-
1
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick, S. C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170: 827-845.
-
(1989)
J. Exp. Med
, vol.170
, pp. 827-845
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
Hewick, R.M.4
Clark, S.C.5
Chan, S.6
Loudon, R.7
Sherman, F.8
Perussia, B.9
Trinchieri, G.10
-
2
-
-
0029014952
-
+ T cells
-
+ T cells. J. Immunol. 154: 5071-5079.
-
(1995)
J. Immunol
, vol.154
, pp. 5071-5079
-
-
Macatonia, S.E.1
Hosken, N.A.2
Litton, M.3
Vieira, P.4
Hsieh, C.S.5
Culpcpper, J.A.6
Wysocka, M.7
Trinchieri, G.8
Murphy, K.M.9
O'Garra, A.10
-
3
-
-
0025028960
-
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-Jymphoblastoid cells
-
Stern, A. S., F. J. Podlaski, J. D. Hulmes, Y. C. Pan, P. M. Quinn, A. G. Wolitzky, P. C. Familletti, D. L. Stremlo, T. Truitt, R. Chizzonite, et al. 1990. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-Jymphoblastoid cells. Proc. Natl. Acad. Sci. USA 87: 6808-6812.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6808-6812
-
-
Stern, A.S.1
Podlaski, F.J.2
Hulmes, J.D.3
Pan, Y.C.4
Quinn, P.M.5
Wolitzky, A.G.6
Familletti, P.C.7
Stremlo, D.L.8
Truitt, T.9
Chizzonite, R.10
-
4
-
-
0036089285
-
Inflammatory cytokines and antigen presenting cell activation
-
Murtaugh, M. P., and D. L. Foss. 2002. Inflammatory cytokines and antigen presenting cell activation. Vet. Immunol. Immunopathol. 87: 109-121.
-
(2002)
Vet. Immunol. Immunopathol
, vol.87
, pp. 109-121
-
-
Murtaugh, M.P.1
Foss, D.L.2
-
5
-
-
0025875022
-
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
-
Wolf, S. F., P. A. Temple, M. Kobayashi, D. Young, M. Dicig, L. Lowe, R. Dzialo, L. Fitz, C. Ferenz, R. M. Hewick, et al. 1991. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J. Immunol. 146: 3074-3081.
-
(1991)
J. Immunol
, vol.146
, pp. 3074-3081
-
-
Wolf, S.F.1
Temple, P.A.2
Kobayashi, M.3
Young, D.4
Dicig, M.5
Lowe, L.6
Dzialo, R.7
Fitz, L.8
Ferenz, C.9
Hewick, R.M.10
-
6
-
-
0026588207
-
Cloning and expression of murine IL-12
-
Schoenhaut, D. S., A. O. Chua, A. G. Wolitzky, P. M. Quinn, C. M. Dwyer, W. McComas, P. C. Familletti, M. K. Gately, and U. Gubler. 1992. Cloning and expression of murine IL-12. J. Immunol. 148: 3433-3440.
-
(1992)
J. Immunol
, vol.148
, pp. 3433-3440
-
-
Schoenhaut, D.S.1
Chua, A.O.2
Wolitzky, A.G.3
Quinn, P.M.4
Dwyer, C.M.5
McComas, W.6
Familletti, P.C.7
Gately, M.K.8
Gubler, U.9
-
7
-
-
0030884276
-
Immu-nomodulatory functions and molecular regulation of IL-12
-
Ma, X., M. Aste-Amezaga, G. Gri, F. Gerosa, and G. Trinchieri. 1997. Immu-nomodulatory functions and molecular regulation of IL-12. Chem. Immunol. 68: 1-22.
-
(1997)
Chem. Immunol
, vol.68
, pp. 1-22
-
-
Ma, X.1
Aste-Amezaga, M.2
Gri, G.3
Gerosa, F.4
Trinchieri, G.5
-
8
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., N. Ghilardi, M. H. Xie, F. J. de Sauvage, and A. L. Gumey. 2003. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278: 1910-1914.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
de Sauvage, F.J.4
Gumey, A.L.5
-
9
-
-
0033638507
-
Novel pl9 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann, B., R. Lesley, B. Blom, J. C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, K. Singh, et al. 2000. Novel pl9 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13: 715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, K.10
-
10
-
-
14744284737
-
IL-23 up-regulates IL-I0 and induces IL-17 synthesis by polyclonally activated naive T cells in human
-
Vanden Eijnden, S., S. Goriely, D. De Wit, F. Willems, and M. Goldman. 2005. IL-23 up-regulates IL-I0 and induces IL-17 synthesis by polyclonally activated naive T cells in human. Eur. J. Immunol. 35: 469-475.
