-
1
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick. S. C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170:827.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 827
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
Hewick, R.M.4
Clark, S.C.5
Chan, S.6
Loudon, R.7
Sherman, F.8
Perussia, B.9
Trinchieri, G.10
-
2
-
-
0025028960
-
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
-
Stern, A. S., F. J. Podlaski, J. D. Hulmes, Y. C. Pan, P. M. Quinn, A. G. Wolitzky, P. C. Familletti, D. L. Stremlo, T. Truitt, R. Chizzonite, and M. K. Gately. 1990. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 87:6808.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6808
-
-
Stern, A.S.1
Podlaski, F.J.2
Hulmes, J.D.3
Pan, Y.C.4
Quinn, P.M.5
Wolitzky, A.G.6
Familletti, P.C.7
Stremlo, D.L.8
Truitt, T.9
Chizzonite, R.10
Gately, M.K.11
-
3
-
-
0026701132
-
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mono-nuclear cells
-
D'Andrea, A., M. Rengaraju, N. M. Valiante, J. Chehimi, M. Kubin, M. Aste, S. H. Chan, M. Kobayashi, D. Young, and E. Nickbarg, et al. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mono-nuclear cells. J. Exp. Med. 176:1387.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1387
-
-
D'Andrea, A.1
Rengaraju, M.2
Valiante, N.M.3
Chehimi, J.4
Kubin, M.5
Aste, M.6
Chan, S.H.7
Kobayashi, M.8
Young, D.9
Nickbarg, E.10
-
4
-
-
0029014952
-
+ T cells
-
+ T cells. J. Immunol. 154:5071.
-
(1995)
J. Immunol.
, vol.154
, pp. 5071
-
-
Macatonia, S.E.1
Hosken, N.A.2
Litton, M.3
Vieira, P.4
Hsieh, C.S.5
Culpepper, J.A.6
Wysocka, M.7
Trinchieri, G.8
Murphy, K.M.9
O'Garra, A.10
-
5
-
-
0025808629
-
Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor
-
Gubler, U., A. O. Chua, D. S. Schoenhaut, C. M. Dwyer, W. McComas, R. Motyka, N. Nabavi, A. G. Wolitzky, P. M. Quinn, P. C. Familletti, and M. K. Gately. 1991. Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc. Natl. Acad. Sci. USA 88:4143.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4143
-
-
Gubler, U.1
Chua, A.O.2
Schoenhaut, D.S.3
Dwyer, C.M.4
McComas, W.5
Motyka, R.6
Nabavi, N.7
Wolitzky, A.G.8
Quinn, P.M.9
Familletti, P.C.10
Gately, M.K.11
-
6
-
-
0025873502
-
Regulation of human lymphocyte proliferation by a heterodimeric cytokine. IL-12 (cytotoxic lymphocyte maturation factor)
-
Gately, M. K., B. B. Desai, A. G. Wolitzky, P. M. Quinn, C. M. Dwyer, F. J. Podlaski, P. C. Familletti, F. Sinigaglia, R. Chizonnite, U. Gubler, and A. S. Stern. 1991. Regulation of human lymphocyte proliferation by a heterodimeric cytokine. IL-12 (cytotoxic lymphocyte maturation factor). J. Immunol. 147:874.
-
(1991)
J. Immunol.
, vol.147
, pp. 874
-
-
Gately, M.K.1
Desai, B.B.2
Wolitzky, A.G.3
Quinn, P.M.4
Dwyer, C.M.5
Podlaski, F.J.6
Familletti, P.C.7
Sinigaglia, F.8
Chizonnite, R.9
Gubler, U.10
Stern, A.S.11
-
7
-
-
0025819340
-
Induction of interferon γ production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
-
Chan, S. H., B. Perussia, J. W. Gupta, M. Kobayashi, M. Pospisil, H. A. Young, S. F. Wolf. D. Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon γ production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 869
-
-
Chan, S.H.1
Perussia, B.2
Gupta, J.W.3
Kobayashi, M.4
Pospisil, M.5
Young, H.A.6
Wolf, S.F.7
Young, D.8
Clark, S.C.9
Trinchieri, G.10
-
9
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type I (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
-
Manetti, R., P. Parronchi, M. G. Giudizi, M. P. Piccinni, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type I (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 177:1199.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1199
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
Piccinni, M.P.4
Maggi, E.5
Trinchieri, G.6
Romagnani, S.7
-
10
-
-
0028096083
-
Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo
-
Gately, M. K., R. R. Warrier, S. Honasoge, D. M. Carvajal, D. A. Faherty, S. E. Connaughton, T. D. Anderson, U. Sarmiento, B. R. Hubbard, and M. Murphy. 1994. Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo. Int. Immunol. 6:157.
