메뉴 건너뛰기




Volumn 38, Issue 3, 2003, Pages 692-702

Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; 8 (2 OCTYLCYCLOPROPYL)OCTANOIC ACID 2 (2 METHOXYETHOXY)ETHYL ESTER; ALCOHOL; CARRIER PROTEIN; CHOLESTEROL; COMPLEMENTARY RNA; GLUTAMIC ACID; GLUTATHIONE; MESSENGER RNA; PHENYLSUCCINATE; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0041822088     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50351     Document Type: Article
Times cited : (127)

References (36)
  • 1
    • 0026387907 scopus 로고
    • Glutathione metabolism and its role in hepatoxicity
    • Delve L, Kaplowitz N. Glutathione metabolism and its role in hepatoxicity. Pharmacol Ther 1991;52:287-305.
    • (1991) Pharmacol Ther , vol.52 , pp. 287-305
    • Delve, L.1    Kaplowitz, N.2
  • 2
    • 0001547757 scopus 로고
    • Origin and turnover of mitochondrial glutathione
    • Griffith OW, Meister A. Origin and turnover of mitochondrial glutathione. Proc Natl Acad Sci U S A 1985;82:4668-2372.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 4668-2372
    • Griffith, O.W.1    Meister, A.2
  • 3
    • 0028229899 scopus 로고
    • Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes
    • García-Ruiz C, Morales A, Colell A, Ballesta A, Rodés J, Kaplowitz N, Fernández-Checa JC. Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes. J Clin Invest 1994;94:193-201.
    • (1994) J Clin Invest , vol.94 , pp. 193-201
    • García-Ruiz, C.1    Morales, A.2    Colell, A.3    Ballesta, A.4    Rodés, J.5    Kaplowitz, N.6    Fernández-Checa, J.C.7
  • 5
    • 0037427413 scopus 로고    scopus 로고
    • Redox regulation and signaling lipids in mitochondrial apoptosis
    • Fernández-Checa JC. Redox regulation and signaling lipids in mitochondrial apoptosis. Biochem Biophys Res Commun 2003;304:471-479.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 471-479
    • Fernández-Checa, J.C.1
  • 6
    • 0036673665 scopus 로고    scopus 로고
    • Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in HL60 cells that overexpress Bcl-2
    • Armstrong JS, Jones DP. Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in HL60 cells that overexpress Bcl-2. FASEB J 2002;16:1263-1265.
    • (2002) FASEB J , vol.16 , pp. 1263-1265
    • Armstrong, J.S.1    Jones, D.P.2
  • 7
    • 0036827706 scopus 로고    scopus 로고
    • Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter
    • Lash LH, Putt DA, Matherly PH. Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter. J Pharmacol Exp Ther 2002;303:476-486.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 476-486
    • Lash, L.H.1    Putt, D.A.2    Matherly, P.H.3
  • 8
    • 0035029170 scopus 로고    scopus 로고
    • Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice
    • Haouzi D, Lekehal M, Tinel M, Vadrot V, Caussanel P, Letteron P, Moreau A, et al. Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice. HEPATOLOGY 2001;33:1181-1188.
    • (2001) Hepatology , vol.33 , pp. 1181-1188
    • Haouzi, D.1    Lekehal, M.2    Tinel, M.3    Vadrot, V.4    Caussanel, P.5    Letteron, P.6    Moreau, A.7
  • 10
    • 0037370152 scopus 로고    scopus 로고
    • Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress
    • Lluis JM, Colell A, García-Ruiz C, Kaplowitz N, Fernández-Checa JC. Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress. Gastroenterology 2003;124:708-724.
