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Volumn 9, Issue 3, 2003, Pages 179-189

Nitric oxide in inflammatory bowel disease

Author keywords

Animal models; Colitis; Epithelium; Inducible nitric oxide synthase

Indexed keywords

ARGINASE; ARGININE; FREE RADICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; ORNITHINE DECARBOXYLASE; POLYAMINE;

EID: 0038392976     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/00054725-200305000-00006     Document Type: Review
Times cited : (253)

References (126)
  • 1
    • 0029875893 scopus 로고    scopus 로고
    • Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport
    • (Cell Physiol 39)
    • Wilson KT, Vaandrager AB, de Vente J, et al. Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport. Am J Physiol 1996;270(Cell Physiol 39):C832-40.
    • (1996) Am. J. Physiol. , vol.270
    • Wilson, K.T.1    Vaandrager, A.B.2    de Vente, J.3
  • 2
    • 0001509578 scopus 로고
    • Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
    • Stuehr DJ, Marletta MA. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci U S A 1985; 82:7738-42.
    • (1985) Proc. Natl. Acad. Sci. U S A , vol.82 , pp. 7738-7742
    • Stuehr, D.J.1    Marletta, M.A.2
  • 3
    • 0026569273 scopus 로고
    • Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
    • Xie QW, Cho HJ, Calaycay J, et al. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992;256:225-8.
    • (1992) Science , vol.256 , pp. 225-228
    • Xie, Q.W.1    Cho, H.J.2    Calaycay, J.3
  • 4
    • 0027161939 scopus 로고
    • Nitric oxide synthase induction and intestinal epithelial cell viability in rats
    • Tepperman BL, Brown JF, Whittle BJ. Nitric oxide synthase induction and intestinal epithelial cell viability in rats. Am J Physiol 1993;265:G214-8.
    • (1993) Am. J. Physiol. , vol.265
    • Tepperman, B.L.1    Brown, J.F.2    Whittle, B.J.3
  • 5
    • 0028102802 scopus 로고
    • Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells
    • Asano K, Chee CB, Gaston B, et al. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci U S A 1994;91: 10089-93.
    • (1994) Proc. Natl. Acad. Sci. U S A , vol.91 , pp. 10089-10093
    • Asano, K.1    Chee, C.B.2    Gaston, B.3
  • 6
    • 0027364361 scopus 로고
    • Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells
    • Brown JF, Keates AC, Hanson PJ, et al. Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells. Am J Physiol 1993;265:G418-22.
    • (1993) Am. J. Physiol. , vol.265
    • Brown, J.F.1    Keates, A.C.2    Hanson, P.J.3
  • 7
    • 0028071735 scopus 로고
    • Stimulation by carbachol of mucus gel thickness in rat stomach involves nitric oxide
    • Price KJ, Hanson PJ, Whittle BJ. Stimulation by carbachol of mucus gel thickness in rat stomach involves nitric oxide. Eur J Pharmacol 1994;263:199-202.
    • (1994) Eur. J. Pharmacol. , vol.263 , pp. 199-202
    • Price, K.J.1    Hanson, P.J.2    Whittle, B.J.3
  • 8
    • 0027359660 scopus 로고
    • Sodium nitroprusside stimulates anion secretion and inhibits sodium chloride absorption in rat colon
    • Wilson KT, Xie Y, Musch MW, et al. Sodium nitroprusside stimulates anion secretion and inhibits sodium chloride absorption in rat colon. J Pharmacol Exp Ther 1993;266:224-30.
    • (1993) J. Pharmacol. Exp. Ther. , vol.266 , pp. 224-230
    • Wilson, K.T.1    Xie, Y.2    Musch, M.W.3
  • 9
    • 0027259303 scopus 로고
    • Nitric oxide-donating compounds stimulate electrolyte transport in the guinea pig intestine in vitro
    • MacNaughton WK. Nitric oxide-donating compounds stimulate electrolyte transport in the guinea pig intestine in vitro. Life Sci 1993;53:585-93.
    • (1993) Life Sci. , vol.53 , pp. 585-593
    • MacNaughton, W.K.1
  • 10
    • 0027333015 scopus 로고
    • Direct evidence for nitric oxide stimulation of electrolyte secretion in the rat colon
    • Tamai H, Gaginella TS. Direct evidence for nitric oxide stimulation of electrolyte secretion in the rat colon. Free Radic Res Commun 1993;19:229-39.
    • (1993) Free Radic. Res. Commun. , vol.19 , pp. 229-239
    • Tamai, H.1    Gaginella, T.S.2
  • 11
    • 0032444937 scopus 로고    scopus 로고
    • Role of nitric oxide in inflammation-induced suppression of secretion in a mouse model of acute colitis
    • MacNaughton WK, Lowe SS, Cushing K. Role of nitric oxide in inflammation-induced suppression of secretion in a mouse model of acute colitis. Am J Physiol 1998;275:G1353-60.
    • (1998) Am. J. Physiol. , vol.275
    • MacNaughton, W.K.1    Lowe, S.S.2    Cushing, K.3
  • 12
    • 0032945250 scopus 로고    scopus 로고
    • Prolonged colonic epithelial hyporesponsiveness after colitis: Role of inducible nitric oxide synthase
    • Asfaha S, Bell CJ, Wallace JL, et al. Prolonged colonic epithelial hyporesponsiveness after colitis: role of inducible nitric oxide synthase. Am J Physiol 1999;276:G703-10.
    • (1999) Am. J. Physiol. , vol.276
    • Asfaha, S.1    Bell, C.J.2    Wallace, J.L.3
  • 13
    • 0032538095 scopus 로고    scopus 로고
    • Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: Role of superoxide radical, hydroxyl radical, and peroxynitrite
    • 1425
    • Menconi MJ, Unno N, Smith M, et al. Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite. Biochim Biophys Acta 1998;1425:189-203.
    • (1998) Biochim. Biophys. Acta , pp. 189-203
    • Menconi, M.J.1    Unno, N.2    Smith, M.3
  • 14
    • 0024553788 scopus 로고
    • Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers
    • Madara JL, Stafford J. Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers. J Clin Invest 1989;83:724-7.
    • (1989) J. Clin. Invest. , vol.83 , pp. 724-727
    • Madara, J.L.1    Stafford, J.2
  • 15
    • 0035053279 scopus 로고    scopus 로고
    • Inhibition of Na+,K+-ATPase by interferon gamma downregulates intestinal epithelial transport and barrier function
    • Sugi K, Musch MW, Field M, et al. Inhibition of Na+,K+-ATPase by interferon gamma downregulates intestinal epithelial transport and barrier function. Gastroenterology 2001;120:1393-403.
