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Volumn 1129, Issue , 2008, Pages 236-245

Neuronal mechanisms underlying attention deficit hyperactivity disorder: The influence of arousal on prefrontal cortical function

Author keywords

Attention; Cognition; Dopamine; Norepinephrine; Prefrontal cortex; Stress

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; AMPHETAMINE; ATOMOXETINE; BETA 1 ADRENERGIC RECEPTOR; CATECHOLAMINE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; GUANFACINE; METHYLPHENIDATE; NEUROTRANSMITTER; NORADRENALIN;

EID: 47249118841     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1417.007     Document Type: Conference Paper
Times cited : (209)

References (105)
  • 1
    • 0034952122 scopus 로고    scopus 로고
    • Brain imaging of attention deficit/hyperactivity disorder
    • Giedd, J.N. et al. 2001. Brain imaging of attention deficit/hyperactivity disorder. Ann. N. Y. Acad. Sci. 931 : 33 49.
    • (2001) Ann. N. Y. Acad. Sci. , vol.931 , pp. 33-49
    • Giedd, J.N.1
  • 2
    • 20444424892 scopus 로고    scopus 로고
    • The cognitive neuroscience of response inhibition: Relevance for genetic research in attention-deficit/hyperactivity disorder
    • &
    • Aron, A.R. & R.A. Poldrack. 2005. The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/ hyperactivity disorder. Biol. Psychiatry 57 : 1285 1292.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1285-1292
    • Aron, A.R.1    Poldrack, R.A.2
  • 3
    • 0000292303 scopus 로고
    • Circuitry of the primate prefrontal cortex and the regulation of behavior by representational memory
    • In. F. Plum, Ed. American Physiological Society. Bethesda, MD.
    • Goldman-Rakic, P.S. 1987. Circuitry of the primate prefrontal cortex and the regulation of behavior by representational memory. In Handbook of Physiology, The Nervous System, Higher Functions of the Brain, Vol. V. F. Plum, Ed 373 417. American Physiological Society. Bethesda, MD.
    • (1987) Handbook of Physiology, the Nervous System, Higher Functions of the Brain , vol.5 , pp. 373-417
    • Goldman-Rakic, P.S.1
  • 4
    • 23144442004 scopus 로고    scopus 로고
    • Relationship of prefrontal connections to inhibitory systems in superior temporal areas in the rhesus monkey
    • Barbas, H. et al. 2005. Relationship of prefrontal connections to inhibitory systems in superior temporal areas in the rhesus monkey. Cereb. Cortex. 15 : 1356 1370.
    • (2005) Cereb. Cortex. , vol.15 , pp. 1356-1370
    • Barbas, H.1
  • 5
    • 0034710886 scopus 로고    scopus 로고
    • Mechanisms and streams for processing of "what" and "where" in auditory cortex
    • &
    • Rauschecker, J.P. & B. Tian. 2000. Mechanisms and streams for processing of "what" and "where" in auditory cortex. Proc. Natl. Acad. Sci. USA 97 : 11800 11806.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11800-11806
    • Rauschecker, J.P.1    Tian, B.2
  • 6
    • 0030472773 scopus 로고    scopus 로고
    • Neural mechanisms for visual memory and their role in attention
    • Desimone, R. 1996. Neural mechanisms for visual memory and their role in attention. Proc. Natl. Acad. Sci. USA 93 : 13494 13499.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13494-13499
    • Desimone, R.1
  • 7
    • 0032475917 scopus 로고    scopus 로고
    • Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI
    • Kastner, S. et al. 1998. Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI. Science 282 : 108 111.
    • (1998) Science , vol.282 , pp. 108-111
    • Kastner, S.1
  • 8
    • 0032530364 scopus 로고    scopus 로고
    • Where and when to pay attention: The neural systems for directing attention to spatial locations and to time intervals as revealed by both PET and fMRI
    • &
    • Coull, J.T. & A.C. Nobre. 1998. Where and when to pay attention: the neural systems for directing attention to spatial locations and to time intervals as revealed by both PET and fMRI. J. Neurosci. 18 : 7426 7435.
    • (1998) J. Neurosci. , vol.18 , pp. 7426-7435
    • Coull, J.T.1    Nobre, A.C.2
  • 10
    • 0345731428 scopus 로고    scopus 로고
    • Neural activity in primate parietal area 7a related to spatial analysis of visual mazes
    • Crowe, D.A. et al. 2004. Neural activity in primate parietal area 7a related to spatial analysis of visual mazes. Cereb. Cortex 14 : 23 34.
    • (2004) Cereb. Cortex , vol.14 , pp. 23-34
    • Crowe, D.A.1
  • 11
    • 0032572753 scopus 로고    scopus 로고
    • Separate body- and world-referenced representations of visual space in parietal cortex
    • Snyder, L.H. et al. 1998. Separate body- and world-referenced representations of visual space in parietal cortex. Nature 394 : 887 891.
    • (1998) Nature , vol.394 , pp. 887-891
    • Snyder, L.H.1
  • 12
    • 0028938076 scopus 로고
    • Cellular basis of working memory
    • Goldman-Rakic, P.S. 1995. Cellular basis of working memory. Neuron 14 : 477 485.
    • (1995) Neuron , vol.14 , pp. 477-485
    • Goldman-Rakic, P.S.1
  • 13
    • 0027394621 scopus 로고
    • Activity of neurons in anterior inferior temporal cortex during a short-term memory task
    • &
    • Miller, E.K., L. Li & R. Desimone. 1993. Activity of neurons in anterior inferior temporal cortex during a short-term memory task. J. Neurosci. 13 : 1460 1478.
