-
1
-
-
0031896882
-
Active apical secretory efflux of the HTV protease inhibitors saquinavir and ritonavir in Caco-2 cell mono-layers
-
Alsenz J, Steffen H, Alex R (1998) Active apical secretory efflux of the HTV protease inhibitors saquinavir and ritonavir in Caco-2 cell mono-layers. Pharm Res 15: 423-428.
-
(1998)
Pharm Res
, vol.15
, pp. 423-428
-
-
Alsenz, J.1
Steffen, H.2
Alex, R.3
-
2
-
-
0346216088
-
Development of a 7-day, 96-well Caco-2 permeability assay with high-throughput direct UV compound analysis
-
Alsenz J, Haenel E (2003) Development of a 7-day, 96-well Caco-2 permeability assay with high-throughput direct UV compound analysis. Pharm Res 20: 1961-1969.
-
(2003)
Pharm Res
, vol.20
, pp. 1961-1969
-
-
Alsenz, J.1
Haenel, E.2
-
3
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM (1999) Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 39: 361-398.
-
(1999)
Annu Rev Pharmacol Toxicol
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
4
-
-
0031834404
-
P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: The influence of cul-turing conditions and drug exposure on P-gp expression levels
-
Anderle P, Niederer E, Rubas W, Hilgendorf C, Spahn-Langguth H, Wun-derli-Allenspach H, Merkle HP, Langguth P (1998) P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of cul-turing conditions and drug exposure on P-gp expression levels. J Pharm Sci 87: 757-762.
-
(1998)
J Pharm Sci
, vol.87
, pp. 757-762
-
-
Anderle, P.1
Niederer, E.2
Rubas, W.3
Hilgendorf, C.4
Spahn-Langguth, H.5
Wun-derli-Allenspach, H.6
Merkle, H.P.7
Langguth, P.8
-
5
-
-
0035286778
-
Caco-2 monolayers in experimental and theoretical predictions of drug transport
-
Artursson P, Palm K, Luthman K (2001) Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv Drug Deliv Rev 46: 27-43.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 27-43
-
-
Artursson, P.1
Palm, K.2
Luthman, K.3
-
6
-
-
0002425059
-
Studying transport processes in absorptive epithelia
-
Shaw AJ ed, Oxford University Press, pp
-
Artursson P, Karlsson J, Ocklind G, Schipper N (1996) Studying transport processes in absorptive epithelia. In: Shaw AJ (ed.) Epithelial Cell Culture - A Practical Approach, Oxford University Press, pp. 111-133.
-
(1996)
Epithelial Cell Culture - A Practical Approach
, pp. 111-133
-
-
Artursson, P.1
Karlsson, J.2
Ocklind, G.3
Schipper, N.4
-
7
-
-
0030588644
-
The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development
-
Bailey CA, Bryla P, Malick AW (1996) The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development. Adv Drug Deliv Rev 22: 85-103.
-
(1996)
Adv Drug Deliv Rev
, vol.22
, pp. 85-103
-
-
Bailey, C.A.1
Bryla, P.2
Malick, A.W.3
-
8
-
-
33646640645
-
-
Balimane PV, Han YH, Chong S (2006) Current industrial practices of assessing permeability and P-glycoprotein interaction. AAPS J. 8: El-13.
-
Balimane PV, Han YH, Chong S (2006) Current industrial practices of assessing permeability and P-glycoprotein interaction. AAPS J. 8: El-13.
-
-
-
-
9
-
-
2942682950
-
Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery
-
Balimane PV, Patel K, Marino A, Chong S (2004) Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery. Eur J Pharm Biopharm 58: 99-105.
-
(2004)
Eur J Pharm Biopharm
, vol.58
, pp. 99-105
-
-
Balimane, P.V.1
Patel, K.2
Marino, A.3
Chong, S.4
-
10
-
-
0030909506
-
The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells
-
Briske-Anderson MJ, Finley JW, Newman SM (1997) The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells. Proc Soc Exp Biol Med 214: 248-257.