    • (2001) Gastroenterology , vol.120 , pp. 1393-1403
    • Sugi, K.1    Musch, M.W.2    Field, M.3
  • 16
    • 0032734162 scopus 로고    scopus 로고
    • Cytokine-induced intestinal epithelial hyperpermeability: Role of nitric oxide
    • Chavez AM, Menconi MJ, Hodin RA, et al. Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide. Crit Care Med 1999;27:2246-51.
    • (1999) Crit. Care Med. , vol.27 , pp. 2246-2251
    • Chavez, A.M.1    Menconi, M.J.2    Hodin, R.A.3
  • 17
    • 0024850301 scopus 로고
    • The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation
    • Pique JM, Whittle BJ, Esplugues JV. The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation. Eur J Pharmacol 1989;174:293-6.
    • (1989) Eur. J. Pharmacol. , vol.174 , pp. 293-296
    • Pique, J.M.1    Whittle, B.J.2    Esplugues, J.V.3
  • 18
    • 0022483272 scopus 로고
    • Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons
    • Holzer P, Sametz W. Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons. Gastroenterology 1986;91:975-81.
    • (1986) Gastroenterology , vol.91 , pp. 975-981
    • Holzer, P.1    Sametz, W.2
  • 19
    • 0026537015 scopus 로고
    • Participation of endothelium-derived nitric oxide but not prostacyclin in the gastric mucosal hyperaemia due to acid back-diffusion
    • Lippe IT, Holzer P. Participation of endothelium-derived nitric oxide but not prostacyclin in the gastric mucosal hyperaemia due to acid back-diffusion. Br J Pharmacol 1992;105:708-14.
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 708-714
    • Lippe, I.T.1    Holzer, P.2
  • 20
    • 0025239572 scopus 로고
    • Afferent nerve-mediated protection against deep mucosal damage in the rat stomach
    • Holzer P, Pabst MA, Lippe IT, et al. Afferent nerve-mediated protection against deep mucosal damage in the rat stomach. Gastroenterology 1990;98:838-48.
    • (1990) Gastroenterology , vol.98 , pp. 838-848
    • Holzer, P.1    Pabst, M.A.2    Lippe, I.T.3
  • 21
    • 0030795606 scopus 로고    scopus 로고
    • Nitric oxide inhibits neutrophil beta 2 integrin function by inhibiting membrane-associated cyclic GMP synthesis
    • Banick PD, Chen Q, Xu YA, et al. Nitric oxide inhibits neutrophil beta 2 integrin function by inhibiting membrane-associated cyclic GMP synthesis. J Cell Physiol 1997;172:12-24.
    • (1997) J. Cell Physiol. , vol.172 , pp. 12-24
    • Banick, P.D.1    Chen, Q.2    Xu, Y.A.3
  • 22
    • 0028128957 scopus 로고
    • Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation
    • Davenpeck KL, Gauthier TW, Lefer AM. Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation. Gastroenterology 1994;107: 1050-8.
    • (1994) Gastroenterology , vol.107 , pp. 1050-1058
    • Davenpeck, K.L.1    Gauthier, T.W.2    Lefer, A.M.3
  • 24
    • 0032171599 scopus 로고    scopus 로고
    • Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: Relevance to ischemic heart disease
    • Grisham MB, Granger DN, Lefer DJ. Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease. Free Radic Biol Med 1998;25:404-33.
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 404-433
    • Grisham, M.B.1    Granger, D.N.2    Lefer, D.J.3
  • 25
    • 0028083609 scopus 로고
    • Nitric oxide synthesis inhibition increases epithelial permeability via mast cells
    • Kanwar S, Wallace JL, Befus D, et al. Nitric oxide synthesis inhibition increases epithelial permeability via mast cells. Am J Physiol 1994;266:G222-9.
    • (1994) Am. J. Physiol. , vol.266
    • Kanwar, S.1    Wallace, J.L.2    Befus, D.3
  • 26
    • 0342890235 scopus 로고    scopus 로고
    • Interleukin-1 production by mouse macrophages is regulated in a feedback fashion by nitric oxide
    • Obermeier F, Gross V, Scholmerich J, et al. Interleukin-1 production by mouse macrophages is regulated in a feedback fashion by nitric oxide. J Leukoc Biol 1999;66:829-36.
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 829-836
    • Obermeier, F.1    Gross, V.2    Scholmerich, J.3
  • 27
    • 0031795118 scopus 로고    scopus 로고
    • Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages
    • Huang FP, Niedbala W, Wei XQ, et al. Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. Eur J Immunol 1998;28:4062-70.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4062-4070
    • Huang, F.P.1    Niedbala, W.2    Wei, X.Q.3
  • 28
    • 0037097533 scopus 로고    scopus 로고
    • Cutting edge: Urease release by Helicobacter pylori stimulates macrophage inducible nitric oxide synthase
    • Gobert AP, Mersey BD, Cheng Y, et al. Cutting edge: urease release by Helicobacter pylori stimulates macrophage inducible nitric oxide synthase. J Immunol 2002;168:6002-6.
    • (2002) J. Immunol. , vol.168 , pp. 6002-6006
    • Gobert, A.P.1    Mersey, B.D.2    Cheng, Y.3
  • 29
    • 0036570172 scopus 로고    scopus 로고
    • Helicobacter pylori induces macrophage apoptosis by activation of arginase II
    • Gobert AP, Cheng Y, Wang JY, et al. Helicobacter pylori induces macrophage apoptosis by activation of arginase II. J Immunol 2002;168:4692-700.
    • (2002) J. Immunol. , vol.168 , pp. 4692-4700
    • Gobert, A.P.1    Cheng, Y.2    Wang, J.Y.3
  • 30
    • 0029852664 scopus 로고    scopus 로고
    • Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line
    • Wilson KT, Ramanujam KS, Mobley HLT, et al. Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. Gastroenterology 1996; 111:1524-33.
    • (1996) Gastroenterology , vol.111 , pp. 1524-1533
    • Wilson, K.T.1    Ramanujam, K.S.2    Mobley, H.L.T.3
  • 31
    • 0034646670 scopus 로고    scopus 로고
    • Reactive nitrogen and oxygen species attenuate interleukin-8-induced neutrophil chemotactic activity in vitro
    • Sato E, Simpson KL, Grisham MB, et al. Reactive nitrogen and oxygen species attenuate interleukin-8-induced neutrophil chemotactic activity in vitro. J Biol Chem 2000;275:10826-30.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10826-10830
    • Sato, E.1    Simpson, K.L.2    Grisham, M.B.3
  • 32
    • 0032888715 scopus 로고    scopus 로고
    • Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro
    • Sato E, Simpson KL, Grisham MB, et al. Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro. Am J Physiol 1999;277:L543-9.
