Provisional hypotheses for the molecular genetics of cognitive development: Imaging genetic pathways in the anterior cingulate cortex

Biological Psychology

Volumn 79, Issue 1, 2008, Pages 23-29

  Fossella, John ^a   Fan, Jin ^a   Liu, Xun ^a   Guise, Kevin ^a   Brocki, Karin ^a   Hof, Patrick R ^a   Kittappa, Raja ^b   McKay, Ronald ^b   Posner, Michael ^c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UNIVERSITY OF OREGON   (United States)

Author keywords

Brain; Cingulate; Development; Genetic; Imaging

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; CATECHOL METHYLTRANSFERASE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; FIBROBLAST GROWTH FACTOR 8; MUSCARINIC M5 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NEUROKININ A; OXYGEN; SECRETED FRIZZLED RELATED PROTEIN 1; SONIC HEDGEHOG PROTEIN; SUBSTANCE P; TACHYKININ;

ALLELE; ARTICLE; CINGULATE GYRUS; COGNITIVE DEVELOPMENT; ELECTROENCEPHALOGRAM; GENE EXPRESSION; GENE FUNCTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HYPOTHESIS; MOLECULAR GENETICS; MOLECULAR MODEL; NEUROANATOMY; NEUROIMAGING; NEUROPHYSIOLOGY; NONHUMAN; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; SYNAPSE; SYNAPTIC TRANSMISSION;

ALLELES; ANIMALS; CEREBRAL CORTEX; COGNITION; GENOTYPE; HUMANS; MAGNETIC RESONANCE IMAGING; MOLECULAR BIOLOGY; OXYGEN;

EID: 47949103256     PISSN: 03010511     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsycho.2007.12.006     Document Type: Article

References (87)