-
(1997)
Proc Soc Exp Biol Med
, vol.214
, pp. 248-257
-
-
Briske-Anderson, M.J.1
Finley, J.W.2
Newman, S.M.3
-
11
-
-
25844530789
-
Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs
-
Choi JS, Jin MJ, Han, HK (2005) Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs. J Pharm Pharmacol 57: 1185-1189.
-
(2005)
J Pharm Pharmacol
, vol.57
, pp. 1185-1189
-
-
Choi, J.S.1
Jin, M.J.2
Han, H.K.3
-
12
-
-
3242686014
-
Rapid induction of P-glyco-protein expression by high permeability compounds in colonic cells in vitro: A possible source of transporter mediated drug interactions?
-
Collett A, Tanianis-Hughes J, Warhurst G (2004) Rapid induction of P-glyco-protein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions? Biochem Pharmacol 68: 783-790.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 783-790
-
-
Collett, A.1
Tanianis-Hughes, J.2
Warhurst, G.3
-
13
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-gly-coprotein) in human normal and tumor tissues
-
Cordon-Cardo C, O'Brien JP, Boccia J, Casals D, Bertino JR, Melamed MR (1990) Expression of the multidrug resistance gene product (P-gly-coprotein) in human normal and tumor tissues. J Histochem Cytochem 38: 1277-1287.
-
(1990)
J Histochem Cytochem
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Boccia, J.3
Casals, D.4
Bertino, J.R.5
Melamed, M.R.6
-
14
-
-
0032885452
-
Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein
-
Doppenschmitt S, Spahn-Langguth H, Regardh CG, Langguth P (1999) Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein. J Pharm Sci 88: 1067-1072.
-
(1999)
J Pharm Sci
, vol.88
, pp. 1067-1072
-
-
Doppenschmitt, S.1
Spahn-Langguth, H.2
Regardh, C.G.3
Langguth, P.4
-
15
-
-
9044252313
-
CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells
-
Gan L, Moseley M, Khosla B, Augustijns P, Bradshaw T, Hendren R, Thakker D (1996) CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells. Drug Metab Dispos 24: 344-349.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 344-349
-
-
Gan, L.1
Moseley, M.2
Khosla, B.3
Augustijns, P.4
Bradshaw, T.5
Hendren, R.6
Thakker, D.7
-
16
-
-
0034960419
-
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells
-
Gao J, Murase O, Schowen RL, Aube J, Borchardt RT (2001) A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharm Res 18: 171-176.
-
(2001)
Pharm Res
, vol.18
, pp. 171-176
-
-
Gao, J.1
Murase, O.2
Schowen, R.L.3
Aube, J.4
Borchardt, R.T.5
-
17
-
-
0027484689
-
Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles
-
Garrigos M, Belehradek J Jr, Mir LM, Orlowski S (1993) Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles. Biochem Biophys Res Commun 196: 1034-1041.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 1034-1041
-
-
Garrigos, M.1
Belehradek Jr, J.2
Mir, L.M.3
Orlowski, S.4
-
18
-
-
0041386827
-
Role of ADME characteristics in drug discovery and their in silico evaluation: In silico screening of chemicals for their metabolic stability
-
Gombar VK, Silver IS, Zhao Z (2003) Role of ADME characteristics in drug discovery and their in silico evaluation: in silico screening of chemicals for their metabolic stability. Curr Top Med Chem 3: 1205-1225.
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 1205-1225
-
-
Gombar, V.K.1
Silver, I.S.2
Zhao, Z.3
-
19
-
-
0033957756
-
Influence of P-glycoprotein on the transport and metabolism of indinavir in Caco-2 cells expressing cytochrome P-450 3A4
-
Hochman JH, Chiba M, Nishime J, Yamazaki M, Lin JH (2000) Influence of P-glycoprotein on the transport and metabolism of indinavir in Caco-2 cells expressing cytochrome P-450 3A4. J Pharmacol Exp Ther 292: 310-318.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 310-318
-
-
Hochman, J.H.1
Chiba, M.2
Nishime, J.3
Yamazaki, M.4
Lin, J.H.5
-
20
-
-
0029896241
-
Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers
-
Hosoya KI, Kim KJ, Lee VH (1996) Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers. Pharm Res 13: 885-890.