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 469-475
-
-
Vanden Eijnden, S.1
Goriely, S.2
De Wit, D.3
Willems, F.4
Goldman, M.5
-
11
-
-
0026701132
-
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mono-nuclear cells
-
D'Andrea, A., M. Rengaraju, N. M. Valiante, J. Chehimi, M. Kubin, M. Aste, S. H. Chan, M. Kobayashi, D. Young, E. Nickbarg, et al. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mono-nuclear cells. J. Exp. Med. 176: 1387-1398.
-
(1992)
J. Exp. Med
, vol.176
, pp. 1387-1398
-
-
D'Andrea, A.1
Rengaraju, M.2
Valiante, N.M.3
Chehimi, J.4
Kubin, M.5
Aste, M.6
Chan, S.H.7
Kobayashi, M.8
Young, D.9
Nickbarg, E.10
-
12
-
-
0026559308
-
Molecular characterization of interleukin 12
-
Podlaski, F. J., V. B. Nanduri, J. D. Hulmes, Y. C. Pan, W. Levin, W. Danho, R. Chizzonite, M. K. Gately, and A. S. Stem. 1992. Molecular characterization of interleukin 12. Arch. Biochem. Biophys. 294: 230-237.
-
(1992)
Arch. Biochem. Biophys
, vol.294
, pp. 230-237
-
-
Podlaski, F.J.1
Nanduri, V.B.2
Hulmes, J.D.3
Pan, Y.C.4
Levin, W.5
Danho, W.6
Chizzonite, R.7
Gately, M.K.8
Stem, A.S.9
-
13
-
-
0028967287
-
Mouse interleu-kin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist
-
Gillessen, S., D. Carvajal, P. Ling, F. J. Podlaski, D. L. Stremlo, P. C. Familletti, U. Gubler, D. H. Presky, A. S. Stern, and M. K. Gately. 1995. Mouse interleu-kin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist. Eur. J. Immunol. 25: 200-206.
-
(1995)
Eur. J. Immunol
, vol.25
, pp. 200-206
-
-
Gillessen, S.1
Carvajal, D.2
Ling, P.3
Podlaski, F.J.4
Stremlo, D.L.5
Familletti, P.C.6
Gubler, U.7
Presky, D.H.8
Stern, A.S.9
Gately, M.K.10
-
14
-
-
16344371747
-
Enhancement of interleukin-12 gene-based tumor immunolherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor
-
Jin, H. T., J. I. Youn, H. J. Kim, J. B. Lee, S. J. Ha, J. S. Koh, and Y. C. Sung. 2005. Enhancement of interleukin-12 gene-based tumor immunolherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor. Hum. Gene Ther. 16: 328-338.
-
(2005)
Hum. Gene Ther
, vol.16
, pp. 328-338
-
-
Jin, H.T.1
Youn, J.I.2
Kim, H.J.3
Lee, J.B.4
Ha, S.J.5
Koh, J.S.6
Sung, Y.C.7
-
15
-
-
0033490502
-
Interleukin-12: A cytokine at the interface of inflammation and immunity
-
Trinchieri, G. 1998. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv. Immunol. 70: 83-243.
-
(1998)
Adv. Immunol
, vol.70
, pp. 83-243
-
-
Trinchieri, G.1
-
16
-
-
0031132212
-
In vivo production and function of IL-12 p40 homodimers
-
Heinzel, F. P., A. M. Hujer, F. N. Ahmed, and R. M. Rerko. 1997. In vivo production and function of IL-12 p40 homodimers. J. Immunol. 158: 4381-4388.
-
(1997)
J. Immunol
, vol.158
, pp. 4381-4388
-
-
Heinzel, F.P.1
Hujer, A.M.2
Ahmed, F.N.3
Rerko, R.M.4
-
17
-
-
0028819316
-
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
-
Ling, P., M. K. Gately, U. Gubler, A. S. Stern, P. Lin, K. Hollfelder, C. Su, Y. C. Pan, and J. Hakimi. 1995. Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. J. Immunol. 154: 116-127.