    • (2003) Gastroenterology , vol.124 , pp. 708-724
    • Lluis, J.M.1    Colell, A.2    García-Ruiz, C.3    Kaplowitz, N.4    Fernández-Checa, J.C.5
  • 11
    • 0025049139 scopus 로고
    • High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function
    • Martensson J, Lai JC, Meister A. High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function. Proc Natl Acad Sci U S A 1990;87:7185-7189.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 7185-7189
    • Martensson, J.1    Lai, J.C.2    Meister, A.3
  • 12
    • 0031836944 scopus 로고    scopus 로고
    • Evidence for mitochondrial uptake of glutathione by dicarboxylate and 2-oxoglutarte carriers
    • Chen Z, Lash LH. Evidence for mitochondrial uptake of glutathione by dicarboxylate and 2-oxoglutarte carriers. J Pharmacol Exp Ther 1998;285:608-618.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 608-618
    • Chen, Z.1    Lash, L.H.2
  • 13
    • 0033963540 scopus 로고    scopus 로고
    • Enrichment and functional reconstitution of glutathione transport activity from rabbit kidney mitochondria: Further evidence for the role of the dicarboxylate and 2-oxoglutarate carriers in mitochondrial glutathione transport
    • Chen Z, Putt DA, Lash LH. Enrichment and functional reconstitution of glutathione transport activity from rabbit kidney mitochondria: further evidence for the role of the dicarboxylate and 2-oxoglutarate carriers in mitochondrial glutathione transport. Arch Biochem Biophys 2000;373:193-202.
    • (2000) Arch Biochem Biophys , vol.373 , pp. 193-202
    • Chen, Z.1    Putt, D.A.2    Lash, L.H.3
  • 14
    • 0024604102 scopus 로고
    • Effect of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration
    • Fernández-Checa JC, Ookhtens M, Kaplowitz N. Effect of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration. J Clin Invest 1989;83:1247-1252.
    • (1989) J Clin Invest , vol.83 , pp. 1247-1252
    • Fernández-Checa, J.C.1    Ookhtens, M.2    Kaplowitz, N.3
  • 15
    • 0031789130 scopus 로고    scopus 로고
    • Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
    • Colell A, García-Ruiz C, Miranda M, Ardite E, Mari M, Morales A, Corrales F, et al. Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor. Gastroenterology 1998;115:1541-1551.
    • (1998) Gastroenterology , vol.115 , pp. 1541-1551
    • Colell, A.1    García-Ruiz, C.2    Miranda, M.3    Ardite, E.4    Mari, M.5    Morales, A.6    Corrales, F.7
  • 17
    • 0036891947 scopus 로고    scopus 로고
    • Effects of ethanol dose and ethanol withdrawal on rat liver mitochondrial glutathione: Implication of potentiated acetaminophen toxicity in alcoholics
    • Zhao P, Slartery JT. Effects of ethanol dose and ethanol withdrawal on rat liver mitochondrial glutathione: implication of potentiated acetaminophen toxicity in alcoholics. Drug Metab Dispos 2002;30:1413-1417.
    • (2002) Drug Metab Dispos , vol.30 , pp. 1413-1417
    • Zhao, P.1    Slartery, J.T.2
  • 18
    • 0036322172 scopus 로고    scopus 로고
    • Selective mitochondrial glurathione depletion by ethanol enhances acetaminophen toxicity in rat liver
    • Zhao P, Kalhorn TF, Slattery JT. Selective mitochondrial glurathione depletion by ethanol enhances acetaminophen toxicity in rat liver. HEPATOLOGY 2002;36:326-335.
    • (2002) Hepatology , vol.36 , pp. 326-335
    • Zhao, P.1    Kalhorn, T.F.2    Slattery, J.T.3
  • 19
    • 0030819482 scopus 로고    scopus 로고
    • Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-fed treated rats: Effect of membrane physical properties and S-adenosyl-1-methionine
    • Colell A, García-Ruiz C, Morales A, Ballesta A, Ookhtens M, Rodés J, Kaplowitz N, et al. Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-fed treated rats: effect of membrane physical properties and S-adenosyl-1-methionine. HEPATOLOGY 1997;26:699-708.
