Direct binding of IL-12 to human and murine B lymphocytes

International Immunology

Volumn 8, Issue 12, 1996, Pages 1955-1962

  Vogel, Laura A ^c   Showe, Louise C ^b   Lester, Terry L ^a   McNutt, Renee M ^a   Van Cleave, Victor H ^a,d   Metzger, Dennis W ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b WISTAR INSTITUTE   (United States)

^c PFIZER INC   (United States)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

B lymphocytes; B 1 lymphocytes; Cytokine receptors; IL 12

Indexed keywords

INTERLEUKIN 12;

ANIMAL CELL; ARTICLE; B LYMPHOBLAST; B LYMPHOCYTE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOMA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN LYMPHOCYTE; T LYMPHOBLAST;

ANIMALS; B-LYMPHOCYTES; BURKITT LYMPHOMA; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-12; MICE; MICE, INBRED BALB C; PROTEIN BINDING; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; TUMOR CELLS, CULTURED;

EID: 0030459681     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.12.1955     Document Type: Article

References (38)

1. Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
2. Buchanan, J. M., Humphrey, G. B. and Metzger, D. W. 1996. Biological activity and potential therapeutic applications of interleukin-12. Int. J. Pediat. Hematol. Oncol. 3:123.
3. Hendrzak, J. A. and Brunda, M. J. 1995. Interleukin-12: biologic activity, therapeutic utility, and role in disease. Lab. Invest. 72:619.
4. McKnight, A. J., Zimmer, G. J., Fogelman, I., Wolf, S. F. and Abbas, A. K. 1994. Effects of IL-12 on helper T cell-dependent immune responses in vivo. J. Immunol. 152:2172.
5. Morris, S. C., Madden, K. B., Adamovicz, J. J., Gause, W. C., Hubbard, B. R., Gately, M. K. and Finkelman, F. D. 1994. Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection. J. Immunol. 152:1047.
6. Buchanan, J. M., Vbgel, L. A., Van Cleave, V. H. and Metzger, D. W. 1995. Interleukin-12 alters the isotype-restricted antibody response of mice to hen eggwhite lysozyme. Int. Immunol. 7:1519.
7. Germann, T., Bongartz, M., Dlugonska, H., Hess, H., Schmitt, E., Kolbe, L., Kolsch, E., Podlaski, F. J., Gately, M. K. and Rude, E. 1995. Interleukin-12 profoundly up-regulates the synthesis of antigen-specific complement-fixing lgG2a, lgG2b, and IgG3 antibody subclasses in vivo. Eur J. Immunol. 25:823.
8. Metzger, D. W., Buchanan, J. M., Collins, J. L., Lester, T. L., Murray, K. S., Van Cleave, V. H., Vogel, L. A. and Dunnick, W. A. 1995. Enhancement of humoral immunity by IL-12. Ann. NY Acad. Sci., in press.
9. Vogel, L. A., Lester, T L., Van Cleave, V. H. and Metzger, D. W. 1996. Inhibition of murine B-1 lymphocytes by interleukin-12. Eur. J. Immunol. 26:219.
10. Desai, B. B., Quinn, P. M., Wolitzky, A. G., Mongini, P. K. A., Chizzonite, R. and Gately, M. K. 1992, IL-12R. II. Distribution and regulation of receptor expression. J. Immunol. 148:3125.
11. Finkelman, F. D., Katona, I. M., Mosmann, T. R. and Coffman, R. L. 1988. IFN-γ regulates the isotypes of Ig secreted during in vivo humoral immune responses. J. Immunol. 140:1022.
12. Snapper, C. M. and Paul, W. E. 1987. Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944.
13. Snapper, C. M., Peschel, C. and Paul, W. E. 1988. IFN-γ stimulates lgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide. J. Immunol. 140:2121.
14. + and conventional B cells. Sensitivity to LPS-induced differentiation and interferon-γ-mediated inhibition of differentiation. Clin. Immunol. Immunopathol. 68:327.
15. Vezzio, N., Gately, M., Kiniwa, M., Wu, C. Y. and Delespesse, G. 1993. IFN-γ-independent suppression of IgE synthesis by IL-12. J. Immunol. 150:61A (Abstr.).
16. Jelinek, D. F. and Braaten, J. K. 1995. Role of IL-12 in human B lymphocyte proliferation and differentiation. J. Immunol. 154:1606.
17. Wu, C. Y., Warrier, R. R., Carvajal, D. M., Chua, A. O., Minetti, L. J., Chizzonite, R., Mongini, P. K. A., Stern, A. S., Gubler, U., Presky, D. H. and Gately, M. K. 1996. Biological function and distribution of human interleukin-12 receptor β chain. Eur. J. Immunol. 26:345.