    • (1993) J. Neurosci. , vol.13 , pp. 1460-1478
    • Miller, E.K.1    Li, L.2    Desimone, R.3
  • 14
    • 0027507756 scopus 로고
    • Prefrontal neuronal activity in rhesus monkeys performing a delayed anti-saccade task
    • &
    • Funahashi, S., M.V. Chafee & P.S. Goldman-Rakic. 1993. Prefrontal neuronal activity in rhesus monkeys performing a delayed anti-saccade task. Nature 365 : 753 756.
    • (1993) Nature , vol.365 , pp. 753-756
    • Funahashi, S.1    Chafee, M.V.2    Goldman-Rakic, P.S.3
  • 15
    • 8944248282 scopus 로고    scopus 로고
    • Quantitative brain magnetic resonance imaging in attention deficit/hyperactivity disorder
    • Castellanos, F.X. et al. 1996. Quantitative brain magnetic resonance imaging in attention deficit/hyperactivity disorder. Arch. Gen. Psychiatry 53 : 607 616.
    • (1996) Arch. Gen. Psychiatry , vol.53 , pp. 607-616
    • Castellanos, F.X.1
  • 16
    • 0008193295 scopus 로고    scopus 로고
    • Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder
    • Casey, B.J. et al. 1997. Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder. J. Am. Acad. Child Adolesc. Psychiatry 36 : 374 383.
    • (1997) J. Am. Acad. Child Adolesc. Psychiatry , vol.36 , pp. 374-383
    • Casey, B.J.1
  • 17
    • 0345414665 scopus 로고    scopus 로고
    • Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder
    • Sowell, E.R. et al. 2003. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 362 : 1699 1707.
    • (2003) Lancet , vol.362 , pp. 1699-1707
    • Sowell, E.R.1
  • 18
    • 0037147663 scopus 로고    scopus 로고
    • Orbitofrontal cortex dysfunction in attention-deficit hyperactivity disorder revealed by reversal and extinction tasks
    • &
    • Itami, S. & H. Uno. 2002. Orbitofrontal cortex dysfunction in attention-deficit hyperactivity disorder revealed by reversal and extinction tasks. Neuroreport 13 : 2453 2457.
    • (2002) Neuroreport , vol.13 , pp. 2453-2457
    • Itami, S.1    Uno, H.2
  • 19
    • 0037798968 scopus 로고    scopus 로고
    • Selective inhibition in children with attention-deficit hyperactivity disorder off and on stimulant medication
    • Bedard, A.C. et al. 2003. Selective inhibition in children with attention-deficit hyperactivity disorder off and on stimulant medication. J. Abnorm. Child Psychol. 31 : 315 327.
    • (2003) J. Abnorm. Child Psychol. , vol.31 , pp. 315-327
    • Bedard, A.C.1
  • 20
    • 2342554486 scopus 로고    scopus 로고
    • Characteristic neurocognitive profile associated with adult attention-deficit/hyperactivity disorder
    • McLean, A. et al. 2004. Characteristic neurocognitive profile associated with adult attention-deficit/hyperactivity disorder. Psychol. Med. 34 : 681 692.
    • (2004) Psychol. Med. , vol.34 , pp. 681-692
    • McLean, A.1
  • 21
    • 1842524325 scopus 로고    scopus 로고
    • Inhibition and the right inferior frontal cortex
    • &
    • Aron, A.R., T.W. Robbins & R.A. Poldrack. 2004. Inhibition and the right inferior frontal cortex. Trends Cogn. Sci. 8 : 170 177.
    • (2004) Trends Cogn. Sci. , vol.8 , pp. 170-177
    • Aron, A.R.1    Robbins, T.W.2    Poldrack, R.A.3
  • 23
    • 0030110801 scopus 로고    scopus 로고
    • Divided and focused attention in patients with lesion of the prefrontal cortex
    • &
    • Godefroy, O. & M. Rousseaux. 1996. Divided and focused attention in patients with lesion of the prefrontal cortex. Brain Cogn. 30 : 155 174.
    • (1996) Brain Cogn. , vol.30 , pp. 155-174
    • Godefroy, O.1    Rousseaux, M.2
  • 24
    • 0017361575 scopus 로고
    • Frontal decortication in rhesus monkeys: A test of the interference hypothesis
    • &
    • Bartus, R.T. & T.E. Levere. 1977. Frontal decortication in rhesus monkeys: a test of the interference hypothesis. Brain Res. 119 : 233 248.
    • (1977) Brain Res. , vol.119 , pp. 233-248
    • Bartus, R.T.1    Levere, T.E.2
  • 25
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • &
    • Birrell, J.M. & V.J. Brown. 2000. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 20 : 4320 4324.
    • (2000) J. Neurosci. , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 26
    • 0031896813 scopus 로고    scopus 로고
    • Cerebellum in attention-deficit hyperactivity disorder: A morphometric MRI study
    • Berquin, P.C. et al. 1998. Cerebellum in attention-deficit hyperactivity disorder: a morphometric MRI study. Neurology 50 : 1087 1093.
    • (1998) Neurology , vol.50 , pp. 1087-1093
    • Berquin, P.C.1
  • 27
    • 20444414098 scopus 로고    scopus 로고
    • Structural brain imaging of attention-deficit/hyperactivity disorder
    • &
    • Seidman, L.J., E.M. Valera & N. Makris. 2005. Structural brain imaging of attention-deficit/hyperactivity disorder. Biol. Psychiatry 57 : 1263 1272.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1263-1272
    • Seidman, L.J.1    Valera, E.M.2    Makris, N.3
  • 28
    • 0037048693 scopus 로고    scopus 로고
    • Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder
    • Castellanos, F.X. et al. 2002. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. JAMA 288 : 1740 1748.