1. Anokhin A.P., Heath A.C., and Myers E. Genetics, prefrontal cortex, and cognitive control: a twin study of event-related brain potentials in a response inhibition task. Neuroscience Letter 368 (2004) 314-318
2. Araya R., Noguchi T., Yuhki M., Kitamura N., Higuchi M., Saido T.C., Seki K., Itohara S., Kawano M., Tanemura K., Takashima A., Yamada K., Kondoh Y., Kanno I., Wess J., and Yamada M. Loss of M5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice. Neurobiology of Disease 24 (2006) 334-344
3. Avishai-Eliner S., Hatalski C.G., Tabachnik E., Eghbal-Ahmadi M., and Baram T.Z. Differential regulation of glucocorticoid receptor messenger RNA (GR-mRNA) by maternal deprivation in immature rat hypothalamus and limbic regions. Brain Research Device-Brain Research 114 (1999) 265-268
4. Bagni C., and Greenough W.T. From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nature Reviews. Neuroscience 6 (2005) 376-387
5. Beglopoulos V., Montag-Sallaz M., Rohlmann A., Piechotta K., Ahmad M., Montag D., and Missler M. Neurexophilin 3 is highly localized in cortical and cerebellar regions and is functionally important for sensorimotor gating and motor coordination. Molecular Cell Biology 25 (2005) 7278-7288
6. Bellon A. New genes associated with schizophrenia in neurite formation: a review of cell culture experiments. Molecular Psychiatry 12 (2007) 620-629
7. Benes F.M. Emerging principles of altered neural circuitry in schizophrenia. Brain Research-Brain Research Review 31 (2000) 251-269
8. Bilkei-Gorzo A., Racz I., Michel K., and Zimmer A. Diminished anxiety- and depression-related behaviors in mice with selective deletion of the Tac1 gene. Journal of Neuroscience 22 (2002) 10046-10052
9. Botvinick M.M., Braver T.S., Barch D.M., Carter C.S., and Cohen J.D. Conflict monitoring and cognitive control. Psychology Review 108 (2001) 624-652
10. Botvinick M.M., Cohen J.D., and Carter C.S. Conflict monitoring and anterior cingulate cortex: an update. Trends Cognitive Science 8 (2004) 539-546
11. Cannon T.D., Huttunen M.O., Lonnqvist J., Tuulio-Henriksson A., Pirkola T., Glahn D., Finkelstein J., Hietanen M., Kaprio J., and Koskenvuo M. The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. American Journal of Human Genetics 67 (2000) 369-382
12. Clapp W.C., Kirk I.J., Hamm J.P., Shepherd D., and Teyler T.J. Induction of LTP in the human auditory cortex by sensory stimulation. European Journal of Neuroscience 22 (2005) 1135-1140
13. Clapp W.C., Zaehle T., Lutz K., Marcar V.L., Kirk I.J., Hamm J.P., Teyler T.J., Corballis M.C., and Jancke L. Effects of long-term potentiation in the human visual cortex: a functional magnetic resonance imaging study. Neuroreport 16 (2005) 1977-1980
14. Cohen Jr. M.M. The hedgehog signaling network. American Journal Medical Genetics A 123 (2003) 5-28
15. Corbetta M., and Shulman G.L. Human cortical mechanisms of visual attention during orienting and search. Philosophical Transactions of Royal Society London B Biological Sciences 353 (1998) 1353-1362
16. Derbyshire S.W., Whalley M.G., Stenger V.A., and Oakley D.A. Cerebral activation during hypnotically induced and imagined pain. Neuroimage 23 (2004) 392-401
17. Dodart J.C., Mathis C., Bales K.R., Paul S.M., and Ungerer A. Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F beta-amyloid precursor protein. Neuroscience Letter 277 (1999) 49-52
18. Egan M.F., Goldberg T.E., Kolachana B.S., Callicott J.H., Mazzanti C.M., Straub R.E., Goldman D., and Weinberger D.R. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proceedings of National Academy of Science USA 98 (2001) 6917-6922
19. Eisenberger N.I., Lieberman M.D., and Williams K.D. Does rejection hurt? An FMRI study of social exclusion. Science 302 (2003) 290-292
20. Eslinger P.J., and Damasio A.R. Severe disturbance of higher cognition after bilateral frontal lobe ablation: patient EVR. Neurology 35 (1985) 1731-1741
21. Fan J., Wu Y., Fossella J.A., and Posner M.I. Assessing the heritability of attentional networks. BMC Neuroscience 2 (2001) 14
22. Fan J., Fossella J., Sommer T., Wu Y., and Posner M.I. Mapping the genetic variation of executive attention onto brain activity. Proceedings of National Academy of Science USA 100 (2003) 7406-7411