    • (1999) Am. J. Physiol. , vol.277
    • Sato, E.1    Simpson, K.L.2    Grisham, M.B.3
  • 33
    • 0033777196 scopus 로고    scopus 로고
    • Nitric oxide induces chemotaxis of neutrophil-like HL-60 cells and translocation of cofilin to plasma membranes
    • Adachi R, Matsui S, Kinoshita M, et al. Nitric oxide induces chemotaxis of neutrophil-like HL-60 cells and translocation of cofilin to plasma membranes. Int J Immunopharmacol 2000;22: 855-64.
    • (2000) Int. J. Immunopharmacol. , vol.22 , pp. 855-864
    • Adachi, R.1    Matsui, S.2    Kinoshita, M.3
  • 34
    • 0028851926 scopus 로고
    • Relaxin activates the L-arginine-nitric oxide pathway in human breast cancer cells
    • Bani D, Masini E, Bello MG, et al. Relaxin activates the L-arginine-nitric oxide pathway in human breast cancer cells. Cancer Res 1995;55:5272-5.
    • (1995) Cancer Res. , vol.55 , pp. 5272-5275
    • Bani, D.1    Masini, E.2    Bello, M.G.3
  • 36
    • 0028125013 scopus 로고
    • p53 expression in nitric oxide-induced apoptosis
    • Messmer UK, Ankarcrona M, Nicotera P, et al. p53 expression in nitric oxide-induced apoptosis. FEBS Lett 1994;355:23-6.
    • (1994) FEBS Lett. , vol.355 , pp. 23-26
    • Messmer, U.K.1    Ankarcrona, M.2    Nicotera, P.3
  • 37
    • 0025730414 scopus 로고
    • Peroxynitrite oxidation of sulfhydryls: The cytotoxic potential of superoxide and nitric oxide
    • Radi R, Beckman JS, Bush KM, et al. Peroxynitrite oxidation of sulfhydryls: the cytotoxic potential of superoxide and nitric oxide. J Biol Chem 1991;266:4244-50.
    • (1991) J. Biol. Chem. , vol.266 , pp. 4244-4250
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3
  • 38
    • 0028842112 scopus 로고
    • Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells: A possible mechanism of neovascularization in atherosclerotic plaques
    • Fukuo K, Inoue T, Morimoto S, et al. Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells: a possible mechanism of neovascularization in atherosclerotic plaques. J Clin Invest 1995;95: 669-76.
    • (1995) J. Clin. Invest. , vol.95 , pp. 669-676
    • Fukuo, K.1    Inoue, T.2    Morimoto, S.3
  • 39
    • 0026321495 scopus 로고
    • DNA deaminating ability and genotoxicity of nitric oxide and its progenitors
    • Wink DA, Kasprzak KS, Maragos CM, et al. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 1991;254:1001-3.
    • (1991) Science , vol.254 , pp. 1001-1003
    • Wink, D.A.1    Kasprzak, K.S.2    Maragos, C.M.3
  • 40
    • 0026522884 scopus 로고
    • DNA damage and mutation in human cells exposed to nitric oxide in vitro
    • Nguyen T, Brunson D, Crespi CL, et al. DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proc Natl Acad Sci U S A 1992;89:3030-4.
    • (1992) Proc. Natl. Acad. Sci. U S A , vol.89 , pp. 3030-3034
    • Nguyen, T.1    Brunson, D.2    Crespi, C.L.3
  • 41
    • 0006812769 scopus 로고
    • Potential genotoxicity of chronically elevated nitric oxide: A review
    • Liu RH, Hotchkiss JH. Potential genotoxicity of chronically elevated nitric oxide: a review. Mutat Res 1995;339:73-89.
    • (1995) Mutat. Res. , vol.339 , pp. 73-89
    • Liu, R.H.1    Hotchkiss, J.H.2
  • 42
    • 0028332056 scopus 로고
    • Nitric oxide synthase isozymes: Characterization, purification, molecular cloning, and functions
    • Forstermann U, Closs EI, Pollock JS, et al. Nitric oxide synthase isozymes: characterization, purification, molecular cloning, and functions. Hypertension 1994;23:1121-31.
    • (1994) Hypertension , vol.23 , pp. 1121-1131
    • Forstermann, U.1    Closs, E.I.2    Pollock, J.S.3
  • 43
    • 0029029834 scopus 로고
    • Nitric oxide mediates mitochondrial dysfunction in hepatoma cells induced by non-activated Kupffer cells: Evidence implicating ICAM-1-dependent process
    • Kurose I, Ebinuma H, Higuchi H, et al. Nitric oxide mediates mitochondrial dysfunction in hepatoma cells induced by non-activated Kupffer cells: evidence implicating ICAM-1-dependent process. J Gastroenterol Hepatol 1995;10(suppl 1):S68-71.
    • (1995) J. Gastroenterol. Hepatol. , vol.10 , Issue.SUPPL. 1
    • Kurose, I.1    Ebinuma, H.2    Higuchi, H.3
  • 44
    • 0027397892 scopus 로고
    • Increased nitric oxide synthesis in ulcerative colitis
    • Middleton SJ, Shorthouse M, Hunter JO. Increased nitric oxide synthesis in ulcerative colitis. Lancet 1993;341:465-6.
    • (1993) Lancet , vol.341 , pp. 465-466
    • Middleton, S.J.1    Shorthouse, M.2    Hunter, J.O.3
  • 45
    • 0027255461 scopus 로고
    • Nitric oxide synthase activity in ulcerative colitis and Crohn's disease
    • Boughton-Smith NK, Evans SM, Hawkey CJ, et al. Nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Lancet 1993;342:338-40.
    • (1993) Lancet , vol.342 , pp. 338-340
    • Boughton-Smith, N.K.1    Evans, S.M.2    Hawkey, C.J.3
  • 46
    • 0028998288 scopus 로고
    • Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease
    • Rachmilewitz D, Stamler JS, Bachwich D, et al. Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Gut 1995;36:718-23.
    • (1995) Gut , vol.36 , pp. 718-723
    • Rachmilewitz, D.1    Stamler, J.S.2    Bachwich, D.3
  • 47
    • 0028081788 scopus 로고
    • Greatly increased luminal nitric oxide in ulcerative colitis
    • Lundberg JO, Hellstrom PM, Lundberg JM, et al. Greatly increased luminal nitric oxide in ulcerative colitis. Lancet 1994; 344:1673-4.
