 0033135362 scopus 로고    scopus 로고
    • Upreguladon of tumor necrosis factor α transport across the blood-brain barrier after acute compressive spinal cord injury
    • Pan W, Kastin AJ, Bell RL, Olson RD. Upreguladon of tumor necrosis factor α transport across the blood-brain barrier after acute compressive spinal cord injury. J Neurosci 1999; 19: 3649-55.
    • (1999) J Neurosci , vol.19 , pp. 3649-3655
    • Pan, W.1    Kastin, A.J.2    Bell, R.L.3    Olson, R.D.4
  • 23
    • 0034741980 scopus 로고    scopus 로고
    • Increase in TNFα transport after SCI is specific for time, region and type of lesion
    • Pan W, Kastin AJ. Increase in TNFα transport after SCI is specific for time, region and type of lesion. Exp Neurol 2001; 170: 357-63.
    • (2001) Exp Neurol , vol.170 , pp. 357-363
    • Pan, W.1    Kastin, A.J.2
  • 24
    • 0037219053 scopus 로고    scopus 로고
    • Selective increase in TNFα permeation across the blood-spinal cord barrier after SCI
    • Pan W, Zhang L, Liao J, Csernus B, Kastin AJ. Selective increase in TNFα permeation across the blood-spinal cord barrier after SCI. J Neuroimmunol 2003; 134: 111-7.
    • (2003) J Neuroimmunol , vol.134 , pp. 111-117
    • Pan, W.1    Zhang, L.2    Liao, J.3    Csernus, B.4    Kastin, A.J.5
  • 25
    • 0035496978 scopus 로고    scopus 로고
    • Upregulation of the transport system for TNFα at the blood-brain barrier
    • Pan W, Kastin AJ. Upregulation of the transport system for TNFα at the blood-brain barrier. Arch Physiol Biochem 2001; 109: 350-3.
    • (2001) Arch Physiol Biochem , vol.109 , pp. 350-353
    • Pan, W.1    Kastin, A.J.2
  • 26
    • 0036009924 scopus 로고    scopus 로고
    • TNFα transport across the blood-brain barrier is abolished in receptor knockout mice
    • Pan W, Kastin AJ. TNFα transport across the blood-brain barrier is abolished in receptor knockout mice. Exp Neurol 2002; 174: 193-200.
    • (2002) Exp Neurol , vol.174 , pp. 193-200
    • Pan, W.1    Kastin, A.J.2
  • 27
  • 28
    • 45249105985 scopus 로고    scopus 로고
    • Permeation of blood-borne IL15 across the blood-brain barrier and the of effect of LPS
    • PMID No. 18384647, in press
    • Pan W, Hsuchou H, Yu C, Kastin AJ. Permeation of blood-borne IL15 across the blood-brain barrier and the of effect of LPS. J Neurochem (in press). PMID No. 18384647.
    • J Neurochem
    • Pan, W.1    Hsuchou, H.2    Yu, C.3    Kastin, A.J.4
  • 29
    • 0037335691 scopus 로고    scopus 로고
    • Increased hippocampal uptake of tumor necrosis factor α and behavioral changes in mice
    • Pan W, Kastin AJ, Rigai T, McLay RN, Pick CG. Increased hippocampal uptake of tumor necrosis factor α and behavioral changes in mice. Exp Brain Res 2003; 149: 195-9.
    • (2003) Exp Brain Res , vol.149 , pp. 195-199
    • Pan, W.1    Kastin, A.J.2    Rigai, T.3    McLay, R.N.4    Pick, C.G.5
  • 30
    • 32644440951 scopus 로고    scopus 로고
    • Stroke upregulates TNFα transport across the blood-brain barrier
    • Pan W, Ding Y, Yu Y, Ohtaki H, Nakamachi T, Kastin AJ. Stroke upregulates TNFα transport across the blood-brain barrier. Exp Neurol 2006; 198: 222-33.
    • (2006) Exp Neurol , vol.198 , pp. 222-233
    • Pan, W.1    Ding, Y.2    Yu, Y.3    Ohtaki, H.4    Nakamachi, T.5    Kastin, A.J.6
  • 31
    • 0034237420 scopus 로고    scopus 로고
    • Saturable entry of leukemia inhibitory factor from blood to the central nervous system
    • Pan W, Kastin AJ, Brennan JM. Saturable entry of leukemia inhibitory factor from blood to the central nervous system. J Neurochem 2000; 106: 172-80.
    • (2000) J Neurochem , vol.106 , pp. 172-180
    • Pan, W.1    Kastin, A.J.2    Brennan, J.M.3
  • 32
    • 0033582965 scopus 로고    scopus 로고
    • Saturable entry of ciliary neurotrophic factor into brain
    • Pan W, Kastin AJ, Maness LM, Brennan JM. Saturable entry of ciliary neurotrophic factor into brain. Neurosci Lett 1999; 263: 69-71.