-
(1994)
Int. Immunol.
, vol.6
, pp. 157
-
-
Gately, M.K.1
Warrier, R.R.2
Honasoge, S.3
Carvajal, D.M.4
Faherty, D.A.5
Connaughton, S.E.6
Anderson, T.D.7
Sarmiento, U.8
Hubbard, B.R.9
Murphy, M.10
-
11
-
-
0026559308
-
Molecular characterization of interleukin 12
-
Podlaski, F. J., V. B. Nanduri, J. D. Hulmes, Y. C. Pan, W. Levin, W. Danho, R. Chizzonite, M. K. Gately, and A. S. Stern. 1992. Molecular characterization of interleukin 12. Arch. Biochem. Biophys. 294:230.
-
(1992)
Arch. Biochem. Biophys.
, vol.294
, pp. 230
-
-
Podlaski, F.J.1
Nanduri, V.B.2
Hulmes, J.D.3
Pan, Y.C.4
Levin, W.5
Danho, W.6
Chizzonite, R.7
Gately, M.K.8
Stern, A.S.9
-
12
-
-
0028967287
-
Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist
-
Gillessen, S., D. Carvajal, P. Ling, F. J. Podlaski, D. L. Stremlo, P. C. Familletti, U. Gubler, D. H. Presky, A. S. Stern, and M. K. Gately. 1995. Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist. Eur. J. Immunol. 25: 200.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 200
-
-
Gillessen, S.1
Carvajal, D.2
Ling, P.3
Podlaski, F.J.4
Stremlo, D.L.5
Familletti, P.C.6
Gubler, U.7
Presky, D.H.8
Stern, A.S.9
Gately, M.K.10
-
13
-
-
0028085437
-
Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of γ interferon
-
Heinzel, F. P., R. M. Rerko, P. Ling, J. Hakimi, and D. S. Schoenhaut. 1994. Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of γ interferon. Infect. Immun. 62:4244.
-
(1994)
Infect. Immun.
, vol.62
, pp. 4244
-
-
Heinzel, F.P.1
Rerko, R.M.2
Ling, P.3
Hakimi, J.4
Schoenhaut, D.S.5
-
14
-
-
0028220266
-
Interleukin 12 at the site of disease in tuberculosis
-
Zhang, M., M. K. Gately, E. Wang, J. Gong, S. F. Wolf, S. Lu, R. L. Modlin, and P. F. Barnes. 1994. Interleukin 12 at the site of disease in tuberculosis. J. Clin. Invest. 93:1733.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1733
-
-
Zhang, M.1
Gately, M.K.2
Wang, E.3
Gong, J.4
Wolf, S.F.5
Lu, S.6
Modlin, R.L.7
Barnes, P.F.8
-
15
-
-
0028987562
-
Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice
-
Wysocka, M., M. Kubin, L. Q. Vieira, L. Ozmen, G. Garotta, P. Scott, and G. Trinchieri. 1995. Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25:672.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 672
-
-
Wysocka, M.1
Kubin, M.2
Vieira, L.Q.3
Ozmen, L.4
Garotta, G.5
Scott, P.6
Trinchieri, G.7
-
16
-
-
0027200981
-
The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer
-
Mattner, F., S. Fischer, S. Guckes, S. Jin, H. Kaulen, E. Schmitt, E. Rude, and T. Germann. 1993. The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer. Eur. J. Immunol. 23:2202.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2202
-
-
Mattner, F.1
Fischer, S.2
Guckes, S.3
Jin, S.4
Kaulen, H.5
Schmitt, E.6
Rude, E.7
Germann, T.8
-
17
-
-
0028819316
-
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
-
Ling, P., M. K. Gately, U. Gubler, A. S. Stern, P. Lin, K. Hollfelder, C. Su, Y. C. Pan, and J. Hakimi. 1995. Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. J. Immunol. 154:116.