    • (1994) Lancet , vol.344 , pp. 1673-1674
    • Lundberg, J.O.1    Hellstrom, P.M.2    Lundberg, J.M.3
  • 48
    • 0034875748 scopus 로고    scopus 로고
    • Rectal nitric oxide assessment in children with Crohn disease and ulcerative colitis: Indicator of ileocaecal and colorectal affection
    • Ljung T, Herulf M, Beijer E, et al. Rectal nitric oxide assessment in children with Crohn disease and ulcerative colitis: indicator of ileocaecal and colorectal affection. Scand J Gastroenterol 2001; 36:1073-6.
    • (2001) Scand. J. Gastroenterol. , vol.36 , pp. 1073-1076
    • Ljung, T.1    Herulf, M.2    Beijer, E.3
  • 49
    • 0036239353 scopus 로고    scopus 로고
    • Increased rectal nitric oxide in children with active inflammatory bowel disease
    • Ljung T, Beijer E, Herulf M, et al. Increased rectal nitric oxide in children with active inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2002;34:302-6.
    • (2002) J. Pediatr. Gastroenterol. Nutr. , vol.34 , pp. 302-306
    • Ljung, T.1    Beijer, E.2    Herulf, M.3
  • 50
    • 0036157878 scopus 로고    scopus 로고
    • Colonic production of nitric oxide gas in ulcerative colitis, collagenous colitis and un-inflamed bowel
    • Perner A, Nordgaard I, Matzen P, et al. Colonic production of nitric oxide gas in ulcerative colitis, collagenous colitis and un-inflamed bowel. Scand J Gastroenterol 2002;37:183-8.
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 183-188
    • Perner, A.1    Nordgaard, I.2    Matzen, P.3
  • 51
    • 0031955490 scopus 로고    scopus 로고
    • Greatly increased mucosal nitric oxide in ulcerative colitis determined in situ by a novel nitric oxide-selective micro-electrode
    • Iwashita E. Greatly increased mucosal nitric oxide in ulcerative colitis determined in situ by a novel nitric oxide-selective micro-electrode. J Gastroenterol Hepatol 1998;13:391-5.
    • (1998) J. Gastroenterol. Hepatol. , vol.13 , pp. 391-395
    • Iwashita, E.1
  • 52
    • 0034983157 scopus 로고    scopus 로고
    • Increased urinary nitrite, a marker of nitric oxide, in active inflammatory bowel disease
    • Goggins MG, Shah SA, Goh J, et al. Increased urinary nitrite, a marker of nitric oxide, in active inflammatory bowel disease. Mediators Inflamm 2001;10:69-73.
    • (2001) Mediators Inflamm. , vol.10 , pp. 69-73
    • Goggins, M.G.1    Shah, S.A.2    Goh, J.3
  • 53
    • 0029848602 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase in ulcerative colitis
    • Godkin AJ, De Belder AJ, Villa L, et al. Expression of nitric oxide synthase in ulcerative colitis. Eur J Clin Invest 1996;26: 867-72.
    • (1996) Eur. J. Clin. Invest. , vol.26 , pp. 867-872
    • Godkin, A.J.1    De Belder, A.J.2    Villa, L.3
  • 54
    • 0031782826 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase in inflammatory bowel disease is not affected by corticosteroid treatment
    • Leonard N, Bishop AE, Polak JM, et al. Expression of nitric oxide synthase in inflammatory bowel disease is not affected by corticosteroid treatment. J Clin Pathol 1998;51:750-3.
    • (1998) J. Clin. Pathol. , vol.51 , pp. 750-753
    • Leonard, N.1    Bishop, A.E.2    Polak, J.M.3
  • 55
    • 0036000211 scopus 로고    scopus 로고
    • Increased expression of inducible nitric oxide synthase in circulating monocytes from patients with active inflammatory bowel disease
    • Dijkstra G, Zandvoort AJ, Kobold AC, et al. Increased expression of inducible nitric oxide synthase in circulating monocytes from patients with active inflammatory bowel disease. Scand J Gastroenterol 2002;37:546-54.
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 546-554
    • Dijkstra, G.1    Zandvoort, A.J.2    Kobold, A.C.3
  • 56
    • 0029816226 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease
    • Singer II, Kawka DW, Scott S, et al. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 1996;111: 871-85.
    • (1996) Gastroenterology , vol.111 , pp. 871-885
    • Singer, I.I.1    Kawka, D.W.2    Scott, S.3
  • 57
    • 0035065028 scopus 로고    scopus 로고
    • The physiological expression of inducible nitric oxide synthase (iNOS) in the human colon
    • Roberts PJ, Riley GP, Morgan K, et al. The physiological expression of inducible nitric oxide synthase (iNOS) in the human colon. J Clin Pathol 2001;54:293-7.
    • (2001) J. Clin. Pathol. , vol.54 , pp. 293-297
    • Roberts, P.J.1    Riley, G.P.2    Morgan, K.3
  • 58
    • 0035120609 scopus 로고    scopus 로고
    • Changes in distribution of three isoforms of nitric oxide synthase in ulcerative colitis
    • Vento P, Kiviluoto T, Jarvinen HJ, et al. Changes in distribution of three isoforms of nitric oxide synthase in ulcerative colitis. Scand J Gastroenterol 2001;36:180-9.
    • (2001) Scand. J. Gastroenterol. , vol.36 , pp. 180-189
    • Vento, P.1    Kiviluoto, T.2    Jarvinen, H.J.3
  • 59
    • 0031839897 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase activity in human colon epithelial cells: Modulation by T lymphocyte derived cytokines
    • Kolios G, Rooney N, Murphy CT, et al. Expression of inducible nitric oxide synthase activity in human colon epithelial cells: modulation by T lymphocyte derived cytokines. Gut 1998;43: 56-63.
    • (1998) Gut , vol.43 , pp. 56-63
    • Kolios, G.1    Rooney, N.2    Murphy, C.T.3
  • 60
    • 7144253803 scopus 로고    scopus 로고
    • Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis
    • Kimura H, Hokari R, Miura S, et al. Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis. Gut 1998;42:180-7.
    • (1998) Gut , vol.42 , pp. 180-187
    • Kimura, H.1    Hokari, R.2    Miura, S.3
  • 61
    • 0032034113 scopus 로고    scopus 로고
    • Direct determination of colonic nitric oxide level: A sensitive marker of disease activity in ulcerative colitis
    • Rachmilewitz D, Eliakim R, Ackerman Z, et al. Direct determination of colonic nitric oxide level: a sensitive marker of disease activity in ulcerative colitis. Am J Gastroenterol 1998;93:409-12.
