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Volumn 6, Issue 3, 2008, Pages 230-238

Suppression of HIV replication in vitro by CpG and CpG conjugatd to the non toxic B subunit of cholera toxin

Author keywords

Antivirals; Chemokines; CpG; CTB; HIV

Indexed keywords

ANTIBODY CONJUGATE; CPG OLIGODEOXYNUCLEOTIDE; CPG OLIGODEOXYNUCLEOTIDE CHOLERA TOXIN B SUBUNIT CONJUGATE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA;

EID: 47749130824     PISSN: 1570162X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016208784325038     Document Type: Review
Times cited : (5)

References (39)
  • 1
    • 0034622980 scopus 로고    scopus 로고
    • Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate
    • Devito C, Hinkula J, Kaul R, et al. Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate. AIDS 2000; 14:1917-20.
    • (2000) AIDS , vol.14 , pp. 1917-1920
    • Devito, C.1    Hinkula, J.2    Kaul, R.3
  • 3
    • 0035576930 scopus 로고    scopus 로고
    • Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women
    • Belec L, Ghys PD, Hocini H, et al. Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women. J Infect Dis 2001; 184:1412-22.
    • (2001) J Infect Dis , vol.184 , pp. 1412-1422
    • Belec, L.1    Ghys, P.D.2    Hocini, H.3
  • 4
    • 33748109942 scopus 로고    scopus 로고
    • Innate host defense of human vaginal and cervical mucosae
    • Cole AM. Innate host defense of human vaginal and cervical mucosae. Curr Top Microbiol Immunol 2006; 306:199-230.
    • (2006) Curr Top Microbiol Immunol , vol.306 , pp. 199-230
    • Cole, A.M.1
  • 5
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003; 85:85-95.
    • (2003) Immunol Lett , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 6
    • 0346731246 scopus 로고    scopus 로고
    • How we detect microbes and respond to them: The Toll-like receptors and their transducers
    • Beutler B, Hoebe K, Du X, Ulevitch RJ. How we detect microbes and respond to them: the Toll-like receptors and their transducers. J Leukoc Biol 2003; 74:479-85.
    • (2003) J Leukoc Biol , vol.74 , pp. 479-485
    • Beutler, B.1    Hoebe, K.2    Du, X.3    Ulevitch, R.J.4
  • 7
    • 0142031430 scopus 로고    scopus 로고
    • Role of Toll-like receptors in pathogen recognition
    • Janssens S, Beyaert R. Role of Toll-like receptors in pathogen recognition. Clin Microbiol Rev 2003; 16:637-46.
    • (2003) Clin Microbiol Rev , vol.16 , pp. 637-646
    • Janssens, S.1    Beyaert, R.2
  • 8
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002; 20:709-60.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 9
    • 33645790032 scopus 로고    scopus 로고
    • Novel immunostimulatory agent based on CpG oligodeoxynucleotide linked to the non-toxic B subunit of cholera toxin
    • Adamsson J, Lindblad M, Lundqvist A, et al. Novel immunostimulatory agent based on CpG oligodeoxynucleotide linked to the non-toxic B subunit of cholera toxin. J Immunol 2006; 176:4902-13.
    • (2006) J Immunol , vol.176 , pp. 4902-4913
    • Adamsson, J.1    Lindblad, M.2    Lundqvist, A.3
  • 10
    • 3042725534 scopus 로고    scopus 로고
    • CpG DNA as a potent inducer of mucosal immunity: Implications for immunoprophylaxis and immunotherapy of mucosal infections
    • Harandi AM, Holmgren J. CpG DNA as a potent inducer of mucosal immunity: implications for immunoprophylaxis and immunotherapy of mucosal infections. Curr Opin Investig Drugs 2004; 5:141-5.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 141-145
    • Harandi, A.M.1    Holmgren, J.2
  • 11
    • 0037223705 scopus 로고    scopus 로고
    • A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection
    • Harandi AM, Eriksson K, Holmgren J. A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection. J Virol 2003; 77:953-62.
    • (2003) J Virol , vol.77 , pp. 953-962
    • Harandi, A.M.1    Eriksson, K.2    Holmgren, J.3
