Role of bacterial intimin in colonic hyperplasia and inflammation

Science

Volumn 285, Issue 5427, 1999, Pages 588-591

  Higgins, Lisa M ^a   Frankel, Gad ^b   Connerton, Ian ^c   Gonçalves, Nathalie S ^a   Dougan, Gordon ^b   MacDonald, Thomas T ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INTIMIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CITROBACTER; COLON MUCOSA; ENTEROBACTER INFECTION; ESCHERICHIA COLI; GASTROENTERITIS; HUMAN; INTESTINE MUCOSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION;

ADHESINS, BACTERIAL; ANIMALS; BACTERIAL ADHESION; BACTERIAL OUTER MEMBRANE PROTEINS; CARRIER PROTEINS; CITROBACTER; COLITIS; COLON; CYTOKINES; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYPERPLASIA; INTERFERON TYPE II; INTESTINAL MUCOSA; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; RECEPTORS, CELL SURFACE; T-LYMPHOCYTES; TH1 CELLS;

BACTERIA (MICROORGANISMS); CITROBACTER RODENTIUM; ENTEROBACTER; ESCHERICHIA COLI;

EID: 0033597901     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5427.588     Document Type: Article

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29. G. F. and G. D. are supported by the Wellcome Trust. L.M.H and N.S.G. are supported by the Crohn's in Childhood Research Association. We thank S. Daniell for the purification of int280 and M.F. Kagnoff for the gift of the plasmids for cytokine RT-PCR.