    • (2002) JAMA , vol.288 , pp. 1740-1748
    • Castellanos, F.X.1
  • 29
    • 0036964595 scopus 로고    scopus 로고
    • Motor and nonmotor domains in the monkey dentate
    • &
    • Dum, R.P., C. Li & P.L. Strick. 2002. Motor and nonmotor domains in the monkey dentate. Ann. N. Y. Acad. Sci. 978 : 289 301.
    • (2002) Ann. N. Y. Acad. Sci. , vol.978 , pp. 289-301
    • Dum, R.P.1    Li, C.2    Strick, P.L.3
  • 30
    • 27644450243 scopus 로고    scopus 로고
    • The cerebellum communicates with the basal ganglia
    • Hoshi, E. et al. 2005. The cerebellum communicates with the basal ganglia. Nat. Neurosci. 8 : 1491 1493.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1491-1493
    • Hoshi, E.1
  • 31
    • 0025854475 scopus 로고
    • Noradrenergic potentiation of excitatory transmitter action in cerebrocortical slices: Evidence of mediation by an alpha1-receptor-linked second messenger pathway
    • &
    • Mouradian, R.D., F.M. Seller & B.D. Waterhouse. 1991. Noradrenergic potentiation of excitatory transmitter action in cerebrocortical slices: evidence of mediation by an alpha1-receptor-linked second messenger pathway. Brain Res. 546 : 83 95.
    • (1991) Brain Res. , vol.546 , pp. 83-95
    • Mouradian, R.D.1    Seller, F.M.2    Waterhouse, B.D.3
  • 32
    • 0030825194 scopus 로고    scopus 로고
    • Alterations of brain noradrenergic activity in rhesus monkeys affects the alerting component of covert orienting
    • &
    • Witte, E.A. & R.T. Marrocco. 1997. Alterations of brain noradrenergic activity in rhesus monkeys affects the alerting component of covert orienting. Psychopharmacology 132 : 315 323.
    • (1997) Psychopharmacology , vol.132 , pp. 315-323
    • Witte, E.A.1    Marrocco, R.T.2
  • 33
    • 0034746694 scopus 로고    scopus 로고
    • The noradrenergic alpha2 agonist clonidine modulates behavioural and neuroanatomical correlates of human attentional orienting and alerting
    • &
    • Coull, J.T., A.C. Nobre & C.D. Frith. 2001. The noradrenergic alpha2 agonist clonidine modulates behavioural and neuroanatomical correlates of human attentional orienting and alerting. Cereb. Cortex 11 : 73 84.
    • (2001) Cereb. Cortex , vol.11 , pp. 73-84
    • Coull, J.T.1    Nobre, A.C.2    Frith, C.D.3
  • 34
    • 0018725135 scopus 로고
    • Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey
    • Brozoski, T. et al. 1979. Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 205 : 929 931.
    • (1979) Science , vol.205 , pp. 929-931
    • Brozoski, T.1
  • 35
    • 3142676620 scopus 로고    scopus 로고
    • Neurochemical modulation of prefrontal cortical function in humans and animals
    • & In. D.T. Stuss. & R.T. Knight, Eds. Oxford University Press. New York.
    • Arnsten, A.F.T. & T.W. Robbins. 2002. Neurochemical modulation of prefrontal cortical function in humans and animals. In Principles of Frontal Lobe Function. D.T. Stuss & R.T. Knight, Eds 51 84. Oxford University Press. New York.
    • (2002) Principles of Frontal Lobe Function. , pp. 51-84
    • Arnsten, A.F.T.1    Robbins, T.W.2
  • 36
    • 20444425251 scopus 로고    scopus 로고
    • Neurobiology of executive functions: Catecholamine influences on prefrontal cortical function
    • &
    • Arnsten, A.F.T. & B.-M. Li. 2005. Neurobiology of executive functions: catecholamine influences on prefrontal cortical function. Biol. Psychiatry 57 : 1377 1384.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1377-1384
    • Arnsten, A.F.T.1    Li, B.-M.2
  • 37
    • 77956782804 scopus 로고    scopus 로고
    • The phasic reward signal of primate dopamine neurons
    • Schultz, W. 1998. The phasic reward signal of primate dopamine neurons. Adv. Pharmacol. 42 : 686 690.
    • (1998) Adv. Pharmacol. , vol.42 , pp. 686-690
    • Schultz, W.1
  • 38
    • 0022379837 scopus 로고
    • Alpha-2 adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates
    • &
    • Arnsten, A.F.T. & P.S. Goldman-Rakic. 1985. Alpha-2 adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates. Science 230 : 1273 1276.
    • (1985) Science , vol.230 , pp. 1273-1276
    • Arnsten, A.F.T.1    Goldman-Rakic, P.S.2
  • 39
    • 0027318724 scopus 로고
    • Reserpine impairs spatial working memory performance in monkeys: Reversal by the alpha-2 adrenergic agonist clonidine
    • Cai, J.X. et al. 1993. Reserpine impairs spatial working memory performance in monkeys: reversal by the alpha-2 adrenergic agonist clonidine. Brain Res. 614 : 191 196.
    • (1993) Brain Res. , vol.614 , pp. 191-196
    • Cai, J.X.1
  • 40
    • 0036771838 scopus 로고    scopus 로고
    • Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine
    • Franowicz, J.S. et al. 2002. Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. J. Neurosci. 22 : 8771 8777.
    • (2002) J. Neurosci. , vol.22 , pp. 8771-8777
    • Franowicz, J.S.1
  • 41
    • 2642662683 scopus 로고    scopus 로고
    • The alpha-2A noradrenergic agonist, guanfacine, reverses the working memory deficits induced by pharmacological stress (FG7142)
    • &
    • Birnbaum, S.G. & A.F.T. Arnsten. 1996. The alpha-2A noradrenergic agonist, guanfacine, reverses the working memory deficits induced by pharmacological stress (FG7142). Soc. Neurosci. Abstr. 22 : 1126.