-
(1995)
J. Immunol
, vol.154
, pp. 116-127
-
-
Ling, P.1
Gately, M.K.2
Gubler, U.3
Stern, A.S.4
Lin, P.5
Hollfelder, K.6
Su, C.7
Pan, Y.C.8
Hakimi, J.9
-
18
-
-
0027200981
-
The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer
-
Mattner, F., S. Fischer, S. Guckes, S. Jin, H. Kaulen, E. Schmitt, E. Rude, and T. Germann. 1993. The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer. Eur. J. Immunol. 23: 2202-2208.
-
(1993)
Eur. J. Immunol
, vol.23
, pp. 2202-2208
-
-
Mattner, F.1
Fischer, S.2
Guckes, S.3
Jin, S.4
Kaulen, H.5
Schmitt, E.6
Rude, E.7
Germann, T.8
-
19
-
-
17544399131
-
Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo
-
Gately, M. K., D. M. Carvajal, S. E. Connaughton, S. Gillessen, R. R. Warner, K. D. Kolinsky, V. L. Wilkinson, C. M. Dwyer, G. F. Higgins, Jr., F. J. Podlaski, et al. 1996. Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo. Ann. NY Acad. Sci. 795: 1-12.
-
(1996)
Ann. NY Acad. Sci
, vol.795
, pp. 1-12
-
-
Gately, M.K.1
Carvajal, D.M.2
Connaughton, S.E.3
Gillessen, S.4
Warner, R.R.5
Kolinsky, K.D.6
Wilkinson, V.L.7
Dwyer, C.M.8
Higgins Jr., G.F.9
Podlaski, F.J.10
-
20
-
-
33644830150
-
The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects
-
Shimozato, O., S. Ugai, M. Chiyo, H. Takenobu, H. Nagakawa, A. Wada, K. Kawamura, H. Yamamoto, and M. Tagawa. 2006. The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects. Immunology 117: 22-28.
-
(2006)
Immunology
, vol.117
, pp. 22-28
-
-
Shimozato, O.1
Ugai, S.2
Chiyo, M.3
Takenobu, H.4
Nagakawa, H.5
Wada, A.6
Kawamura, K.7
Yamamoto, H.8
Tagawa, M.9
-
21
-
-
0029808332
-
Local production of the p40 subunit of interleukin 12 sup-presses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection
-
Kato, K., O. Shimozato, K. Hoshi, H. Wakimoto, II. Hamada, H. Yagita, and K. Okumura. 1996. Local production of the p40 subunit of interleukin 12 sup-presses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection. Proc. Natl. Acad. Sci. USA 93: 9085-9089.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9085-9089
-
-
Kato, K.O.1
Shimozato2
Hoshi, K.3
Wakimoto II, H.4
Hamada5
Yagita, H.6
Okumura, K.7
-
22
-
-
0031255064
-
CTL generation in the presence of lL-4 is inhibited by free p40: Evidence for early and late IL-12 function
-
Abdi, K., and S. H. Herrmann. 1997. CTL generation in the presence of lL-4 is inhibited by free p40: evidence for early and late IL-12 function. J. Immunol. 159: 3148-3155.
-
(1997)
J. Immunol
, vol.159
, pp. 3148-3155
-
-
Abdi, K.1
Herrmann, S.H.2
-
23
-
-
0031964713
-
Reduced T helper 1 responses in IL-12 p40 transgenic mice
-
Yoshimoto, T., C. R. Wang, T. Yoneto, S. Waki, S. Sunaga, Y. Komagata, M. Mitsuyama, J. Miyazaki, and H. Nariuchi. 1998. Reduced T helper 1 responses in IL-12 p40 transgenic mice. J. Immunol. 160: 588-594.
-
(1998)
J. Immunol
, vol.160
, pp. 588-594
-
-
Yoshimoto, T.1
Wang, C.R.2
Yoneto, T.3
Waki, S.4
Sunaga, S.5
Komagata, Y.6
Mitsuyama, M.7
Miyazaki, J.8
Nariuchi, H.9
-
24
-
-
0031178963
-
Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer
-
Chen, L., D. Chen, E. Block, M. O'Donnell, D. W. Kufe, and S. K. Clinton. 1997. Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer. J. Immunol. 159: 351-359.
