-
1
-
-
0034816964
-
Delineating the genetic basis of systemic lupus erythematosus
-
Wakeland EK, Liu K, Graham RR, Behrens TW. Delineating the genetic basis of systemic lupus erythematosus. Immunity 2001;15:397-408.
-
(2001)
Immunity
, vol.15
, pp. 397-408
-
-
Wakeland, E.K.1
Liu, K.2
Graham, R.R.3
Behrens, T.W.4
-
4
-
-
4344633188
-
Update on human systemic lupus erythematosus genetics
-
Tsao BP. Update on human systemic lupus erythematosus genetics. Curr Opin Rheumatol 2004;16:513-21.
-
(2004)
Curr Opin Rheumatol
, vol.16
, pp. 513-521
-
-
Tsao, B.P.1
-
5
-
-
0028445340
-
Polygenic control of susceptibility to murine systemic lupus erythematosus
-
Morel L, Rudofsky UH, Longmate JA, Schiffenbauer J, Wakeland EK. Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity 1994;1:219-29.
-
(1994)
Immunity
, vol.1
, pp. 219-229
-
-
Morel, L.1
Rudofsky, U.H.2
Longmate, J.A.3
Schiffenbauer, J.4
Wakeland, E.K.5
-
6
-
-
10344252778
-
Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus
-
Wandstrat AE, Nguyen C, Limaye N, Chan AY, Subramanian S, Tian XH, et al. Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus. Immunity 2004;21:769-80.
-
(2004)
Immunity
, vol.21
, pp. 769-780
-
-
Wandstrat, A.E.1
Nguyen, C.2
Limaye, N.3
Chan, A.Y.4
Subramanian, S.5
Tian, X.H.6
-
7
-
-
0035852650
-
The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
-
Morel L, Blenman KR, Croker BP, Wakeland EK. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc Natl Acad Sci U S A 2001;98:1787-92.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1787-1792
-
-
Morel, L.1
Blenman, K.R.2
Croker, B.P.3
Wakeland, E.K.4
-
8
-
-
0033059667
-
Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
-
Bickerstaff MC, Botto M, Hutchinson WL, Herbert J, Tennent GA, Bybee A, et al. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat Med 1999;5:694-7.
-
(1999)
Nat Med
, vol.5
, pp. 694-697
-
-
Bickerstaff, M.C.1
Botto, M.2
Hutchinson, W.L.3
Herbert, J.4
Tennent, G.A.5
Bybee, A.6
-
9
-
-
0033695963
-
Spontaneous autoimmune disease in FcγRIIB-deficient mice results from strain-specific epistasis
-
Bolland S, Ravetch JV. Spontaneous autoimmune disease in FcγRIIB-deficient mice results from strain-specific epistasis. Immunity 2000;13:277-85.
-
(2000)
Immunity
, vol.13
, pp. 277-285
-
-
Bolland, S.1
Ravetch, J.V.2
-
10
-
-
0036735306
-
Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice
-
Miwa T, Maldonado MA, Zhou L, Sun X, Luo HY, Cai D, et al. Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice. Am J Pathol 2002;161:1077-86.
-
(2002)
Am J Pathol
, vol.161
, pp. 1077-1086
-
-
Miwa, T.1
Maldonado, M.A.2
Zhou, L.3
Sun, X.4
Luo, H.Y.5
Cai, D.6
-
11
-
-
0036888554
-
New regulatory co-receptors: Inducible co-stimulator and PD-1
-
Okazaki T, Iwai Y, Honjo T. New regulatory co-receptors: inducible co-stimulator and PD-1. Curr Opin Immunol 2002;14:779-82.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 779-782
-
-
Okazaki, T.1
Iwai, Y.2
Honjo, T.3
-
12
-
-
0038272058
-
A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen
-
Xue D, Shi H, Smith JD, Chen X, Noe DA, Cedervall T, et al. A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen. Proc Natl Acad Sci U S A 2003;100:7503-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7503-7508
-
-
Xue, D.1
Shi, H.2
Smith, J.D.3
Chen, X.4
Noe, D.A.5
Cedervall, T.6
-
13
-
-
0035879213
-
Chromatin-independent binding of serum amyloid P component to apoptotic cells
-
Familian A, Zwart B, Huisman HG, Rensink I, Roem D, Hordijk PL, et al. Chromatin-independent binding of serum amyloid P component to apoptotic cells. J Immunol 2001;167:647-54.
