Parasympathetic innervation and function of endocrine pancreas requires the glial cell line-derived factor family receptor α2 (GFRα2)

Diabetes

Volumn 54, Issue 5, 2005, Pages 1324-1330

  Rossi, Jari ^a   Santamäki, Paavo ^a   Airaksinen, Matti S ^a   Herzig, Karl Heinz ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED FAMILY RECEPTOR ALPHA 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEURTURIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FUNCTION; ENDOCRINE PANCREAS FUNCTION TEST; ENZYME DEFICIENCY; GLIA CELL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; HORMONE RELEASE; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; INSULIN RESPONSE; INTESTINE INNERVATION; LANGERHANS CELL; MOUSE; NONHUMAN; PANCREAS FUNCTION; PARASYMPATHETIC INNERVATION; PRIORITY JOURNAL; PROTEIN FAMILY; SCHWANN CELL; VAGUS NERVE STIMULATION;

ANIMALS; BLOOD GLUCOSE; CELL LINE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; GLUCOSE TOLERANCE TEST; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; NEUROGLIA; PANCREATIC POLYPEPTIDE; PARASYMPATHETIC NERVOUS SYSTEM; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTOR PROTEIN-TYROSINE KINASES; VAGUS NERVE;

EID: 17844375114     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.54.5.1324     Document Type: Article

References (44)

