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Volumn 294, Issue 6, 2008, Pages

Hepatic insulin resistance induced by prenatal alcohol exposure is associated with reduced PTEN and TRB3 acetylation in adult rat offspring

Author keywords

Akt; Gluconeogenesis; Intrauterine environment

Indexed keywords

3 MERCAPTOPICOLINIC ACID; ALCOHOL; COMPLEMENTARY DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE; INSULIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN KINASE B; PROTEIN KINASE C ZETA; PYRUVIC ACID; TRIBBLES 3 PROTEIN; UNCLASSIFIED DRUG; CENTRAL DEPRESSANT AGENT; HISTONE ACETYLTRANSFERASE; ONCOPROTEIN; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; PTEN PROTEIN, RAT; PYRUVATE DEHYDROGENASE (ACETYL TRANSFERRING) KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; PYRUVIC ACID DERIVATIVE; TRIB3 PROTEIN, RAT;

EID: 47549092773     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00804.2007     Document Type: Article
Times cited : (63)

References (46)
  • 2
    • 0027529974 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): Relation to reduced fetal growth
    • Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36: 62-67, 1993.
    • (1993) Diabetologia , vol.36 , pp. 62-67
    • Barker, D.J.1    Hales, C.N.2    Fall, C.H.3    Osmond, C.4    Phipps, K.5    Clark, P.M.6
  • 3
    • 34249793710 scopus 로고    scopus 로고
    • Reversible acetylation of non histone proteins: Role in cellular function and disease
    • Batta K, Das C, Gadad S, Shandilya J, Kundu TK. Reversible acetylation of non histone proteins: role in cellular function and disease. Subcell Biochem 41: 193-212, 2007.
    • (2007) Subcell Biochem , vol.41 , pp. 193-212
    • Batta, K.1    Das, C.2    Gadad, S.3    Shandilya, J.4    Kundu, T.K.5
  • 5
    • 0014032729 scopus 로고
    • Nuclei from rat liver: Isolation method that combines purity with high yield
    • Blobel G, Potter VR. Nuclei from rat liver: isolation method that combines purity with high yield. Science 154: 1662-1665, 1966.
    • (1966) Science , vol.154 , pp. 1662-1665
    • Blobel, G.1    Potter, V.R.2
  • 6
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376: 599-602, 1995.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 8
    • 0038751824 scopus 로고    scopus 로고
    • Effects of prenatal alcohol exposure on glucose tolerance in the rat offspring
    • Chen L, Nyomba BL. Effects of prenatal alcohol exposure on glucose tolerance in the rat offspring. Metabolism 52: 454-462, 2003.
    • (2003) Metabolism , vol.52 , pp. 454-462
    • Chen, L.1    Nyomba, B.L.2
  • 9
    • 0037320307 scopus 로고    scopus 로고
    • Glucose intolerance and resistin expression in rat offspring exposed to ethanol in utero: Modulation by postnatal high-fat diet
    • Chen L, Nyomba BL. Glucose intolerance and resistin expression in rat offspring exposed to ethanol in utero: modulation by postnatal high-fat diet. Endocrinology 144: 500-508, 2003.
    • (2003) Endocrinology , vol.144 , pp. 500-508
    • Chen, L.1    Nyomba, B.L.2
  • 10
    • 0347993715 scopus 로고    scopus 로고
    • Whole body insulin resistance in rat offspring of mothers consuming alcohol during pregnancy or lactation: Comparing prenatal and postnatal exposure
    • Chen L, Nyomba BL. Whole body insulin resistance in rat offspring of mothers consuming alcohol during pregnancy or lactation: comparing prenatal and postnatal exposure. J Appl Physiol 96: 167-172, 2004.
    • (2004) J Appl Physiol , vol.96 , pp. 167-172
    • Chen, L.1    Nyomba, B.L.2
  • 11
    • 23044432133 scopus 로고    scopus 로고
    • In vivo insulin signaling through PI3-kinase is impaired in skeletal muscle of adult rat offspring exposed to ethanol in utero
    • Chen L, Yao XH, Nyomba BL. In vivo insulin signaling through PI3-kinase is impaired in skeletal muscle of adult rat offspring exposed to ethanol in utero. J Appl Physiol 99: 528-534, 2005.
    • (2005) J Appl Physiol , vol.99 , pp. 528-534
    • Chen, L.1    Yao, X.H.2    Nyomba, B.L.3
  • 12