-
(1997)
J. Immunol
, vol.159
, pp. 351-359
-
-
Chen, L.1
Chen, D.2
Block, E.3
O'Donnell, M.4
Kufe, D.W.5
Clinton, S.K.6
-
25
-
-
0036218351
-
Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization
-
Ha, S. J., J. Chang, M. K. Song, Y. S. Suh, H. T. Jin, C. H. Lee, G. H. Nam, G. Choi, K. Y. Choi, S. H. Lee, et al. 2002. Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization. Nat. Biotechnol. 20: 381-386.
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 381-386
-
-
Ha, S.J.1
Chang, J.2
Song, M.K.3
Suh, Y.S.4
Jin, H.T.5
Lee, C.H.6
Nam, G.H.7
Choi, G.8
Choi, K.Y.9
Lee, S.H.10
-
26
-
-
0030240073
-
IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection: Evidence against a dominant protective role for T helper 2 cytokines in alloimmunity
-
Piccotti, J. R., S. Y. Chan, R. E. Goodman, J. Magram, E. J. Eichwald, and D. K. Bishop. 1996. IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection: evidence against a dominant protective role for T helper 2 cytokines in alloimmunity. J. Immunol. 157: 1951-1957.
-
(1996)
J. Immunol
, vol.157
, pp. 1951-1957
-
-
Piccotti, J.R.1
Chan, S.Y.2
Goodman, R.E.3
Magram, J.4
Eichwald, E.J.5
Bishop, D.K.6
-
28
-
-
0000155803
-
A novel function of IL-12p40 as a chemotactic molecule for macrophages
-
Ha, S. J., C. H. Lee, S. B. Lee, C. M. Kim, K. L. Jang. H. S. Shin, and Y. C. Sung. 1999. A novel function of IL-12p40 as a chemotactic molecule for macrophages. J. Immunol. 163: 2902-2908.
-
(1999)
J. Immunol
, vol.163
, pp. 2902-2908
-
-
Ha, S.J.1
Lee, C.H.2
Lee, S.B.3
Kim, C.M.4
Jang, K.L.5
Shin, H.S.6
Sung, Y.C.7
-
29
-
-
0035892749
-
A protective and agonistic function of IL-12p40 in myco-bacterial infection
-
Holscher, C., R. A. Atkinson, B. Arendse, N. Brown, E. Myburgh, G. Alber, and F. Brombacher. 2001. A protective and agonistic function of IL-12p40 in myco-bacterial infection. J. Immunol. 167: 6957-6966.
-
(2001)
J. Immunol
, vol.167
, pp. 6957-6966
-
-
Holscher, C.1
Atkinson, R.A.2
Arendse, B.3
Brown, N.4
Myburgh, E.5
Alber, G.6
Brombacher, F.7
-
30
-
-
33745812070
-
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
-
Khader, S. A., S. Partida-Sanchez, G. Bell, D. M. Jelley-Gibbs, S. Swain, J. E. Pearl, N. Ghilardi, F. J. Dcsauvage, F. E. Lund, and A. M. Cooper. 2006. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J. Exp. Med. 203: 1805-1815.
-
(2006)
J. Exp. Med
, vol.203
, pp. 1805-1815
-
-
Khader, S.A.1
Partida-Sanchez, S.2
Bell, G.3
Jelley-Gibbs, D.M.4
Swain, S.5
Pearl, J.E.6
Ghilardi, N.7
Dcsauvage, F.J.8
Lund, F.E.9
Cooper, A.M.10
-
31
-
-
23644432804
-
The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met as a novel adjuvant for DNA vaccine
-
Lee, C. G., S. Y. Choi, S. H. Park, K. S. Park, S. H. Ryu, and Y. C. Sung. 2005. The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met as a novel adjuvant for DNA vaccine. Vaccine 23: 4703-4710.
-
(2005)
Vaccine
, vol.23
, pp. 4703-4710
-
-
Lee, C.G.1
Choi, S.Y.2
Park, S.H.3
Park, K.S.4
Ryu, S.H.5
Sung, Y.C.6
-
32
-
-
0033136294
-
Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: The role of nitric oxide
-
Lasarte, J. J., F. J. Corrales, N. Casares, A. Lopez-Diaz de Cerio, C. Qian, X. Xie, F. Borras-Cuesta, and J. Prieto. 1999. Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide. J. Immunol. 162: 5270-5277.
