A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 13, 2003, Pages 7503-7508

  Xue, Dahai ^a   Shi, Hong ^a   Smith, James D ^a   Chen, Xinguo ^a   Noe, Dennis A ^a   Cedervall, Tommy ^a   Yangt, Derek D ^a   Eynon, Elizabeth ^a   Brash, Douglas E ^a   Kashgarian, Michael ^a   Flavell, Richard A ^a   Wolin, Sandra L ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; AUTOANTIGEN RO; CHROMATIN ANTIBODY; DNA; RIBONUCLEOPROTEIN; RIBOSOME ANTIBODY; RNA 5S; RNA BINDING PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CONGENITAL HEART BLOCK; CONTROLLED STUDY; DEINOCOCCUS RADIODURANS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOSURVEILLANCE; MALE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; MOUSE; NONHUMAN; PHOTOSENSITIVITY DISORDER; PRIORITY JOURNAL; QUALITY CONTROL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; ULTRAVIOLET IRRADIATION;

ANIMALS; AUTOANTIGENS; B-LYMPHOCYTES; CROSSES, GENETIC; DOSE-RESPONSE RELATIONSHIP, RADIATION; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; HETEROZYGOTE; KIDNEY; LUPUS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, GENETIC; RIBONUCLEOPROTEINS; RIBOSOMES; RNA; RNA, SMALL CYTOPLASMIC; SUBCELLULAR FRACTIONS; SYNDROME; T-LYMPHOCYTES; ULTRAVIOLET RAYS;

ANIMALIA; BACTERIA (MICROORGANISMS); DEINOCOCCUS; DEINOCOCCUS RADIODURANS; EUKARYOTA;

EID: 0038272058     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0832411100     Document Type: Article

References (49)