  • 12
    • 2442551764 scopus 로고    scopus 로고
    • The potential of immunostimulatory CpG DNA for inducing immunity against genital herpes: Opportunities and challenges
    • Harandi AM. The potential of immunostimulatory CpG DNA for inducing immunity against genital herpes: opportunities and challenges. J Clin Virol 2004; 30:207-10.
    • (2004) J Clin Virol , vol.30 , pp. 207-210
    • Harandi, A.M.1
  • 13
    • 0036827534 scopus 로고    scopus 로고
    • Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection
    • Pyles RB, Higgins D. Chalk C, et al. Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection. J Virol 2002; 76:11387-96.
    • (2002) J Virol , vol.76 , pp. 11387-11396
    • Pyles, R.B.1    Higgins, D.2    Chalk, C.3
  • 14
    • 0042208151 scopus 로고    scopus 로고
    • Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2
    • Ashkar AA, Bauer S, Mitchell WJ, et al. Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2. J Virol 2003; 77:8948-56.
    • (2003) J Virol , vol.77 , pp. 8948-8956
    • Ashkar, A.A.1    Bauer, S.2    Mitchell, W.J.3
  • 15
    • 33646744394 scopus 로고    scopus 로고
    • Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in. the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital-herpes
    • Tengvall S, Lundqvist A, Eisenberg RJ, et al. Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in. the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital-herpes. J Virol 2006; 80:5283-91.
    • (2006) J Virol , vol.80 , pp. 5283-5291
    • Tengvall, S.1    Lundqvist, A.2    Eisenberg, R.J.3
  • 16
    • 7644230107 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides block human immunodefidency virus type 1 replication in human lymphoid tissue infected ex vivo
    • Schlaepfer E, Audige A, von Beust B, et al. CpG oligodeoxynucleotides block human immunodefidency virus type 1 replication in human lymphoid tissue infected ex vivo. J Virol 2004; 78:12344-54.
    • (2004) J Virol , vol.78 , pp. 12344-12354
    • Schlaepfer, E.1    Audige, A.2    von Beust, B.3
  • 17
    • 0018721005 scopus 로고
    • Evaluation of a ganglioside immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin
    • Back E, Svennerholm AM, Holmgren J, Mouby R. Evaluation of a ganglioside immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin. J Clin Microbiol 1979; 10:791-5.
    • (1979) J Clin Microbiol , vol.10 , pp. 791-795
    • Back, E.1    Svennerholm, A.M.2    Holmgren, J.3    Mouby, R.4
  • 18
    • 0030451775 scopus 로고    scopus 로고
    • Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates
    • Jansson M, Popovic M, Karlsson A, et al. Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates. Proc Natl Acad Sci USA 1996; 93:15382-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15382-15387
    • Jansson, M.1    Popovic, M.2    Karlsson, A.3
  • 19
    • 1842415431 scopus 로고    scopus 로고
    • Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
    • Bjorndal A, Deng H, Jansson M, et al. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype. J Virol 1997; 71:7478-87.
    • (1997) J Virol , vol.71 , pp. 7478-7487
    • Bjorndal, A.1    Deng, H.2    Jansson, M.3
  • 20
    • 0025232737 scopus 로고
    • Replicative capacity of HIV-2, like HIV-1, correlates with severity of immunodeficiency
    • Albert J, Naucler A, Bottiger B, et al. Replicative capacity of HIV-2, like HIV-1, correlates with severity of immunodeficiency. AIDS 1990; 4:291-5.
    • (1990) AIDS , vol.4 , pp. 291-295
    • Albert, J.1    Naucler, A.2    Bottiger, B.3
  • 21
    • 0037289001 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): Frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies
    • Lazarus R, Klimecki WT, Raby BA, et al. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 2003; 81:85-91.
    • (2003) Genomics , vol.81 , pp. 85-91
    • Lazarus, R.1    Klimecki, W.T.2    Raby, B.A.3