-
(1995)
J. Immunol.
, vol.154
, pp. 116
-
-
Ling, P.1
Gately, M.K.2
Gubler, U.3
Stern, A.S.4
Lin, P.5
Hollfelder, K.6
Su, C.7
Pan, Y.C.8
Hakimi, J.9
-
18
-
-
0029808332
-
Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection
-
Kato, K., O. Shimozato, K. Hoshi, H. Wakimoto, H. Hamada, H. Yagita, and K. Okumura. 1996. Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection. Proc. Natl. Acad. Sci. USA 93:9085.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9085
-
-
Kato, K.1
Shimozato, O.2
Hoshi, K.3
Wakimoto, H.4
Hamada, H.5
Yagita, H.6
Okumura, K.7
-
19
-
-
0031255064
-
CTL generation in the presence of IL-4 is inhibited by free p40
-
Abdi, K., and S. H. Herrmann. 1997. CTL generation in the presence of IL-4 is inhibited by free p40. J. Immunol. 159:3148.
-
(1997)
J. Immunol.
, vol.159
, pp. 3148
-
-
Abdi, K.1
Herrmann, S.H.2
-
20
-
-
0031964713
-
Reduced T helper 1 responses in IL-12 p40 transgenic mice
-
Yoshimoto, T., C. Wang, T. Yoneto, S. Waki, S. Sunaga, Y. Komagata, M. Mitsuyama, J. Miyazaki, and H. Nariuchi. 1998. Reduced T helper 1 responses in IL-12 p40 transgenic mice. J. Immunol. 160:588.
-
(1998)
J. Immunol.
, vol.160
, pp. 588
-
-
Yoshimoto, T.1
Wang, C.2
Yoneto, T.3
Waki, S.4
Sunaga, S.5
Komagata, Y.6
Mitsuyama, M.7
Miyazaki, J.8
Nariuchi, H.9
-
21
-
-
0030240073
-
IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection
-
Piccotti, J. R., S. Y. Chan, R. E. Goodman, J. Magram, E. J. Eichwald, and D. K. Bishop. 1996. IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection. J. Immunol. 157:1951.
-
(1996)
J. Immunol.
, vol.157
, pp. 1951
-
-
Piccotti, J.R.1
Chan, S.Y.2
Goodman, R.E.3
Magram, J.4
Eichwald, E.J.5
Bishop, D.K.6
-
22
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen, M., and H. Bujard. 1995. Transcriptional activation by tetracyclines in mammalian cells. Science 268:1766.
-
(1995)
Science
, vol.268
, pp. 1766
-
-
Gossen, M.1
Bujard, H.2
-
23
-
-
0029763587
-
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
-
Kistner, A., M. Gossen, F. Zimmermann, J. Jerecic, C. Ullmer, H. Lubbert, and H. Bujard. 1996. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc. Natl. Acad. Sci. USA 93:10933.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10933
-
-
Kistner, A.1
Gossen, M.2
Zimmermann, F.3
Jerecic, J.4
Ullmer, C.5
Lubbert, H.6
Bujard, H.7
-
24
-
-
0031040987
-
Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts
-
Bohl, D., N. Naffakh, and J. M. Heard. 1997. Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts. Nat. Med. 3:299.
-
(1997)
Nat. Med.
