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Volumn 86, Issue 9, 2008, Pages 2003-2015

Folic acid deficiency increases delayed neuronal death, DNA damage, platelet endothelial cell adhesion molecule-1 immunoreactivity, and gliosis in the hippocampus after transient cerebral ischemia

Author keywords

8 hydroxy 2 deoxyguanosine; Folic acid deficiency; Glia; Platelet endothelial cell adhesion molecule 1; Transient forebrain ischemia

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CD31 ANTIGEN; DNA; FOLIC ACID;

EID: 48249107129     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21647     Document Type: Article
Times cited : (19)

References (46)
  • 1
    • 0042672758 scopus 로고    scopus 로고
    • 2 stimulation and hydroxyl radical generation in transient cerebral ischemia
    • 2 stimulation and hydroxyl radical generation in transient cerebral ischemia. J Neurosci Res 73:308-315.
    • (2003) J Neurosci Res , vol.73 , pp. 308-315
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 3
    • 23444444518 scopus 로고    scopus 로고
    • Lipid signaling in neural plasticity, brain repair, and neuroprotection
    • Bazan NG. 2005. Lipid signaling in neural plasticity, brain repair, and neuroprotection. Mol Neurobiol 32:89-103.
    • (2005) Mol Neurobiol , vol.32 , pp. 89-103
    • Bazan, N.G.1
  • 5
    • 0141739581 scopus 로고    scopus 로고
    • Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils
    • Candelario-Jalil E, Alvarez D, Merino N, León OS. 2003. Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils. Neurosci Res 47:245-253.
    • (2003) Neurosci Res , vol.47 , pp. 245-253
    • Candelario-Jalil, E.1    Alvarez, D.2    Merino, N.3    León, O.S.4
  • 6
    • 0034765766 scopus 로고    scopus 로고
    • Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils
    • Candelario-Jalil E, Mhadu NH, Al-Dalain SM, Martínez G, León OS. 2001. Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils. Neurosci Res 41:233-241.
    • (2001) Neurosci Res , vol.41 , pp. 233-241
    • Candelario-Jalil, E.1    Mhadu, N.H.2    Al-Dalain, S.M.3    Martínez, G.4    León, O.S.5
  • 7
    • 0034936018 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro
    • Crott JW, Mashiyama ST, Ames BN, Fenech MF. 2001. Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro. Carcinogenesis 22:1019-1025.
    • (2001) Carcinogenesis , vol.22 , pp. 1019-1025
    • Crott, J.W.1    Mashiyama, S.T.2    Ames, B.N.3    Fenech, M.F.4
  • 8
    • 0037020838 scopus 로고    scopus 로고
    • PECAM-1 (CD31) homophilic interaction up-regulates α6β1 on transmigrated neutrophils in vivo and plays a functional role in the ability of α6 integrins to mediate leukocyte migration through the perivascular basement membrane
    • Dangerfield J, Larbi KY, Huang MT, Dewar A, Nourshargh S. 2002. PECAM-1 (CD31) homophilic interaction up-regulates α6β1 on transmigrated neutrophils in vivo and plays a functional role in the ability of α6 integrins to mediate leukocyte migration through the perivascular basement membrane. J Exp Med 196:1201-1211.
    • (2002) J Exp Med , vol.196 , pp. 1201-1211
    • Dangerfield, J.1    Larbi, K.Y.2    Huang, M.T.3    Dewar, A.4    Nourshargh, S.5
  • 9
    • 0032713838 scopus 로고    scopus 로고
    • Folic acid deficiency and cancer: Mechanisms of DNA instability
    • Duthie SJ. 1999. Folic acid deficiency and cancer: mechanisms of DNA instability. Br Med Bull 55:578-592.
    • (1999) Br Med Bull , vol.55 , pp. 578-592
    • Duthie, S.J.1
  • 10
    • 0032429906 scopus 로고    scopus 로고
    • Stroke risk factors and stroke prevention
    • Elkind MS, Sacco RL. 1998. Stroke risk factors and stroke prevention. Semin Neurol 18:429-440.
    • (1998) Semin Neurol , vol.18 , pp. 429-440
    • Elkind, M.S.1    Sacco, R.L.2
  • 12
    • 0029012077 scopus 로고