    • 1342267441 scopus 로고    scopus 로고
    • Insulin resistance of gluconeogenic pathways in neonatal rats after prenatal ethanol exposure
    • Chen L, Zhang T, Nyomba BL. Insulin resistance of gluconeogenic pathways in neonatal rats after prenatal ethanol exposure. Am J Physiol Regul Integr Comp Physiol 286: R554-R559, 2004.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Chen, L.1    Zhang, T.2    Nyomba, B.L.3
  • 13
    • 33748456961 scopus 로고    scopus 로고
    • Intrauterine ethanol exposure results in hypothalamic oxidative stress and neuroendocrine alterations in adult rat offspring
    • Dembele K, Yao XH, Chen L, Nyomba BL. Intrauterine ethanol exposure results in hypothalamic oxidative stress and neuroendocrine alterations in adult rat offspring. Am J Physiol Regul Integr Comp Physiol 291: R79-R802, 2006.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Dembele, K.1    Yao, X.H.2    Chen, L.3    Nyomba, B.L.4
  • 14
    • 0038242819 scopus 로고    scopus 로고
    • TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
    • Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300: 1574-1577, 2003.
    • (2003) Science , vol.300 , pp. 1574-1577
    • Du, K.1    Herzig, S.2    Kulkarni, R.N.3    Montminy, M.4
  • 15
    • 0036239514 scopus 로고    scopus 로고
    • Insulin resistance in adult rat offspring associated with maternal dietary fat and alcohol consumption
    • Elton CW, Pennington JS, Lynch SA, Carver FM, Pennington SN. Insulin resistance in adult rat offspring associated with maternal dietary fat and alcohol consumption. J Endocrinol 173: 63-71, 2002.
    • (2002) J Endocrinol , vol.173 , pp. 63-71
    • Elton, C.W.1    Pennington, J.S.2    Lynch, S.A.3    Carver, F.M.4    Pennington, S.N.5
  • 16
    • 0036288402 scopus 로고    scopus 로고
    • Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states
    • Farese RV. Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states. Am J Physiol Endocrinol Metab 283: E1-E11, 2002.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Farese, R.V.1
  • 18
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24: 7410-7425, 2005.
    • (2005) Oncogene , vol.24 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 19
    • 33744955437 scopus 로고    scopus 로고
    • Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation
    • He L, Simmen FA, Mehendale HM, Ronis MJ, Badger TM. Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation. J Biol Chem 281: 11126-11134, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 11126-11134
    • He, L.1    Simmen, F.A.2    Mehendale, H.M.3    Ronis, M.J.4    Badger, T.M.5
  • 20
    • 0034852862 scopus 로고    scopus 로고
    • Protein kinase C activation: Isozyme-specific effects on metabolism and cardiovascular complications in diabetes
    • Idris I, Gray S, Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia 44: 659-673, 2001.
    • (2001) Diabetologia , vol.44 , pp. 659-673
    • Idris, I.1    Gray, S.2    Donnelly, R.3
  • 21
    • 34848911318 scopus 로고    scopus 로고
    • Paradoxical facilitatory effect of low-dose alcohol consumption on memory mediated by NMDA receptors
    • Kalev-Zylinska ML, During MJ. Paradoxical facilitatory effect of low-dose alcohol consumption on memory mediated by NMDA receptors. J Neurosci 27: 10456-10467, 2007.
    • (2007) J Neurosci , vol.27 , pp. 10456-10467
    • Kalev-Zylinska, M.L.1    During, M.J.2
  • 30
    • 0032746837 scopus 로고    scopus 로고
    • The long-term consequences of intra-uterine protein malnutrition for glucose metabolism
    • Ozanne SE, Hales CN. The long-term consequences of intra-uterine protein malnutrition for glucose metabolism. Proc Nutr Soc 58: 615-619, 1999.
    • (1999) Proc Nutr Soc , vol.58 , pp. 615-619
    • Ozanne, S.E.1    Hales, C.N.2
  • 31
    • 0035998906 scopus 로고    scopus 로고
    • Maternal dietary ethanol consumption is associated with hypertriglyceridemia in adult rat offspring