    • (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 1126
    • Birnbaum, S.G.1    Arnsten, A.F.T.2
  • 42
    • 0026705018 scopus 로고
    • Alpha-2 adrenergic agonists decrease distractability in aged monkeys performing a delayed response task
    • &
    • Arnsten, A.F.T. & T.A. Contant. 1992. Alpha-2 adrenergic agonists decrease distractability in aged monkeys performing a delayed response task. Psychopharmacology 108 : 159 169.
    • (1992) Psychopharmacology , vol.108 , pp. 159-169
    • Arnsten, A.F.T.1    Contant, T.A.2
  • 43
    • 0001803705 scopus 로고    scopus 로고
    • The alpha-2A nor-adrenergic agonist, guanfacine, improves visual object discrimination reversal performance in rhesus monkeys
    • &
    • Steere, J.C. & A.F.T. Arnsten. 1997. The alpha-2A nor-adrenergic agonist, guanfacine, improves visual object discrimination reversal performance in rhesus monkeys. Behav. Neurosci. 111 : 1 9.
    • (1997) Behav. Neurosci. , vol.111 , pp. 1-9
    • Steere, J.C.1    Arnsten, A.F.T.2
  • 44
    • 0033232504 scopus 로고    scopus 로고
    • Local infusion of alpha-1 adrenergic agonist into the prefrontal cortex impairs spatial working memory performance in monkeys
    • &
    • Mao, Z.-M., A.F.T. Arnsten & B.-M. Li. 1999. Local infusion of alpha-1 adrenergic agonist into the prefrontal cortex impairs spatial working memory performance in monkeys. Biol. Psychiatry 46 : 1259 1265.
    • (1999) Biol. Psychiatry , vol.46 , pp. 1259-1265
    • Mao, Z.-M.1    Arnsten, A.F.T.2    Li, B.-M.3
  • 45
    • 0346688564 scopus 로고    scopus 로고
    • The alpha(2A)-adrenergic agonist guanfacine improves visuomotor associative learning in monkeys
    • &
    • Wang, M., J.Z. Ji & B.M. Li. 2004. The alpha(2A)-adrenergic agonist guanfacine improves visuomotor associative learning in monkeys. Neuropsychopharmacology 29 : 86 92.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 86-92
    • Wang, M.1    Ji, J.Z.2    Li, B.M.3
  • 46
    • 0033136217 scopus 로고    scopus 로고
    • Guanfacine, but not clonidine, improves planning and working memory performance in humans
    • Jakala, P. et al. 1999. Guanfacine, but not clonidine, improves planning and working memory performance in humans. Neuropsychopharmacology 20 : 460 470.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 460-470
    • Jakala, P.1
  • 47
    • 0032826006 scopus 로고    scopus 로고
    • Alpha-2 adrenergic modulation of prefrontal cortical neuronal activity related to spatial working memory in monkeys
    • Li, B.-M. et al. 1999. Alpha-2 adrenergic modulation of prefrontal cortical neuronal activity related to spatial working memory in monkeys. Neuropsychopharmacology 21 : 601 610.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 601-610
    • Li, B.-M.1
  • 48
    • 34147105096 scopus 로고    scopus 로고
    • Alpha2A-adrenoceptor stimulation strengthens working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex
    • Wang, M. et al. 2007. Alpha2A-adrenoceptor stimulation strengthens working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129 : 397 410.
    • (2007) Cell , vol.129 , pp. 397-410
    • Wang, M.1
  • 49
    • 0028169105 scopus 로고
    • Delayed response deficit induced by local injection of the alpha-2 adrenergic antagonist yohimbine into the dorsolateral prefrontal cortex in young adult monkeys
    • &
    • Li, B.-M. & Z.-T. Mei. 1994. Delayed response deficit induced by local injection of the alpha-2 adrenergic antagonist yohimbine into the dorsolateral prefrontal cortex in young adult monkeys. Behav. Neural. Biol. 62 : 134 139.
    • (1994) Behav. Neural. Biol. , vol.62 , pp. 134-139
    • Li, B.-M.1    Mei, Z.-T.2
  • 50
    • 0037560036 scopus 로고    scopus 로고
    • Selective deficit in no-go performance induced by blockade of prefrontal cortical alpha2-adrenoceptors in monkeys
    • Ma, C.-L. et al. 2003. Selective deficit in no-go performance induced by blockade of prefrontal cortical alpha2-adrenoceptors in monkeys. Neuroreport 14 : 1013 1016.
    • (2003) Neuroreport , vol.14 , pp. 1013-1016
    • Ma, C.-L.1
  • 51
    • 11844287713 scopus 로고    scopus 로고
    • Locomotor hyperactivity induced by blockade of prefrontal cortical alpha-2-adrenoceptors in monkeys
    • &
    • Ma, C.-L., A.F.T. Arnsten & B.-M. Li. 2005. Locomotor hyperactivity induced by blockade of prefrontal cortical alpha-2-adrenoceptors in monkeys. Biol. Psychiatry 57 : 192 195.
    • (2005) Biol. Psychiatry , vol.57 , pp. 192-195
    • Ma, C.-L.1    Arnsten, A.F.T.2    Li, B.-M.3
  • 52
    • 0028817463 scopus 로고
    • An open trial of guanfacine in the treatment of attention deficit hyperactivity disorder
    • &
    • Hunt, R.D., A.F.T. Arnsten & M.D. Asbell. 1995. An open trial of guanfacine in the treatment of attention deficit hyperactivity disorder. J. Am. Acad. Child Adolesc. Psychiatry 34 : 50 54.