    • (1998) Am. J. Gastroenterol. , vol.93 , pp. 409-412
    • Rachmilewitz, D.1    Eliakim, R.2    Ackerman, Z.3
  • 62
    • 0034777650 scopus 로고    scopus 로고
    • Expression of inducible and endothelial nitric oxide synthases in pouchitis
    • Vento P, Kiviluoto T, Jarvinen HJ, et al. Expression of inducible and endothelial nitric oxide synthases in pouchitis. Inflamm Bowel Dis 2001;7:120-7.
    • (2001) Inflamm. Bowel Dis. , vol.7 , pp. 120-127
    • Vento, P.1    Kiviluoto, T.2    Jarvinen, H.J.3
  • 63
    • 0028960570 scopus 로고
    • Are serum concentrations of nitric oxide metabolites useful for predicting the clinical outcome of severe ulcerative colitis?
    • Rees DC, Satsangi J, Cornelissen PL, et al. Are serum concentrations of nitric oxide metabolites useful for predicting the clinical outcome of severe ulcerative colitis? Eur J Gastroenterol Hepatol 1995;7:227-30.
    • (1995) Eur. J. Gastroenterol. Hepatol. , vol.7 , pp. 227-230
    • Rees, D.C.1    Satsangi, J.2    Cornelissen, P.L.3
  • 64
    • 0036657419 scopus 로고    scopus 로고
    • Activity related increase of exhaled nitric oxide in Crohn's disease and ulcerative colitis: A manifestation of systemic involvement?
    • Koek GH, Verleden GM, Evenepoel P, et al. Activity related increase of exhaled nitric oxide in Crohn's disease and ulcerative colitis: a manifestation of systemic involvement? Respir Med 2002;96:530-5.
    • (2002) Respir. Med. , vol.96 , pp. 530-535
    • Koek, G.H.1    Verleden, G.M.2    Evenepoel, P.3
  • 65
    • 0034031857 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase activity in colon biopsies from inflammatory areas: Correlation with inflammation intensity in patients with ulcerative colitis but not with Crohn's disease
    • Guihot G, Guimbaud R, Bertrand V, et al. Inducible nitric oxide synthase activity in colon biopsies from inflammatory areas: correlation with inflammation intensity in patients with ulcerative colitis but not with Crohn's disease. Amino Acids 2000;18: 229-37.
    • (2000) Amino Acids , vol.18 , pp. 229-237
    • Guihot, G.1    Guimbaud, R.2    Bertrand, V.3
  • 66
    • 8244235129 scopus 로고    scopus 로고
    • Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease
    • Kimura H, Miura S, Shigematsu T, et al. Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease. Dig Dis Sci 1997;42:1047-54.
    • (1997) Dig. Dis. Sci. , vol.42 , pp. 1047-1054
    • Kimura, H.1    Miura, S.2    Shigematsu, T.3
  • 67
    • 0028879567 scopus 로고
    • Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis
    • Miller MJS, Thompson JH, Zhang X-J, et al. Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis. Gastroenterology 1995;109:1475-83.
    • (1995) Gastroenterology , vol.109 , pp. 1475-1483
    • Miller, M.J.S.1    Thompson, J.H.2    Zhang, X.-J.3
  • 68
    • 0027138788 scopus 로고
    • Peroxynitrite-induced rat colitis: A new model of colonic inflammation
    • Rachmilewitz D, Stamler JS, Karmeli F, et al. Peroxynitrite-induced rat colitis: a new model of colonic inflammation. Gastroenterology 1993;105:1681-8.
    • (1993) Gastroenterology , vol.105 , pp. 1681-1688
    • Rachmilewitz, D.1    Stamler, J.S.2    Karmeli, F.3
  • 69
    • 0028941787 scopus 로고
    • Potential role of nitric oxide in a model of chronic colitis in rhesus macaques
    • Ribbons KA, Zhang XJ, Thompson JH, et al. Potential role of nitric oxide in a model of chronic colitis in rhesus macaques. Gastroenterology 1995;108:705-11.
    • (1995) Gastroenterology , vol.108 , pp. 705-711
    • Ribbons, K.A.1    Zhang, X.J.2    Thompson, J.H.3
  • 71
    • 0028072869 scopus 로고
    • Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis
    • Grisham MB, Specian RD, Zimmerman TE. Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis. J Pharmacol Exp Ther 1994;271:1114-21.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1114-1121
    • Grisham, M.B.1    Specian, R.D.2    Zimmerman, T.E.3
  • 72
    • 0029050740 scopus 로고
    • Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase
    • Rachmilewitz D, Karmeli F, Okon E. Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase. Gastroenterology 1995;109:98-106.
    • (1995) Gastroenterology , vol.109 , pp. 98-106
    • Rachmilewitz, D.1    Karmeli, F.2    Okon, E.3
  • 73
    • 0029115715 scopus 로고
    • Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity
    • Rachmilewitz D, Karmeli F, Okon E, et al. Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 1995;37:247-55.
    • (1995) Gut , vol.37 , pp. 247-255
    • Rachmilewitz, D.1    Karmeli, F.2    Okon, E.3
  • 74
    • 0029071036 scopus 로고
    • Spontaneous intestinal inflammation and nitric oxide metabolism in HLA-B27 transgenic rats
    • Aiko S, Grisham MB. Spontaneous intestinal inflammation and nitric oxide metabolism in HLA-B27 transgenic rats. Gastroenterology 1995;109:142-50.
    • (1995) Gastroenterology , vol.109 , pp. 142-150
    • Aiko, S.1    Grisham, M.B.2
  • 75
    • 0028928065 scopus 로고
    • The selective beneficial effects of nitric oxide inhibition in experimental colitis
    • Hogaboam CM, Jacobson K, Collins SM, et al. The selective beneficial effects of nitric oxide inhibition in experimental colitis. Am J Physiol 1995;268:G673-84.
    • (1995) Am. J. Physiol. , vol.268
    • Hogaboam, C.M.1    Jacobson, K.2    Collins, S.M.3
  • 76
    • 0030663799 scopus 로고    scopus 로고
    • Time-dependent actions of nitric oxide synthase inhibition on colonic inflammation induced by trinitrobenzene sulphonic acid in rats
    • Kiss J, Lamarque D, Delchier JC, et al. Time-dependent actions of nitric oxide synthase inhibition on colonic inflammation induced by trinitrobenzene sulphonic acid in rats. Eur J Pharmacol 1997;336:219-24.
