Association study of the decreased serum BDNF concentrations in amnestic mild cognitive impairment and the Val66Met polymorphism in Chinese han

Journal of Clinical Psychiatry

Volumn 69, Issue 7, 2008, Pages 1104-1111

  Yu, Hui ^a   Zhang, Zhijun ^a   Shi, Yongmei ^a   Bai, Feng ^a   Xie, Chunming ^a   Qian, Yun ^a   Yuan, Yonggui ^a   Deng, Linglon ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CHINESE; COGNITION; COGNITIVE DEFECT; CONTROL GROUP; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPISODIC MEMORY; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LEARNING TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

EID: 47749126147     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v69n0710     Document Type: Article

References (62)

1. Terry RD. Alzheimer's disease and the aging brain. J Geriatr Psychiatry Neurol 2006;19:125-128
2. Winblad B, Palmer K. Kivipelto M. et al. Mild cognitive impairment-beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Intern Med 2004;256: 240-246
3. Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999;56:303-308
4. Petersen RC. Mild cognitive impairment as a diagnostic entity. J Intern Med 2004;256:183-194
5. Knusel B, Gao H. Neurotrophins and Alzheimer's disease: beyond the cholinergic neurons. Life Sci 1996;58:2019-2027
6. Murer MG, Boissiere F, Yan Q, et al. An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease. Neuroscience 1999;88:1015-1032
7. Murer MG, Yan Q, Raisman-Vozari R. Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Prog Neurobiol 2001;63:71-124
8. Tong L, Balazs R, Thornton PL, et al. Beta-Amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. J Neurosci 2004;24:6799-6809
9. Wang DC. Chen SS, Lee YC, et al. Amyloid-beta at sublethal level impairs BDNF-induced arc expression in cortical neurons. Neurosci Lett 2006;398:78-82
10. Elliott E, Atlas R. Lange A, et al. Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3 Kinase signalling mechanism. Eur J Neurosci 2005;22:1081-1089
11. Wu ZL, Ciallella JR, Flood DG, et al. Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease. Neurobiol Aging 2006;27:377-386
12. Hellweg R, Lohmann P, Huber R, et al. Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment. Learn Mem 2006;13:63-71
13. Phillips HS, Hains JM, Armanini M. et al. BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease. Neuron 1991; 7:695-702
14. Connor B, Young D. Yan Q. et al. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain Res Mol Brain Res 1997;49:71-81
15. Narisawa-Saito M, Wakabayashi K, Tsuji S, et al. Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease. Neuroreport 1996;7:2925-2928
16. Ferrer I, Marin C. Rey MJ, et al. BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies. J Neuropathol Exp Neurol 1999 Jul;58(7):729-739
17. Holsinger RM, Schnarr J. Henry P, et al. Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymcrasc chain reaction: decreased levels in Alzheimer's disease. Brain Res Mol Brain Res 2000;76:347-354
18. Hock C, Heese K, Hulette C, et al. Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol 2000;57:846-851
19. Durany N, Michel T, Kurt I, et al. Brain-derived neurotrophic factor and ncurotrophin-3 levels in Alzheimer's disease brains. Int J Dev Neurosci 2000 Dec;18(8):807-813
20. Peng S, Wuu J, Mufson EJ, et al. Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease. J Neurochem 2005;93: 1412-1421
21. Pan W, Banks WA, Fasold MB, et al. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998; 37:1553-1561
22. Radka SF, Hoist PA, Fritsche MC, et al. Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay. Brain Res 1996;709:122-130
23. Laske C. Stransky E. Leyhe T, et al. Stage-dependent BDNF scrum concentrations in Alzheimer's disease. J Neural Transm 2006; 113: 1217-1224
24. Yasutake C. Kuroda K, Yanagawa T, et al. Scrum BDNF, TNF-alpha and IL-l beta levels in dementia patients: comparison between Alzheimer's disease and vascular dementia. Eur Arch Psychiatry Clin Neurosci 2006 Oct;256(7):402-406
25. Laske C, Stransky E, Leyhe T, et al. BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls. J Psychiatr Res 2007 Aug;41 (5):387-394
26. Bertram L, Tanzi RE. Alzheimer's disease: one disorder, too many genes? Hum Mol Genet 2004 Apr 1;13 Spec No 1:R135-R141
27. Egan MF, Kojima M, Callicott JH, et al. The BDNF val66mct polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003; 112:257-269
28. Chen ZY, Patel PD, Sant G, et al. Variant brain-derived neurotrophic factor (BDNF) (Mct66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J Neurosci 2004 May 5;24(18):4401-4411