    • (1999) Neurosci Lett , vol.263 , pp. 69-71
    • Pan, W.1    Kastin, A.J.2    Maness, L.M.3    Brennan, J.M.4
  • 33
    • 33646103677 scopus 로고    scopus 로고
    • Receptor-mediated transport of LIF across blood-spinal cord barrier is upregulated after spinal cord injury
    • Pan W, Cain CM, Yu Y, Kastin AJ. Receptor-mediated transport of LIF across blood-spinal cord barrier is upregulated after spinal cord injury. J Neuroimmunol 2006; 174: 119-25.
    • (2006) J Neuroimmunol , vol.174 , pp. 119-125
    • Pan, W.1    Cain, C.M.2    Yu, Y.3    Kastin, A.J.4
  • 34
    • 34249909027 scopus 로고    scopus 로고
    • Opposing effects of proteasomes and lysosomes on LIFR: Modulation by TNF
    • Yu C, Kastin AJ, Tu H, Pan W. Opposing effects of proteasomes and lysosomes on LIFR: Modulation by TNF. J Mol Neurosci 2007; 32: 80-9.
    • (2007) J Mol Neurosci , vol.32 , pp. 80-89
    • Yu, C.1    Kastin, A.J.2    Tu, H.3    Pan, W.4
  • 35
    • 34548477171 scopus 로고    scopus 로고
    • TNF reduces LIF endocytosis despite increasing NFkappaB-mediated gp130 expression
    • Yu C, Kastin AJ, Pan W. TNF reduces LIF endocytosis despite increasing NFkappaB-mediated gp130 expression. J Cell Physiol 2007; 213: 161-6.
    • (2007) J Cell Physiol , vol.213 , pp. 161-166
    • Yu, C.1    Kastin, A.J.2    Pan, W.3
  • 36
    • 0034528176 scopus 로고    scopus 로고
    • Activation of urocortin transport into brain by leptin
    • Kastin AJ, Akerstrom V, Pan W. Activation of urocortin transport into brain by leptin. Peptides 2000; 21: 1811-7.
    • (2000) Peptides , vol.21 , pp. 1811-1817
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 38
    • 0037240853 scopus 로고    scopus 로고
    • Feeding peptides interact in several ways with the blood-brain barrier
    • Kastin AJ, Pan W. Feeding peptides interact in several ways with the blood-brain barrier. Curr Pharm Des 2003; 9: 789-94.
    • (2003) Curr Pharm Des , vol.9 , pp. 789-794
    • Kastin, A.J.1    Pan, W.2
  • 39
    • 3142683672 scopus 로고    scopus 로고
    • Modulation of feeding-related peptide/protein signals by the blood-brain barrier
    • Pan W, Akerstrom V, Zhang J, Pejovic V, Kastin AJ. Modulation of feeding-related peptide/protein signals by the blood-brain barrier. J Neurochem 2004; 90: 455-61.
    • (2004) J Neurochem , vol.90 , pp. 455-461
    • Pan, W.1    Akerstrom, V.2    Zhang, J.3    Pejovic, V.4    Kastin, A.J.5
  • 40
    • 34249717231 scopus 로고    scopus 로고
    • Adipokines and the blood-brain barrier
    • Pan W, Kastin AJ. Adipokines and the blood-brain barrier. Peptides 2007; 28: 1317-30.
    • (2007) Peptides , vol.28 , pp. 1317-1330
    • Pan, W.1    Kastin, A.J.2
  • 41
    • 33646103677 scopus 로고    scopus 로고
    • Receptor-mediated transport of LIF across blood-spinal cord barrier is upregulated after spinal cord injury
    • Pan W, Cain C, Yu Y, Kastin AJ. Receptor-mediated transport of LIF across blood-spinal cord barrier is upregulated after spinal cord injury. J Neuroimmunol 2006; 174: 119-25.
    • (2006) J Neuroimmunol , vol.174 , pp. 119-125
    • Pan, W.1    Cain, C.2    Yu, Y.3    Kastin, A.J.4
  • 43
    • 0035756597 scopus 로고    scopus 로고
    • Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: Meaningful controls
    • Kastin AJ, Akerstrom V, Pan W. Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: Meaningful controls. Peptides 2001; 22: 2127-36.
