메뉴 건너뛰기




Volumn 19, Issue 5, 2008, Pages 1185-1190

Expression of Sonic hedgehog signaling pathway correlates with the tumorigenesis of intraductal papillary mucinous neoplasm of the pancreas

Author keywords

Gli1; Intraductal papillary mucinous neoplasm of the pancreas; Sonic hedgehog

Indexed keywords

MESSENGER RNA; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; GLI1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 47549097016     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.19.5.1185     Document Type: Article
Times cited : (20)

References (31)
  • 1
    • 0029951351 scopus 로고    scopus 로고
    • Intraductal papillary-mucinous tumors of the pancreas: Clinicopathologic features, outcome, and nomenclature
    • Loftus JEV, Olivares-Pakzad BA, Batts KP, et al: Intraductal papillary-mucinous tumors of the pancreas: Clinicopathologic features, outcome, and nomenclature. Gastroenterology 110: 1909-1918, 1996.
    • (1996) Gastroenterology , vol.110 , pp. 1909-1918
    • Loftus, J.E.V.1    Olivares-Pakzad, B.A.2    Batts, K.P.3
  • 2
    • 0027330943 scopus 로고
    • The point mutation of c-Ki-ras at codon 12 in carcinoma of the pancreatic head region and in intraductal mucin-hypersecreting neoplasm of the pancreas
    • Satoh K, Sawai T, Shimosegawa T, et al: The point mutation of c-Ki-ras at codon 12 in carcinoma of the pancreatic head region and in intraductal mucin-hypersecreting neoplasm of the pancreas. Int J Pancreatol 14: 135-143, 1993.
    • (1993) Int J Pancreatol , vol.14 , pp. 135-143
    • Satoh, K.1    Sawai, T.2    Shimosegawa, T.3
  • 3
    • 0029921032 scopus 로고    scopus 로고
    • K-ras mutation and p53 protein accumulation in intraductal mucin-hypersecreting neoplasms of the pancreas
    • Satoh K, Shimosegawa T, Moriizumi S, Koizumi M and Toyota T: K-ras mutation and p53 protein accumulation in intraductal mucin-hypersecreting neoplasms of the pancreas. Pancreas 12: 362-368, 1996.
    • (1996) Pancreas , vol.12 , pp. 362-368
    • Satoh, K.1    Shimosegawa, T.2    Moriizumi, S.3    Koizumi, M.4    Toyota, T.5
  • 4
    • 0027325182 scopus 로고
    • An immunohistochemical study of the c-erbB-2 oncogene product in intraductal mucin-hypersecreting neoplasms and in ductal cell carcinomas of the pancreas
    • Satoh K, Sasano H, Shimosegawa T, et al: An immunohistochemical study of the c-erbB-2 oncogene product in intraductal mucin-hypersecreting neoplasms and in ductal cell carcinomas of the pancreas. Cancer 72: 51-56, 1993.
    • (1993) Cancer , vol.72 , pp. 51-56
    • Satoh, K.1    Sasano, H.2    Shimosegawa, T.3
  • 5
    • 0035878930 scopus 로고    scopus 로고
    • Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors
    • Satoh K, Kaneko K, Hirota M, Masamune A, Satoh A and Shimosegawa T: Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors. Cancer 92: 271-278, 2001.
    • (2001) Cancer , vol.92 , pp. 271-278
    • Satoh, K.1    Kaneko, K.2    Hirota, M.3    Masamune, A.4    Satoh, A.5    Shimosegawa, T.6
  • 6
    • 0032190218 scopus 로고    scopus 로고
    • Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis
    • Fukushige S, Furukawa T, Satoh K, et al: Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis. Cancer Res 58: 4222-4226, 1998.
    • (1998) Cancer Res , vol.58 , pp. 4222-4226
    • Fukushige, S.1    Furukawa, T.2    Satoh, K.3
  • 7
    • 0032471409 scopus 로고    scopus 로고
    • Intraductal papillary-mucionus tumors of the pancreas: Imaging studies and treatment strategies
    • Sugiyama M and Atomi Y: Intraductal papillary-mucionus tumors of the pancreas: imaging studies and treatment strategies. Ann Surg 228: 685-691, 1998.