-
(2001)
J Immunol
, vol.167
, pp. 647-654
-
-
Familian, A.1
Zwart, B.2
Huisman, H.G.3
Rensink, I.4
Roem, D.5
Hordijk, P.L.6
-
14
-
-
19344369383
-
Spontaneous autoimmunity in 129 and C57BL/6 mice - implications for autoimmunity described in gene-targeted mice
-
Bygrave AE, Rose KL, Cortes-Hernandez J, Warren J, Rigby RJ, Cook HT, et al. Spontaneous autoimmunity in 129 and C57BL/6 mice - implications for autoimmunity described in gene-targeted mice. PLoS Biol 2004;2:E243.
-
(2004)
PLoS Biol
, vol.2
-
-
Bygrave, A.E.1
Rose, K.L.2
Cortes-Hernandez, J.3
Warren, J.4
Rigby, R.J.5
Cook, H.T.6
-
15
-
-
0018707316
-
1 mice: Elation to naturally occurring antibodies against murine leukemia virus-related cell surface antigens
-
1 mice: elation to naturally occurring antibodies against murine leukemia virus-related cell surface antigens. Proc Natl Acad Sci U S A 1979;76:5289-93.
-
(1979)
Proc Natl Acad Sci U S A
, vol.76
, pp. 5289-5293
-
-
Obata, Y.1
Tanaka, T.2
Stocken, E.3
Good, R.A.4
-
16
-
-
0031778836
-
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
-
Botto M, Dell'Agnola C, Bygrave AE, Thompson EM, Cook HT, Petry F, et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998;19:56-9.
-
(1998)
Nat Genet
, vol.19
, pp. 56-59
-
-
Botto, M.1
Dell'Agnola, C.2
Bygrave, A.E.3
Thompson, E.M.4
Cook, H.T.5
Petry, F.6
-
17
-
-
0035478717
-
Role of cyclin kinase inhibitor p21 in systemic autoimmunity
-
Santiago-Raber ML, Lawson BR, Dummer W, Barnhouse M, Koundouris S, Wilson CB, et al. Role of cyclin kinase inhibitor p21 in systemic autoimmunity. J Immunol 2001;167:4067-74.
-
(2001)
J Immunol
, vol.167
, pp. 4067-4074
-
-
Santiago-Raber, M.L.1
Lawson, B.R.2
Dummer, W.3
Barnhouse, M.4
Koundouris, S.5
Wilson, C.B.6
-
18
-
-
33750308551
-
Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus
-
Heidari Y, Bygrave AE, Rigby RJ, Rose KL, Walport MJ, Cook HT, et al. Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus. Genes Immun 2006;7:592-9.
-
(2006)
Genes Immun
, vol.7
, pp. 592-599
-
-
Heidari, Y.1
Bygrave, A.E.2
Rigby, R.J.3
Rose, K.L.4
Walport, M.J.5
Cook, H.T.6
-
19
-
-
33846906478
-
Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 loci when expressed on C57BL/6 mice
-
Carlucci F, Cortes-Hernandez J, Fossati-Jimack L, Bygrave AE, Walport MJ, Vyse TJ, et al. Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 loci when expressed on C57BL/6 mice. J Immunol 2007;178:2352-60.