    • (1995) J. Am. Acad. Child Adolesc. Psychiatry , vol.34 , pp. 50-54
    • Hunt, R.D.1    Arnsten, A.F.T.2    Asbell, M.D.3
  • 53
    • 0034940566 scopus 로고    scopus 로고
    • Guanfacine in the treatment of children with tic disorders and ADHD: A placebo-controlled study
    • Scahill, L. et al. 2001. Guanfacine in the treatment of children with tic disorders and ADHD: a placebo-controlled study. Am. J. Psychiatry 158 : 1067 1074.
    • (2001) Am. J. Psychiatry , vol.158 , pp. 1067-1074
    • Scahill, L.1
  • 54
    • 0035100341 scopus 로고    scopus 로고
    • Comparing guanfacine and dextroamphetamine for the treatment of adult attention deficit-hyperactivity disorder
    • &
    • Taylor, F.B. & J. Russo. 2001. Comparing guanfacine and dextroamphetamine for the treatment of adult attention deficit-hyperactivity disorder. J. Clin. Psychopharm. 21 : 223 228.
    • (2001) J. Clin. Psychopharm. , vol.21 , pp. 223-228
    • Taylor, F.B.1    Russo, J.2
  • 55
    • 7444256727 scopus 로고    scopus 로고
    • Protein kinase C overactivity impairs prefrontal cortical regulation of working memory
    • Birnbaum, S.B. et al. 2004. Protein kinase C overactivity impairs prefrontal cortical regulation of working memory. Science 306 : 882 884.
    • (2004) Science , vol.306 , pp. 882-884
    • Birnbaum, S.B.1
  • 56
    • 0033004430 scopus 로고    scopus 로고
    • Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function
    • Arnsten, A.F.T. et al. 1999. Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function. Biol. Psychiatry 45 : 26 31.
    • (1999) Biol. Psychiatry , vol.45 , pp. 26-31
    • Arnsten, A.F.T.1
  • 57
    • 0342378052 scopus 로고    scopus 로고
    • The alpha-1 adrenergic agonist, cirazoline, impairs spatial working memory performance in aged monkeys
    • &
    • Arnsten, A.F.T. & J.D. Jentsch. 1997. The alpha-1 adrenergic agonist, cirazoline, impairs spatial working memory performance in aged monkeys. Pharmacol. Biochem. Behav. 58 : 55 59.
    • (1997) Pharmacol. Biochem. Behav. , vol.58 , pp. 55-59
    • Arnsten, A.F.T.1    Jentsch, J.D.2
  • 58
    • 0033232469 scopus 로고    scopus 로고
    • A role for norepinephrine in stress-induced cognitive deficits: Alpha-1-adrenoceptor mediation in prefrontal cortex
    • Birnbaum, S.G. et al. 1999. A role for norepinephrine in stress-induced cognitive deficits: alpha-1-adrenoceptor mediation in prefrontal cortex. Biol. Psychiatry 46 : 1266 1274.
    • (1999) Biol. Psychiatry , vol.46 , pp. 1266-1274
    • Birnbaum, S.G.1
  • 59
    • 0037315260 scopus 로고    scopus 로고
    • Prazosin reduces nightmares and other PTSD symptoms in combat veterans: A placebo-controlled study
    • Raskind, M.A. et al. 2003. Prazosin reduces nightmares and other PTSD symptoms in combat veterans: a placebo-controlled study. Am. J. Psychiatry 160 : 371 373.
    • (2003) Am. J. Psychiatry , vol.160 , pp. 371-373
    • Raskind, M.A.1
  • 60
    • 0033570745 scopus 로고    scopus 로고
    • Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness
    • &
    • Manji, H.K. & R.H. Lenox. 1999. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biol. Psychiatry 46 : 1328 1351.
    • (1999) Biol. Psychiatry , vol.46 , pp. 1328-1351
    • Manji, H.K.1    Lenox, R.H.2
  • 61
    • 12144286093 scopus 로고    scopus 로고
    • Support for RGS4 as a susceptibility gene for schizophrenia
    • Williams, N.M. et al. 2004. Support for RGS4 as a susceptibility gene for schizophrenia. Biol. Psychiatry 55 : 192 195.
    • (2004) Biol. Psychiatry , vol.55 , pp. 192-195
    • Williams, N.M.1
  • 62
    • 38349128462 scopus 로고    scopus 로고
    • A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
    • Baum, A.E. et al. 2008. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol. Psychiatry 13 : 197 207.
    • (2008) Mol. Psychiatry , vol.13 , pp. 197-207
    • Baum, A.E.1
  • 63
    • 0034666354 scopus 로고    scopus 로고
    • Pediatric mania: A developmental subtype of bipolar disorder?
    • Biederman, J. et al. 2000. Pediatric mania: a developmental subtype of bipolar disorder? Biol. Psychiatry 48 : 458 466.
    • (2000) Biol. Psychiatry , vol.48 , pp. 458-466
    • Biederman, J.1
  • 64
    • 29044438717 scopus 로고    scopus 로고
    • The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys
    • Ramos, B. et al. 2005. The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys. Biol. Psychiatry 58 : 894 900.
    • (2005) Biol. Psychiatry , vol.58 , pp. 894-900
    • Ramos, B.1
  • 65
    • 0026427253 scopus 로고
    • Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
    • Van Tol, H.H.M. et al. 1991. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 350 : 610 614.
    • (1991) Nature , vol.350 , pp. 610-614
    • Van Tol, H.H.M.1
  • 66
    • 0025452829 scopus 로고
    • Overlap of dopaminergic, adrenergic, and serotonergic receptors and complementarity of their subtypes in primate prefrontal cortex
    • &
    • Goldman-Rakic, P.S., M.S. Lidow & D.W. Gallager. 1990. Overlap of dopaminergic, adrenergic, and serotonergic receptors and complementarity of their subtypes in primate prefrontal cortex. J. Neurosci. 10 : 2125 2138.