23. Fan J., Byrne J., Worden M.S., Guise K.G., McCandliss B.D., Fossella J., and Posner M.I. The relation of brain oscillations to attentional networks. Journal of Neuroscience 27 (2007) 6197-6206
24. Fan J., Hof P.R., Guise K.G., Fossella J.A., and Posner M.I. The functional integration of the anterior cingulate cortex during conflict processing. Cerebral Cortex (2007)
25. Fan J., and Posner M. Human attentional networks. Psychiatrische Praxis 31 Suppl. 2 (2004) S210-S214
26. Fossella J., Sommer T., Fan J., Wu Y., Swanson J.M., Pfaff D.W., and Posner M.I. Assessing the molecular genetics of attention networks. BMC Neuroscience 3 (2002) 14
27. Fossella J., Green A.E., and Fan J. Evaluation of a structural polymorphism in the ankyrin repeat and kinase domain containing 1(ANKK1) gene and the activation of executive attention networks. Cognitive Affection Behavivour Neuroscience 6 (2006) 71-78
28. Fukuchi-Shimogori T., and Grove E.A. Neocortex patterning by the secreted signaling molecule FGF8. Science 294 (2001) 1071-1074
29. Fukuchi-Shimogori T., and Grove E.A. Emx2 patterns the neocortex by regulating FGF positional signaling. Nature Neuroscience 6 (2003) 825-831
30. Goghari V.M., Rehm K., Carter C.S., and MacDonald III A.W. Regionally specific cortical thinning and gray matter abnormalities in the healthy relatives of schizophrenia patients. Cerebral Cortex 17 (2007) 415-424
31. Greer J.M., and Wynshaw-Boris A. Pten and the brain: sizing up social interaction. Neuron 50 (2006) 343-345
32. Hebert J.M., Mishina Y., and McConnell S.K. BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron 35 (2002) 1029-1041
33. Heinz A., Braus D.F., Smolka M.N., Wrase J., Puls I., Hermann D., Klein S., Grusser S.M., Flor H., Schumann G., Mann K., and Buchel C. Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter. Nature Neuroscience 8 (2005) 20-21
34. Heussler H.S., Suri M., Young I.D., and Muenke M. Extreme variability of expression of a Sonic Hedgehog mutation: attention difficulties and holoprosencephaly. Archives of Disease in Childhood 86 (2002) 293-296
35. Janer K.W., and Pardo J.V. Deficits in selective attention follow in bilateral anterior cingulotomy. Journal of Cognitive Neuroscience 3 (1991) 231-241
36. Kaga Y., Shoemaker W.J., Furusho M., Bryant M., Rosenbluth J., Pfeiffer S.E., Oh L., Rasband M., Lappe-Siefke C., Yu K., Ornitz D.M., Nave K.A., and Bansal R. Mice with conditional inactivation of fibroblast growth factor receptor-2 signaling in oligodendrocytes have normal myelin but display dramatic hyperactivity when combined with Cnp1 inactivation. Journal of Neuroscience 26 (2006) 12339-12350
37. Karmiloff-Smith A. Atypical epigenesis. Developmental Science 10 (2007) 84-88
38. Kendler K.S. Reflections on the relationship between psychiatric genetics and psychiatric nosology. American Journal of Psychiatry 163 (2006) 1138-1146
39. Kinsman S.L. White matter imaging in holoprosencephaly in children. Current Opinion Neurology 17 (2004) 115-119
40. Ko S.W., Ao H.S., Mendel A.G., Qiu C.S., Wei F., Milbrandt J., and Zhuo M. Transcription factor Egr-1 is required for long-term fear memory and anxiety. Sheng Li Xue Bao 57 (2005) 421-432
41. Kwon C.H., Luikart B.W., Powell C.M., Zhou J., Matheny S.A., Zhang W., Li Y., Baker S.J., and Parada L.F. Pten regulates neuronal arborization and social interaction in mice. Neuron 50 (2006) 377-388
42. Ladenheim B., Krasnova I.N., Deng X., Oyler J.M., Polettini A., Moran T.H., Huestis M.A., and Cadet J.L. Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6. Molecular Pharmacology 58 (2000) 1247-1256
43. Liauw J., Wu L.J., and Zhuo M. Calcium-stimulated adenylyl cyclases required for long-term potentiation in the anterior cingulate cortex. Journal of Neurophysiology 94 (2005) 878-882
44. Logothetis N.K. The ins and outs of fMRI signals. Nature Neuroscience 10 (2007) 1230-1232
45. Lu H., Patel S., Luo F., Li S.J., Hillard C.J., Ward B.D., and Hyde J.S. Spatial correlations of laminar BOLD and CBV responses to rat whisker stimulation with neuronal activity localized by Fos expression. Magnetic Resonance Medicine 52 (2004) 1060-1068
