Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels

Journal of General Physiology

Volumn 110, Issue 3, 1997, Pages 217-228

  Gromada, Jesper ^a   Bokvist, Krister ^a   Ding, Wei Guang ^a   Barg, Sebastian ^a,c   Buschard, Karsten ^b   Renström, Erik ^a,c   Rorsman, Patrik ^a,c  

^a NOVO NORDISK A S   (Denmark)

^b Department of Rheumatology and the Osteoporosis Research Centre   (Denmark)

^c Dept of Physiology and Neuroscience ^*  (Sweden)

Author keywords

Ca2+; Glucagon; Secretion

Indexed keywords

ADRENALIN; BETA ADRENERGIC RECEPTOR; CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCAGON;

ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL GRANULE; CONTROLLED STUDY; DIABETES MELLITUS; ELECTROPHYSIOLOGY; EXOCYTOSIS; GLUCAGON RELEASE; HORMONAL REGULATION; MALE; NONHUMAN; PANCREAS ISLET ALPHA CELL; RAT;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOPLASM; ELECTRIC CONDUCTIVITY; ENZYME ACTIVATION; EPINEPHRINE; EXOCYTOSIS; GLUCAGON; GLUCOSE; ISLETS OF LANGERHANS; MALE; OSMOLAR CONCENTRATION; RATS; RATS, INBRED LEW; RECEPTORS, ADRENERGIC, BETA;

EID: 0030967933     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.110.3.217     Document Type: Article

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