    • (1997) Hepatology , vol.26 , pp. 699-708
    • Colell, A.1    García-Ruiz, C.2    Morales, A.3    Ballesta, A.4    Ookhtens, M.5    Rodés, J.6    Kaplowitz, N.7
  • 20
    • 0029052049 scopus 로고
    • Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione
    • García-Ruiz C, Morales A, Colell A, Rodés J, Yi JR, Kaplowitz N, Fernández-Checa JC. Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. J Biol Chem 1995;270:15946-15949.
    • (1995) J Biol Chem , vol.270 , pp. 15946-15949
    • García-Ruiz, C.1    Morales, A.2    Colell, A.3    Rodés, J.4    Yi, J.R.5    Kaplowitz, N.6    Fernández-Checa, J.C.7
  • 21
    • 0028019746 scopus 로고
    • Cell-free apoptosis in Xenopus extracts: Inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria
    • Newmeyer D, Farchson D, Reed JC. Cell-free apoptosis in Xenopus extracts: inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 1994;79:353-364.
    • (1994) Cell , vol.79 , pp. 353-364
    • Newmeyer, D.1    Farchson, D.2    Reed, J.C.3
  • 22
    • 0025697055 scopus 로고
    • Sequence of the bovine 2-oxoglutarate/malate carrier protein: Structural relationship to other mitochondrial transport proteins
    • Runswick MJ, Walker JE, Bisaccia F, Iocobazzi V, Palmieri F. Sequence of the bovine 2-oxoglutarate/malate carrier protein: structural relationship to other mitochondrial transport proteins. Biochemistry 1990;29:11033-11040.
    • (1990) Biochemistry , vol.29 , pp. 11033-11040
    • Runswick, M.J.1    Walker, J.E.2    Bisaccia, F.3    Iocobazzi, V.4    Palmieri, F.5
  • 23
    • 0020483538 scopus 로고
    • A procedure for the rapid preparation of mitochondria from rat liver
    • Reinhart PH, Taylor WM, Bygrave FL. A procedure for the rapid preparation of mitochondria from rat liver. Biochem J 1982;204:731-735.
    • (1982) Biochem J , vol.204 , pp. 731-735
    • Reinhart, P.H.1    Taylor, W.M.2    Bygrave, F.L.3
  • 24
    • 0025979356 scopus 로고
    • Impaired uptake of GSH by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic sudies in vitro and in vivo and susceptibility to oxidants stress
    • Fernández-Checa JC, García-Ruiz C, Ookhtens M, Kaplowitz N. Impaired uptake of GSH by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic sudies in vitro and in vivo and susceptibility to oxidants stress. J Clin Invest 1991;87:397-405.
    • (1991) J Clin Invest , vol.87 , pp. 397-405
    • Fernández-Checa, J.C.1    García-Ruiz, C.2    Ookhtens, M.3    Kaplowitz, N.4
  • 25
    • 0034761961 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione
    • Colell A, Coll O, García-Ruiz C, París R, Tiribelli C, Kaplowitz N, Fernández-Checa JC. Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione. HEPATOLOGY 2001;34 964-971.
    • (2001) Hepatology , vol.34 , pp. 964-971
    • Colell, A.1    Coll, O.2    García-Ruiz, C.3    París, R.4    Tiribelli, C.5    Kaplowitz, N.6    Fernández-Checa, J.C.7
  • 26
    • 0023778239 scopus 로고
    • Cholesterol increase in mitochondria: A new method of cholesterol incorporation
    • Martinez F, Eschegoyen S, Briones R, Cuellar A. Cholesterol increase in mitochondria: a new method of cholesterol incorporation. J Lipid Res 1988;29:1005-1011.
    • (1988) J Lipid Res , vol.29 , pp. 1005-1011
    • Martinez, F.1    Eschegoyen, S.2    Briones, R.3    Cuellar, A.4
  • 27
    • 0015861104 scopus 로고
    • Determination of cholesterol using o-phthaldehyde
    • Rudel LL, Morris MD. Determination of cholesterol using o-phthaldehyde. J Lipid Res 1973;14:364-366.