    • (2001) Peptides , vol.22 , pp. 2127-2136
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 45
    • 0035816419 scopus 로고    scopus 로고
    • Bradykinin antagonist decreases early disruption of the blood-spinal cord barrier after spinal cord injury in mice
    • Pan W, Kastin AJ, Gera L, Stewart JM. Bradykinin antagonist decreases early disruption of the blood-spinal cord barrier after spinal cord injury in mice. Neurosci Lett 2001; 307: 25-8.
    • (2001) Neurosci Lett , vol.307 , pp. 25-28
    • Pan, W.1    Kastin, A.J.2    Gera, L.3    Stewart, J.M.4
  • 46
    • 0032080317 scopus 로고    scopus 로고
    • Effect of spinal cord injury on the permeability of the blood-brain and blood-spinal cord barriers to the neurotrophin PACAP
    • Banks WA, Kastin AJ, Arimura A. Effect of spinal cord injury on the permeability of the blood-brain and blood-spinal cord barriers to the neurotrophin PACAP. Exp Neurol 1998; 151: 116-23.
    • (1998) Exp Neurol , vol.151 , pp. 116-123
    • Banks, W.A.1    Kastin, A.J.2    Arimura, A.3
  • 47
    • 0028168503 scopus 로고
    • Blood-borne interleukin-1α is transported across the endothelial blood-spinal cord barrier of mice
    • Banks WA, Kastin AJ, Ehrensing Cg Blood-borne interleukin-1α is transported across the endothelial blood-spinal cord barrier of mice. J Physiol 1994; 479(Pt 2): 257-64.
    • (1994) J Physiol , vol.479 , Issue.PART 2 , pp. 257-264
    • Banks, W.A.1    Kastin, A.J.2    Ehrensing, C.3
  • 48
    • 0030814828 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor crosses the blood-brain and blood-spinal cord barriers
    • McLay RN, Kimura M, Banks WA, Kastin AJ. Granulocyte-macrophage colony-stimulating factor crosses the blood-brain and blood-spinal cord barriers. Brain 1997; 120: 2083-91.
    • (1997) Brain , vol.120 , pp. 2083-2091
    • McLay, R.N.1    Kimura, M.2    Banks, W.A.3    Kastin, A.J.4
  • 49
    • 1042289645 scopus 로고    scopus 로고
    • Neuregulin-1-beta1 enters brain and spinal cord by receptor-mediated transport
    • Kastin AJ, Akerstrom V, Pan W. Neuregulin-1-beta1 enters brain and spinal cord by receptor-mediated transport. J Neurochem 2004; 88: 965-70.
    • (2004) J Neurochem , vol.88 , pp. 965-970
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 50
    • 0032579839 scopus 로고    scopus 로고
    • Permeability of the blood-brain/spinal cord barrier to neurotrophins
    • Pan W, Banks WA, Kastin AJ. Permeability of the blood-brain/spinal cord barrier to neurotrophins. Brain Res 1998; 788: 87-94.
    • (1998) Brain Res , vol.788 , pp. 87-94
    • Pan, W.1    Banks, W.A.2    Kastin, A.J.3
  • 51
    • 33947602024 scopus 로고    scopus 로고
    • Towards the development of tumor necrosis factor (TNF) sensitizers: Making TNF work against cancer
    • Mocellin S, Pilati P, Nitti D. Towards the development of tumor necrosis factor (TNF) sensitizers: Making TNF work against cancer. Curr Pharm Des 2007; 13(5): 537-51.
    • (2007) Curr Pharm Des , vol.13 , Issue.5 , pp. 537-551
    • Mocellin, S.1    Pilati, P.2    Nitti, D.3
  • 52
    • 34347357759 scopus 로고    scopus 로고
    • Neurotrophic factors in combination: A possible new therapeutic strategy to influence pathophysiology of spinal cord injury and repair mechanisms
    • Sharma HS. Neurotrophic factors in combination: A possible new therapeutic strategy to influence pathophysiology of spinal cord injury and repair mechanisms. Curr Pharm Des 2007; 13(18): 1841-74.
    • (2007) Curr Pharm Des , vol.13 , Issue.18 , pp. 1841-1874
    • Sharma, H.S.1
  • 53
    • 34347364696 scopus 로고    scopus 로고
    • Drugs of abuse-induced hyperthermia, blood-brain barrier dysfunction and neurotoxicity: Neuroprotective effects of a new antioxidant compound H-290/51
    • Sharma HS, Sjoquist PO, Ali SF. Drugs of abuse-induced hyperthermia, blood-brain barrier dysfunction and neurotoxicity: Neuroprotective effects of a new antioxidant compound H-290/51. Curr Pharm Des 2007; 13(18): 1903-23.
    • (2007) Curr Pharm Des , vol.13 , Issue.18 , pp. 1903-1923
    • Sharma, H.S.1    Sjoquist, P.O.2    Ali, S.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.