    • (1997) Eur. J. Pharmacol. , vol.336 , pp. 219-224
    • Kiss, J.1    Lamarque, D.2    Delchier, J.C.3
  • 77
    • 0034893711 scopus 로고    scopus 로고
    • Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(aminomethyl)benzyl]acetamidine
    • Kankuri E, Vaali K, Knowles RG, et al. Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(aminomethyl)benzyl]acetamidine. J Pharmacol Exp Ther 2001;298:1128-32.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 1128-1132
    • Kankuri, E.1    Vaali, K.2    Knowles, R.G.3
  • 78
    • 0035876368 scopus 로고    scopus 로고
    • N-(3-(amino-methyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats
    • Menchen LA, Colon AL, Moro MA, et al. N-(3-(amino-methyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats. Life Sci 2001;69:479-91.
    • (2001) Life Sci. , vol.69 , pp. 479-491
    • Menchen, L.A.1    Colon, A.L.2    Moro, M.A.3
  • 79
    • 0035104805 scopus 로고    scopus 로고
    • Differing effects of two nitric oxide synthase inhibitors on experimental colitis
    • Yamaguchi T, Yoshida N, Ichiishi E, et al. Differing effects of two nitric oxide synthase inhibitors on experimental colitis. Hepatogastroenterology 2001;48:118-22.
    • (2001) Hepatogastroenterology , vol.48 , pp. 118-122
    • Yamaguchi, T.1    Yoshida, N.2    Ichiishi, E.3
  • 80
    • 0032738480 scopus 로고    scopus 로고
    • Aminoguanidine has both an antiinflammatory effect on experimental colitis and a proliferative effect on colonic mucosal cells
    • Nakamura H, Tsukada H, Oya M, et al. Aminoguanidine has both an antiinflammatory effect on experimental colitis and a proliferative effect on colonic mucosal cells. Scand J Gastroenterol 1999;34:1117-22.
    • (1999) Scand. J. Gastroenterol. , vol.34 , pp. 1117-1122
    • Nakamura, H.1    Tsukada, H.2    Oya, M.3
  • 81
    • 0032941175 scopus 로고    scopus 로고
    • Interferon-gamma (IFN-gamma)- and tumor necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice
    • Obermeier F, Kojouharoff G, Hans W, et al. Interferon-gamma (IFN-gamma)- and tumor necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. Clin Exp Immunol 1999;116: 238-45.
    • (1999) Clin. Exp. Immunol. , vol.116 , pp. 238-245
    • Obermeier, F.1    Kojouharoff, G.2    Hans, W.3
  • 82
    • 0032253673 scopus 로고    scopus 로고
    • Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxy-nitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats
    • Zingarelli B, Cuzzocrea S, Szabo C, et al. Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxy-nitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats. J Pharmacol Exp Ther 1998;287: 1048-55.
    • (1998) J. Pharmacol. Exp. Ther. , vol.287 , pp. 1048-1055
    • Zingarelli, B.1    Cuzzocrea, S.2    Szabo, C.3
  • 83
    • 0034822239 scopus 로고    scopus 로고
    • Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation
    • Asfaha S, MacNaughton WK, Appleyard CB, et al. Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 2001;281:G635-44.
    • (2001) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.281
    • Asfaha, S.1    MacNaughton, W.K.2    Appleyard, C.B.3
  • 84
    • 0035008079 scopus 로고    scopus 로고
    • Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production
    • Yue G, Lai PS, Yin K, et al. Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production. J Pharmacol Exp Ther 2001:297:915-25.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 915-925
    • Yue, G.1    Lai, P.S.2    Yin, K.3
  • 85
    • 0035175169 scopus 로고    scopus 로고
    • Role of nitric oxide synthase inhibitor in experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats
    • Hosoi T, Goto H, Arisawa T, et al. Role of nitric oxide synthase inhibitor in experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats. Clin Exp Pharmacol Physiol 2001;28: 9-12.
    • (2001) Clin. Exp. Pharmacol. Physiol. , vol.28 , pp. 9-12
    • Hosoi, T.1    Goto, H.2    Arisawa, T.3
  • 86
    • 0030899297 scopus 로고    scopus 로고
    • The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey
    • Ribbons KA, Currie MG, Connor JR, et al. The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey. J Pharmacol Exp Ther 1997;280:1008-15.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 1008-1015
    • Ribbons, K.A.1    Currie, M.G.2    Connor, J.R.3
  • 87
    • 0035057241 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis
    • Dikopoulos N, Nussler AK, Liptay S, et al. Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis. Eur J Clin Invest 2001;31: 234-9.
    • (2001) Eur. J. Clin. Invest. , vol.31 , pp. 234-239
    • Dikopoulos, N.1    Nussler, A.K.2    Liptay, S.3
  • 88
    • 0034127618 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in dextran sulphate sodium-induced colitis
    • Yoshida Y, Iwai A, Itoh K, et al. Role of inducible nitric oxide synthase in dextran sulphate sodium-induced colitis. Aliment Pharmacol Ther 2000;14(suppl 1):26-32.
    • (2000) Aliment. Pharmacol. Ther. , vol.14 , Issue.SUPPL. 1 , pp. 26-32
    • Yoshida, Y.1    Iwai, A.2    Itoh, K.3
  • 89
    • 0033811660 scopus 로고    scopus 로고
    • Oral administration of inducible nitric oxide synthase inhibitors reduces nitric oxide synthesis but has no effect on the severity of experimental colitis
    • Armstrong AM, Campbell GR, Gannon C, et al. Oral administration of inducible nitric oxide synthase inhibitors reduces nitric oxide synthesis but has no effect on the severity of experimental colitis. Scand J Gastroenterol 2000;35:832-8.
    • (2000) Scand. J. Gastroenterol. , vol.35 , pp. 832-838
    • Armstrong, A.M.1    Campbell, G.R.2    Gannon, C.3
  • 90
    • 0036096738 scopus 로고    scopus 로고
    • Nitric oxide supplementation ameliorates dextran sulfate sodium-induced colitis in mice
    • Salas A, Gironella M, Soriano A, et al. Nitric oxide supplementation ameliorates dextran sulfate sodium-induced colitis in mice. Lab Invest 2002;82:597-607.
    • (2002) Lab. Invest. , vol.82 , pp. 597-607
    • Salas, A.1    Gironella, M.2    Soriano, A.3
  • 91
    • 0037180496 scopus 로고    scopus 로고
    • NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice
    • Fiorucci S, Antonelli E, Distrutti E, et al. NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Proc Natl Acad Sci U S A 2002;99:15770-5.