    • (1998) Ann Surg , vol.228 , pp. 685-691
    • Sugiyama, M.1    Atomi, Y.2
  • 9
    • 0035020633 scopus 로고    scopus 로고
    • Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions
    • Hruban RH, Adsay NV, Albores-Saavedra J, et al: Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol 25: 579-586, 2001.
    • (2001) Am J Surg Pathol , vol.25 , pp. 579-586
    • Hruban, R.H.1    Adsay, N.V.2    Albores-Saavedra, J.3
  • 10
    • 0242270878 scopus 로고    scopus 로고
    • Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
    • Thayer SP, di Magliano MP, Heiser PW, et al: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 425: 851-856, 2003.
    • (2003) Nature , vol.425 , pp. 851-856
    • Thayer, S.P.1    di Magliano, M.P.2    Heiser, P.W.3
  • 11
    • 16444378654 scopus 로고    scopus 로고
    • Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells
    • Prasad NB, Biankin AV, Fukushima N, et al: Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells. Cancer Res 65: 1619-1626, 2005.
    • (2005) Cancer Res , vol.65 , pp. 1619-1626
    • Prasad, N.B.1    Biankin, A.V.2    Fukushima, N.3
  • 12
    • 33747882404 scopus 로고    scopus 로고
    • Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasms: Clinical implications of mRNA levels in pancreatic juice
    • Ohuchida K, Mizumoto K, Fujita H, et al: Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasms: clinical implications of mRNA levels in pancreatic juice. J Pathol 210: 42-48, 2006.
    • (2006) J Pathol , vol.210 , pp. 42-48
    • Ohuchida, K.1    Mizumoto, K.2    Fujita, H.3
  • 14
    • 0347635451 scopus 로고    scopus 로고
    • A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line
    • Nishimaki H, Kasai K, Kozaki K, et al: A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line. Biochem Biophys Res Commun 314: 313-320,2004.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 313-320
    • Nishimaki, H.1    Kasai, K.2    Kozaki, K.3
  • 15
    • 33748987654 scopus 로고    scopus 로고
    • Identification of cripto-1 as a novel serologic marker for breast and colon cancer
    • Bianco C, Strizzi L, Mancino M, et al: Identification of cripto-1 as a novel serologic marker for breast and colon cancer. Clin Cancer Res 12: 5158-5164, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 5158-5164
    • Bianco, C.1    Strizzi, L.2    Mancino, M.3
  • 16
    • 33644849523 scopus 로고    scopus 로고
    • Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal
    • Sheng T, Chi S, Zhang X and Xie J: Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal. J Biol Chem 281: 9-12, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 9-12
    • Sheng, T.1    Chi, S.2    Zhang, X.3    Xie, J.4
  • 17
    • 34347226348 scopus 로고    scopus 로고
    • Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1and the RAS-MEK/AKT pathways
    • Stecca B, Mas C, Clement V, et al: Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1and the RAS-MEK/AKT pathways. Proc Natl Acad Sci USA 104: 5895-5900, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5895-5900
    • Stecca, B.1    Mas, C.2    Clement, V.3
  • 18
    • 0032126734 scopus 로고    scopus 로고
    • Transducing Hedgehog: The story so far
    • Ingham PW: Transducing Hedgehog: the story so far. EMBO J 17: 3505-3511, 1998.
    • (1998) EMBO J , vol.17 , pp. 3505-3511
    • Ingham, P.W.1
  • 20
    • 0037212983 scopus 로고    scopus 로고
    • Hedgehog signaling in pancreas development
    • Hebrok M: Hedgehog signaling in pancreas development. Mech Dev 120: 45-57, 2003.
    • (2003) Mech Dev , vol.120 , pp. 45-57
    • Hebrok, M.1
  • 21