    • (1973) J Lipid Res , vol.14 , pp. 364-366
    • Rudel, L.L.1    Morris, M.D.2
  • 28
    • 0025322254 scopus 로고
    • Expression of the brown fat mitochondria uncoupling protein in Xenopus oocytes and import into mitochondrial membrane
    • Klaus S, Casteilla L, Bouillaud F, Raimbault S, Ricquier D. Expression of the brown fat mitochondria uncoupling protein in Xenopus oocytes and import into mitochondrial membrane. Biochem Biophys Res Commun 1990;167:784-789.
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 784-789
    • Klaus, S.1    Casteilla, L.2    Bouillaud, F.3    Raimbault, S.4    Ricquier, D.5
  • 29
    • 0025727953 scopus 로고
    • Properties of the mitochondrial membrane and carnitine palmitoyltransferase I in the periportal and perivenous zone of the liver
    • Castro J, Cortés JP, Guzmán M. Properties of the mitochondrial membrane and carnitine palmitoyltransferase I in the periportal and perivenous zone of the liver. Biochem Pharmacol 1991;41:1987-1995.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1987-1995
    • Castro, J.1    Cortés, J.P.2    Guzmán, M.3
  • 30
    • 0021091897 scopus 로고
    • Ethanol-related changes in liver microsomes and mitochondria from the monkey, Macaca fascicularis
    • Cunningham CC, Botenus RE, Spach PI, Rudel LL. Ethanol-related changes in liver microsomes and mitochondria from the monkey, Macaca fascicularis. Alcohol Clin Exp Res 1983;7:424-430.
    • (1983) Alcohol Clin Exp Res , vol.7 , pp. 424-430
    • Cunningham, C.C.1    Botenus, R.E.2    Spach, P.I.3    Rudel, L.L.4
  • 32
    • 0035896645 scopus 로고    scopus 로고
    • Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location
    • Fiermonte G, Dolce V, Palmieri L, Ventura M, Runswick MJ, Palmieri F, Walker JE. Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. J Biol Chem 2001;276:8225-8230.
    • (2001) J Biol Chem , vol.276 , pp. 8225-8230
    • Fiermonte, G.1    Dolce, V.2    Palmieri, L.3    Ventura, M.4    Runswick, M.J.5    Palmieri, F.6    Walker, J.E.7
  • 33
    • 0035910408 scopus 로고    scopus 로고
    • Identification in saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate
    • Palmieri L, Agrimi G, Runswick MJ, Fearneley IA, Palmieri F, Walker JE. Identification in saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. J Biol Chem 2001;276:1916-1922.
    • (2001) J Biol Chem , vol.276 , pp. 1916-1922
    • Palmieri, L.1    Agrimi, G.2    Runswick, M.J.3    Fearneley, I.A.4    Palmieri, F.5    Walker, J.E.6
  • 34
    • 0016817744 scopus 로고
    • Molecular injury to mitochondria produced by ethanol and acetaldehyde
    • Cederbaum AI, Rubin E. Molecular injury to mitochondria produced by ethanol and acetaldehyde. Fed Proc 1975;34:2045-2051.
    • (1975) Fed Proc , vol.34 , pp. 2045-2051
    • Cederbaum, A.I.1    Rubin, E.2
  • 35
    • 0025312660 scopus 로고
    • The effects of chronic ethanol consumption on hepatic mitochondrial energy metabolism
    • Cunningham CC, Coleman WB, Spach PI. The effects of chronic ethanol consumption on hepatic mitochondrial energy metabolism. Alcohol Alcohol 1990;25:127-136.
    • (1990) Alcohol Alcohol , vol.25 , pp. 127-136
    • Cunningham, C.C.1    Coleman, W.B.2    Spach, P.I.3
  • 36
    • 0017690686 scopus 로고
    • ATP metabolism in an ethanol induced fatty liver
    • Gordon E. ATP metabolism in an ethanol induced fatty liver. Biochem Pharmacol 1977;26:1229-1234.
    • (1977) Biochem Pharmacol , vol.26 , pp. 1229-1234
    • Gordon, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.