46. Lyuksyutova A.I., Lu C.C., Milanesio N., King L.A., Guo N., Wang Y., Nathans J., Tessier-Lavigne M., and Zou Y. Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science 302 (2003) 1984-1988
47. Mattay V.S., Goldberg T.E., Fera F., Hariri A.R., Tessitore A., Egan M.F., Kolachana B., Callicott J.H., and Weinberger D.R. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proceedings of National Academy of Science USA 100 (2003) 6186-6191
48. Mehmet H., Yue X., Squier M.V., Lorek A., Cady E., Penrice J., Sarraf C., Wylezinska M., Kirkbride V., Cooper C., et al. Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insult. Neuroscience Letter 181 (1994) 121-125
49. Mesulam M.M. A cortical network for directed attention and unilateral neglect. Annals of Neurology 10 (1981) 309-325
50. Meyer-Lindenberg A., Buckholtz J.W., Kolachana B.A.R.H., Pezawas L., Blasi G., Wabnitz A., Honea R., Verchinski B., Callicott J.H., Egan M., Mattay V., and Weinberger D.R. Neural mechanisms of genetic risk for impulsivity and violence in humans. Proceedings of National Academy of Science USA 103 (2006) 6269-6274
51. Monuki E.S., Porter F.D., and Walsh C.A. Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway. Neuron 32 (2001) 591-604
52. Mueller C., Patel S., Irons M., Antshel K., Salen G., Tint G.S., and Bay C. Normal cognition and behavior in a Smith-Lemli-Opitz syndrome patient who presented with Hirschsprung disease. American Journal of Medical Genetics A 123 (2003) 100-106
53. Murase S., and McKay R.D. A specific survival response in dopamine neurons at most risk in Parkinson's disease. Journal of Neuroscience 26 (2006) 9750-9760
54. Ogden C.A., Rich M.E., Schork N.J., Paulus M.P., Geyer M.A., Lohr J.B., Kuczenski R., and Niculescu A.B. Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Molecular Psychiatry 9 (2004) 1007-1029
55. Ogura H., Aruga J., and Mikoshiba K. Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders. Behaviour Genetics 31 (2001) 317-324
56. Panchision D.M., Pickel J.M., Studer L., Lee S.H., Turner P.A., Hazel T.G., and McKay R.D. Sequential actions of BMP receptors control neural precursor cell production and fate. Genes and Development 15 (2001) 2094-2110
57. Pardo P.J., Knesevich M.A., Vogler G.P., Pardo J.V., Towne B., Cloninger C.R., and Posner M.I. Genetic and state variables of neurocognitive dysfunction in schizophrenia: a twin study [in process citation]. Schizophrenia Bulletin 26 (2000) 459-477
58. Pezawas L., Meyer-Lindenberg A., Drabant E.M., Verchinski B.A., Munoz K.E., Kolachana B.S., Egan M.F., Mattay V.S., Hariri A.R., and Weinberger D.R. 5-HTTLPR polymorphism impacts human cingulated-amygdala interactions: a genetic susceptibility mechanism for depression. Nature Neuroscience 8 (2005) 828-834
59. Raichle M.E., and Mintun M.A. Brain work and brain imaging. Annual Review of Neuroscience 29 (2006) 449-476
60. Raz A., Fan J., and Posner M.I. Hypnotic suggestion reduces conflict in the human brain. Proceedings of National Academy of Science USA 102 (2005) 9978-9983
61. Ressler K.J., and Mayberg H.S. Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic. Nature Neuroscience 10 (2007) 1116-1124
62. Romeo R.D., Fossella J.A., Bateup H.S., Sisti H.M., Brake W.G., and McEwen B.S. Maternal separation suppresses TGF alpha mRNA expression in the prefrontal cortex of male and female neonatal C57BL/6 mice. Brain Research Device-Brain Research 152 (2004) 73-77
63. Rutter M., Moffitt T.E., and Caspi A. Gene-environment interplay and psychopathology: multiple varieties but real effects. Journal of Child Psychology and Psychiatry 47 (2006) 226-261
64. Scerif G., and Karmiloff-Smith A. The dawn of cognitive genetics? Crucial developmental caveats. Trends Cognitive Science 9 (2005) 126-135
65. Sesack S.R., Hawrylak V.A., Guido M.A., and Levey A.I. Cellular and subcellular localization of the dopamine transporter in rat cortex. Advanced Pharmacology 42 (1998) 171-174
66. Shaw P., Gornick M., Lerch J., Addington A., Seal J., Greenstein D., Sharp W., Evans A., Giedd J.N., Castellanos F.X., and Rapoport J.L. Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder. Archives Genetics Psychiatry 64 (2007) 921-931