-
(2007)
J Immunol
, vol.178
, pp. 2352-2360
-
-
Carlucci, F.1
Cortes-Hernandez, J.2
Fossati-Jimack, L.3
Bygrave, A.E.4
Walport, M.J.5
Vyse, T.J.6
-
20
-
-
32844455926
-
B-cell tolerance
-
Ferry H, Leung JC, Lewis G, Nijnik A, Silver K, Lambe T, et al. B-cell tolerance. Transplantation 2006;81:308-15.
-
(2006)
Transplantation
, vol.81
, pp. 308-315
-
-
Ferry, H.1
Leung, J.C.2
Lewis, G.3
Nijnik, A.4
Silver, K.5
Lambe, T.6
-
22
-
-
0025948793
-
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
-
Hartley SB, Crosbie J, Brink R, Kantor AB, Basten A, Goodnow CC. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 1991;353:765-9.
-
(1991)
Nature
, vol.353
, pp. 765-769
-
-
Hartley, S.B.1
Crosbie, J.2
Brink, R.3
Kantor, A.B.4
Basten, A.5
Goodnow, C.C.6
-
23
-
-
0023729241
-
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
-
Goodnow CC, Crosbie J, Adelstein S, Lavoie TB, Smith-Gill SJ, Brink RA, et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 1988;334:676-82.
-
(1988)
Nature
, vol.334
, pp. 676-682
-
-
Goodnow, C.C.1
Crosbie, J.2
Adelstein, S.3
Lavoie, T.B.4
Smith-Gill, S.J.5
Brink, R.A.6
-
24
-
-
0025817420
-
Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen
-
Adelstein S, Pritchard-Briscoe H, Anderson TA, Crosbie J, Gammon G, Loblay RH, et al. Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. Science 1991;251:1223-5.
-
(1991)
Science
, vol.251
, pp. 1223-1225
-
-
Adelstein, S.1
Pritchard-Briscoe, H.2
Anderson, T.A.3
Crosbie, J.4
Gammon, G.5
Loblay, R.H.6
-
25
-
-
0029553058
-
Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
-
Chen C, Nagy Z, Prak EL, Weigert M. Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. Immunity 1995;3:747-55.
-
(1995)
Immunity
, vol.3
, pp. 747-755
-
-
Chen, C.1
Nagy, Z.2
Prak, E.L.3
Weigert, M.4
-
26
-
-
0026029759
-
Ig H and L chain contributions to autoimmune specificities
-
Radic MZ, Mascelli MA, Erikson J, Shan H, Weigert M. Ig H and L chain contributions to autoimmune specificities. J Immunol 1991;146:176-82.
-
(1991)
J Immunol
, vol.146
, pp. 176-182
-
-
Radic, M.Z.1
Mascelli, M.A.2
Erikson, J.3
Shan, H.4
Weigert, M.5
-
27
-
-
0029164869
-
Light chain replacement: A new model for antibody gene rearrangement
-
Prak EL, Weigert M. Light chain replacement: a new model for antibody gene rearrangement. J Exp Med 1995;182:541-8.
-
(1995)
J Exp Med
, vol.182
, pp. 541-548
-
-
Prak, E.L.1
Weigert, M.2
-
28
-
-
0030997499
-
Editing disease-associated autoantibodies
-
Chen C, Prak EL, Weigert M. Editing disease-associated autoantibodies. Immunity 1997;6:97-105.
-
(1997)
Immunity
, vol.6
, pp. 97-105
-
-
Chen, C.1
Prak, E.L.2
Weigert, M.3
-
29
-
-
0025980973
-
Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
-
Erikson J, Radic MZ, Camper SA, Hardy RR, Carmack C, Weigert M. Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature 1991;349:331-4.
-
(1991)
Nature
, vol.349
, pp. 331-334
-
-
Erikson, J.1
Radic, M.Z.2
Camper, S.A.3
Hardy, R.R.4
Carmack, C.5
Weigert, M.6
-
30
-
-
0037090275
-
Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells
-
Sekiguchi DR, Jainandunsing SM, Fields ML, Maldonado MA, Madaio MP, Erikson J, et al. Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells. J Immunol 2002;168:4142-53.