-
(1999)
J. Immunol
, vol.162
, pp. 5270-5277
-
-
Lasarte, J.J.1
Corrales, F.J.2
Casares, N.3
Lopez-Diaz de Cerio, A.4
Qian, C.5
Xie, X.6
Borras-Cuesta, F.7
Prieto, J.8
-
33
-
-
0032476615
-
Immune suppression by recombinant interleukin (rIL)-12 involves in-terferon γ induction of nitric oxide synthase 2 (iNOS) activity: Inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect
-
Koblish, H. K., C. A. Hunter, M. Wysocka, G. Trinchieri, and W. M. Lee. 1998. Immune suppression by recombinant interleukin (rIL)-12 involves in-terferon γ induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect. J. Exp. Med. 188: 1603-1610.
-
(1998)
J. Exp. Med
, vol.188
, pp. 1603-1610
-
-
Koblish, H.K.1
Hunter, C.A.2
Wysocka, M.3
Trinchieri, G.4
Lee, W.M.5
-
34
-
-
0029116336
-
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
-
Bacon, C. M., E. F. Petricoin, III, J. R. Ortaldo, R. C. Rees, A. C. Lamer, J. A. Johnston, and J. J. O'Shea. 1995. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc, Natl. Acad. Sci. USA 92: 7307-7311.
-
(1995)
Proc, Natl. Acad. Sci. USA
, vol.92
, pp. 7307-7311
-
-
Bacon, C.M.1
Petricoin III, E.F.2
Ortaldo, J.R.3
Rees, R.C.4
Lamer, A.C.5
Johnston, J.A.6
O'Shea, J.J.7
-
35
-
-
0028943484
-
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat) 3 and Stat4
-
Jacobson, N. G., S. J. Szabo, R. M. Weber-Nordt, Z. Zhong, R. D. Schreiber, J. E. Darnell, Jr., and K. M. Murphy. 1995. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat) 3 and Stat4. J. Exp. Med. 181: 1755-1762.
-
(1995)
J. Exp. Med
, vol.181
, pp. 1755-1762
-
-
Jacobson, N.G.1
Szabo, S.J.2
Weber-Nordt, R.M.3
Zhong, Z.4
Schreiber, R.D.5
Darnell Jr., J.E.6
Murphy, K.M.7
-
36
-
-
0031571205
-
Characterization of IL-12 receptor β1 chain (IL-I2Rβ1)-deficient mice: IL-12RβI is an essential component of the functional mouse IL-12 receptor
-
Wu, C., J. Ferrante, M. K. Gately, and J. Magram. 1997. Characterization of IL-12 receptor β1 chain (IL-I2Rβ1)-deficient mice: IL-12RβI is an essential component of the functional mouse IL-12 receptor. J. Immunol. 159: 1658-1665.
-
(1997)
J. Immunol
, vol.159
, pp. 1658-1665
-
-
Wu, C.1
Ferrante, J.2
Gately, M.K.3
Magram, J.4
-
37
-
-
0034541139
-
IL-12 receptor β 2 (IL-12Rβ2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites
-
Wu, C., X. Wang, M. Gadina, J. J. O'Shea, D. H. Presky, and J. Magram. 2000. IL-12 receptor β 2 (IL-12Rβ2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites. J. Immunol. 165: 6221-6228.
-
(2000)
J. Immunol
, vol.165
, pp. 6221-6228
-
-
Wu, C.1
Wang, X.2
Gadina, M.3
O'Shea, J.J.4
Presky, D.H.5
Magram, J.6
-
38
-
-
0020457982
-
Protection against synge-neic lymphoma by a long-lived cytotoxic T-cell clone
-
Dailey, M. O., E. Pillemer, and I. L. Weissman. 1982. Protection against synge-neic lymphoma by a long-lived cytotoxic T-cell clone. Proc. Natl. Acad. Sci. USA 79: 5384-5387.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 5384-5387
-
-
Dailey, M.O.1
Pillemer, E.2
Weissman, I.L.3
-
39
-
-
0022574005
-
+ cells: Cytolytic T cells can mediate eradication of disseminated leukemia
-
+ cells: cytolytic T cells can mediate eradication of disseminated leukemia. J. Immunol. 136: 1917-1922.
-
(1986)
J. Immunol
, vol.136
, pp. 1917-1922
-
-
Greenberg, P.D.1
-
40
-
-
0024466940
-
Eradication of adenovirus El-induced tumors by ElA-specific cytotoxic T lymphocytes
-
Kast, W. M., R. Offringa, P. J. Peters, A. C. Voordouw, R. H. Meloen, A. J. van der Eb, and C. J. Melief. 1989. Eradication of adenovirus El-induced tumors by ElA-specific cytotoxic T lymphocytes. Cell 59: 603-614.