    • Serum folate and risk for ischemic stroke. First national health and nutrition examination survey epidemiologic follow-up study
    • Giles WH, Kittner SJ, Anda RF, Croft JB, Casper ML. 1995. Serum folate and risk for ischemic stroke. First national health and nutrition examination survey epidemiologic follow-up study. Stroke 26:1166-1170.
    • (1995) Stroke , vol.26 , pp. 1166-1170
    • Giles, W.H.1    Kittner, S.J.2    Anda, R.F.3    Croft, J.B.4    Casper, M.L.5
  • 13
    • 13444291515 scopus 로고    scopus 로고
    • Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia
    • Glantz L, Avramovich A, Trembovler V, Gurvitz V, Kohen R, Eidelman LA, Shohami E. 2005. Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia. Exp Neurol 192:117-124.
    • (2005) Exp Neurol , vol.192 , pp. 117-124
    • Glantz, L.1    Avramovich, A.2    Trembovler, V.3    Gurvitz, V.4    Kohen, R.5    Eidelman, L.A.6    Shohami, E.7
  • 14
    • 0034079862 scopus 로고    scopus 로고
    • Free radicals and antioxidants in the year 2000. A historical look to the future
    • Gutteridge JM, Halliwell B. 2000. Free radicals and antioxidants in the year 2000. A historical look to the future. Ann N Y Acad Sci 899:136-147.
    • (2000) Ann N Y Acad Sci , vol.899 , pp. 136-147
    • Gutteridge, J.M.1    Halliwell, B.2
  • 15
    • 21344459081 scopus 로고    scopus 로고
    • Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus
    • Hwang IK, Eum WS, Yoo KY, Cho JH, Kim DW, Choi SH, Kang TC, Kwon OS, Kang JH, Choi SY, Won MH. 2005a. Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus. Free Radic Biol Med 39:392-402.
    • (2005) Free Radic Biol Med , vol.39 , pp. 392-402
    • Hwang, I.K.1    Eum, W.S.2    Yoo, K.Y.3    Cho, J.H.4    Kim, D.W.5    Choi, S.H.6    Kang, T.C.7    Kwon, O.S.8    Kang, J.H.9    Choi, S.Y.10    Won, M.H.11
  • 17
    • 34547633289 scopus 로고    scopus 로고
    • Aquaporin 9 changes in pyramidal cells before and is expressed in astrocytes after delayed neuronal death in the ischemic hippocampal CA1 region of the gerbil
    • Hwang IK, Yoo KY, Li H, Lee BH, Suh HW, Kwon YG, Won MH. 2007. Aquaporin 9 changes in pyramidal cells before and is expressed in astrocytes after delayed neuronal death in the ischemic hippocampal CA1 region of the gerbil. J Neurosci Res 85:2470-2479.
    • (2007) J Neurosci Res , vol.85 , pp. 2470-2479
    • Hwang, I.K.1    Yoo, K.Y.2    Li, H.3    Lee, B.H.4    Suh, H.W.5    Kwon, Y.G.6    Won, M.H.7
  • 19
    • 2342562573 scopus 로고    scopus 로고
    • Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke
    • Khan M, Sekhon B, Jatana M, Giri S, Gilg AG, Sekhon C, Singh I, Singh AK. 2004. Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. J Neurosci Res 76:519-527.
    • (2004) J Neurosci Res , vol.76 , pp. 519-527
    • Khan, M.1    Sekhon, B.2    Jatana, M.3    Giri, S.4    Gilg, A.G.5    Sekhon, C.6    Singh, I.7    Singh, A.K.8
  • 20
    • 0022483433 scopus 로고
    • A reversible type of neuronal injury following ischemia in the gerbil hippocampus
    • Kirino T, Tamura A, Sano K. 1986. A reversible type of neuronal injury following ischemia in the gerbil hippocampus. Stroke 17:455-459.
    • (1986) Stroke , vol.17 , pp. 455-459
    • Kirino, T.1    Tamura, A.2    Sano, K.3
  • 21
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • Kirino T. 1982. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 239:57-69.
    • (1982) Brain Res , vol.239 , pp. 57-69
    • Kirino, T.1
  • 22
    • 0031984256 scopus 로고    scopus 로고
    • Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: Preference for cysteine
    • Kranich O, Dringen R, Sandberg M, Hamprecht B. 1998. Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cysteine. Glia 22:11-18.
    • (1998) Glia , vol.22 , pp. 11-18
    • Kranich, O.1    Dringen, R.2    Sandberg, M.3    Hamprecht, B.4
  • 23