    • Pennington JS, Shuvaeva TI, Pennington SN. Maternal dietary ethanol consumption is associated with hypertriglyceridemia in adult rat offspring. Alcohol Clin Exp Res 26: 848-855, 2002.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 848-855
    • Pennington, J.S.1    Shuvaeva, T.I.2    Pennington, S.N.3
  • 32
    • 14544282413 scopus 로고    scopus 로고
    • Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434: 113-118, 2005.
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5
  • 33
    • 0035489035 scopus 로고    scopus 로고
    • Intrauterine growth retardation leads to the development of type 2 diabetes in the rat
    • Simmons RA, Templeton LJ, Gertz SJ. Intrauterine growth retardation leads to the development of type 2 diabetes in the rat. Diabetes 50: 2279-2286, 2001.
    • (2001) Diabetes , vol.50 , pp. 2279-2286
    • Simmons, R.A.1    Templeton, L.J.2    Gertz, S.J.3
  • 35
    • 2942530449 scopus 로고    scopus 로고
    • Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states
    • Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states. J Biol Chem 279: 24929-24934, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 24929-24934
    • Standaert, M.L.1    Sajan, M.P.2    Miura, A.3    Kanoh, Y.4    Chen, H.C.5    Farese Jr, R.V.6    Farese, R.V.7
  • 38
    • 33748111665 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
    • Tilg H, Hotamisligil GS. Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 131: 934-945, 2006.
    • (2006) Gastroenterology , vol.131 , pp. 934-945
    • Tilg, H.1    Hotamisligil, G.S.2
  • 39
    • 0032408692 scopus 로고    scopus 로고
    • Fetal growth and consequences for later life
    • Van Assche FA, Holemans K, Aerts L. Fetal growth and consequences for later life. J Perinat Med 26: 337-346, 1998.
    • (1998) J Perinat Med , vol.26 , pp. 337-346
    • Van Assche, F.A.1    Holemans, K.2    Aerts, L.3
  • 40
    • 0032055131 scopus 로고    scopus 로고
    • Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: Comparison with protein kinase B alpha
    • Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha. Biochem J 331: 299-308, 1998.
    • (1998) Biochem J , vol.331 , pp. 299-308
    • Walker, K.S.1    Deak, M.2    Paterson, A.3    Hudson, K.4    Cohen, P.5    Alessi, D.R.6
  • 43
    • 33845453819 scopus 로고    scopus 로고
    • Glucose, dexamethasone and the unfolded protein response regulate TRB3 mRNA expression in 3T3-L1 adipocytes and L6 myotubes
    • Yacoub Wasef SZ, Robinson KA, Berkaw MN, Buse MG. Glucose, dexamethasone and the unfolded protein response regulate TRB3 mRNA expression in 3T3-L1 adipocytes and L6 myotubes. Am J Physiol Endocrinol Metab 291: E1274-E1280, 2006.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Yacoub Wasef, S.Z.1    Robinson, K.A.2    Berkaw, M.N.3    Buse, M.G.4
  • 44
    • 33646351086 scopus 로고    scopus 로고
    • Adult rats prenatally exposed to ethanol have increased gluconeogenesis and impaired insulin response of hepatic gluconeogenic genes
    • Yao XH, Chen L, Nyomba BL. Adult rats prenatally exposed to ethanol have increased gluconeogenesis and impaired insulin response of hepatic gluconeogenic genes. J Appl Physiol 100: 642-648, 2006.
    • (2006) J Appl Physiol , vol.100 , pp. 642-648
    • Yao, X.H.1    Chen, L.2    Nyomba, B.L.3
  • 45
    • 34248155673 scopus 로고    scopus 로고
    • Abnormal glucose homeostasis in adult female rat offspring after intrauterine ethanol exposure
    • Yao XH, Nyomba BL. Abnormal glucose homeostasis in adult female rat offspring after intrauterine ethanol exposure. Am J Physiol Regul Integr Comp Physiol 292: R1926-R1933, 2007.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Yao, X.H.1    Nyomba, B.L.2
  • 46
    • 0041822087 scopus 로고    scopus 로고
    • Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver
    • Yeon JE, Califano S, Xu J, Wands JR, de la Monte SM. Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver. Hepatology 38: 703-714, 2003.
    • (2003) Hepatology , vol.38 , pp. 703-714
    • Yeon, J.E.1    Califano, S.2    Xu, J.3    Wands, J.R.4    de la Monte, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.