-
(1989)
Cell
, vol.59
, pp. 603-614
-
-
Kast, W.M.1
Offringa, R.2
Peters, P.J.3
Voordouw, A.C.4
Meloen, R.H.5
van der Eb, A.J.6
Melief, C.J.7
-
41
-
-
0032168336
-
-
Grohmann, U., M. L.' Belladonna, R. Bianchi, C. Orabona, E. Ayroldi, M. C. Fioretti, and P. Puccetti. 1998. IL-12 acts directly on DC to promote nuclear localization of NF-κB and primes DC for IL-12 production. Immunity 9: 315-323.
-
Grohmann, U., M. L.' Belladonna, R. Bianchi, C. Orabona, E. Ayroldi, M. C. Fioretti, and P. Puccetti. 1998. IL-12 acts directly on DC to promote nuclear localization of NF-κB and primes DC for IL-12 production. Immunity 9: 315-323.
-
-
-
-
42
-
-
0031711866
-
Rapid recruitment of macrophages in interleukin-12-mediated tumour regression
-
Ha, S. J., S. B. Lee, C. M. Kim, H. S. Shin, and Y. C. Sung. 1998. Rapid recruitment of macrophages in interleukin-12-mediated tumour regression. Immunology 95: 156-163.
-
(1998)
Immunology
, vol.95
, pp. 156-163
-
-
Ha, S.J.1
Lee, S.B.2
Kim, C.M.3
Shin, H.S.4
Sung, Y.C.5
-
43
-
-
0031253635
-
IL-12 induces IFN-γ expression and secretion in mouse peritoneal macrophages
-
Puddu, P., L. Fantuzzi, P. Borghi, B. Varano, G. Rainaldi, E. Guillemard, W. Malomi, P. Nicaise, S. F. Wolf, F. Belardelli, and S. Gessani. 1997. IL-12 induces IFN-γ expression and secretion in mouse peritoneal macrophages. J. Immunol. 159: 3490-3497.
-
(1997)
J. Immunol
, vol.159
, pp. 3490-3497
-
-
Puddu, P.1
Fantuzzi, L.2
Borghi, P.3
Varano, B.4
Rainaldi, G.5
Guillemard, E.6
Malomi, W.7
Nicaise, P.8
Wolf, S.F.9
Belardelli, F.10
Gessani, S.11
-
44
-
-
0345735824
-
IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor β1
-
Russell, T. D., Q. Yan, G. Fan, A. P. Khalifah, D. K. Bishop, S. L. Brody, and M. J. Walter. 2003. IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor β1. J. Immunol. 171:6866-6874.
-
(2003)
J. Immunol
, vol.171
, pp. 6866-6874
-
-
Russell, T.D.1
Yan, Q.2
Fan, G.3
Khalifah, A.P.4
Bishop, D.K.5
Brody, S.L.6
Walter, M.J.7
-
45
-
-
0028235663
-
Expression cloning of a human IL-12 receptor component: A new member of the cytokine receptor superfamily with strong homology to gp 130
-
Chua, A. O., R. Chizzonite, B. B. Desai, T. P. Truitl, P. Nunes, L. J. Minetti, R. R. Warrier, D. H. Presky, J. F. Levine, M. K. Galely, et al. 1994. Expression cloning of a human IL-12 receptor component: a new member of the cytokine receptor superfamily with strong homology to gp 130. J. Immunol. 153: 128-136.
-
(1994)
J. Immunol
, vol.153
, pp. 128-136
-
-
Chua, A.O.1
Chizzonite, R.2
Desai, B.B.3
Truitl, T.P.4
Nunes, P.5
Minetti, L.J.6
Warrier, R.R.7
Presky, D.H.8
Levine, J.F.9
Galely, M.K.10
-
46
-
-
0030063347
-
IL-12 expression in AIDS-related lymphoma B cell lines
-
Benjamin, D., V. Sharma, M. Kubin, J. L. Klein, A. Sartori, J. Holliday, and G. Trinchieri. 1996. IL-12 expression in AIDS-related lymphoma B cell lines. J. Immunol. 156: 1626-1637.