    • (2002) Proc. Natl. Acad. Sci. U S A , vol.99 , pp. 15770-15775
    • Fiorucci, S.1    Antonelli, E.2    Distrutti, E.3
  • 92
    • 0031041841 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation
    • McCafferty DM, Mudgett JS, Swain MG, et al. Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation. Gastroenterology 1997;112:1022-7.
    • (1997) Gastroenterology , vol.112 , pp. 1022-1027
    • McCafferty, D.M.1    Mudgett, J.S.2    Swain, M.G.3
  • 93
    • 0032712861 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice
    • McCafferty DM, Miampamba M, Sihota E, et al. Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice. Gut 1999;45:864-73.
    • (1999) Gut , vol.45 , pp. 864-873
    • McCafferty, D.M.1    Miampamba, M.2    Sihota, E.3
  • 95
    • 0035879845 scopus 로고    scopus 로고
    • Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis
    • Hokari R, Kato S, Matsuzaki K, et al. Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis. Free Radic Biol Med 2001;31:153-63.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 153-163
    • Hokari, R.1    Kato, S.2    Matsuzaki, K.3
  • 96
    • 0035158627 scopus 로고    scopus 로고
    • Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: Divergent roles of superoxide and nitric oxide
    • Krieglstein CF, Cerwinka WH, Laroux FS, et al. Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide. J Exp Med 2001;194:1207-18.
    • (2001) J. Exp. Med. , vol.194 , pp. 1207-1218
    • Krieglstein, C.F.1    Cerwinka, W.H.2    Laroux, F.S.3
  • 97
    • 0031659995 scopus 로고    scopus 로고
    • iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion
    • Binion DG, Fu S, Ramanujam KS, et al. iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion. Am J Physiol 1998;275:G592-603.
    • (1998) Am. J. Physiol. , vol.275
    • Binion, D.G.1    Fu, S.2    Ramanujam, K.S.3
  • 98
    • 0034333259 scopus 로고    scopus 로고
    • Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion
    • Binion DG, Rafiee P, Ramanujam KS, et al. Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. Free Radic Biol Med 2000;29:881-8.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 881-888
    • Binion, D.G.1    Rafiee, P.2    Ramanujam, K.S.3
  • 99
    • 18544389096 scopus 로고    scopus 로고
    • Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS: Paradoxical proinflammatory effect on the microvascular endothelium
    • Rafiee P, Johnson CP, Li MS, et al. Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS: paradoxical proinflammatory effect on the microvascular endothelium. J Biol Chem 2002;277:35605-15.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35605-35615
    • Rafiee, P.1    Johnson, C.P.2    Li, M.S.3
  • 100
  • 102
    • 0035099627 scopus 로고    scopus 로고
    • Polyamines in cell growth and cell death: Molecular mechanisms and therapeutic applications
    • Thomas T, Thomas TJ. Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 2001;58:244-58.
    • (2001) Cell Mol. Life Sci. , vol.58 , pp. 244-258
    • Thomas, T.1    Thomas, T.J.2
  • 104
    • 0035026932 scopus 로고    scopus 로고
    • NF-κB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells
    • Li L, Rao JN, Bass BL, et al. NF-κB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2001;280:G992-1004.
    • (2001) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.280
    • Li, L.1    Rao, J.N.2    Bass, B.L.3
  • 105
    • 0030965838 scopus 로고    scopus 로고
    • Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: A counterregulatory mechanism that restrains the immune response
    • Zhang M, Caragine T, Wang H, et al. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response. J Exp Med 1997;185:1759-68.
    • (1997) J. Exp. Med. , vol.185 , pp. 1759-1768
    • Zhang, M.1    Caragine, T.2    Wang, H.3
  • 106
    • 0034242623 scopus 로고    scopus 로고
    • Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma
    • Hasko G, Kuhel DG, Marton A, et al. Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma. Shock 2000;14:144-9.
    • (2000) Shock , vol.14 , pp. 144-149
    • Hasko, G.1    Kuhel, D.G.2    Marton, A.3
  • 107
    • 0025340505 scopus 로고
    • Delineation between T and B suppressive molecules from human seminal plasma: II. Spermine is the major suppressor of T-lymphocytes in vitro
    • Quan CP, Roux C, Pillot J, et al. Delineation between T and B suppressive molecules from human seminal plasma: II. Spermine is the major suppressor of T-lymphocytes in vitro. Am J Reprod Immunol 1990;22:64-9.
    • (1990) Am. J. Reprod. Immunol. , vol.22 , pp. 64-69
    • Quan, C.P.1    Roux, C.2    Pillot, J.3
  • 108
    • 0021798350 scopus 로고
    • Inhibition of human neutrophil locomotion by the polyamine oxidase-polyamine system
    • Ferrante A. Inhibition of human neutrophil locomotion by the polyamine oxidase-polyamine system. Immunology 1985;54: 785-90.
    • (1985) Immunology , vol.54 , pp. 785-790
    • Ferrante, A.1
  • 110
    • 0343554767 scopus 로고    scopus 로고
    • Human type II arginase: Sequence analysis and tissue-specific expression
    • Morris SM Jr, Bhamidipati D, Kepka-Lenhart D. Human type II arginase: sequence analysis and tissue-specific expression. Gene 1997;193:157-61.
    • (1997) Gene , vol.193 , pp. 157-161
    • Morris S.M., Jr.1    Bhamidipati, D.2    Kepka-Lenhart, D.3
  • 111
    • 0343621540 scopus 로고    scopus 로고
    • Induction of arginase II in human caco-2 tumor cells by cyclic AMP
    • Wei LH, Morris SM Jr, Cederbaum SD, et al. Induction of arginase II in human caco-2 tumor cells by cyclic AMP. Arch Biochem Biophys 2000;374:255-60.
    • (2000) Arch. Biochem. Biophys. , vol.374 , pp. 255-260
    • Wei, L.H.1    Morris S.M., Jr.2    Cederbaum, S.D.3
  • 112
    • 0031013624 scopus 로고    scopus 로고
    • Coinduction of nitric-oxide synthase and arginase I in cultured rat peritoneal macrophages and rat tissues in vivo by lipopolysaccharide
    • Sonoki T, Nagasaki A, Gotoh T, et al. Coinduction of nitric-oxide synthase and arginase I in cultured rat peritoneal macrophages and rat tissues in vivo by lipopolysaccharide. J Biol Chem 1997; 272:3689-93.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3689-3693
    • Sonoki, T.1    Nagasaki, A.2    Gotoh, T.3
  • 113
    • 17344374016 scopus 로고    scopus 로고
    • Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells
    • Morris SM Jr, Kepka-Lenhart D, Chen LC. Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells. Am J Physiol 1998;275:E740-7.
