Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) Suppresses TKR-Growth Factor Signaling Independent of Metalloproteinase Inhibition

Journal of Biological Chemistry

Volumn 276, Issue 5, 2001, Pages 3203-3214

  Hoegy, Susan E ^c   Oh, Hae Ryong ^c   Corcoran, Marta L ^a   Stetler Stevenson, William G ^b  

^a IGEN Inc   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ACTIVATION; CHEMICAL BONDS; COMPLEXATION; CYTOLOGY; DISSOCIATION; ENZYME INHIBITION; IMMUNOLOGY; METALLORGANIC POLYMERS; TISSUE;

MITOGENESIS;

ENZYMES;

9 (TETRAHYDRO 2 FURYL)ADENINE; ADENYLATE CYCLASE; BASIC FIBROBLAST GROWTH FACTOR; CYCLIC AMP; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; IODINE 125; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE PHOSPHATASE; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR ALPHA; TYROSINE KINASE RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GRB2 PROTEIN, HUMAN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INTERSTITIAL COLLAGENASE; PROTEIN; PROTEIN TYROSINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ASSAY; ENZYME INHIBITION; ESCHERICHIA COLI; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL CULTURE; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ESCHERICHIA COLI;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENYLATE CYCLASE; CELL DIVISION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; GRB2 ADAPTOR PROTEIN; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASES; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TUMOR CELLS, CULTURED;

EID: 0035793638     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008157200     Document Type: Article

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