-
(1996)
Pharm Res
, vol.13
, pp. 885-890
-
-
Hosoya, K.I.1
Kim, K.J.2
Lee, V.H.3
-
21
-
-
0025668535
-
Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2)
-
Hu M, Borchardt RT (1990) Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2). Pharm Res 7: 1313-1319.
-
(1990)
Pharm Res
, vol.7
, pp. 1313-1319
-
-
Hu, M.1
Borchardt, R.T.2
-
22
-
-
0343488673
-
Intestinal secretion of drugs. The role of P-glycoprotein and related drug efflux systems in limiting oral drug absorption
-
Hunter J, Hirst BH (1997) Intestinal secretion of drugs. The role of P-glycoprotein and related drug efflux systems in limiting oral drug absorption. Adv Drug Deliv Rev 25: 129-157.
-
(1997)
Adv Drug Deliv Rev
, vol.25
, pp. 129-157
-
-
Hunter, J.1
Hirst, B.H.2
-
24
-
-
0034194476
-
Regulation of volume-activated chloride channels by P-glycoprotein: Phosphorylau'on has the final say!
-
Idriss HT, Hannun YA, Boulpaep E, Basavappa S (2000) Regulation of volume-activated chloride channels by P-glycoprotein: phosphorylau'on has the final say! J Physiol 524: 629-636.
-
(2000)
J Physiol
, vol.524
, pp. 629-636
-
-
Idriss, H.T.1
Hannun, Y.A.2
Boulpaep, E.3
Basavappa, S.4
-
25
-
-
33751221603
-
In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions
-
Kreander K, Galkin A, Vuorela S, Tammela P, Laitinen L, Heinonen M, Vuorela P (2006) In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions. J Pharm Pharmacol 58: 1545-1552.
-
(2006)
J Pharm Pharmacol
, vol.58
, pp. 1545-1552
-
-
Kreander, K.1
Galkin, A.2
Vuorela, S.3
Tammela, P.4
Laitinen, L.5
Heinonen, M.6
Vuorela, P.7
-
26
-
-
6344230038
-
Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers
-
Laitinen LA, Tammela PS, Galkin A, Vuorela HJ, Marvola ML, Vuorela PM (2004) Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers. Pharm Res 21: 1904-1916.
-
(2004)
Pharm Res
, vol.21
, pp. 1904-1916
-
-
Laitinen, L.A.1
Tammela, P.S.2
Galkin, A.3
Vuorela, H.J.4
Marvola, M.L.5
Vuorela, P.M.6
-
27
-
-
0030023536
-
Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in vitro and human jejunum in vivo
-
Lennernäs H, Palm K, Fagerholm U, Artursson P (1996) Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in vitro and human jejunum in vivo. Int J Pharm 127: 103-107.
-
(1996)
Int J Pharm
, vol.127
, pp. 103-107
-
-
Lennernäs, H.1
Palm, K.2
Fagerholm, U.3
Artursson, P.4
-
28
-
-
23844440624
-
Strategies for targeting the multidrug resistance-1 (MDRl)/P-gp transporter in human malignancies
-
Mahadevan D, Shirahatti N (2005) Strategies for targeting the multidrug resistance-1 (MDRl)/P-gp transporter in human malignancies. Curr Cancer Drug Targets 5: 445-455.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 445-455
-
-
Mahadevan, D.1
Shirahatti, N.2
-
29
-
-
0027328896
-
Interaction of the 43 kd postsynaptic protein with all subunits of the muscle nicotinic acetylcholine receptor
-
Maimone MM, Merlie JP (1993) Interaction of the 43 kd postsynaptic protein with all subunits of the muscle nicotinic acetylcholine receptor. Neuron 11:53-66.