    • (1998) Am. J. Physiol. , vol.275
    • Morris S.M., Jr.1    Kepka-Lenhart, D.2    Chen, L.C.3
  • 114
    • 0033865650 scopus 로고    scopus 로고
    • IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells
    • Wei LH, Jacobs AT, Morris SM Jr, et al. IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells. Am J Physiol Cell Physiol 2000; 279:C248-56.
    • (2000) Am. J. Physiol. Cell Physiol. , vol.279
    • Wei, L.H.1    Jacobs, A.T.2    Morris S.M., Jr.3
  • 115
    • 0029788854 scopus 로고    scopus 로고
    • Arginase activity determination: A marker of large bowel mucosa proliferation
    • Kocna P, Fric P, Zavoral M, et al. Arginase activity determination: a marker of large bowel mucosa proliferation. Eur J Clin Chem Clin Biochem 1996;34:619-23.
    • (1996) Eur. J. Clin. Chem. Clin. Biochem. , vol.34 , pp. 619-623
    • Kocna, P.1    Fric, P.2    Zavoral, M.3
  • 116
    • 0032808120 scopus 로고    scopus 로고
    • Ornithine decarboxylase in colonic mucosa from patients with moderate or severe Crohn's disease and ulcerative colitis
    • Ricci G, Stabellini G, Bersani G, et al. Ornithine decarboxylase in colonic mucosa from patients with moderate or severe Crohn's disease and ulcerative colitis. Eur J Gastroenterol Hepatol 1999; 11:903-4.
    • (1999) Eur. J. Gastroenterol. Hepatol. , vol.11 , pp. 903-904
    • Ricci, G.1    Stabellini, G.2    Bersani, G.3
  • 117
    • 0026557851 scopus 로고
    • Polyamine metabolism in colonic mucosa from patients with ulcerative colitis
    • Obayashi M, Matsui-Yuasa I, Matsumoto T, et al. Polyamine metabolism in colonic mucosa from patients with ulcerative colitis. Am J Gastroenterol 1992;87:736-40.
    • (1992) Am. J. Gastroenterol. , vol.87 , pp. 736-740
    • Obayashi, M.1    Matsui-Yuasa, I.2    Matsumoto, T.3
  • 118
    • 0032857184 scopus 로고    scopus 로고
    • Increased colonic ornithine decarboxylase activity in inflammatory bowel disease in children
    • Pillai RB, Tolia V, Rabah R, et al. Increased colonic ornithine decarboxylase activity in inflammatory bowel disease in children. Dig Dis Sci 1999;44:1565-70.
    • (1999) Dig. Dis. Sci. , vol.44 , pp. 1565-1570
    • Pillai, R.B.1    Tolia, V.2    Rabah, R.3
  • 119
    • 0029155651 scopus 로고
    • Beneficial effects of L-arginine on intestinal epithelial restitution after ischemic damage in rats
    • Raul F, Galluser M, Schleiffer R, et al. Beneficial effects of L-arginine on intestinal epithelial restitution after ischemic damage in rats. Digestion 1995;56:400-5.
    • (1995) Digestion , vol.56 , pp. 400-405
    • Raul, F.1    Galluser, M.2    Schleiffer, R.3
  • 120
    • 0036250020 scopus 로고    scopus 로고
    • Protective effect of dietary supplementation with L-arginine and L-carnitine on hypoxia/reoxygenation-induced necrotizing enterocolitis in young mice
    • Akisu M, Ozmen D, Baka M, et al. Protective effect of dietary supplementation with L-arginine and L-carnitine on hypoxia/reoxygenation-induced necrotizing enterocolitis in young mice. Biol Neonate 2002;81:260-5.
    • (2002) Biol. Neonate , vol.81 , pp. 260-265
    • Akisu, M.1    Ozmen, D.2    Baka, M.3
  • 121
    • 0034644851 scopus 로고    scopus 로고
    • Evaluation of oxidative stress in experimental colitis: Effects of L-arginine-nitric oxide pathway manipulation
    • Seven A, Seymen O, Inci F, et al. Evaluation of oxidative stress in experimental colitis: effects of L-arginine-nitric oxide pathway manipulation. J Toxicol Environ Health A 2000;61:167-76.
    • (2000) J. Toxicol. Environ. Health A , vol.61 , pp. 167-176
    • Seven, A.1    Seymen, O.2    Inci, F.3
  • 122
    • 0034800458 scopus 로고    scopus 로고
    • Effect of L-arginine on the course of experimental colitis
    • Mane J, Fernandez-Banares F, Ojanguren I, et al. Effect of L-arginine on the course of experimental colitis. Clin Nutr 2001; 20:415-22.
    • (2001) Clin. Nutr. , vol.20 , pp. 415-422
    • Mane, J.1    Fernandez-Banares, F.2    Ojanguren, I.3
  • 123
    • 4243327437 scopus 로고    scopus 로고
    • Protective role of arginase in Citrobacter rodentium colitis
    • Gobert AP, Cheng Y, Mersey BD, et al. Protective role of arginase in Citrobacter rodentium colitis. Gastroenterology 2002; 122:A44.
    • (2002) Gastroenterology , vol.122
    • Gobert, A.P.1    Cheng, Y.2    Mersey, B.D.3
  • 124
    • 0032787622 scopus 로고    scopus 로고
    • Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization
    • Boucher JL, Moali C, Tenu JP. Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. Cell Mol Life Sci 1999;55:1015-28.
    • (1999) Cell Mol. Life Sci. , vol.55 , pp. 1015-1028
    • Boucher, J.L.1    Moali, C.2    Tenu, J.P.3
  • 125
    • 0032555182 scopus 로고    scopus 로고
    • Substrate specificity of NO synthases: Detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine
    • Moali C, Boucher JL, Sari MA, et al. Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine. Biochemistry 1998;37:10453-60.
    • (1998) Biochemistry , vol.37 , pp. 10453-10460
    • Moali, C.1    Boucher, J.L.2    Sari, M.A.3
  • 126
    • 0029113021 scopus 로고
    • Serum nitrate levels in ulcerative colitis and Crohn's disease
    • Oudkerk Pool M, Bouma G, Visser JJ, et al. Serum nitrate levels in ulcerative colitis and Crohn's disease. Scand J Gastroenterol 1995;30:784-8.
    • (1995) Scand. J. Gastroenterol. , vol.30 , pp. 784-788
    • Oudkerk Pool, M.1    Bouma, G.2    Visser, J.J.3


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