-
(2002)
J Immunol
, vol.168
, pp. 4142-4153
-
-
Sekiguchi, D.R.1
Jainandunsing, S.M.2
Fields, M.L.3
Maldonado, M.A.4
Madaio, M.P.5
Erikson, J.6
-
32
-
-
0032822989
-
Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice
-
Brard F, Shannon M, Prak EL, Litwin S, Weigert M. Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice. J Exp Med 1999;190:691-704.
-
(1999)
J Exp Med
, vol.190
, pp. 691-704
-
-
Brard, F.1
Shannon, M.2
Prak, E.L.3
Litwin, S.4
Weigert, M.5
-
33
-
-
0030757182
-
Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene
-
Botto M, Hawkins PN, Bickerstaff MC, Herbert J, Bygrave AE, McBride A, et al. Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene. Nat Med 1997;3:855-9.
-
(1997)
Nat Med
, vol.3
, pp. 855-859
-
-
Botto, M.1
Hawkins, P.N.2
Bickerstaff, M.C.3
Herbert, J.4
Bygrave, A.E.5
McBride, A.6
-
34
-
-
0026001262
-
Influence of a Vκ 8 L chain transgene on endogenous rearrangements and the immune response to the HA(Sb) determinant on influenza virus
-
Carmack CE, Camper SA, Mackle JJ, Gerhard WU, Weigert MG. Influence of a Vκ 8 L chain transgene on endogenous rearrangements and the immune response to the HA(Sb) determinant on influenza virus. J Immunol 1991;147:2024-33.
-
(1991)
J Immunol
, vol.147
, pp. 2024-2033
-
-
Carmack, C.E.1
Camper, S.A.2
Mackle, J.J.3
Gerhard, W.U.4
Weigert, M.G.5
-
35
-
-
0027499537
-
Receptor editing: An approach by autoreactive B cells to escape tolerance
-
Gay D, Saunders T, Camper S, Weigert M. Receptor editing: an approach by autoreactive B cells to escape tolerance. J Exp Med 1993;177:999-1008.
-
(1993)
J Exp Med
, vol.177
, pp. 999-1008
-
-
Gay, D.1
Saunders, T.2
Camper, S.3
Weigert, M.4
-
36
-
-
34848855068
-
C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice
-
Fossati-Jimack L, Cortes-Hernandez J, Norsworthy PJ, Walport MJ, Cook HT, Botto M. C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice. Mol Immunol 2008;45:787-95.
-
(2008)
Mol Immunol
, vol.45
, pp. 787-795
-
-
Fossati-Jimack, L.1
Cortes-Hernandez, J.2
Norsworthy, P.J.3
Walport, M.J.4
Cook, H.T.5
Botto, M.6
-
37
-
-
0035338308
-
Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice
-
Robson MG, Cook HT, Botto M, Taylor PR, Busso N, Salvi R, et al. Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice. J Immunol 2001;166:6820-8.
-
(2001)
J Immunol
, vol.166
, pp. 6820-6828
-
-
Robson, M.G.1
Cook, H.T.2
Botto, M.3
Taylor, P.R.4
Busso, N.5
Salvi, R.6
-
38
-
-
0037148509
-
Autoreactive B cells in the marginal zone that express dual receptors
-
Li Y, Li H, Weigert M. Autoreactive B cells in the marginal zone that express dual receptors. J Exp Med 2002;195:181-8.
-
(2002)
J Exp Med
, vol.195
, pp. 181-188
-
-
Li, Y.1
Li, H.2
Weigert, M.3
-
39
-
-
0037144519
-
Evolution of autoantibody responses via somatic hypermutation outside of germinal centers
-
William J, Euler C, Christensen S, Shlomchik MJ. Evolution of autoantibody responses via somatic hypermutation outside of germinal centers. Science 2002;297:2066-70.