-
(1993)
Neuron
, vol.11
, pp. 53-66
-
-
Maimone, M.M.1
Merlie, J.P.2
-
30
-
-
19344367311
-
Validation of the 96 well Caco-2 cell culture model for high throughput permeability assessment of discovery compounds
-
Marino AM, Yarde M, Patel H, Chong S, Balimane PV (2005) Validation of the 96 well Caco-2 cell culture model for high throughput permeability assessment of discovery compounds. Int J Pharm 297: 235-241.
-
(2005)
Int J Pharm
, vol.297
, pp. 235-241
-
-
Marino, A.M.1
Yarde, M.2
Patel, H.3
Chong, S.4
Balimane, P.V.5
-
31
-
-
0035724848
-
Optimizing Caco-2 cell monolayers to increase throughput in drug intestinal absorption analysis
-
Markowska M, Oberle R, Juzwin S, Hsu CP, Gryszkiewicz M, Streeter AJ (2001) Optimizing Caco-2 cell monolayers to increase throughput in drug intestinal absorption analysis. J Pharmacol Toxicol Methods 46: 51-55.
-
(2001)
J Pharmacol Toxicol Methods
, vol.46
, pp. 51-55
-
-
Markowska, M.1
Oberle, R.2
Juzwin, S.3
Hsu, C.P.4
Gryszkiewicz, M.5
Streeter, A.J.6
-
32
-
-
46849122439
-
-
Millipore Corporation
-
™ Caco-2. 2002.
-
(2002)
™ Caco-2
-
-
-
33
-
-
0028284288
-
Characterization of rhodamine 123 binding to P-glycoprotein in human multidrug-resistant cells
-
Nare B, Prichard RK, Georges E (1994) Characterization of rhodamine 123 binding to P-glycoprotein in human multidrug-resistant cells. Mol Pharmacol 45: 1145-1152.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 1145-1152
-
-
Nare, B.1
Prichard, R.K.2
Georges, E.3
-
34
-
-
33749036875
-
What kinds of substrates show P-glycopro-tein-dependent intestinal absorption? Comparison of verapamil with vin-blastine
-
Ogihara T, Kamiya M, Ozawa M, Fujita T, Yamamoto A, Yamashita S, Ohnishi S, Isomura Y (2006) What kinds of substrates show P-glycopro-tein-dependent intestinal absorption? Comparison of verapamil with vin-blastine. Drug Metab Pharmacokinet 21: 238-244.
-
(2006)
Drug Metab Pharmacokinet
, vol.21
, pp. 238-244
-
-
Ogihara, T.1
Kamiya, M.2
Ozawa, M.3
Fujita, T.4
Yamamoto, A.5
Yamashita, S.6
Ohnishi, S.7
Isomura, Y.8
-
35
-
-
0030035535
-
Effects of steroids and verapamil on P-glycoprotein ATPase activity: Progesterone, desoxycorticosterone, corticosterone and verapamil are mutually non-exclusive modulators
-
Orlowski S, Mir LM, Belehradek J Jr, Garrigos M (1996) Effects of steroids and verapamil on P-glycoprotein ATPase activity: progesterone, desoxycorticosterone, corticosterone and verapamil are mutually non-exclusive modulators. Biochem J 317: 515-522.
-
(1996)
Biochem J
, vol.317
, pp. 515-522
-
-
Orlowski, S.1
Mir, L.M.2
Belehradek Jr, J.3
Garrigos, M.4
-
36
-
-
33644684597
-
Investigation of vesicle electroki-netic chromatography as an in vitro assay for the estimation of intestinal permeability of pharmaceutical drag candidates
-
Pascoe RJ, Masucci JA, Foley JP (2006) Investigation of vesicle electroki-netic chromatography as an in vitro assay for the estimation of intestinal permeability of pharmaceutical drag candidates. Electrophoresis 27: 793-804.