    • (1990) J. Neurosci. , vol.10 , pp. 2125-2138
    • Goldman-Rakic, P.S.1    Lidow, M.S.2    Gallager, D.W.3
  • 67
    • 0028177440 scopus 로고
    • D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: Predominant and extrasynaptic localization in dendritic spines
    • Smiley, J.F. et al. 1994. D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines. Proc. Natl. Acad. Sci. USA 91 : 5720 5724.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5720-5724
    • Smiley, J.F.1
  • 68
    • 0035005945 scopus 로고    scopus 로고
    • D(1) dopamine receptors potentiate nmda-mediated excitability increase in layer V prefrontal cortical pyramidal neurons
    • &
    • Wang, J. & P. O'Donnell. 2001. D(1) dopamine receptors potentiate nmda-mediated excitability increase in layer V prefrontal cortical pyramidal neurons. Cereb. Cortex 11 : 452 462.
    • (2001) Cereb. Cortex , vol.11 , pp. 452-462
    • Wang, J.1    O'Donnell, P.2
  • 69
    • 0035793083 scopus 로고    scopus 로고
    • Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons
    • Seamans, J.K. et al. 2001. Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons. Proc. Natl. Acad. Sci. USA 98 : 301 306.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 301-306
    • Seamans, J.K.1
  • 70
    • 0842279614 scopus 로고    scopus 로고
    • Dopamine D1/D5 receptor modulates state-dependent switching of soma-dendritic Ca2+ potentials via differential protein kinase a and C activation in rat prefrontal cortical neurons
    • &
    • Young, C.E. & C.R. Yang. 2004. Dopamine D1/D5 receptor modulates state-dependent switching of soma-dendritic Ca2+ potentials via differential protein kinase A and C activation in rat prefrontal cortical neurons. J. Neurosci. 24 : 8 23.
    • (2004) J. Neurosci. , vol.24 , pp. 8-23
    • Young, C.E.1    Yang, C.R.2
  • 71
    • 0028172230 scopus 로고
    • Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys
    • Arnsten, A.F.T. et al. 1994. Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology 116 : 143 151.
    • (1994) Psychopharmacology , vol.116 , pp. 143-151
    • Arnsten, A.F.T.1
  • 72
    • 0034143246 scopus 로고    scopus 로고
    • Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex
    • Granon, S. et al. 2000. Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex. J. Neurosci. 20 : 1208 1215.
    • (2000) J. Neurosci. , vol.20 , pp. 1208-1215
    • Granon, S.1
  • 73
    • 0037291543 scopus 로고    scopus 로고
    • D1 dopamine receptors in the mouse prefrontal cortex: Immunocytochemical and cognitive neuropharmacological analyses
    • &
    • Lidow, M.S., P.-O. Koh & A.F.T. Arnsten. 2003. D1 dopamine receptors in the mouse prefrontal cortex: immunocytochemical and cognitive neuropharmacological analyses. Synapse 47 : 101 108.
    • (2003) Synapse , vol.47 , pp. 101-108
    • Lidow, M.S.1    Koh, P.-O.2    Arnsten, A.F.T.3
  • 74
    • 0030612013 scopus 로고    scopus 로고
    • Supranormal stimulation of dopamine D1 receptors in the rodent prefrontal cortex impairs spatial working memory performance
    • Zahrt, J. et al. 1997. Supranormal stimulation of dopamine D1 receptors in the rodent prefrontal cortex impairs spatial working memory performance. J. Neurosci. 17 : 8528 8535.
    • (1997) J. Neurosci. , vol.17 , pp. 8528-8535
    • Zahrt, J.1
  • 75
    • 0031945083 scopus 로고    scopus 로고
    • Noise stress impairs prefrontal cortical cognitive function in monkeys: Evidence for a hyperdopaminergic mechanism
    • &
    • Arnsten, A.F.T. & P.S. Goldman-Rakic. 1998. Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism. Arch. Gen. Psychiatry 55 : 362 369.
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 362-369
    • Arnsten, A.F.T.1    Goldman-Rakic, P.S.2
  • 76
    • 0037947438 scopus 로고    scopus 로고
    • Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine
    • Mattay, V.S. et al. 2003. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc. Natl. Acad. Sci. USA 100 : 6186 6191.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6186-6191
    • Mattay, V.S.1
  • 77
    • 33847191328 scopus 로고    scopus 로고
    • Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory
    • Vijayraghavan, S. et al. 2007. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat. Neurosci. 10 : 376 384.
    • (2007) Nat. Neurosci. , vol.10 , pp. 376-384
    • Vijayraghavan, S.1
  • 78
    • 0030662550 scopus 로고    scopus 로고
    • Effects of bromocriptine on human subjects depend on working memory capacity
    • &
    • Kimberg, D.Y., M. D'Esposito & M.J. Farah. 1997. Effects of bromocriptine on human subjects depend on working memory capacity. Neuroreport 8 : 3581 3585.
    • (1997) Neuroreport , vol.8 , pp. 3581-3585
    • Kimberg, D.Y.1    D'Esposito, M.2    Farah, M.J.3
  • 79
    • 0028085278 scopus 로고
    • The role of D1-dopamine receptors in working memory: Local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed response task
    • &
    • Sawaguchi, T. & P.S. Goldman-Rakic. 1994. The role of D1-dopamine receptors in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed response task. J. Neurophysiol. 71 : 515 528.
