Brain penetration and anticonvulsant efficacy of intranasal phenobarbital in rats

Epilepsia

Volumn 49, Issue 7, 2008, Pages 1142-1150

  Czapp, Marion ^a   Bankstahl, Jens P ^b   Zibell, Guido ^a   Potschka, Heidrun ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Antiepileptic drug; Intranasal; Kindling; Microdialysis; Phenobarbital

Indexed keywords

PHENOBARBITAL;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BRAIN HOMOGENATE; BRAIN REGION; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; CONTROLLED STUDY; DIALYSATE; DRUG ADMINISTRATION ROUTE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG PENETRATION; DRUG SYNTHESIS; FEMALE; HOMOGENATE; KINDLING; MAXIMUM PLASMA CONCENTRATION; MICRODIALYSIS; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; RAT;

ADMINISTRATION, INTRANASAL; AMYGDALA; ANIMALS; ANTICONVULSANTS; BRAIN; DRUG ADMINISTRATION ROUTES; FEMALE; INJECTIONS, INTRAVENOUS; KINDLING, NEUROLOGIC; MICRODIALYSIS; PHENOBARBITAL; RATS; RATS, WISTAR;

EID: 47249091315     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2008.01582.x     Document Type: Article

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