Discovery and structure - Activity relationship of the first non- peptide competitive human glucagon receptor antagonists

Journal of Medicinal Chemistry

Volumn 41, Issue 26, 1998, Pages 5150-5157

  Madsen, Peter ^a   Knudsen, Lotte B ^a   Wiberg, Finn C ^a   Carr, Richard D ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

2 (BENZIMIDAZOL 2 YLTHIO) 1 (3,4 DIHYDROXYPHENYL) 1 ETHANONE; 6,7 DICHLORO 2 [N (3 DIMETHYLAMINOPROPYL) N METHYLAMINO] 3 STYRYLQUINOXALINE; ADENYLATE CYCLASE; CATECHOL; GLUCAGON; GLUCAGON RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HETEROCYCLIC AMINE; MONOCLONAL ANTIBODY; NCC 921687; NEUTRALIZING ANTIBODY; SECRETIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; GLUCAGON BLOOD LEVEL; GLUCONEOGENESIS; GLYCOGENOLYSIS; HYPERGLYCEMIA; NON INSULIN DEPENDENT DIABETES MELLITUS; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZIMIDAZOLES; CELL LINE; CRICETINAE; HUMANS; RECEPTORS, GLUCAGON; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032542247     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9810304     Document Type: Article

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