    • (1994) J. Neurophysiol. , vol.71 , pp. 515-528
    • Sawaguchi, T.1    Goldman-Rakic, P.S.2
  • 80
    • 0033952001 scopus 로고    scopus 로고
    • The effects of local application of D2 selective dopaminergic drugs into the medial prefrontal cortex of rats in a delayed spatial choice task
    • Druzin, M.Y. et al. 2000. The effects of local application of D2 selective dopaminergic drugs into the medial prefrontal cortex of rats in a delayed spatial choice task. Behav. Brain Res. 109 : 99 111.
    • (2000) Behav. Brain Res. , vol.109 , pp. 99-111
    • Druzin, M.Y.1
  • 81
    • 0842309863 scopus 로고    scopus 로고
    • Selective D2 receptor actions on the functional circuitry of working memory
    • &
    • Wang, M., S. Vijayraghavan & P.S. Goldman-Rakic. 2004. Selective D2 receptor actions on the functional circuitry of working memory. Science 303 : 853 856.
    • (2004) Science , vol.303 , pp. 853-856
    • Wang, M.1    Vijayraghavan, S.2    Goldman-Rakic, P.S.3
  • 82
    • 0037087327 scopus 로고    scopus 로고
    • Reduced communication between frontal and temporal lobes during talking in schizophrenia
    • Ford, J.M. et al. 2002. Reduced communication between frontal and temporal lobes during talking in schizophrenia. Biol. Psychiatry 51 : 485 492.
    • (2002) Biol. Psychiatry , vol.51 , pp. 485-492
    • Ford, J.M.1
  • 83
    • 0029887751 scopus 로고    scopus 로고
    • Localization of dopamine D4 receptors in GABAergic neurons of the primate brain
    • Mrzljak, L. et al. 1996. Localization of dopamine D4 receptors in GABAergic neurons of the primate brain. Nature 381 : 245 248.
    • (1996) Nature , vol.381 , pp. 245-248
    • Mrzljak, L.1
  • 84
    • 0036827035 scopus 로고    scopus 로고
    • Dopamine D4 receptors modulate GABAergic signaling in pyramidal neurons of prefrontal cortex
    • &
    • Wang, X., P. Zhong & Z. Yan. 2002. Dopamine D4 receptors modulate GABAergic signaling in pyramidal neurons of prefrontal cortex. J. Neurosci. 22 : 9185 9193.
    • (2002) J. Neurosci. , vol.22 , pp. 9185-9193
    • Wang, X.1    Zhong, P.2    Yan, Z.3
  • 85
    • 0033923995 scopus 로고    scopus 로고
    • Association and linkage of DRD4 and DRD5 with attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children
    • Tahir, E. et al. 2000. Association and linkage of DRD4 and DRD5 with attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children. Mol. Psychiatry 5 : 396 404.
    • (2000) Mol. Psychiatry , vol.5 , pp. 396-404
    • Tahir, E.1
  • 86
    • 0033653257 scopus 로고    scopus 로고
    • Linkage of the dopamine D4 receptor gene and attention-deficit/ hyperactivity disorder
    • Sunohara, G.A. et al. 2000. Linkage of the dopamine D4 receptor gene and attention-deficit/hyperactivity disorder. J. Am. Acad. Child Adolesc. Psychiatry 39 : 1537 1542.
    • (2000) J. Am. Acad. Child Adolesc. Psychiatry , vol.39 , pp. 1537-1542
    • Sunohara, G.A.1
  • 87
    • 0034006096 scopus 로고    scopus 로고
    • Through the looking glass: Differential noradrenergic modulation of prefrontal cortical function
    • Arnsten, A.F.T. 2000. Through the looking glass: differential noradrenergic modulation of prefrontal cortical function. Neural Plasticity 7 : 133 146.
    • (2000) Neural Plasticity , vol.7 , pp. 133-146
    • Arnsten, A.F.T.1
  • 88
    • 0034589070 scopus 로고    scopus 로고
    • Stress impairs PFC function in rats and monkeys: Role of dopamine D1 and norepinephrine alpha-1 receptor mechanisms
    • Arnsten, A.F.T. 2000. Stress impairs PFC function in rats and monkeys: role of dopamine D1 and norepinephrine alpha-1 receptor mechanisms. Prog. Brain Res. 126 : 183 192.
    • (2000) Prog. Brain Res. , vol.126 , pp. 183-192
    • Arnsten, A.F.T.1
  • 89
    • 20444412281 scopus 로고    scopus 로고
    • Molecular genetics of attention-deficit/hyperactivity disorder
    • Faraone, S.V. et al. 2005. Molecular genetics of attention-deficit/ hyperactivity disorder. Biol. Psychiatry 57 : 1313 1323.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1313-1323
    • Faraone, S.V.1
  • 90
    • 0032910655 scopus 로고    scopus 로고
    • Mapping susceptibility loci in attention deficit hyperactivity disorder: Preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children
    • Daly, G. et al. 1999. Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children. Mol. Psychiatry 4 : 192 196.
    • (1999) Mol. Psychiatry , vol.4 , pp. 192-196
    • Daly, G.1
  • 91
    • 21844452154 scopus 로고    scopus 로고
    • Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls
    • Durston, S. et al. 2005. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Mol. Psychiatry 10 : 678 685.
    • (2005) Mol. Psychiatry , vol.10 , pp. 678-685
    • Durston, S.1
  • 92
    • 20144383241 scopus 로고    scopus 로고
    • Support for association between ADHD and two candidate genes: NET1 and DRD1
    • Bobb, A.J. et al. 2005. Support for association between ADHD and two candidate genes: NET1 and DRD1. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 134 : 67 72.