1. Havel PJ, Taborsky GJJ: The contribution of the autonomic nervous system to changes of glucagon and insulin secretion during hypoglycemic stress. Endocr Rev 10:332-350, 1989
2. Brunicardi FC, Shavelle DM, Andersen DK: Neural regulation of the endocrine pancreas. Int J Pancreatol 18:177-195, 1995
3. Ahrén B: Autonomic regulation of islet hormone secretion: implications for health and disease. Diabetologia 43:393-410, 2000
4. Gilon P, Henquin JC: Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Endocr Rev 22:565-604, 2001
5. Miller RE: Pancreatic neuroendocrinology: peripheral neural mechanisms in the regulation of the islets of Langerhans. Endocr Rev 2:471-494, 1981
6. Kirchgessner AL, Gershon MD: Innervation of the pancreas by neurons in the gut. J Neurosci 10:1626-1642, 1990
7. Kirchgessner AL, Pintar JE: Guinea pig pancreatic ganglia: projections, transmitter content, and the type-specific localization of monoamine oxidase. J Comp Neurol 305:613-631, 1991
8. Schusdziarra V, Bender H, Torres A, Pfeiffer EF: Cholinergic mechanisms in intestinal phase insulin secretion in rats. Regul Pept 6:81-87, 1983
9. Greenberg GR, Pokol-Daniel S: Neural modulation of glucose-dependent insulinotropic peptide (GIP) and insulin secretion in conscious dogs. Pancreas 9:531-535, 1994
10. D'Alessio DA, Kieffer TJ, Taborsky GJ Jr, Havel PJ: Activation of the parasympathetic nervous system is necessary for normal meal-induced insulin secretion in rhesus macaques. J Clin Endocrinol Metab 86:1253-1259, 2001
11. Edwards RH, Rutter WJ, Hanahan D: Directed expression of NGF to pancreatic beta cells in transgenic mice leads to selective hyperinnervation of the islets. Cell 58:161-170, 1989
12. Glebova NO, Ginty DD: Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J Neurosci 24:743-751, 2004
13. Airaksinen MS, Saarma M: The GDNF family: signalling, biological functions and therapeutic value. Nature Rev Neurosci 3:383-394, 2002
14. Rossi J, Herzig KH, Voikar V, Hiltunen PH, Segerstrale M, Airaksinen MS: Alimentary tract innervation deficits and dysfunction in mice lacking GDNF family receptor α2. J Clin Invest 112:707-716, 2003
15. Rossi J, Luukko K, Poteryaev D, Laurikainen A, Sun Y-F, Laakso T, Eerikäinen S, Tuominen R, Lakso M, Rauvala H, Arumäe U, Saarma M, Airaksinen MS: Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFRα2, a functional neurturin receptor. Neuron 22:243-252, 1999
16. Simonsson E, Ahren B: Potentiated beta-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice. Eur J Pharmacol 350:243-250, 1998
17. Havel PJ, Akpan JO, Curry DL, Stern JS, Gingerich RL, Ahren B: Autonomic control of pancreatic polypeptide and glucagon secretion during neuroglucopenia and hypoglycemia in mice. Am J Physiol 265:R246-R254, 1993
18. Karlsson S, Scheurink AJ, Ahren B: Gender difference in the glucagon response to glucopenic stress in mice. Am J Physiol Regul Integr Comp Physiol 282:R281-R288, 2002
19. Ushiki T, Watanabe S: Distribution and ultrastructure of the autonomic nerves in the mouse pancreas. Microsc Res Tech 37:399-406, 1997
20. Sunami E, Kanazawa H, Hashizume H, Takeda M, Hatakeyama K, Ushiki T: Morphological characteristics of Schwann cells in the islets of Langerhans of the murine pancreas. Arch Histol Cytol 64:191-201, 2001
21. Sternini C, Anderson K: Calcitonin gene-related peptide-containing neurons supplying the rat digestive system: differential distribution and expression pattern. Somatosens Mot Res 9:45-59, 1992
22. Won MH, Park HS, Jeong YG, Park HJ: Afferent innervation of the rat pancreas: retrograde tracing and immunohistochemistry in the dorsal root ganglia. Pancreas 16:80-87, 1998
23. Plenderleith MB, Snow PJ: The plant lectin Bandeiraea simplicifolia I-B4 identifies a subpopulation of small diameter primary sensory neurones which innervate the skin in the rat. Neurosci Lett 159:17-20, 1993
24. Neuhuber WL: Vagal afferent fibers almost exclusively innervate islets in the rat pancreas as demonstrated by anterograde tracing. J Auton Nerv Syst 29:13-18, 1989
25. Kashiba H, Uchida Y, Senba E: Distribution and colocalization of NGF and GDNF family ligand receptor mRNAs in dorsal root and nodose ganglion neurons of adult rats. Brain Res Mol Brain Res 110:52-62, 2003
26. Su HC, Bishop AE, Power RF, Hamada Y, Polak JM: Dual intrinsic and extrinsic origins of CGRP- and NPY-immunoreactive nerves of rat gut and pancreas. J Neurosci 7:2674-2687, 1987
27. Bilak MM, Shifrin DA, Corse AM, Bilak SR, Kuncl RW: Neuroprotective utility and neurotrophic action of neurturin in postnatal motor neurons: comparison with GDNF and persephin. Mol Cell Neurosci 13:326-336, 1999
28. Brodski C, Schaubmar A, Dechant G: Opposing functions of GDNF and NGF in the development of cholinergic and noradrenergic sympathetic neurons. Mol Cell Neurosci 19:528-538, 2002
29. Nishi S, Seino Y, Ishida H, Seno M, Taminato T, Sakurai H, Imura H: Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat. J Clin Invest 79:1191-1196, 1987
30. Lundquist I: Cholinergic muscarinic effects on insulin release in mice. Pharmacology 25:338-347, 1982
31. Karlsson S, Bood M, Ahren B: The mechanism of 2-deoxy-glucose-induced insulin secretion in the mouse. J Auton Pharmacol 7:135-144, 1987
32. Robertson RP: Islet transplantation as a treatment for diabetes: a work in progress. N Engl J Med 350:694-705, 2004
33. Reimer MK, Mokshagundam SP, Wyler K, Sundler F, Ahren B, Stagner JI: Local growth factors are beneficial for the autonomic reinnervation of transplanted islets in rats. Pancreas 26:392-397, 2003
34. Karlsson S, Ahren B: Contribution of adrenergic nerves and the adrenals to 2-deoxy-D-glucose-induced insulin and glucagon secretion in the mouse. Int J Pancreatol 10:207-215, 1991
35. Pascoe WS, Smythe GA, Storlien LH: 2-deoxy-D-glucose-induced hyperglycemia: role for direct sympathetic nervous system activation of liver glucose output. Brain Res 505:23-28, 1989
36. Henquin JC, Ravier MA, Nenquin M, Jonas JC, Gilon P: Hierarchy of the beta-cell signals controlling insulin secretion. Eur J Clin Invest 33:742-750, 2003
37. Curry DL, Bennett LL, Grodsky GM: Dynamics of insulin secretion by the perfused rat pancreas. Endocrinology 83:572-584, 1968
38. Grodsky GM: Kinetics of insulin secretion. In Diabetes Mellitus. LeRoith D, Taylor SI, Olefsky JM, Eds. Philadelphia, Lippincott Williams and Wilkins, 2000, p. 2-11
39. Bruce DG, Storlien LH, Furler SM, Chisholm DJ: Cephalic phase metabolic responses in normal weight adults. Metabolism 36:721-725, 1987
40. Ahren B, Holst JJ: The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia. Diabetes 50:1030-1038, 2001
41. Bruttomesso D, Pianta A, Mari A, Valerio A, Marescotti MC, Avogaro A, Tiengo A, Del Prato S: Restoration of early rise in plasma insulin levels improves the glucose tolerance of type 2 diabetic patiente. Diabetes 48:99-105, 1999
42. Fukudo S, Virnelli S, Kuhn CM, Cochrane C, Feinglos MN, Surwit RS: Muscarinic stimulation and antagonism and glucoregulation in nondiabetic and obese hyperglycemic mice. Diabetes 38:1433-1438, 1989
43. Rohner-Jeanrenaud F: A neuroendocrine reappraisal of the dual-centre hypothesis: its implications for obesity and insulin resistance. Int J Obes Relat Metab Disord 19:517-534, 1995
44. Del Rio G, Procopio M, Bondi M, Marrama P, Menozzi R, Oleandri SE, Grottoli S, Maccario M, Velardo A, Ghigo E: Cholinergic enhancement by pyridostigmine increases the insulin response to glucose load in obese patients but not in normal subjects. Int J Obes Relat Metab Disord 21:1111-1114, 1997