Intranasal angiotensin II directly influences central nervous regulation of blood pressure

American Journal of Hypertension

Volumn 11, Issue 8 I, 1998, Pages 971-977

  Derad, Inge ^a   Willeke, Karen ^a   Pietrowsky, Reinhard ^a   Born, Jan ^a   Fehm, Horst L ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Angiotensin II; Blood pressure; Central nervous system; Intranasal administration; Vasopressin

Indexed keywords

ANGIOTENSIN; NORADRENALIN; VASOPRESSIN;

ADULT; ARTICLE; BLOOD PRESSURE REGULATION; CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; INTRANASAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NEUROENDOCRINOLOGY; NEUROMODULATION; NORADRENALIN RELEASE; NORMAL HUMAN; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VASOPRESSIN RELEASE;

ADMINISTRATION, INTRANASAL; ADULT; ANGIOTENSIN II; BLOOD PRESSURE; BRAIN; CATECHOLAMINES; HEMODYNAMIC PROCESSES; HUMANS; MALE; VASOPRESSINS;

EID: 0031849276     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(98)00095-8     Document Type: Article

References (31)

1. Peach MJ: Physiological roles of angiotensin, in Meyerhofer J (ed): Chemistry of Biological Peptides: Proceedings of the Third American Peptide Symposium. Ann Arbor Science Publishers, Ann Arbor, MI, 1972, pp 477-493.
2. Dzau VJ, Ingelfinger JR, Pratt RE: Regulation of tissue renin and angiotensin gene expression. J Cardiovasc Pharmacol 1986;8(suppl 10):S11-S16.
3. Linz W, Wiemer G, Gohlke P, et al: Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol Rev 1995;47:25-49.
4. Höhle S, Blume A, Lebrun C, et al: Angiotensin receptors in the brain. Pharmacol Toxicol 1995;77:306-315.
5. Unger T, Chung O, Csikos T, et al: Angiotensin receptors. J Hypertens 1996;14:S95-S103.
6. Guo GB, Abboud FM: Angiotensin II attenuates baroreflex control of heart rate and sympathetic activity. Am J Physiol 1984;246:H80-H89.
7. Reid I: Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexs in regulation of blood pressure. Am J Physiol 1992;262:E763-E778.
8. Phillips M, Wielbo D, Gyurko R: Antisense inhibition of hypertension: a new strategy for renin-angiotensin candidate genes. Kidney Int 1994;46:1554-1556.
9. Goldsmith SR, Dodge-Brown D, Pentel P: Effects of infused norepinephrine and angiotensin-II on vasopressin levels in humans. Am J Med Sci 1988;295:513-516.
10. Unger T, Badoer E, Ganten D, et al: Brain angiotensin: pathways and pharmacology. Circulation 1988;77 (suppl I):I40-I54.
11. Steckelings U, Bottari S, Unger T: Angiotensin receptor subtypes in the brain. Trends Pharmacol Sci 1992;13: 365-368.
12. MacGregor DP, Murone C, Song K, et al: Angiotensin II receptor subtypes in the human central nervous system. Brain Res 1995;675:231-240.
13. Badoer E, Unger T, Ganten D: Role of endocrine brain in the control of hypertension. Angiotensin II and atrial natriuretic peptide in the brain, in Motta M (ed): Brain Endocrinology, 2nd ed. Raven Press, New York, 1991, pp 403-430.
14. Ferguson AV, Wall KM: Central actions of angiotensin in cardiovascular control: multiple roles for a single peptide. Can J Physiol Pharmacol 1991;70:779-785.
15. Culman J, Höhle S, Quadri F, et al: Angiotensin as neuromodulator/neurotransmitter in central control of body fluid and electrolyte homeostasis. Clin Exp Hypertens 1995;17:281-293.
16. Itaya S: Anterograde transsynaptic transport of WGA-HRP in rat olfactory pathways. Brain Res 1987;409:205-214.
17. Balin B, Broadwell R, Salcman M, et al: Avenues for the entry of peripherally administered protein to the central nervous system in mouse, rat, and squirrel monkey. J Comp Neurol 1986;251:260-280.
18. Riekkinen P, Legros J-J, Sennef C, et al: Penetration of DGAVP (Org 5667) across the blood-brain barrier in human subjects. Peptides 1987;8:261-265.
19. Kern W, Schiefer B, Schwarzenberg J, et al: Evidence for central nervous effects of corticotropin-releasing hormone on gastric acid secretion in humans. Clin Neuroendocrinol 1997;65:291-298.
20. Pietrowsky R, Strüben C, Mölle M, et al: Brain potential changes after intranasal vs. intravenous administration of vasopressin: evidence for a direct nose-brain pathway for peptide effects in humans. Biol Psychiatry 1996;39:332-340.
21. Linde M, Halabi A, Hinrichsen H, et al: Impedance cardiography in clinical pharmacology-advantages and limitations, in Winter UJ, Klocke RK, Kubicek WG, Niederlag W (eds): Thoracic Impedance Measurements in Clinical Cardiology. Thieme Verlag, Stuttgart, 1994, pp 81-84.
22. Janke W, Debus G: Die Eigenschaftswörterliste EWL. Eine mehrdimensionale Methode zur Beschreibung von Aspekten des Befindens. Verlag für Psychologie Hogrefe, Göttingen, 1988.
23. Veltmar A, Culman J, Qadri F, et al: Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release. J Pharmacol Exp Ther 1992;263:1253-1260.
24. Steckelings U, Lebrun C, Qadri F, et al: Role of brain angiotensin in cardiovascular regulation. J Cardiovasc Pharmacol 1992;19(suppl 6):S72-S79.
25. Qadri F, Badoer E, Stadier T, et al: Angiotensin II-induced noradrenaline release from anterior hypothalamus in conscious rats: a brain microdialysis study. Brain Res 1991;563:137-141.
26. Stadler T, Veltmar A, Qadri F, et al: Angiotensin II evokes noradrenaline release from the paraventricular nucleus in conscious rats. Brain Res 1992;569:117-122.
27. Mendelsohn FAO, Doyle AE, Gray GW: Lack of response of sympathetic nervous system to angiotensin infusion. Lancet 1980;i:492-493.
28. Mace PJE, Watson RDS, Skan W, et al: Inhibition of the baroreceptor heart reflex by angiotensin II in normal man. Cardiovasc Res 1985;19:525-527.
29. Seidelin PH, Coutie WJR, Struthers AD: The effect of angiotensin II on endogenous noradrenaline release in man. Br J Clin Pharm 1987;24:699-704.
30. Phillips P, Bretherton M, Risvanis J, et al: Effects of drinking on thirst and vasopressin in dehydrated elderly men. Am J Physiol 1993;264:R877-881.
31. Dahl A, Hadley W: Nasal cavity enzymes involved in xenobiotic metabolism effects on the toxicity of inhalants. Crit Rev Toxicol 1991;21:345-372.