1. von Muhlen, C. A. & Tan, E. M. (1995) Semin. Arthritis Rheum 24, 323-358.
2. Provost, T. T., Watson, R. & Simmons-O'Brien, E. (1996) J. Am. Acad. Dermatol. 35, 147-169.
3. Silverman, E. D. & Laxer, R. M. (1997) Rheum. Dis. Clin. North Am. 23, 599-618.
4. Peek, R., Pruijn, G. J. M., van der Kemp, A. & van Venrooij, W. J. (1993) J. Cell Sci, 106, 929-935.
5. Simons, F. H. M., Pruijn, G. J. M. & van Venrooij, W. J. (1994) J. Cell Biol, 125, 981-988.
6. O'Brien, C. A. & Wolin, S. L. (1994) Genes Dev. 8, 2891-2903.
7. Wolin, S. L. & Steitz, J. A. (1983) Cell 32, 735-744.
8. Wolin, S, L. & Steitz, J. A. (1984) Proc. Natl. Acad. Sci. USA 81, 1996-2000.
9. O'Brien, C. A., Margelot, K. & Wolin, S. L. (1993) Proc. Natl. Acad. Sci. USA 90, 7250-7254.
10. Farris, A. D., O'Brien, C. A, & Harley, J. B. (1995) Gene 154, 193-198.
11. Van Horn, D. J., Eisenberg, D., O'Brien, C. A. & Wolin S. L. (1995) RNA 1, 293-303.
12. Chen, X., Quinn, A. M. & Wolin, S. L. (2000) Genes Dev. 14, 777-782.
13. Labbe, J. C. Hekimi, S, & Rokeach, L. A. (1999) Genetics 151, 143-150.
14. Peterson, R. C., Doering, J. L. & Brown, D. D. (1980) Cell 20, 131-141.
15. Shi, H., O'Brien, C. A., Van Horn, D. J. & Wolin, S. L. (1996) RNA 2, 769-784.
16. Labbe, J. C., Burgess, J., Rokeach, L. A. & Hekimi, S. (2000) Proc. Natl. Acad. Sci. USA 97, 13233-13238.
17. Kaufman, K. M., Farris, A. D., Gross, J. K., Kirby, M. Y. & Harley, J. B, (2000) Genes Immunol. 1, 265-270.
18. Deutscher, S. L., Harley, J. B. & Keene, J. D. (1988) Proc. Natl. Acad. Sci. USA 85, 9479-9483.
19. Yang, D., Tournier, C., Wysk, M., Lu, H. T., Xu, J., Davis, R. J. & Flavell, R. A. (1997) Proc. Natl. Acad. Sci. USA 94, 3004-3009.
20. Liang, B., Gee, R. J., Kashgarian, M. J., Sharpe, A. H. & Mamula, M. J. (1999) J. Immunol. 163, 2322-2329.
21. Yoo, C. J. & Wolin, S. L. (1994) Mol. Cell. Biol. 14, 5412-5424.
22. Hardin, J. A., Rahn, D. R., Shen, C., Lerner, M. R., Wolin, S. L., Rosa, M. D. & Steitz, J. A. (1982) J. Clin. Invest. 70, 141-147.
23. England, T. E., Bruce, A. G. & Uhlenbeck. 0. C. (1980) Methods Enzymol. 65, 65-74.
24. Lerner, E. A., Lerner, M. R., Janeway, C. A., & Steitz, J. A. (1981) Proc. Natl. Acad. Sci. USA 78, 2737-2741.
25. Ziegler, A., Jonason, A. S., Leffell, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., Remington, L., Jacks, T. & Brash, D. E. (1994) Nature 372, 773-776.
26. Hendrick, J. P., Wolin, S. L., Rinke, J., Lerner, M. R. & Steitz, J. A. (1981) Mol. Cell. Biol. 1, 1138-1149.
27. Farris, A. D., Gross, J. K., Hanas, J. S. & Harley, J. B. (1996) Gene 174, 35-42.
28. Wakeland, E. K., Liu, K., Graham, R. R. & Behrens, T. W. (2001) Immunity 15, 397-408.
29. Andrews, A. D., Barrett, S. F. & Robbins, J. H. (1978) Proc. Natl Acad. Sci. USA 75, 1984-1988.
30. Bootsma, D., Kraemer, K. H., Cleaver, J. E. & Hoeijmakers, J. H. J. (2001) in The Metabolic and Molecular Base of Inherited Disease, eds. Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D. (MeGraw -Hill, New York), Vol. 1, pp. 677-703.
31. Lanzavecchi, A. (1995) J. Exp. Med. 181, 1945-1948.
32. Andrade, F., Casciola-Rosen, L. & Rosen, A. (2000) Rheum. Dis. Clin. North Am. 26, 215-227.
33. Botto, M., Dell'Agnola, C., Bygrave A. E., Thompson, E. M., Cook, H. T., Petry, F. Loos, M., Pandolfi, P. P. & Walport, M. J. (1998) Nat. Genet. 19, 56-59.
34. Bickerstaff, M. C., Botto, M., Hutchinson, W. L., Herbert, J., Tennent, G. A., Bybee,A., Mitchell, D. A., Cook, H. T., Butler, P. J., Walport, M. J., et al. (1999) Nat. Med. 5, 694-697.
35. Napirei, M., Karsunky, H., Zevnik, B., Stephan, H., Mannherz, H. G. & Moroy, T. (2000) Nat. Genet. 25, 177-181.
36. Scott, R. S., McMahon, E. J., Pop, S. M., Reap, E. A., Caricchio, R., Cohen, P. L., Earp, H. S. & Matsushima, G. K. (2001) Nature 411, 207-211.
37. Lee, L. A. (2001) Curr. Rheumatol. Rep. 3, 391-395.
38. Patel, P. & Werth, V. (2002) Dermatol. Clin. 20, 373-385.
39. Alarcon-Segovia, D., Ruiz-Arguelles, A. & Fishbein, E. (1978) Nature 271, 67-69.
40. Ma, J., Chapman, G. V., Chen, S. L., Melick, G., Penny, R. & Breit, S. N. (1991) Clin. Exp. Immunol. 84, 83-91.
41. Yanase, K, Smith, R. M., Cizman, B., Foster, M. H., Peachey, L. D., Jarett, L. & Madaio, M. P. (1994) Lab. Invest. 71, 52-60.
42. Zack, D. J., Stempniak, Sternpniak, M., Wong A. L., Taylor, C. & Weisbart, R. H. (1996) J. Immunol. 157, 2082-2088.
43. Koscec, M., Koren, E., Wolfson-Reichlin, M., Fugate, R. D., Trieu, E., Targoff, I. N. & Reichlin, M. (1997) J. Immunol 159, 2033-2041.
44. Deng, S. X., Hanson, E. & Sanz I. (2000) Int. Immunol. 12, 415-423.
45. Musunuru, K. & R. Darnell, R. B. (2001) Annu. Rev. Neurosci. 24, 239-262.
46. Chan, E. K., Tan, E. M., Ward, D. C. & Matera, A. G. (1994) Genomics 23, 298-300.
47. Moser, K. L., Neas, B. R., Salmon, J. E., Yu, H., Gray-McGuire C., Asundi, N., Bruner, G. R., Fox, J., Kelly, J., Henshall S., et al. (1998) Proc. Natl. Acad. Sci. USA 95, 14869-14874.
48. Lindqvist, A. K., Steinsson, K., Johanneson, B., Kristjansdottir, H., Arnasson, A., Grondal, G., Jonasson I., Magnusson, V., Sturfelt, G., Truedsson, L., et al. (2000) J. Autoimmun. 14, 169-178.
49. Johanneson, B., Lima, G., Von Salome, J., Alarcon-Segovia, D. & Alarcon-Riquelme, M. E. (2002) Am. J. Hum. Genet. 71, 1060-1071.