-
(1996)
J. Immunol
, vol.156
, pp. 1626-1637
-
-
Benjamin, D.1
Sharma, V.2
Kubin, M.3
Klein, J.L.4
Sartori, A.5
Holliday, J.6
Trinchieri, G.7
-
47
-
-
0030459681
-
Direct binding of IL-12 to human and murine B lymphocytes
-
Vogel, L. A., L. C. Showe, T. L. Lester, R. M. McNutt, V. H. Van Cleave, and D. W. Metzger. 1996. Direct binding of IL-12 to human and murine B lymphocytes. Int. Immunol. 8: 1955-1962.
-
(1996)
Int. Immunol
, vol.8
, pp. 1955-1962
-
-
Vogel, L.A.1
Showe, L.C.2
Lester, T.L.3
McNutt, R.M.4
Van Cleave, V.H.5
Metzger, D.W.6
-
48
-
-
1842387765
-
Biological function and distribution of human interleukin-12 receptor β chain
-
Wu, C. Y., R. R. Warrier, D. M. Carvajal, A. O. Chua, L. J. Minetti, R. Chizzonite, P. K. Mongini, A. S. Stern, U. Gubler, D. H. Presky, and M. K. Gately. 1996. Biological function and distribution of human interleukin-12 receptor β chain. Eur. J. Immunol. 26: 345-350.
-
(1996)
Eur. J. Immunol
, vol.26
, pp. 345-350
-
-
Wu, C.Y.1
Warrier, R.R.2
Carvajal, D.M.3
Chua, A.O.4
Minetti, L.J.5
Chizzonite, R.6
Mongini, P.K.7
Stern, A.S.8
Gubler, U.9
Presky, D.H.10
Gately, M.K.11
-
49
-
-
0030010569
-
Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-α
-
Yu, C. R., J. X. Lin, D. W. Fink, S. Akira, E. T. Bloom, and A. Yamauchi. 1996. Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-α. J. Immunol. 157: 126-137.
-
(1996)
J. Immunol
, vol.157
, pp. 126-137
-
-
Yu, C.R.1
Lin, J.X.2
Fink, D.W.3
Akira, S.4
Bloom, E.T.5
Yamauchi, A.6
-
50
-
-
0037479043
-
Induction of tumor necrosis faclor-α (TNF-α) by interleukin-12 p40 monomer and homodimer in microglia and macrophages
-
Jana, M., S. Dasgupta, R. N. Saha, X. Liu, and K. Pahan. 2003. Induction of tumor necrosis faclor-α (TNF-α) by interleukin-12 p40 monomer and homodimer in microglia and macrophages. J. Neurochem. 86: 519-528.
-
(2003)
J. Neurochem
, vol.86
, pp. 519-528
-
-
Jana, M.1
Dasgupta, S.2
Saha, R.N.3
Liu, X.4
Pahan, K.5
-
51
-
-
0035896521
-
Induction of nitric-oxide synthase and activation of NF-κB by interleukin-12 p40 in microglial cells
-
Pahan, K., F. G. Sheikh, X. Liu, S. Hilger, M. McKinney, and T. M. Petro. 2001. Induction of nitric-oxide synthase and activation of NF-κB by interleukin-12 p40 in microglial cells. J. Biol. Chem. 276: 7899-7905.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 7899-7905
-
-
Pahan, K.1
Sheikh, F.G.2
Liu, X.3
Hilger, S.4
McKinney, M.5
Petro, T.M.6
-
52
-
-
0346734181
-
IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization
-
Ha, S. J., D. J. Kim, K. H. Back, Y. D. Yun, and Y. C. Sung. 2004. IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization. J. Immunol. 172: 525-531.
-
(2004)
J. Immunol
, vol.172
, pp. 525-531
-
-
Ha, S.J.1
Kim, D.J.2
Back, K.H.3
Yun, Y.D.4
Sung, Y.C.5
-
53
-
-
33646417072
-
The IL-23/IL-17 axis in inflammation
-
Iwakura, Y., and H. Ishigame. 2006. The IL-23/IL-17 axis in inflammation. J. Clin. Invest. 116: 1218-1222.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1218-1222
-
-
Iwakura, Y.1
Ishigame, H.2
-
54
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
-
Parham, C., M. Chirica, J. Timans, E. Vaisberg, M. Travis, J. Cheung, S. Pflanz, R. Zhang, K. P. Singh, F. Vega, et al. 2002. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R. J. Immunol. 168: 5699-5708.
-
(2002)
J. Immunol
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.P.9
Vega, F.10
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