Lanthanide-mediated DNA hydrolysis

Current Opinion in Chemical Biology

Volumn 5, Issue 2, 2001, Pages 201-208

  Franklin, Sonya J ^a  

^a University of Iowa ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; AZACROWN; BIOPOLYMER; BIS(4 NITROPHENYL) PHOSPHATE; CARBOXYLIC ACID DERIVATIVE; CERIUM; CROWN ETHER DERIVATIVE; DEXTRAN; DNA; HYDROXAMIC ACID; LANTHANIDE; LANTHANUM; LIGAND; MACROCYCLIC COMPOUND; METAL COMPLEX; NUCLEASE; OLIGONUCLEOTIDE; PEPTIDE; POLYAMINOCARBOXYLATE DERIVATIVE; PROTEIN; SCHIFF BASE; UNCLASSIFIED DRUG;

CATALYSIS; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DNA CLEAVAGE; ENZYME ACTIVITY; HYDROLYSIS; IONIC STRENGTH; MICELLE; MOLECULAR SIZE; NUCLEAR MAGNETIC RESONANCE IMAGING; REVIEW; STRUCTURE ANALYSIS;

EID: 0035313441     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00191-5     Document Type: Review

References (48)

1. Progress toward synthetic enzymes for phosphoester hydrolysis
2. Bioinorganic models for the catalytic cooperation of metal ions and functional groups in nuclease and peptidase enzymes
3. DNA hydrolysis by inorganic catalysts
4. Artificial dinuclear phosphoesterases
5. Toward the development of metal-based synthetic nucleases and peptidases: A rationale and progress report in applying the principles of coordination chemistry
6. Research progresses of artificial nucleic acid cleavage agents
7. 2+ ion in the presence of bisintercalator containing penta(ethylene glycol) connector chain
8. Catalysis of DNA cleavage by lanthanide complexes with nucleophilic or intercalating ligands and their kinetic characterization
9. Ligand and cosubstrate effects on the hydrolysis of phosphate esters and DNA with lanthanoids
10. Unusual catalyst concentration effects in the hydrolysis of phenyl phosphate esters and of DNA: A systematic investigation of the lanthanide series
11. Recent studies of nucleophilic, general-acid, and metal ion catalysis of phosphate diester hydrolysis
12. Hydrolysis of DNA and RNA by lanthanide ions: Mechanistic studies leading to new applications
13. Co(III) complex promoted hydrolysis of phosphate diesters: Comparison in reactivity of rigid cis-diaquotetraazacobalt(III) complexes
14. Kinetics of phosphodiester hydrolysis by lanthanide ions in weakly basic solutions
15. Gadolinium (III) chelates as MRI contrast agents: Structure, dynamics, and applications
16. Remarkable acceleration of dimethyl phosphate hydrolysis by ceric cations
17. Extended X-ray absorption fine structure study on the cerium(IV)-induced DNA hydrolysis: Implication to the roles of 4f orbitals in the catalysis
18. Efficient catalytic cleavage of RNA by lanthanide(III) macrocyclic complexes: Toward synthetic nucleases for in vivo applications
19. Lanthanide binuclear macrocyclic complexes as synthetic enzymes for the cleavage of DNA
20. Binuclear lanthanide complexes as catalysts for the hydrolysis of double-stranded DNA
21. Phosphate diester hydrolysis by mono- and dinuclear lanthanum complexes with an unusual third-order dependence
22. Binuclear lanthanide complexes as catalysts for the hydrolysis of bis(p-nitrophenyl)-phosphate and double-stranded DNA
23. Carboxylic groups as cofactors in the lanthanide-catalyzed hydrolysis of phosphate esters. Stabilities of europium(III) complexes with aza-benzo-15-crown-5 ether derivatives and their catalytic activity vs bis(p-nitrophenyl)phosphate and DNA
24. A combined parallel synthesis and screening of macrocyclic lanthanide complexes for the cleavage of phospho di- and triesters and double-stranded DNA
25. Hydrolysis of oligonucleotides by homogeneous Ce(IV)/EDTA complex
26. Double-strand DNA hydrolysis by dilanthanide complexes
27. Effect of mixed pendent groups on the solution and catalytic properties of europium(III) macrocyclic complexes: Bifunctional and monfunctional amide and alcohol pendents in septadentate or octadentate ligands
28. 3+ complex of a novel functionalized octadentate ligand
29. 3+
30. Oligonucleotide conjugates of Eu(III) tetraazamacrocycles with pendent alcohol and amide groups promote sequence-specific RNA cleavage
31. Characterization of lanthanide-mediated DNA cleavage by intercalator-linked hydroxamic acids: Comparison with transition systems
32. Sequence specificity of DNA cleavage by bisnetrosin-linked hydroxamic acid-metal complexes: Highly specific cleavage by ferrous complexes
33. Structure and phosphodiesterase activity of Bis-Tris coordinated lanthanide(III) complexes
34. Cerium(IV)/lanthanide(III)/dextran ternary solutions for efficient and homogeneous DNA hydrolysis
35. Homogeneous DNA hydrolysis by cerium(IV)/lanthanide(III)/dextan ternary complexes
36. Remarkably rapid cleavage of a model phosphodiester by complexed ceric ions in aqueous micellar solutions
37. Lanthanide ion-mediated hydrolysis of DNA on phosphate bilayer membrane
38. Inorganic mimics of ribonucleases and ribozymes: From random cleavage to sequence-specific chemistry to catalytic antisense drugs
39. Sequence-specific and hydrolytic scission of DNA and RNA by lanthanide complex-oligoDNA hybrids
40. Ni(II) Xaa-Xaa-His metallopeptide DNA/RNA interactions
41. In vivo and in vitro iron-replaced zinc finger generates free radicals and causes DNA damage
42. Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain
43. Design of a synthetic nuclease: DNA hydrolysis by a zinc-binding peptide tethered to a rhodium intercalator
44. Chimeric HTH motifs based on EF-hands
45. Engrailed (Gln50(Lys) homeodomain-DNA complex at 1.9 A resolution: Structural basis for enhanced affinity and altered specificity
46. Structure of Paramecium tetraurelia calmodulin at 1.8 angstroms resolution
47. De novo nucleases based on HTH and EF-hand chimeras