Metal-free artificial nucleases based on simple oxime and hydroxylamine scaffolds

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 16, 2008, Pages 4499-4502

  Fernandes, Luciano ^a   Fischer, Franciele L ^a   Ribeiro, Carolina W ^a   Silveira, Gustavo P ^a   Sá, Marcus M ^a   Nome, Faruk ^a   Terenzi, Hernán ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

DNA cleavage; Hydroxylamines; Metal free nuclease; Oximes

Indexed keywords

DNA; HYDROXYLAMINE; NUCLEASE; NUCLEIC ACID; OXIME;

ARTICLE; BIOTECHNOLOGY; COVALENT BOND; DNA DEGRADATION; DNA SEQUENCE; DNA STRUCTURE; PROTEIN HYDROLYSIS; STRUCTURE ANALYSIS;

CHEMISTRY; DEOXYRIBONUCLEASES; DISTAMYCINS; DNA; DRUG DESIGN; GLYCEROL; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; HYDROXYLAMINES; KINETICS; METALS; NUCLEIC ACID CONFORMATION; NUCLEIC ACIDS; OXIMES; SOLVENTS;

EID: 48649102794     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.07.052     Document Type: Article

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