    • (2005) Am. J. Med. Genet. B. Neuropsychiatr. Genet. , vol.134 , pp. 67-72
    • Bobb, A.J.1
  • 93
    • 0037040475 scopus 로고    scopus 로고
    • Further evidence for the association between attention-deficit/ hyperactivity disorder and the dopamine-beta-hydroxylase gene
    • Roman, T. et al. 2002. Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine-beta-hydroxylase gene. Am. J. Med. Genet. 114 : 154 158.
    • (2002) Am. J. Med. Genet. , vol.114 , pp. 154-158
    • Roman, T.1
  • 94
    • 33947264596 scopus 로고    scopus 로고
    • A polymorphism in the nor-epinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder
    • Kim, C.H. et al. 2006. A polymorphism in the nor-epinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder. Proc. Natl. Acad. Sci. USA 103 : 19164 19169.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 19164-19169
    • Kim, C.H.1
  • 95
    • 0034952023 scopus 로고    scopus 로고
    • Clinical and molecular genetics of ADHD and Tourette syndrome. Two related polygenic disorders
    • Comings, D.E. 2001. Clinical and molecular genetics of ADHD and Tourette syndrome. Two related polygenic disorders. Ann. N. Y. Acad. Sci. 931 : 50 83.
    • (2001) Ann. N. Y. Acad. Sci. , vol.931 , pp. 50-83
    • Comings, D.E.1
  • 96
    • 0041821753 scopus 로고    scopus 로고
    • Is the alpha-2A adrenergic receptor gene (ADRA2A) associated with attention-deficit/hyperactivity disorder?
    • Roman, T. et al. 2003. Is the alpha-2A adrenergic receptor gene (ADRA2A) associated with attention-deficit/hyperactivity disorder? Am. J. Med. Genet. B. Neuropsychiatr. Genet. 120 : 116 120.
    • (2003) Am. J. Med. Genet. B. Neuropsychiatr. Genet. , vol.120 , pp. 116-120
    • Roman, T.1
  • 97
    • 21244434801 scopus 로고    scopus 로고
    • Association and linkage of alpha-2A adrenergic receptor gene polymorphisms with childhood ADHD
    • Park, L. et al. 2005. Association and linkage of alpha-2A adrenergic receptor gene polymorphisms with childhood ADHD. Mol. Psychiatry 10 : 572 580.
    • (2005) Mol. Psychiatry , vol.10 , pp. 572-580
    • Park, L.1
  • 98
    • 33845409395 scopus 로고    scopus 로고
    • Possible involvement of alpha-2A adrenergic receptors in attention deficit hyperactivity disorder: Radioligand binding and polymorphism studies
    • Deupree, J.D. et al. 2006. Possible involvement of alpha-2A adrenergic receptors in attention deficit hyperactivity disorder: radioligand binding and polymorphism studies. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 141 : 877 884.
    • (2006) Am. J. Med. Genet. B. Neuropsychiatr. Genet. , vol.141 , pp. 877-884
    • Deupree, J.D.1
  • 99
    • 15044342166 scopus 로고    scopus 로고
    • Neurocognitive effects of methylphenidate in adult attention-deficit/ hyperactivity disorder
    • Turner, D.C. et al. 2005. Neurocognitive effects of methylphenidate in adult attention-deficit/hyperactivity disorder. Psychopharmacology 178 : 286 295.
    • (2005) Psychopharmacology , vol.178 , pp. 286-295
    • Turner, D.C.1
  • 100
    • 0030956352 scopus 로고    scopus 로고
    • Effects of methylphenidate on spatial working memory and planning in healthy young adults
    • Elliott, R. et al. 1997. Effects of methylphenidate on spatial working memory and planning in healthy young adults. Psychopharmacology 131 : 196 206.
    • (1997) Psychopharmacology , vol.131 , pp. 196-206
    • Elliott, R.1
  • 101
    • 0345489068 scopus 로고    scopus 로고
    • Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain
    • Mehta, M.A. et al. 2000. Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain. J. Neurosci. 20 : RC651 RC656.
    • (2000) J. Neurosci. , vol.20
    • Mehta, M.A.1
  • 102
    • 0037104803 scopus 로고    scopus 로고
    • Exposure of adolescent rats to oral methylphenidate: Preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine
    • &
    • Kuczenski, R. & D.S. Segal. 2002. Exposure of adolescent rats to oral methylphenidate: preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine. J. Neurosci. 22 : 7264 7271.
    • (2002) J. Neurosci. , vol.22 , pp. 7264-7271
    • Kuczenski, R.1    Segal, D.S.2
  • 103
    • 33750222300 scopus 로고    scopus 로고
    • Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function
    • Berridge, C.W. et al. 2006. Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function. Biol. Psychiatry 60 : 1111 1120.
    • (2006) Biol. Psychiatry , vol.60 , pp. 1111-1120
    • Berridge, C.W.1
  • 104
    • 27744605990 scopus 로고    scopus 로고
    • Methylphenidate improves prefrontal cortical cognitive function through a2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in attention deficit hyperactivity disorder
    • &
    • Arnsten, A.F.T. & A.G. Dudley. 2005. Methylphenidate improves prefrontal cortical cognitive function through a2 adrenoceptor and dopamine D1 receptor actions: relevance to therapeutic effects in attention deficit hyperactivity disorder. Behav. Brain Funct. (Biomed. Central) 1 : 2.
    • (2005) Behav. Brain Funct. (Biomed. Central) , vol.1 , pp. 2
    • Arnsten, A.F.T.1    Dudley, A.G.2
  • 105
    • 0036848458 scopus 로고    scopus 로고
    • Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: A potential mechanism for efficacy in attention deficit/hyperactivity disorder
    • Bymaster, F.P. et al. 2002. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology 27 : 699 711.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 699-711
    • Bymaster, F.P.1


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