67. Sheese B.E., Voelker P.M., Rothbart M.K., and Posner M.I. Parenting quality interacts with genetic variation in dopamine receptor D4 to influence temperament in early childhood. Developmental Psychopathology 19 (2007) 1039-1046
68. Sikes R.W., and Vogt B.A. Nociceptive neurons in area 24 of rabbit cingulate cortex. Journal of Neurophysiology 68 (1992) 1720-1732
69. Sugino K., Hempel C.M., Miller M.N., Hattox A.M., Shapiro P., Wu C., Huang Z.J., and Nelson S.B. Molecular taxonomy of major neuronal classes in the adult mouse forebrain. Nature Neuroscience 9 (2006) 99-107
70. Takahashi T., Kinsman S., Makris N., Grant E., Haselgrove C., McInerney S., Kennedy D.N., Takahashi T., Fredrickson K., Mori S., and Caviness V.S. Semilobar holoprosencephaly with midline 'seam': a topologic and morphogenetic model based upon MRI analysis. Cerebral Cortex 13 (2003) 1299-1312
71. Toyoda H., Wu L.J., Zhao M.G., Xu H., Jia Z., and Zhuo M. Long-term depression requires postsynaptic AMPA GluR2 receptor in adult mouse cingulate cortex. Journal of Cell Physiology 211 (2007) 336-343
72. Vogt B.A. Pain and emotion interactions in subregions of the cingulate gyrus. Nature Reviews. Neuroscience 6 (2005) 533-544
73. Wang K., Fan J., Dong Y., Wang C.Q., Lee T.M., and Posner M.I. Selective impairment of attentional networks of orienting and executive control in schizophrenia. Schizophrenia Research 78 (2005) 235-241
74. Wei F., and Zhuo M. Potentiation of sensory responses in the anterior cingulate cortex following digit amputation in the anaesthetised rat. Journal of Physiology 532 (2001) 823-833
75. Wei F., Li P., and Zhuo M. Loss of synaptic depression in mammalian anterior cingulate cortex after amputation. Journal of Neuroscience 19 (1999) 9346-9354
76. Wei F., Wang G.D., Kerchner G.A., Kim S.J., Xu H.M., Chen Z.F., and Zhuo M. Genetic enhancement of inflammatory pain by forebrain NR2B overexpression. Nature Neuroscience 4 (2001) 164-169
77. Wei F., Qiu C.S., Kim S.J., Muglia L., Maas J.W., Pineda V.V., Xu H.M., Chen Z.F., Storm D.R., Muglia L.J., and Zhuo M. Genetic elimination of behavioral sensitization in mice lacking calmodulin-stimulated adenylyl cyclases. Neuron 36 (2002) 713-726
78. Wei F., Qiu C.S., Liauw J., Robinson D.A., Ho N., Chatila T., and Zhuo M. Calcium calmodulin-dependent protein kinase IV is required for fear memory. Nature Neuroscience 5 (2002) 573-579
79. Wei F., Xia X.M., Tang J., Ao H., Ko S., Liauw J., Qiu C.S., and Zhuo M. Calmodulin regulates synaptic plasticity in the anterior cingulate cortex and behavioral responses: a microelectroporation study in adult rodents. Journal of Neuroscience 23 (2003) 8402-8409
80. Wozniak D.F., Xiao M., Xu L., Yamada K.A., and Ornitz D.M. Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14. Neurobiology of Disease 26 (2007) 14-26
81. Wu L.J., Toyoda H., Zhao M.G., Lee Y.S., Tang J., Ko S.W., Jia Y.H., Shum F.W., Zerbinatti C.V., Bu G., Wei F., Xu T.L., Muglia L.J., Chen Z.F., Auberson Y.P., Kaang B.K., and Zhuo M. Upregulation of forebrain NMDA NR2B receptors contributes to behavioral sensitization after inflammation. Journal of Neuroscience 25 (2005) 11107-11116
82. Wu L.J., Zhao M.G., Toyoda H., Ko S.W., and Zhuo M. Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex. Journal of Neurophysiology 94 (2005) 1805-1813
83. Wu M.F., Pang Z.P., Zhuo M., and Xu Z.C. Prolonged membrane potential depolarization in cingulate pyramidal cells after digit amputation in adult rats. Molecular Pain 1 (2005) 23
84. Zhao M.G., Toyoda H., Ko S.W., Ding H.K., Wu L.J., and Zhuo M. Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome. Journal of Neuroscience 25 (2005) 7385-7392
85. Zhao M.G., Ko S.W., Wu L.J., Toyoda H., Xu H., Quan J., Li J., Jia Y., Ren M., Xu Z.C., and Zhuo M. Enhanced presynaptic neurotransmitter release in the anterior cingulate cortex of mice with chronic pain. Journal of Neuroscience 26 (2006) 8923-8930
86. Zhuo M. A synaptic model for pain: long-term potentiation in the anterior cingulate cortex. Molecular Cells 23 (2007) 259-271
87. Zhuo, M., 2005. Canadian Association of Neuroscience review: Cellular and synaptic insights into physiological and pathological pain. EJLB-CIHR Michael Smith Chair in Neurosciences and Mental Health lecture. Canadian Journal of Neurological Sciences 32, 27-36.