29. Ventriglia M, Chiavetto LB, Benussi L, et al. Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease. Mol Psychiatry 2002;7:136-137
30. Matsushita S, Arai H, Matsui T, et al. Brain-derived neurotrophic factor gene polymorphisms and Alzheimer's disease. J Neural Transm 2005; 112:703-711
31. Bian JT, Zhang J W, Zhang ZX, et al. Association analysis of brain-derived neurotrophic factor (BDNF) gene 196 A/G polymorphism with Alzheimer's disease (AD) in mainland Chinese. Neurosci Lett 2005; 387:11-16
32. Tsai SJ, Hong CJ, Liu 11C, et al. Association analysis of brain-derived neurotrophic factor Val66Met polymorphisms with Alzheimer's disease and age of onset. Neuropsychobiology 2004;49:10-12
33. Li Y, Rowland C, Tacey K, et al. The BDNF Val66Mct polymorphism is not associated with late onset Alzheimer's disease in three case-control samples [letter]. Mol Psychiatry 2005;10:809-810
34. Bodner SM, Berrettini W, van Deerlin V, et al. Genetic variation in the brain-derived neurotrophic factor gene in Alzheimer's disease. Am I Med Genet B Neuropsychiatr Genet 2005 Apr;134(l):l-5
35. Guo QH, Lv CZ, Hong Z. The reliability and validity analysis of Auditory Verbal Leaming Test. Chinese Ment Health J 2001; 15:13-15
36. Katzman R, Zhang MY, Ouang-Ya-Qu. et al. A Chinese version of the Mini-Mental State Examination: impact of illiteracy in a Shanghai dementia survey. J Clin Epidemiol 1988;41 (10):971-978
37. Morris JC. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993;43:2412-2414
38. McKhann G, Drachman D. Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-944
39. Rosen WG. Terry RD, Fuld PA, et al. Pathological verification of ischemic score differentiation of dementias. Ann Neurol 1980;7:486-488
40. Lezak MD. Neuropsychological Assessment. 2nd ed. New York, NY: Oxford University Press; 1983:395-402
41. Monsch AU, Bondi MW, Butters N, ct al. Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type. Arch Neurol 1992;49:1253-1258
42. Wechsler D. Wechsler Adult Intelligence Scale-Revised Manual. San Antonio, Tex: Psychological Corp; 1981
43. Gordon NG. The Trail Making Test in neuropsychological diagnosis. J Clin Psychol 1972;28:167-169
44. Libon DJ. Malamut BL, Swenson R. et al. Further analyses of clock drawings among demented and nondemented older subjects. Arch Clin Neuropsychol 1996; 11.(3): 193-205
45. Chen QY, Chen Q, Feng GY, et al. Association between the brain-derived neurotrophic factor (BDNF) gene and schizophrenia in the Chinese population. Neurosci Lett 2006;397:285-290
46. Flicker C, Ferris SH, Reisberg B. Mild cognitive impairment in the elderly: predictors of dementia. Neurology 1991;41:1.006-1009
47. Aggarwal NT. Wilson RS, Beck TL. et al. Mild cognitive impairment in different functional domains and incident Alzheimer's disease. J Neurol Neurosurg Psychiatry 2005;76:1479-1484
48. Tyler WJ, Alonso M, Bramham CR, et al. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn Mem 2002;9:224-237
49. Lu B. BDNF and activity-dependent synaptic modulation. Team Mem 2003;10:86-98
50. Korte M, Carroll P, Wolf E. et al. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci USA 1995;92:8856-8860
51. Korte M, Griesbeck O, Gravel C, et al. Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci USA 1996;93: 12547-12552
52. Masliah E, Mallory M, Alford M, et al. Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease. Neurology 2001;56:127-129
53. Sclkoe DJ. Alzheimer's disease is a synaptic failure. Science 2002;298: 789-791
54. Gylys KH, Fein JA, Yang F, et al. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am J Pathol 2004;165:1809-1817
55. Counts SE, Nadeem M, Lad SP, et al. Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment. J Neuropathol Exp Neurol 2006;65:592-601
56. Karege F, Schwald M, Cisse M. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 2002;328:261-264
57. Lee J, Fukumoto H, Orne J, et al. Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms. Exp Neurol 2005; 194:91-96
58. Nilsson LG, Sikström C, Adolfsson R, et al. Genetic markers with high versus low scoring on episodic memory tasks. Behav Genet 1996;26:555-562
59. Bueller JA, Aftab M, Sen S, et al. BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biol Psychiatry 2006;59:812-815
60. Hariri AR. Goldberg TE, Mattay VS. et al. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci 2003;23: 6690-6694
61. Machulda MM, Ward HA, Borowski B, et al. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology 2003;61:500-506
62. Du AT. Schuff N, Amend D. etal. Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry 2001;71: 441-447