    • 0036559186 scopus 로고    scopus 로고
    • Gli and hedgehog in cancer: Tumours, embryos and stem cells
    • Ruiz i Altaba A, Sanchez P and Dahmane N: Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev Cancer 2: 361-372, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 361-372
    • Ruiz i Altaba, A.1    Sanchez, P.2    Dahmane, N.3
  • 22
    • 2942738996 scopus 로고    scopus 로고
    • The Hedgehog response network: Sensors, switches, and routers
    • Lum L and Beachy PA: The Hedgehog response network: sensors, switches, and routers. Science 304: 1755-1759, 2004.
    • (2004) Science , vol.304 , pp. 1755-1759
    • Lum, L.1    Beachy, P.A.2
  • 23
    • 0842265834 scopus 로고    scopus 로고
    • Hedgehog-Gli signaling in brain tumors: Stem cells and paradevelopmental programs in cancer
    • Ruiz i Altaba A, Stecca B and Sanchez P: Hedgehog-Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer. Cancer Lett 204: 145-157, 2004.
    • (2004) Cancer Lett , vol.204 , pp. 145-157
    • Ruiz i Altaba, A.1    Stecca, B.2    Sanchez, P.3
  • 24
    • 0345059765 scopus 로고    scopus 로고
    • Hedgehog signalling in cancer formation and maintenance
    • Pasca di Magliano M and Hebrok M: Hedgehog signalling in cancer formation and maintenance. Nat Rev Cancer 3: 903-911, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 903-911
    • Pasca di Magliano, M.1    Hebrok, M.2
  • 25
    • 4344659678 scopus 로고    scopus 로고
    • Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
    • Sanchez P, Hernandez AM, Stecca B, et al: Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc Natl Acad Sci USA 101: 12561-12566, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 12561-12566
    • Sanchez, P.1    Hernandez, A.M.2    Stecca, B.3
  • 26
    • 15844381336 scopus 로고    scopus 로고
    • Human homolog of patched, a candidate gene for the basal cell nevus syndrome
    • Johnson RL, Rothman AL, Xie J, et al: Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272: 1668-1671, 1996.
    • (1996) Science , vol.272 , pp. 1668-1671
    • Johnson, R.L.1    Rothman, A.L.2    Xie, J.3
  • 27
    • 0031913524 scopus 로고    scopus 로고
    • Activating Smoothened mutations in sporadic basal-cell carcinoma
    • Xie J, Murone M, Luoh SM, et al: Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 391: 90-92, 1998.
    • (1998) Nature , vol.391 , pp. 90-92
    • Xie, J.1    Murone, M.2    Luoh, S.M.3
  • 28
    • 0242268525 scopus 로고    scopus 로고
    • Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
    • Berman DM, Karhadkar SS, Maitra A, et al: Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 425: 846-851, 2003.
    • (2003) Nature , vol.425 , pp. 846-851
    • Berman, D.M.1    Karhadkar, S.S.2    Maitra, A.3
  • 30
    • 34247646461 scopus 로고    scopus 로고
    • Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis
    • Morton JP, Mongeau ME, Klimstra DS, et al: Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis. Proc Natl Acad Sci USA 104: 5103-5108, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5103-5108
    • Morton, J.P.1    Mongeau, M.E.2    Klimstra, D.S.3
  • 31
    • 34347253037 scopus 로고    scopus 로고
    • Oncogenic kras supresses GLI1 degradation and activates hedgehog signaling pathway in pancreatic cancer cells
    • Ji Z, Mei FC, Xie J and Cheng X: Oncogenic kras supresses GLI1 degradation and activates hedgehog signaling pathway in pancreatic cancer cells. J Biol Chem 282: 14048-14055, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 14048-14055
    • Ji, Z.1    Mei, F.C.2    Xie, J.3    Cheng, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.