Exploring the odorant binding site a G-protein-couple olfactory receptor

Current Computer-Aided Drug Design

Volumn 4, Issue 2, 2008, Pages 123-131

  Katada, Sayako ^a   Hirokawa, Takatsugu ^b   Touhara, Kazushige ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Computer modeling; G protein couple receptor; Ligand binding; Odorant; Olfactory receptor; Rhodopsin; Site directed mutagenesis

Indexed keywords

ODORS; PROTEINS;

BINDING-SITES; COMPUTER MODELS; G PROTEIN; G PROTEIN COUPLED RECEPTORS; G-PROTEIN-COUPLE RECEPTOR; LIGAND BINDING; ODORANT; OLFACTORY RECEPTORS; RHODOPSIN; SITE DIRECTED MUTAGENESIS;

LIGANDS;

3 ETHOXY 4 HYDROXYBENZALDEHYDE; 3,4 DIETHOXYBENZALDEHYDE; 4 HYDROXY 3 METHYLBENZALDEHYDE; ACETYLEUGENOL; AMINO ACID DERIVATIVE; BACTERIORHODOPSIN; BENZALDEHYDE DERIVATIVE; BETA ADRENERGIC RECEPTOR; EUGENOL; G PROTEIN COUPLED RECEPTOR; ISOEUGENOL; ISOSAFROLE; METHYL ISOEUGENOL; METHYLEUGENOL; MUSCARINIC RECEPTOR; PURINERGIC P2Y RECEPTOR; RECEPTOR BLOCKING AGENT; RHODOPSIN; SYRINGALDEHYDE; VANILLIC ACID; VANILLIN;

AUTOMATION; COMPUTER MODEL; COMPUTER PROGRAM; DRUG BINDING SITE; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG TARGETING; EXPERIMENTAL DESIGN; HUMAN; LIGAND BINDING; MATHEMATICAL COMPUTING; MOLECULAR MECHANICS; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; OLFACTORY SYSTEM; POINT MUTATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SEQUENCE ALIGNMENT; VALIDATION STUDY;

EID: 48249103160     PISSN: 15734099     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340908784533247     Document Type: Review

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