, vol.3
, pp. 299
-
-
Bohl, D.1
Naffakh, N.2
Heard, J.M.3
-
25
-
-
0031253635
-
IL-12 induces TFN-γ expression and secretion in mouse peritoneal macrophages
-
Puddu, P., L. Fantuzzi, P. Borghi, B. Varano, G. Rainaldi, E. Guillemard, W. Malorni, P. Nicaise, S. F. Wolf, F. Belardelli, and S. Gessani. 1997. IL-12 induces TFN-γ expression and secretion in mouse peritoneal macrophages. J. Immunol. 159:3490.
-
(1997)
J. Immunol.
, vol.159
, pp. 3490
-
-
Puddu, P.1
Fantuzzi, L.2
Borghi, P.3
Varano, B.4
Rainaldi, G.5
Guillemard, E.6
Malorni, W.7
Nicaise, P.8
Wolf, S.F.9
Belardelli, F.10
Gessani, S.11
-
26
-
-
0023686225
-
Contrasting in vitro lymphocyte chemotactic activity of the hydroxyl enantiomers of 12-hydroxy-5,8,10,14-eicosatetraenoic acid
-
Bacon, K., R. D. Camp, F. M. Cunningham, and P. M. Woollard. 1988. Contrasting in vitro lymphocyte chemotactic activity of the hydroxyl enantiomers of 12-hydroxy-5,8,10,14-eicosatetraenoic acid. Br. J. Pharmacol. 95:966.
-
(1988)
Br. J. Pharmacol.
, vol.95
, pp. 966
-
-
Bacon, K.1
Camp, R.D.2
Cunningham, F.M.3
Woollard, P.M.4
-
28
-
-
0031711866
-
Rapid recruitment of macrophages in IL-12-mediated tumor regression
-
Ha, S. J., S. B. Lee, C. M. Kim, H. S. Shin, and Y. C. Sung. 1998. Rapid recruitment of macrophages in IL-12-mediated tumor regression. Immunology 95:156.
-
(1998)
Immunology
, vol.95
, pp. 156
-
-
Ha, S.J.1
Lee, S.B.2
Kim, C.M.3
Shin, H.S.4
Sung, Y.C.5
-
29
-
-
0027960722
-
Inhibition of in vivo tumor growth by the β chemokine, TCA3
-
Laning, J., H. Kawasaki, E. Tanaka, Y. Luo, and M. E. Dorf. 1994. Inhibition of in vivo tumor growth by the β chemokine, TCA3. J. Immunol. 153:4625.
-
(1994)
J. Immunol.
, vol.153
, pp. 4625
-
-
Laning, J.1
Kawasaki, H.2
Tanaka, E.3
Luo, Y.4
Dorf, M.E.5
-
30
-
-
0024502120
-
Murine interleukin-4 displays potent anti-tumor activity in vivo
-
Tepper, R. I., P. K. Pattengale, and P. Leder. 1989. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 57:503.
-
(1989)
Cell
, vol.57
, pp. 503
-
-
Tepper, R.I.1
Pattengale, P.K.2
Leder, P.3
-
31
-
-
0026657391
-
An eosinophil-dependent mechanism for the antitumor effect of interleukin-4
-
Tepper, R. I., R. L. Coffman, and P. Leder. 1992. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 257:548.
-
(1992)
Science
, vol.257
, pp. 548
-
-
Tepper, R.I.1
Coffman, R.L.2
Leder, P.3
-
32
-
-
0026500980
-
Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma
-
Bottazzi, B., S. Walter, D. Govoni, F. Colotta, and A. Mantovani. 1992. Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma. J. Immunol. 148:1280.
-
(1992)
J. Immunol.
, vol.148
, pp. 1280
-
-
Bottazzi, B.1
Walter, S.2
Govoni, D.3
Colotta, F.4
Mantovani, A.5
-
33
-
-
0032528446
-
The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor
-
Tannenbaum, C. S., R. Tubbs, D. Armstrong, J. H. Finke, R. M. Bukowski, and T. A. Hamilton. 1998. The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor. J. Immunol. 161:927.
-
(1998)
J. Immunol.
, vol.161
, pp. 927
-
-
Tannenbaum, C.S.1
Tubbs, R.2
Armstrong, D.3
Finke, J.H.4
Bukowski, R.M.5
Hamilton, T.A.6
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