  • 22
    • 33749003484 scopus 로고    scopus 로고
    • Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors
    • El Andaloussi A, Sonabend AM, Han Y. Lesniak MS. Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors. Glia 2006; 54:526-35.
    • (2006) Glia , vol.54 , pp. 526-535
    • El Andaloussi, A.1    Sonabend, A.M.2    Han, Y.3    Lesniak, M.S.4
  • 23
    • 4043065769 scopus 로고    scopus 로고
    • Necessity of oligonucleotide aggregation for toll-like receptor 9 activation
    • Wu CC, Lee J, Raz E, et al. Necessity of oligonucleotide aggregation for toll-like receptor 9 activation. J Biol Chem 2004; 279:33071-8.
    • (2004) J Biol Chem , vol.279 , pp. 33071-33078
    • Wu, C.C.1    Lee, J.2    Raz, E.3
  • 24
    • 18644383289 scopus 로고    scopus 로고
    • Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and - independent pathways
    • Yasuda K, Yu P, Kirschning CJ, et al. Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and - independent pathways. J Immunol 2005; 174:6129-36.
    • (2005) J Immunol , vol.174 , pp. 6129-6136
    • Yasuda, K.1    Yu, P.2    Kirschning, C.J.3
  • 25
    • 3142697714 scopus 로고    scopus 로고
    • TLR9 is localized in the endoplasmic reticulum prior to stimulation
    • Leifer CA, Kennedy MN, Mazzoni A, et al. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J Immunol 2004; 173:1179-83.
    • (2004) J Immunol , vol.173 , pp. 1179-1183
    • Leifer, C.A.1    Kennedy, M.N.2    Mazzoni, A.3
  • 26
    • 18644369007 scopus 로고    scopus 로고
    • CpG-independent synergistic induction of beta-chemokines and a dendritic cell phenotype by orthophosphorothioate oligodeoxynucleotides and granulocyte-macrophage colony-stimulating factor in elutriated human primary monocytes
    • Wang J, Alvarez R, Roderiquez G, et al. CpG-independent synergistic induction of beta-chemokines and a dendritic cell phenotype by orthophosphorothioate oligodeoxynucleotides and granulocyte-macrophage colony-stimulating factor in elutriated human primary monocytes. J Immunol 2005; 174:6113-21.
    • (2005) J Immunol , vol.174 , pp. 6113-6121
    • Wang, J.1    Alvarez, R.2    Roderiquez, G.3
  • 27
    • 4744368053 scopus 로고    scopus 로고
    • Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation
    • Vollmer J, Weeratna RD, Jurk M, et al. Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation. Immunology 2004; 113:212-23.
    • (2004) Immunology , vol.113 , pp. 212-223
    • Vollmer, J.1    Weeratna, R.D.2    Jurk, M.3
  • 28
    • 33751101366 scopus 로고    scopus 로고
    • Immunostimulatory PyNTTTTGT oligodeoxynucleotides: Structural properties and refinement of the active motif
    • Rodriguez JM, Elias F, Flo J, et al. Immunostimulatory PyNTTTTGT oligodeoxynucleotides: structural properties and refinement of the active motif. Oligonucleotides 2006; 16:275-85.
    • (2006) Oligonucleotides , vol.16 , pp. 275-285
    • Rodriguez, J.M.1    Elias, F.2    Flo, J.3
  • 29
    • 0023447274 scopus 로고
    • Phosphorothioate analogs of oligodeoxynucleotides: Inhibitors of replication d cytopathic effects of human immunodeficiency virus
    • Matsukura M, Shinuzuka K, Zon G, et al. Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication d cytopathic effects of human immunodeficiency virus. Proc Natl Acad Sci USA 1987; 84:7706-10.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7706-7710
    • Matsukura, M.1    Shinuzuka, K.2    Zon, G.3
  • 30
    • 0033056726 scopus 로고    scopus 로고
    • Oligonucleotides as inhibitors of human immunodeficiency virus
    • Field AK. Oligonucleotides as inhibitors of human immunodeficiency virus. Curr Opin Mol Ther 1999; 1:323-31.
    • (1999) Curr Opin Mol Ther , vol.1 , pp. 323-331
    • Field, A.K.1
  • 31
    • 0027983025 scopus 로고
    • Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion
    • Wyatt JR, Vickers TA, Roberson JL, et al. Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proc Natl Acad Sci USA 1994; 91:1356-60.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1356-1360
    • Wyatt, J.R.1    Vickers, T.A.2    Roberson, J.L.3
  • 32
    • 0030200369 scopus 로고    scopus 로고
    • Guanine-rich oligonucleotide modified at the 5′ terminal by dimethoxytrityl residue inhibits HIV-1 replication by specific interaction with the envelope glycoprotein
    • Agatsuma T, Yamamoto I, Furukawa H, Nishigaki T. Guanine-rich oligonucleotide modified at the 5′ terminal by dimethoxytrityl residue inhibits HIV-1 replication by specific interaction with the envelope glycoprotein. Antiviral Res 1996; 31:137-48.
    • (1996) Antiviral Res , vol.31 , pp. 137-148
    • Agatsuma, T.1    Yamamoto, I.2    Furukawa, H.3    Nishigaki, T.4
  • 33
    • 36348945135 scopus 로고    scopus 로고
    • Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation
    • Jurk M, Vollmer J. Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation. Biodrugs 2007; 21:387-401.
    • (2007) Biodrugs , vol.21 , pp. 387-401
    • Jurk, M.1    Vollmer, J.2
  • 34
    • 14944345375 scopus 로고    scopus 로고
    • ODNs treatments of HIV-1 infected patients may cause the decline of transmission in high risk populations - A review, hypothesis and implications
    • Becker Y. CpG ODNs treatments of HIV-1 infected patients may cause the decline of transmission in high risk populations - A review, hypothesis and implications. Virus Genes 2005; 30:251-266.
    • (2005) Virus Genes , vol.30 , pp. 251-266
    • Becker, Y.C.1
  • 35
    • 2542459199 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells
    • Scheller C, Ullrich A, McPherson K, et al. CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells. J Biol Chem 2004; 279:21897-21902.
    • (2004) J Biol Chem , vol.279 , pp. 21897-21902
    • Scheller, C.1    Ullrich, A.2    McPherson, K.3
  • 36
    • 33746671960 scopus 로고    scopus 로고
    • A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide
    • Shen J, Iwasaki A. A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide. J Clin Invest 2006; 116:2237-2243.
    • (2006) J Clin Invest , vol.116 , pp. 2237-2243
    • Shen, J.1    Iwasaki, A.2
  • 37
    • 0037546944 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) and TLR9 signaling results in HIV-long terminal repeat trans-activation and HIV replication in HIV-1 transgenic mouse spleen cells: Implications of simultaneous activation of TLRs on HIV replication
    • Equils O, Schito MI, Karahashi H, et al. Toll-like receptor 2 (TLR2) and TLR9 signaling results in HIV-long terminal repeat trans-activation and HIV replication in HIV-1 transgenic mouse spleen cells: Implications of simultaneous activation of TLRs on HIV replication. J Immunol 2003; 170:5159-5164.
    • (2003) J Immunol , vol.170 , pp. 5159-5164
    • Equils, O.1    Schito, M.I.2    Karahashi, H.3
  • 38
    • 33947595439 scopus 로고    scopus 로고
    • Dual activity of phosphorothioate CpG oligodeoxynucleotides on HIV - Reactivation of latent provirus and inhibition of productive infection in human T cells
    • Scheller C, Ullrich A, Lamla S, et al. Dual activity of phosphorothioate CpG oligodeoxynucleotides on HIV - Reactivation of latent provirus and inhibition of productive infection in human T cells. Ann N Y Acad Sci 2006; 1091: 540-547.
    • (2006) Ann N Y Acad Sci , vol.1091 , pp. 540-547
    • Scheller, C.1    Ullrich, A.2    Lamla, S.3
  • 39
    • 27644446403 scopus 로고    scopus 로고
    • The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques
    • Wang Y, Abel K, Lantz K, et al. The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques. J Virol 2005; 79:14355-70.
    • (2005) J Virol , vol.79 , pp. 14355-14370
    • Wang, Y.1    Abel, K.2    Lantz, K.3


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