18. Rao, M., Lee, W. T. and Conrad, D. H. 1987. Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE. J. Immunol. 138:1845.
19. Coffman, R. L and Weissman, I. L. 1981. B220: a B cell-specific member of the T200 glycoprotein family. Nature 289:681.
20. Unkeless, J. C. 1979. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580.
21. Ledbetter, J. A. and Herzenberg, L. A. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:63.
22. Springer, T., Galfre, G., Secher, D. S. and Milstein, C. 1978. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8:539.
23. Vogel, L. A., Sercarz, E. E. and Metzger, D. W. 1995. Antibody response of murine B-1 cells to hen eggwhite lysozyme. Cell. Immunol. 161:88.
24. Hunter, C. A., Subauste, C. S., Van Cleave, V. H. and Remington, J. S. 1994. Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect. Immun. 62:2818.
25. Gately, M. K., Warrier, R. R., Honasoge, S., Carvajal, D. M., Faherty, D. A., Connaughton, S. E., Anderson, T. D., Sarmiento, U., Hubbard, B. R. and Murphy, M. 1994. Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo. Int. Immunol. 6:157.
26. Gilman, M. 1996. Ribonuclease protection assay. In Ausubel, F. M., Biert, R., Kingston, R. E., Moore, D. D., Siedman, J. G., Smith, J. A. and Struhl, K., eds, Current Protocols in Molecular Biology, John Wiley & Sons, New York, p. 4.7.1.
27. Showe, L. C., Wysocka, M., Wang, B., Lineman-Williams, D., Peritt, D., Showe, M. K. and Trinchieri, G. 1996. Structure of the mouse IL-12Rβ1 chain and regulation of its expression in BCG/LPS treated mice. Ann. NY Acad. Sci., in press.
28. Merberg, D. M., Wolf, S. F. and Clark, S. C. 1992. Sequence similarity between NKSF and the IL-6/G-CSF family, Immunol. Today 13:77.
29. Maruo, S., Toyo-Oka, K., Oh-Hora, M., Tai, X. G., Iwata, H., Takenaka, H., Yamada, S., Ono, S., Hamaoka, T., Kobayashi, M., Wysocka, M., Trinchieri, G. and Fujiwara, H. 1996. IL-12 produced by antigen-presenting cells induces IL-2-independent proliferation of T helper cell clones. J. Immunol. 156:1748.
30. Chua, A. O., Wilkinson, V. L. Presky, D. H. and Gubler, U. 1995. Cloning and characterization of a mouse IL-12 receptor-β component. J. Immunol. 155:4286.
31. Benjamin, D., Sharma, V., Kubin, M., Klein, J. L., Sartori, A., Holliday, J. and Trinchieri, G. 1996. IL-12 expression in AIDS-related lymphoma B cell lines. J. Immunol. 156:1626.
32. Germann, T., Guckes, S., Bongartz, M., Dlugonska, H., Schmitt, E., Kolbe, L., Kolsch, E., Podlaski, F. J., Gately, M. K. and Rude, E. 1995. Administration of IL-12 during ongoing immune responses fails to permanently suppress and can even enhance the synthesis of antigen-specific IgE. Int. Immunol. 7:1649.
33. + cell populations in mice infected with Leishmania major. 9th Int. Congress Immunol. 894 (Abstr.).
34. D'Andrea, A., Rengaraju, M., Valiante, N. M., Chehimi, J., Kubin, M., Aste, M., Chan, S. H., Kobayashi, M., Young, D., Nickbarg, E. B., Chizzonite, R., Wolf, S. F. and Trinchieri, G. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J. Exp. Med. 176:1387.
35. Mengel, J., Dare, L., Dare, G. M., Delgado, M., Nomizo, A., Silva, J. S. and Campos-Neto, A. 1992. An activated murine B cell lymphoma line (A-20) produces a factor-like activity which is functionally related to human natural killer cell stimulatory factor. Eur. J. Immunol. 22:3173.
36. Mosmann, T. R. and Coffman, R. L. 1989. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv. Immunol. 46:111.
37. O'Garra, A., Chang, R., Go, N., Hastings, R., Haughton, G. and Howard, M. 1992. Ly-1 B (B-1) cells are the main source of B cell-derived interleukin 10. Eur. J. Immunol. 22:711.
38. D'Andrea, A., Aste-Amezaga, M., Valiante, N, M., Ma, X., Kubin, M. and Trinchieri, G. 1993. Interleukin-10 inhibits human lymphocyte IFN-γ production by suppressing natural killer cell stimulatory factor/interleukin-12 synthesis in accessory cells. J. Exp. Med. 178:1041.