-
(2006)
Electrophoresis
, vol.27
, pp. 793-804
-
-
Pascoe, R.J.1
Masucci, J.A.2
Foley, J.P.3
-
38
-
-
0034763005
-
Rational use of in vitro P-glycoprotein assays in drag discovery
-
Polli JW, Wring SA, Humphreys JE, Huang L, Morgan JB, Webster LO, Serabjit-Singh CS (2001) Rational use of in vitro P-glycoprotein assays in drag discovery. J Pharmacol Exp Ther 299: 620-628.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 620-628
-
-
Polli, J.W.1
Wring, S.A.2
Humphreys, J.E.3
Huang, L.4
Morgan, J.B.5
Webster, L.O.6
Serabjit-Singh, C.S.7
-
39
-
-
36549003218
-
Transport properties of bovine and reindeer beta-lactoglobulin in the Caco-2 cell model
-
Riihimaki L, Galkin A, Finel M, Heikura J, Valkonen K, Virtanen V, Laak-sonen R, Slotte JP, Vuorela P (2007) Transport properties of bovine and reindeer beta-lactoglobulin in the Caco-2 cell model. Int J Pharm 347: 1-8.
-
(2007)
Int J Pharm
, vol.347
, pp. 1-8
-
-
Riihimaki, L.1
Galkin, A.2
Finel, M.3
Heikura, J.4
Valkonen, K.5
Virtanen, V.6
Laak-sonen, R.7
Slotte, J.P.8
Vuorela, P.9
-
40
-
-
0031158805
-
The physiological function of drag-transporting P-gly-coproteins
-
Schinkel AH (1997) The physiological function of drag-transporting P-gly-coproteins. Semin Cancer Biol 8: 161-170.
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
41
-
-
34547663275
-
Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vin-blastine-induced Caco-2 cell lines
-
Siissalo S, Laitinen L, Koljonen M, Vellonen K, Kortejärvi H, Urtti A, Hirvonen J, Kaukonen AM (2007) Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vin-blastine-induced Caco-2 cell lines. Eur J Pharm Biopharm 67: 548-554.
-
(2007)
Eur J Pharm Biopharm
, vol.67
, pp. 548-554
-
-
Siissalo, S.1
Laitinen, L.2
Koljonen, M.3
Vellonen, K.4
Kortejärvi, H.5
Urtti, A.6
Hirvonen, J.7
Kaukonen, A.M.8
-
42
-
-
0028358657
-
pH-dependent and carrier-mediated transport of salicylic acid across Caco-2 cells
-
Takanaga H, Tamai I, Tsuji A (1994) pH-dependent and carrier-mediated transport of salicylic acid across Caco-2 cells. J Pharm Pharmacol 46: 567-570.
-
(1994)
J Pharm Pharmacol
, vol.46
, pp. 567-570
-
-
Takanaga, H.1
Tamai, I.2
Tsuji, A.3
-
43
-
-
0029117415
-
Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids
-
Tamai I, Takanaga H, Maeda H, Sai Y, Ogihara T, Higashida H, Tsuji A (1995) Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids. Biochem Biophys Res Commun 214: 482-489.
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 482-489
-
-
Tamai, I.1
Takanaga, H.2
Maeda, H.3
Sai, Y.4
Ogihara, T.5
Higashida, H.6
Tsuji, A.7
-
44
-
-
2142714474
-
Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospho-lipid vesicles
-
Tammela P, Laitinen L, Galkin A, Wennberg T, Heczko R, Vuorela H, Slotte JP, Vuorela P (2004) Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospho-lipid vesicles. Arch Biochem Biophys 425: 193-199.
-
(2004)
Arch Biochem Biophys
, vol.425
, pp. 193-199
-
-
Tammela, P.1
Laitinen, L.2
Galkin, A.3
Wennberg, T.4
Heczko, R.5
Vuorela, H.6
Slotte, J.P.7
Vuorela, P.8
-
45
-
-
0041402720
-
Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: Asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers
-
Troutman MD, Thakker DR (2003) Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers. Pharm Res 20: 1200-1209.