    • 0034666267 scopus 로고    scopus 로고
    • Homocysteine ehcits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
    • Kruman II, Culmsee C, Chan SL, Kruman Y, Guo Z, Penix L, Mattson MP. 2000. Homocysteine ehcits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J Neurosci 20:6920-6926.
    • (2000) J Neurosci , vol.20 , pp. 6920-6926
    • Kruman, I.I.1    Culmsee, C.2    Chan, S.L.3    Kruman, Y.4    Guo, Z.5    Penix, L.6    Mattson, M.P.7
  • 24
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
    • Kruman II, Kumaravel TS, Lohani A, Pedersen WA, Cuder RG, Kruman Y, Haughey N, Lee J, Evans M, Mattson MP. 2002. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 22:1752-1762.
    • (2002) J Neurosci , vol.22 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3    Pedersen, W.A.4    Cuder, R.G.5    Kruman, Y.6    Haughey, N.7    Lee, J.8    Evans, M.9    Mattson, M.P.10
  • 25
    • 22544476559 scopus 로고    scopus 로고
    • Kruman II, Mouton PR, Emokpae R Jr, Cuder RG, Mattson MP. 2005. Folate deficiency inhibits proliferation of adult hippocampal progenitors. Neuroreport 16:1055-1059.
    • Kruman II, Mouton PR, Emokpae R Jr, Cuder RG, Mattson MP. 2005. Folate deficiency inhibits proliferation of adult hippocampal progenitors. Neuroreport 16:1055-1059.
  • 26
    • 0038792636 scopus 로고    scopus 로고
    • 6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mud cognitive impairment
    • 6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mud cognitive impairment. Dement Geriatr Cogn Disord 16:145-150.
    • (2003) Dement Geriatr Cogn Disord , vol.16 , pp. 145-150
    • Lehmann, M.1    Regland, B.2    Blennow, K.3    Gottfries, C.G.4
  • 30
    • 0031660612 scopus 로고    scopus 로고
    • Role of PECAM-1 in the adherence of PMN to hypoxic endothelial cells
    • Michiels C, Arnould T, Remacle J. 1998. Role of PECAM-1 in the adherence of PMN to hypoxic endothelial cells. Cell Adhes Commun 5:367-374.
    • (1998) Cell Adhes Commun , vol.5 , pp. 367-374
    • Michiels, C.1    Arnould, T.2    Remacle, J.3
  • 32
    • 0141533205 scopus 로고    scopus 로고
    • New roles for astrocytes: Redefining the functional architecture of the brain
    • Nedergaard M, Ransom B, Goldman SA. 2003. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 26:523-530.
    • (2003) Trends Neurosci , vol.26 , pp. 523-530
    • Nedergaard, M.1    Ransom, B.2    Goldman, S.A.3
  • 34
    • 4644301413 scopus 로고    scopus 로고
    • Influence of chemical and ischemic preconditioning on cytokine expression after focal brain ischemia
    • Pera J, Zawadzka M, Kaminska B, Szczudlik A. 2004. Influence of chemical and ischemic preconditioning on cytokine expression after focal brain ischemia. J Neurosci Res 78:132-140.
    • (2004) J Neurosci Res , vol.78 , pp. 132-140
    • Pera, J.1    Zawadzka, M.2    Kaminska, B.3    Szczudlik, A.4
  • 35
    • 0031428480 scopus 로고    scopus 로고
    • Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats
    • Pogribny IP, Muskhelishvili L, Miller BJ, James SJ. 1997. Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats. Carcinogenesis 18:2071-2076.
    • (1997) Carcinogenesis , vol.18 , pp. 2071-2076
    • Pogribny, I.P.1    Muskhelishvili, L.2    Miller, B.J.3    James, S.J.4
  • 36
    • 0020067965 scopus 로고
    • Temporal profile of neuronal damage in a model of transient forebrain ischemia
    • Pulsinelli WA, Brierley JB, Plum F. 1982. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 11:491-498.
    • (1982) Ann Neurol , vol.11 , pp. 491-498
    • Pulsinelli, W.A.1    Brierley, J.B.2    Plum, F.3
  • 37
    • 0034714392 scopus 로고    scopus 로고
    • Fluoro-Jade B: A high affinity fluorescent marker for the localization of neuronal degeneration
    • Schmued LC, Hopkins KJ. 2000. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res 874:123-130.
