Glucose stimulates glucagon release in single rat α-cells by mechanisms that mirror the stimulus-secretion coupling in β-cells

Endocrinology

Volumn 146, Issue 11, 2005, Pages 4861-4870

  Olsen, Hervør Lykke ^a,d   Theander, Sten ^c   Bokvist, Krister ^a   Buschard, Karsten ^b   Wollheim, Claes B ^c   Gromada, Jesper ^a  

^a Lilly Research Laboratories   (Germany)

^b Rigshospitalet   (Denmark)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^d Sophion Bioscience A/S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AZIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CALCIUM ION; DIAZOXIDE; GLUCAGON; GLUCOSE; MANNOHEPTULOSE; NIFEDIPINE; OMEGA CONOTOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM ION; SNX 482; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN; TETRYLAMMONIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; CORRELATION ANALYSIS; EXOCYTOSIS; GLUCAGON RELEASE; GLYCOLYSIS; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; DIAZOXIDE; ELECTRIC STIMULATION; ENZYME INHIBITORS; EXOCYTOSIS; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE; INTRACELLULAR MEMBRANES; MALE; OSMOLAR CONCENTRATION; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM AZIDE; SODIUM CHANNEL BLOCKERS; THAPSIGARGIN;

EID: 26844556580     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0800     Document Type: Article

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