Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution

Journal of Molecular Biology

Volumn 284, Issue 4, 1998, Pages 1133-1140

  Tuuttila, Ari ^a   Morgunova, Ekaterina ^a   Bergmann, Ulrich ^a   Lindqvist, Ylva ^a   Maskos, Klaus ^b   Fernandez Catalan, Carlos ^b   Bode, Wolfram ^b   Tryggvason, Karl ^a   Schneider, Gunter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Collagenases; Metalloproteinases; Protein crystallography; Proteinase inhibitor; TIMP

Indexed keywords

DNA BINDING PROTEIN; OLIGONUCLEOTIDE; OLIGOSACCHARIDE; TISSUE INHIBITOR OF METALLOPROTEINASE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

BOVINAE;

EID: 0032509104     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2223     Document Type: Article

References (35)

1. Bacon D. J., Anderson W. F. A fast algorithm for rendering space-filling molecule pictures. J. Mol. Graph. 6:1988;219-220.
2. Banyai L., Tordai H., Patthy L. The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A). Biochem. J. 298:1994;403-407.
3. Bigg H. F., Shi Y. E., Liu Y. L. E., Steffensen B., Overall C. M. Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP4) to the COOH-terminal hemopexin-like domain of human gelatinase a-TIMP-4 binds progelatinase a and the COOH-terminal domain in a similar manner to TIMP-2. J. Biol. Chem. 272:1997;15496-15500.
4. Birkedal-Hansen H. Proteolytic remodeling of extracellular matrix. Curr. Opin. Cell Biol. 7:1995;728-735.
5. Bochkarev A., Pfuetzner R. A., Edwards A. M., Frappier L. Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA. Nature. 385:1997;176-181.
6. Brunger A. T., Kuriyan J., Karplus M. Crystallographic R factor refinement by molecular dynamics. Science. 235:1987;458-460.
7. Butler G. S., Butler M. J., Atkinson S. J., Will H., Tamura T., van Westrum S. S., Crabbe T., Clements J., d'Ortho M. P., Murphy G. The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J. Biol. Chem. 273:1998;871-880.
8. Fernandez-Catalan C., Bode W., Huber R., Turk D., Calvete J. J., Lichte A., Tschesche H., Maskos K. Crystal structure of the complex formed by the membrane type 1 matrix metalloproteinase with the tissue inhibitor of metallo proteinases-2, the soluble progelatinase A receptor. EMBO J. 17:1998;5238-5278.
9. Gomez D. E., Alonso D. F., Yoshiji H., Thorgeirsson U. P. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Europ. J. Cell Biol. 74:1997;111-122.
10. Gomis-Ruth F. X., Maskos K., Betz M., Bergner A., Huber R., Suzuki K., Yoshida N., Nagase H., Brew K., Bourenkov G. P., Bartunik H., Bode W. Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature. 389:1997;77-81.
11. Hayakawa T., Yamashita K., Ohuchi E., Shinagawa A. Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). J. Cell Sci. 107:1994;2373-2379.
12. Jones T. A., Zou J.-Y., Cowan S. W., Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallog. sect. A. 47:1991;110-119.
13. Kraulis P. J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallog. 24:1991;946-950.
14. Laskowski R. A., MacArthur M. W., Moss D. S., Thornton J. M. PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Crystallog. 26:1993;283-291.
15. Liotta L. A., Stetler-Stevenson W. G. Metalloproteinases and cancer invasion. Semin. Cancer Biol. 1:1990;99-106.
16. Lu G. A WWW service system for automatic comparison of protein structures. Protein Data Bank Quart. Newsletter. 78:1996;10-11.
17. Merritt E. A., Murphy M. E. P. Raster3D Version 2.0: a program for photorealistic molecular graphics. Acta Crystallog. sect. D. 50:1994;869-873.
18. Miyazaki K., Funahashi K., Numata Y., Koshikawa N., Akaogi K., Kikkawa Y., Yasumitsu H., Umeda M. Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein. J. Biol. Chem. 268:1993;14387-14393.
19. Murphy G., Houbrechts A., Cockett M. I., Williamson R. A., O'Shea M., Docherty A. J. The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity. Biochemistry. 30:1991;8097-8102.
20. Murshudov G. N., Vagin A. A., Dodson E. J. Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallog. sect. D. 53:1997;240-255.
21. Murzin A. G. OB(oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences. EMBO J. 12:1993;861-867.
22. Navaza J. AMoRe: an automated package for molecular replacement. Acta Crystallog. sect. A. 50:1994;157-163.
23. Olson M. W., Gervasi D. C., Mobashery S., Fridman R. Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (Timp)-1 and Timp-2. J. Biol. Chem. 272:1997;29975-29983.
24. Otwinowski Z., Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:1997;307-326.
25. Pyke C., Ralfkiaer E., Huhtala P., Hurskainen T., Dano K., Tryggvason K. Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization. Cancer Res. 52:1992;1336-1341.
26. Pyke C., Ralfkiaer E., Tryggvason K., Dano K. Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer. Am. J. Pathol. 142:1993;359-365.
27. Reponen P., Sahlberg C., Huhtala P., Hurskainen T., Thesleff I., Tryggvason K. Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development. J. Biol. Chem. 267:1992;7856-7862.
28. Stetler-Stevenson W. G., Bersch N., Golde D. W. Tissue inhibitor of metalloproteinase-2 (TIMP-2) has erythroid-potentiating activity. FEBS Letters. 296:1992;231-234.
29. Stetler-Stevenson W. G., Liotta L. A., Kleiner D. E. Jr. Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. FASEB J. 7:1993;1434-1441.
30. Van Wart H. E., Birkedal-Hansen H. The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc. Natl Acad. Sci. USA. 87:1990;5578-5582.
31. Wilhelm S. M., Collier I. E., Marmer B. L., Eisen A. Z., Grant G. A., Goldberg G. I. SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J. Biol. Chem. 264:1989;17213-17221.
32. Willenbrock F., Crabbe T., Slocombe P. M., Sutton C. W., Docherty A. J., Cockett M. I., O'Shea M., Brocklehurst K., Phillips I. R., Murphy G. The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A. Biochemistry. 32:1993;4330-4337.
33. Williamson R. A., Martorell G., Carr M. D., Murphy G., Docherty A. J., Freedman R. B., Feeney J. Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family. Biochemistry. 33:1994;11745-11759.
34. Williamson R. A., Carr M. D., Frenkiel T. A., Feeney J., Freedman R. B. Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation. Biochemistry. 36:1997;13882-13889.
35. Zucker S., Drews M., Conner C., Foda H. D., Declerck Y. A., Langley K. E., Bahou W. F., Docherty A. J. P., Cao J. Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1 matrix metalloproteinase 1 (MT1-MMP). J. Biol. Chem. 273:1998;1216-1222.