-
(2002)
Science
, vol.297
, pp. 2066-2070
-
-
William, J.1
Euler, C.2
Christensen, S.3
Shlomchik, M.J.4
-
40
-
-
18344369175
-
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells
-
Seo SJ, Fields ML, Buckler JL, Reed AJ, Mandik-Nayak L, Nish SA, et al. The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity 2002;16:535-46.
-
(2002)
Immunity
, vol.16
, pp. 535-546
-
-
Seo, S.J.1
Fields, M.L.2
Buckler, J.L.3
Reed, A.J.4
Mandik-Nayak, L.5
Nish, S.A.6
-
42
-
-
33745161013
-
Regulation of B cell tolerance by the lupus susceptibility gene Ly108
-
Kumar KR, Li L, Yan M, Bhaskarabhatla M, Mobley AB, Nguyen C, et al. Regulation of B cell tolerance by the lupus susceptibility gene Ly108. Science 2006;312:1665-9.
-
(2006)
Science
, vol.312
, pp. 1665-1669
-
-
Kumar, K.R.1
Li, L.2
Yan, M.3
Bhaskarabhatla, M.4
Mobley, A.B.5
Nguyen, C.6
-
43
-
-
0031053838
-
Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone
-
Chen X, Martin F, Forbush KA, Perlmutter RM, Kearney JF. Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone. Int Immunol 1997;9:27-41.
-
(1997)
Int Immunol
, vol.9
, pp. 27-41
-
-
Chen, X.1
Martin, F.2
Forbush, K.A.3
Perlmutter, R.M.4
Kearney, J.F.5
-
44
-
-
33746903496
-
Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help
-
Mandik-Nayak L, Racz J, Sleckman BP, Allen PM. Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help. J Exp Med 2006;203:1985-98.
-
(2006)
J Exp Med
, vol.203
, pp. 1985-1998
-
-
Mandik-Nayak, L.1
Racz, J.2
Sleckman, B.P.3
Allen, P.M.4
-
45
-
-
0346734179
-
Impaired clearance of apoptotic cells induces the activation of autoreactive anti-Sm marginal zone and B-1 B cells
-
Qian Y, Wang H, Clarke SH. Impaired clearance of apoptotic cells induces the activation of autoreactive anti-Sm marginal zone and B-1 B cells. J Immunol 2004;172:625-35.
-
(2004)
J Immunol
, vol.172
, pp. 625-635
-
-
Qian, Y.1
Wang, H.2
Clarke, S.H.3
-
46
-
-
15244363080
-
Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses
-
Lim HW, Hillsamer P, Kim CH. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J Clin Invest 2004;114:1640-9.
-
(2004)
J Clin Invest
, vol.114
, pp. 1640-1649
-
-
Lim, H.W.1
Hillsamer, P.2
Kim, C.H.3
-
47
-
-
17244378876
-
MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus
-
Monk CR, Spachidou M, Rovis F, Leung E, Botto M, Lechler RI, et al. MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus. Arthritis Rheum 2005;52:1180-4.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1180-1184
-
-
Monk, C.R.1
Spachidou, M.2
Rovis, F.3
Leung, E.4
Botto, M.5
Lechler, R.I.6
-
48
-
-
0031893204
-
Genetic susceptibility to systemic lupus erythematosus
-
Vyse TJ, Kotzin BL. Genetic susceptibility to systemic lupus erythematosus. Annu Rev Immunol 1998;16:261-92.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 261-292
-
-
Vyse, T.J.1
Kotzin, B.L.2
-
49
-
-
26944456633
-
Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus
-
Blank MC, Stefanescu RN, Masuda E, Marti F, King PD, Redecha PB, et al. Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus. Hum Genet 2005;117:220-7.
-
(2005)
Hum Genet
, vol.117
, pp. 220-227
-
-
Blank, M.C.1
Stefanescu, R.N.2
Masuda, E.3
Marti, F.4
King, P.D.5
Redecha, P.B.6
|