-
(2003)
Pharm Res
, vol.20
, pp. 1200-1209
-
-
Troutman, M.D.1
Thakker, D.R.2
-
46
-
-
0028029150
-
Transcellular transport of benzoic acid across Caco-2 cells by a pH-dependent and carrier-mediated transport mechanism
-
Tsuji A, Takanaga H, Tamai I, Terasaki T (1994) Transcellular transport of benzoic acid across Caco-2 cells by a pH-dependent and carrier-mediated transport mechanism. Pharm Res 11: 30-37.
-
(1994)
Pharm Res
, vol.11
, pp. 30-37
-
-
Tsuji, A.1
Takanaga, H.2
Tamai, I.3
Terasaki, T.4
-
47
-
-
0019430432
-
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
-
Tsumo T, Iida H, Tsukagoshi S, Sakurai Y (1981) Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res 41: 1967-1972.
-
(1981)
Cancer Res
, vol.41
, pp. 1967-1972
-
-
Tsumo, T.1
Iida, H.2
Tsukagoshi, S.3
Sakurai, Y.4
-
48
-
-
46849092914
-
-
Center for Drag Evaluation and Research (CDER, ) Guidance for industry, waiver of in vivo bioavailability and bioequiva-lence studies for immediate-release solid dosage forms based on a bio-pharmaceutics classification system
-
U.S. Department of Health and Human Services, Food and Drag Administration, Center for Drag Evaluation and Research (CDER) (2000) Guidance for industry, waiver of in vivo bioavailability and bioequiva-lence studies for immediate-release solid dosage forms based on a bio-pharmaceutics classification system, (http://www.fda.gov/cder/guidance/3618fnl.htm).
-
(2000)
Food and Drag Administration
-
-
-
49
-
-
0342762062
-
The barrier function of CYP3A4 and P-glycoprotein in the small bowel
-
Watkins PB (1997) The barrier function of CYP3A4 and P-glycoprotein in the small bowel. Adv Drag Deliv Rev 27: 161-170.
-
(1997)
Adv Drag Deliv Rev
, vol.27
, pp. 161-170
-
-
Watkins, P.B.1
-
50
-
-
0034031969
-
Optimized conditions for prediction of intestinal drag permeability using Caco-2 cells
-
Yamashita S, Furubayashi T, Kataoka M, Sakane T, Sezaki H, Tokuda H (2000) Optimized conditions for prediction of intestinal drag permeability using Caco-2 cells. Eur J Pharm Sci 10: 195-204.
-
(2000)
Eur J Pharm Sci
, vol.10
, pp. 195-204
-
-
Yamashita, S.1
Furubayashi, T.2
Kataoka, M.3
Sakane, T.4
Sezaki, H.5
Tokuda, H.6
-
51
-
-
0036278361
-
New and better protocols for a short-term Caco-2 cell culture system
-
Yamashita S, Konishi K, Yamazaki Y, Taki Y, Sakane T, Sezaki H, Furuyama Y (2002) New and better protocols for a short-term Caco-2 cell culture system. J Pharm Sci 91: 669-679.
-
(2002)
J Pharm Sci
, vol.91
, pp. 669-679
-
-
Yamashita, S.1
Konishi, K.2
Yamazaki, Y.3
Taki, Y.4
Sakane, T.5
Sezaki, H.6
Furuyama, Y.7
-
52
-
-
0030963896
-
Evidence for diminished functional expression of intestinal transporters in Caco-2 cell monolayers at high passages
-
Yu H, Cook TJ, Sinko PJ (1997) Evidence for diminished functional expression of intestinal transporters in Caco-2 cell monolayers at high passages. Pharm Res 14: 757-762.
-
(1997)
Pharm Res
, vol.14
, pp. 757-762
-
-
Yu, H.1
Cook, T.J.2
Sinko, P.J.3
|