    • (2000) Brain Res , vol.874 , pp. 123-130
    • Schmued, L.C.1    Hopkins, K.J.2
  • 38
    • 0032443019 scopus 로고    scopus 로고
    • Folic acid, homocysteine, and one-carbon metabolism: A review of the essential biochemistry
    • Scott JM, Weir DG. 1998. Folic acid, homocysteine, and one-carbon metabolism: a review of the essential biochemistry. J Cardiovasc Risk 5:223-227.
    • (1998) J Cardiovasc Risk , vol.5 , pp. 223-227
    • Scott, J.M.1    Weir, D.G.2
  • 39
    • 0345169718 scopus 로고    scopus 로고
    • DACH-LIGA Homocystein (German, Austrian and Swiss Homocysteine Society): Consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations
    • Stanger O, Herrmann W, Pietrzik K, Fowler B, Geisel J, Dierkes J, Weger M. 2003. DACH-LIGA Homocystein (German, Austrian and Swiss Homocysteine Society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med 41:1392-1403.
    • (2003) Clin Chem Lab Med , vol.41 , pp. 1392-1403
    • Stanger, O.1    Herrmann, W.2    Pietrzik, K.3    Fowler, B.4    Geisel, J.5    Dierkes, J.6    Weger, M.7
  • 40
    • 0031028169 scopus 로고    scopus 로고
    • The role of folic acid in deficiency states and prevention of disease
    • Swain RA, St. Clair L. 1997. The role of folic acid in deficiency states and prevention of disease. J Fam Pract 44:138-144.
    • (1997) J Fam Pract , vol.44 , pp. 138-144
    • Swain, R.A.1    St. Clair, L.2
  • 41
    • 0037093669 scopus 로고    scopus 로고
    • Neuroprotective effects of carnosine and homocamosine on pheochromocytoma PC12 cells exposed to ischemia
    • Tabakman R, Lazarovici P, Kohen R. 2002. Neuroprotective effects of carnosine and homocamosine on pheochromocytoma PC12 cells exposed to ischemia. J Neurosci Res 68:463-649.
    • (2002) J Neurosci Res , vol.68 , pp. 463-649
    • Tabakman, R.1    Lazarovici, P.2    Kohen, R.3
  • 43
    • 0035970836 scopus 로고    scopus 로고
    • The alterations of N-methyl-D-aspartate receptor expressions and oxidative DNA damage in the CA1 area at the early time after ischemia-reperfusion insult
    • Won MH, Kang TC, Park SK, Jeon GS, Kim Y, Seo JH, Choi E, Chung MH, Cho SS. 2001. The alterations of N-methyl-D-aspartate receptor expressions and oxidative DNA damage in the CA1 area at the early time after ischemia-reperfusion insult. Neurosci Lett 301:139-142.
    • (2001) Neurosci Lett , vol.301 , pp. 139-142
    • Won, M.H.1    Kang, T.C.2    Park, S.K.3    Jeon, G.S.4    Kim, Y.5    Seo, J.H.6    Choi, E.7    Chung, M.H.8    Cho, S.S.9
  • 44
    • 30444438526 scopus 로고    scopus 로고
    • Postishemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis
    • Xia CF, Yin H, Borlongan CV, Chao J, Chao L. 2006. Postishemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis. Exp Neurol 197:521-530.
    • (2006) Exp Neurol , vol.197 , pp. 521-530
    • Xia, C.F.1    Yin, H.2    Borlongan, C.V.3    Chao, J.4    Chao, L.5
  • 45
    • 0033118493 scopus 로고    scopus 로고
    • Moderate hyperhomocyst(e)inemia is associated with the presence of coronary artery disease and the severity of coronary atherosclerosis in Koreans
    • Yoo JH, Park JE, Hong KP, Lee SH, Kim DK, Lee WR, Park SC. 1999. Moderate hyperhomocyst(e)inemia is associated with the presence of coronary artery disease and the severity of coronary atherosclerosis in Koreans. Thromb Res 94:45-52.
    • (1999) Thromb Res , vol.94 , pp. 45-52
    • Yoo, J.H.1    Park, J.E.2    Hong, K.P.3    Lee, S.H.4    Kim, D.K.5    Lee, W.R.6    Park, S.C.7
  • 46
    • 0034813226 scopus 로고    scopus 로고
    • Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke
    • Yoo JH, Lee SC. 2001. Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke. Atherosclerosis 158:425-430.
    • (2001) Atherosclerosis , vol.158 , pp. 425-430
    • Yoo, J.H.1    Lee, S.C.2


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